Beta cell replacement through transplantation remains the only treatment option for Type 1 diabetes enabling restoration of near-physiological glucose levels without significant hypoglycemia. Outlining the most recent advances and research breakthroughs, this practical guide and reference work explores the impact of islet cell transplantation and brings together leading multidisciplinary proponents critical to future success in the field. Edited by a surgeon and an endocrinologist at the forefront of the technology, this volume considers challenges associated with this procedure including lack of sufficient donor organs and the side effects of immunosuppressive therapy, as well as the potential benefits for current and future patients. Islet Transplantation and Beta Cell Replacement Therapy, after a brief historical overview, examines: the key role of endocrinologists in holistic assessment and selection of islet transplant recipients the factors underlying attrition of islet function over time and need for enhanced graft monitoring post transplantation future in vivo islet imaging setting up new clinical islet transplant programs by outlining potential models and pitfalls-including cost effectiveness and sustainable integrated approaches clinical outcomes and the future direction for islet transplantation, including alternative sources of beta cells, to meet future clinical needs through xenotransplantation, new insulin-producing cells from adult tissue, and stem cell banks

Edited by leaders at one of the acclaimed transplant institutions in the United States, this reference covers all aspects of living donor solid organ and cellular transplantation in current clinical practice, including the kidney, liver, pancreas, lung, small bowel, islet, and hematopoietic stem cell transplantation. Detailed, engaging, and organ- and cell-specific chapters cover guidelines for donor and recipient selection and evaluation, recent surgical techniques, and an assessment of donor risks and long-term patient outcomes.

Hand and wrist surgery is evolving rapidly and often, advances are directed at developing procedures that are less invasive, with smaller incisions and shorter rehabilitation times. Minimally Invasive Hand and Wrist Surgery is the only book devoted exclusively to these exciting new percutaneous and minimal access techniques for the treatment of chronic and traumatic conditions of the hand and wrist. Nearly forty procedures are described, with step-by-step details and abundant illustrations, all contributed by the leading international experts who are pioneering these new approaches.

Your surgical attachment is fast approaching and you have a number of questions that need answering to help you make the most of your experience... Making Sense of Your Surgical Attachment will answer them for you. Everything you need to know about the operating theatre and the use of surgical instruments is packed into this one handy guide: * The names and functions of surgical instruments * Electrosurgery and its techniques * How to use laparoscopic equipment * Sutures - put your best knot forward! * Operating theatre conduct and etiquette, and 'do's and don'ts' when assisting * How to scrub up * Pre-operative and peri-operative care * The surgical career ladder and how to climb it. With a foreword by Andrew Raftery, Chair of the Royal College of Surgeons of England's Medical Students Liaison Committee, Making Sense of Your Surgical Attachment offers an engaging insight into the practical aspects of surgery.

Originally published in 2007 and now available for the first time in paperback format, Head and Neck Manifestations of Systemic Disease presents critical information on a multitude of maladies that have manifestations in the head and neck. The book relates commonly encountered head and neck symptoms and signs to an array of diseases and disorders that should be considered in the differential diagnosis. Offering a hands-on approach, this volume addresses specific disease classifications and commonly encountered signs and symptoms in the head and neck region. It offers a clinical approach to disease diagnosis by analyzing the possible causes of a patient's symptoms. The contributors present evidence-based therapeutic options for a variety of conditions, from infections and rheumatologic conditions to hematologic and neoplastic disease. Organized by disease type for easy reference, the book offers a variety of lucid color photographs, providing a unique reference for clinicians who manage diseases with symptoms in this region.

Objective Structured Clinical Examinations (OSCEs) are commonly encountered at all levels of medical school including the final MBBS examination. OSCEs also play an important role at postgraduate level and are used to assess competency in the Foundation Years. One of the fundamental requirements of passing the OSCE is an understanding of the standard which is expected and an appreciation of how to demonstrate this. This book discusses 170 commonly encountered OSCE scenarios, with a step-by-step approach to maximise your chances of success in the examination. The scenarios are presented with sufficient background information to enable candidates to tackle variations. This comprehensive book, covering both surgery and medicine, overcomes any problems of a tick-box approach and insufficient detail faced by some alternative texts. The clear, straight-forward style and logical layout make this book perfect preparation for OSCE examinations.

Representing the vanguard in the field with practical case studies, authoritative recommendations, and a collection of best practices in operative and non-operative treatment, this reference offers step-by-step guidance in the correction and care of fractures affecting the actabulum and pelvis. Detailing procedures in pre- and postoperative planning, fracture imaging, reconstruction, and fixation, this source will serve the needs of specialists in orthopedic surgery and trauma, sports medicine, and emergency room settings.

Covering the gamut of new technologies and advancements related to limb lengthening and reconstruction, this source offers authoritative contributions from key opinion leaders on acute trauma; post-traumatic reconstruction; tumors; stature lengthening; and post-operative care provides expert surgical approaches for the hip, knee, foot, and ankle stands as a clear compendium of treatment guidelines for practitioners specializing in limb lengthening, reconstruction, and deformity correction includes tables outlining the authors' classification and treatment recommendations contains real-world technical tips and methods for complication management and avoidance, as well as an abundance of clinical case examples organizes each chapter to include principles, a practical approach to each subject, and a review of the recent literature An illustrative and in-depth overview of the many available applications and techniques for limb lengthening and reconstruction, this guide provides step-by-step details on the latest surgical procedures for the correction of limb deformities due to congenital defects, growth disturbances, infection, and trauma in both children and adults. Supplying effective surgical approaches, technical tips, methods to manage complications, and clinical case studies in each chapter, this guide will be a constant companion for all orthopedic, reconstructive, pediatric, foot, ankle, upper extremity, tumor, and trauma surgeons.

Cardiac surgery is one of the most frequently performed operations in the US. This all-inclusive guide examines the epidemiology, pathophysiology, diagnosis, & management of perioperative myocardial injury & infarction, & provides an assessment of the latest methods & strategies for optimal patient care & management.

With contributions from more than 100 renowned authorities in the field, this reference compiles treatment recommendations and tips for a myriad of complications associated with nonoperative and operative management of various spinal pathologies in children and adults-providing expert guidance on complication identification, recognition, management, and prevention, as well as the legal and ethical aspects of contemporary spinal care.

This source is an excellent introduction for the medical student, intern, resident, and private practitioner trying to learn a new Ob/Gyn procedure. The sections on important procedures teach how to perform the surgery and how it needs to be transcribed for the medical record. This revised, up-to-date guide will be essential for Ob/Gyn surgeons for performing common, uncommon, and new surgical procedures.

A 64-year-old woman has been referred to the on-call general surgical team by her GP. She has been complaining of pain in the upper part of her abdomen and generalized itching. Her daughter has also noticed a yellowish discolouration of her skin. The symptoms started a week ago and are gradually getting worse. You have been assigned her initial assessment... 100 Cases in Surgery presents 100 scenarios requiring surgical treatment commonly seen by medical students and junior doctors in the emergency department or outpatient clinic. A succinct summary of the patient's history, examination, and initial investigations-including photographs where relevant-is followed by questions on the diagnosis and management of each case. The answer includes a detailed discussion on each topic, with further illustration where appropriate, providing an essential revision aid as well as a practical guide for students and junior doctors. Making speedy and appropriate clinical decisions, and choosing the best course of action to take as a result, is one of the most important and challenging parts of training to become a doctor. These true-to-life cases will teach students and junior doctors to recognize important surgical conditions, and help to develop their diagnostic and management skills.

Published in conjunction with the Federation of European Societies for Surgery of the Hand meeting, "Tendon Transfers in Reconstructive Hand Surgery" brings together a range of international experts to detail the practical and surgical implications of tendon transfers in a number of different clinical scenarios.;Highly illustrated, succinct, and easy to follow, this important text covers a variety of areas from advanced biomechanical modelling and predictions, to practical guidelines on how to actually perform the surgical procedures described.;Providing new surgeons with the tools to plan and execute sound tendon transfer procedures, this instructional coursebook will infuse the field with new and challenging ideas that will ultimately improve patient care.

Treatment of Advanced Heart Disease is an expansive and up-to-date guide to the diagnosis and treatment of heart failure in children and adults. Written by leading specialists, this source guides the clinician through the possible causes of heart disease and emphasizes potentially reversible etiologies, in addition to reviewing currently available therapies including drugs, devices, surgery, and research sure to impact the field for years to come.
Leads the reader through crucial treatment practices and strategies to sustain the lives of patients with severe heart disease.

Now in its fifth edition, the Oxford Handbook of Emergency Medicine is the essential rapid-reference guide to emergency medicine for everyone from junior doctors to specialist registrars, nurse practitioners, and paramedics. New and improved, the Handbook has been thoroughly revised throughout, with 100 extra illustrations and the latest guidelines and treatment advice, completely overhauled chapters on Medicine, Obstetrics and Gynaecology, and Paediatric emergencies, and new topics on treatment escalation, end-of-life care, and sepsis. Clear and concise, extensively updated, and packed with a host of new X-rays to aid identification and treatment, this Handbook has everything you need to thrive in the demanding world of emergency medicine today.

There are several possible solutions to the different problems presented with female patients who have been unable to conceive. This completely revised edition provides guidance on the technical aspects of diagnosis and explanations of treatment using a how to, when and why approach, incorporating new expanded sections on endometriosis and polycystic ovary syndrome. Illustrated throughout with tables and graphs as a source for easy reference for guidance and counselling in clinical decision making, it will be essential reading for all those working in the clinical practice setting within infertility, providing all the necessary information required for developing sound clinical judgement in the diagnosis and surgical management of structural abnormalities of the reproductive tract.

Presenting current perspectives on the physiology and metabolism of the critically ill, this reference demonstrates practical approaches for the preoperative, intraoperative, and postoperative care of the critically ill patient with an abundance of clearly laid-out figures, case studies, graphs, and charts.

Endometriosis is on a worldwide increase and carries with it serious implications for women's reproductive health. Endometriosis in Clinical Practice brings together international experts to demonstrate what is known about the condition and the corresponding clinical implications for the patient suffering from it. Unlike many other books on this subject that are geared towards the patient or excessively focused on research, this one also answers the questions and meets the needs of the diagnosing physician. With the aid of color illustrations, the book highlights clinical topics such as epidemiology, assessment of health status, and endometriosis and ART. It covers everything you need to know about the disease, its diagnosis, and its management.