Surgery in Systemic Autoimmune Disease, Volume 15, describes the state-of-the-art of the use of surgery in treating the most common systemic autoimmune diseases (SADS). The volume consists of an introductory chapter concerning the impact of surgery on SADs, follow by eight chapters describing the use of surgery in the treatment of specific diseases in various areas (cardiology, gastroenterology, orthopedics, neurology. etc.) and the possible difficulties and complications. The final five chapters deal with the possible complications arising during the course of biological and non-biological treatment, also providing recommendation concerning their management. International in scope, the list of more than 20 contributors from Europa and America reads like a who's who of clinical researchers in the field.

Trigeminal neuralgia and other cranial neuralgias comprise a group of facial pain conditions, characterised by disabling pain attacks that selectively respond to specific treatments. Although not as common migraine, they affect over 1% of the population and must be recognised and adequately treated in clinical practice. The spectrum of cranial neuralgias is wide and as a consequence the conditions are managed by a range of different specialists. Studies show that delayed diagnoses and mismanagement are common and can lead to depression and suicide. 36 recognised experts from nine countries have contributed to OPML Trigeminal Neuralgia and Other Cranial Neuralgias to guide you through the maze of pathophysiology, clinical features, diagnosis-making, and condition-specific treatments. The approach is practical and evidence-based and ready for real-world applications. The value of phenotyping, targeted investigations, and treatment algorithms is emphasised. The editors and contributors subscribe to the view that there needs to be a holistic approach with multidisciplinary teams working together and with patients being at the centre of this process. Psychologists and patent support groups can help to ensure that patients are managed holistically and share the decision-making process. Their involvement in the handbook has helped to emphasis this. There remain considerable challenges, but the field is rapidly evolving and there are increasing number of opportunities opening up to improve our understanding of these conditions and hence their management. The editors and contributors have included case scenarios, algorithms, self-administered tools for training in diagnosis and management, clinical tips and carefully chosen references. Each chapter includes a lay summary and key points and can be read as a stand-alone unit.

This issue of Oral and Maxillofacial Surgery Clinics of North America focuses on Coagulopathy, and is edited by Drs. Jeffrey Bennett and Elie Ferneini. Articles will include: Perioperative Patient Evaluation: What the Oral Surgeon Needs to Know; Hypercoagulable States: What the Oral Surgeon Needs to Know; ASA, Plavix, and Other Antiplatelet Medications: What the Oral Surgeon Needs to Know; Heparin and Lovenox: What the Oral Surgeon Needs to Know; Blood Products: What the Oral Surgeon Needs to Know; Interventional Radiology and Bleeding Disorders: What the Oral Surgeon Needs to Know; Platelet Disorders: What the Oral Surgeon Needs to Know; Systemic Disease and Bleeding disorders: What the Oral Surgeon Needs to Know; Hemophilia: What the Oral Surgeon Needs to Know; Damage Control Resuscitation: What the Oral Surgeon Needs to Know; Hemostasis Agents: What the Oral Surgeon Needs to Know; Coumadin and Newer Agents: What the Oral Surgeon Needs to Know; and more!

Foot and ankle arthroscopy involves the surgical evaluation and treatment of the foot and ankle for a variety of conditions. This issue will cover everything from Arthroscopic Anatomy, Arthroscopic Instrumentation, Imaging Aspects of Joint Pathology and Arthroscopic Techniques, Intra-articular Soft Tissue Pathology, to Subtalar Joint Arthroscopy, and many more exciting articles.

This comprehensive book on Endocrine Surgery covers disorders of thyroid, parathyroid, adrenal glands along with neuroendocrine tumors of pancreas and gastrointestinal tract. It is a comprehensive, up-to-date treatise covering embryology, anatomy, etiology, clinical manifestations, diagnoses, and treatment modalities of surgical endocrine diseases. The authors explore the pertinent surgical endocrinology topics with a South Asian perspective. Color illustrations, flowcharts and tables make the topics lucid for professionals. This book provides the essential information surgeons require for evaluation and management of patients, both with straight forward, and complex endocrine problems. Key Features Focusses on concise yet comprehensive, up-to-date coverage of surgical endocrine diseases Discusses Robot Assisted Endocrine Surgery and explores its impact on healthcare finances Highlights the difference between practices used in western and resource limited countries by incorporating a South Asian perspective for region specific diseases.

This issue of Otolaryngologic Clinics of North America, devoted to Endoscopic Ear and Eustachian Tube Surgery, is guest edited by Drs. Joao Flavio Nogueira and Muaaz Tarabichi. Articles in this outstanding issue include: Anatomy of the Eustachian Tube; Physiology of the Eustachian Tube; Eustachian Tube Function and Testing; Radiology of the Eustachian Tube; Middle Ear and Eustachian Tube Dysfunction; Endoscopic Eustachian Tube Transnasal Surgery; Endoscopic Anatomy of the Protympanic Space; Outcomes Following Endoscopic Ear Surgery; Endoscopic Management of Superior Semicircular Canal Dehiscence; Endoscopic Management of Tumors in Middle Ear and Mastoid; Outcomes Following Endoscopic Stapes Surgery; Transtympanic Balloon Dilation of the Eustachian Tube; Selective Dysventilation Syndrome; Restoring Petrous Bone Ventilation; and Endoscopic Techniques in Tympanoplasty.

The Guest Editors have created a comprehensive issue devoted to the most current and clinically relevant approach to hysterectomies and their alternatives. Top experts have written articles on the following topics: Alternatives to Hysterectomy: Management of Uterine Fibroids; Alternatives to Hysterectomy: Management of Menorrhagia; Hysterectomy for benign conditions of the uterus: Total Abdominal Hysterectomy; Hysterectomy for benign conditions of the uterus: Total Vaginal Hysterectomy; Hysterectomy for benign conditions of the uterus: Total Laparoscopic Hysterectomy/Laparoscopically Assisted Vaginal Hysterectomy; Hysterectomy for benign conditions of the uterus: Radical Hysterectomy Evidence basis for hysterectomy; Cesarean Hysterectomy; Management of ovaries at the time of benign Hysterectomy; Management of the peri- and postoperative patient undergoing hysterectomy; and Simulation and surgical competency: Current issues.

This issue of Oral and Maxillofacial Surgery Clinics of North America focuses on Orofacial Pain, and is edited by Dr. Steven Scrivani. Articles will include: Classification and Differential Diagnosis or Orofacial Pain; Psychological Assessment for Chronic Orofacial Pain; Myofascial Pain Disorders; Disorders of the Temporomandibular Joints; Headache and Orofacial Pain; Neuropathic Orofacial Pain; Burning Mouth Syndrome; Orofacial Movement Disorder; Pharmacological Management of Orofacial Pain; Behavioral Medicine for Chronic Orofacial Pain; Injection Therapy for Headache and Facial Pain; Cranial Neuralgias; Intraoral Pain Disorders, and more!

The Year Book of Surgery brings you abstracts of the articles that reported the year's breakthrough developments in general surgery, carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. The Year Book of Surgery is published annually in June, and includes topics such as: General Surgery; Trauma; Burns; Critical Care; Transplantation; Surgical Infections; Would Healing; Oncology; Vascular Surgery; and General Thoracic Surgery.

This textbook is an introduction and guide to undergraduate surgery. It has been a bestseller since its first edition in 2001.The philosophy of this book is to focus on the level of knowledge and the approach that would be expected of the better students reaching the end of their undergraduate training. Avoiding a book that is too cumbersome, we have tried to make this volume readable and enjoyable, using various techniques to help the reader remember key facts: the text has been deliberately written in a tutorial-like story format as opposed to a set of lists, since this makes it easier to understand and remember.In addition to general surgery, the book contains sections on trauma, orthopaedics, urology and ENT, making it the only comprehensive textbook for medical students wishing to learn top tips in surgery.Subjects that are poorly covered in other main texts - such as fluid balance management and minor surgical procedures - are dealt with in a tutorial fashion in this book, and there is a section on how to problem-solve even in the context of areas unknown to the student.This book is useful for medical students and also for junior doctors during their day-to-day working lives, as well as those coming up to postgraduate exams.Each chapter is written by an authoritative author, alongside the book editors, and they have ensured it remains in the spirit of the bestselling previous editions.

This issue of Oral and Maxillofacial Surgery Clinics of North America focuses on Management of the Cleft Patient. Articles will include: Final Nasal Surgery; Prenatal Counseling, Ultrasound Diagnosis, and the Role of Maternal/Fetal Medicine of the Cleft Lip and Palate Patient; International Missions: Establishing a Longitudinal and Sustainable Team Approach; Diagnosis and Surgical Management of Velopharanyngeal Insufficiency; Feeding Infants with Clefts and Post-operative Management of the Infant Cleft Lip and Palate; Funding Cleft Patients in Need/Foundation and Fundraising; Latham Alveolar Molding and Presurgical Nasoalveolar Molding; Surgical Management of Tessier Facial Clefts; Otologic Concerns for Cleft Lip and Palate Patients; Distraction for Large Maxillary Anterior-Posterior Discrepancy in Cleft Patients; and more!

This issue of Surgical Oncology Clinics of North America, guest edited by Nipun Merchant, MD, is devoted to Pancreatic Neoplasms. Dr. Merchant has assembled expert authors to review the following topics: Molecular and Genetic Basis of Pancreatic Carcinogenesis: Which Concepts May Be Clinically Relevant?; Role Of EUS and ERCP In The Clinical Assessment Of Pancreatic Neoplasms; Optimal Imaging Modalities For The Diagnosis and Staging Of Periampullary Lesions; Advances in the Surgical Management of Resectable and Borderline Resectable Pancreatic Cancer; Minimally Invasive Approaches to Pancreatic Surgery; Adjuvant and Neoadjuvant Therapy for Pancreatic Cancer; Palliative Management of Unresectable Pancreatic Cancer; Spectrum and Classification of Cystic Lesions of the Pancreas; Therapeutic Approach to Cystic Neoplasms of the Pancreas; Clinical Presentation and Management of Pancreatic Neuroendocrine Tumors; State-of-the-Art Imaging of Pancreatic Neuroendocrine Tumors; Surgical Approaches to Pancreatic Neuroendocrine Tumors; and Medical Management of Pancreatic Neuroendocrine Tumors: Current and Future Therapy.

This first open access European CAR-T Handbook, co-promoted by the European Society for Blood and Marrow Transplantation (EBMT) and the European Hematology Association (EHA), covers several aspects of CAR-T cell treatments, including the underlying biology, indications, management of side-effects, access and manufacturing issues. This book, written by leading experts in the field to enhance readers' knowledge and practice skills, provides an unparalleled overview of the CAR-T cell technology and its application in clinical care, to enhance readers' knowledge and practice skills.

This book offers a thorough, clinically oriented review of hemostasis and its impact on the practice of dentistry. Readers will gain a sound understanding of the pathophysiology of hemostasis and the pharmacology of antithrombotic and prothrombotic medications. Perioperative dental management strategies of value in patients with different congenital and acquired disorders of hemostasis are carefully explained, and the role of surgical techniques and local and topical agents in helping to minimize and control bleeding is described. Helpful instruction is also provided on the indications for antithrombotic medications and the management of patients receiving such therapy, including the risks of altering medications. As the number of available oral antithrombotic agents continues to increase, dentists will encounter significantly more patients receiving treatments that affect hemostasis. In presenting comprehensive, up-to-date information on hemostasis, hemostatic disorders, antithrombotic therapy, and safe dental management, this book will serve as a rich source of information and a useful guide for practitioners and students alike.

This issue of Surgical Clinics of North America, guest edited by Dr. Clifford Cho, is devoted to Technical Aspects of Oncological Hepatic Surgery. He has assembled expert authors to review the following topics: Determination of Resectability; Radiographic Characterization of Hepatic Tumors; Chemotherapy-associated Hepatotoxicity; Preoperative Assessment and Optimization of the Future Liver Remnant; Anatomy of Hepatic Resectional Surgery; Resection of Gallbladder Carcinoma; Resection of Hilar Cholangiocarcinoma; Technical Aspects of Orthotopic Liver Transplantation for Hepatocellular Carcinoma; Hemostasis and Hepatic Surgery; Minimally Invasive Hepatic Surgery; Hepatic Tumor Ablation; Hepatic Transarterial Therapies; Hepatic Perfusion Therapy; Hepatic Artery Infusional Chemotherapy; Ex vivo Hepatic Surgery, and more!

This issue of Oral and Maxillofacial Surgery Clinics of North America focuses on Pediatric Oral and Maxillofacial Pathology. Articles will include: Benign soft tissue pathology, Malignant head and neck pathology, Odontogenic cysts of the jaws, Non-odontogenic cysts of the jaws, Odontogenic tumors of the jaws, Non-odontogenic tumors of the jaws, Benign salivary gland pathology, Malignant salivary gland pathology, Vascular malformations and treatment, Vascular tumors of the head and neck, Radiotherapy to the head and neck and the growing patient, Chemotherapy for tumors of the head and neck in the growing patient, and more!

Head and neck pathology is increasingly becoming an attractive field for the new generations of pathologists, fully aware that in the era of specialization the information contained in the treatise of general surgical pathology, although extremely valuable to create the basis of their knowledge, does not provide in its full picture the specific knowledge required to meet current diagnostic and prognostic requirements. The book Pathology of the Head and Neck presents in a single volume the most pertinent and updated information needed by the interested readers. Its contents have been divided into ten chapters. The first one covers the spectrum of precursor and neoplastic lesions of the squamous epithelium. It is followed by chapters devoted to nasal cavities and paranasal sinuses, oral cavity, maxillofacial skeleton and teeth, salivary glands, nasopharynx and Waldeyers ring, larynx and hypopharynx, ear and temporal bone, neck and neck dissection, as well as eye and ocular adnexa. The authors of the different chapters have been selected among internationally recognized experts, all of them members of the Working Group on Head and Neck Pathology of the European Society of Pathology.

Editor Salvatore Ruggiero, DMD, MD and authors review the Diagnosis, Management and Prevention of Medication-related Osteonecrosis of the Jaw. Articles will include: Osteoporosis and bone modulation therapies: indications and outcomes; Antiresorptive therapies for the treatment of malignant osteolytic bone disease; Clinical presentation and staging of antiresorptive agent-induced osteonecrosis of the jaw; Epidemiology and risk factors of antiresorptive agent-induced osteonecrosis of the jaw; Basic science research of antiresorptive agent-induced osteonecrosis of the jaw: an update; Pathophysiology of antiresorptive agent-induced osteonecrosis of the jaw: what we know and what we don't know; The genetics of osteonecrosis of the jaw; Preventive strategies for patients at risk of antiresorptive agent-induced osteonecrosis of the jaw; Non-operative and operative therapies for treatment of antiresorptive agent-induced osteonecrosis of the jaw; The role of anti-angiogenic therapy in the development of osteonecrosis of the jaw; Antiresorptive therapies: what they are and how do they work, and more!

This book combines the complexities of neuro-ophthalmologic and neuro-otologic disorders into one concise guidebook. It focuses on the basics of these two challenging subspecialties, encountered by the neurologist, ophthalmologist, otolaryngologist, neurosurgeon, emergency medicine provider, and others. Comprehensive and succinct, the book contains chapters examining representative case vignettes that highlight typical historical elements and exam findings that aid in diagnosing a specific disease, disorder, or syndrome. Before each heading, chapters offer a brief review of relevant anatomy, physiology, and examination techniques. Additionally, symptom-based tables guide the practitioner to a focused history and examination for rapid real-time triage and diagnosis. Practical and case-based, Neuro-Ophthalmology and Neuro-Otology is an invaluable resource for practitioners, trainees, and residents in various fields.

This textbook details the latest diagnostic and management options available when treating patients with diseases affecting the oral mucosa. It comprehensively covers the content required to successfully pass dermatology and stomatology board examinations, while being a valuable resource for dentistry trainees. Chapters cover aspects of mucosal immunity and clinical scores along with a range of diseases. Didactic features including learning objectives enable the reader to better extrapolate the key concepts covered in each chapter. Diseases of the Oral Mucosa: Study Guide and Review presents an in depth overview of the latest diagnostic tools and management options available for diseases of the oral mucosa and is an ideal resource for trainee and practising dentists, dermatologists and stomatologists preparing to sit board examinations.

This issue of Surgical Pathology Clinics takes a departure from its presentation of Differential Diagnosis, Histopathology, Staging, and Prognosis of tumors in different anatomic sites. This special issue is devoted to topics in pathology informatics as they relate to the practice of surgical pathology. Topics include: Basics of Information Systems (Hardware, Software); Networks, Interfaces and Communications; Databases; Data Representation, Coding and Communication Standards; Laboratory Information Systems; Enhancing and Customizing Laboratory Information Systems to Improve/Enhance Pathologist Workflow; Laboratory Management and Operations; Specialized Laboratory Information Systems; Middleware and Laboratory Automation; Synoptic Reporting in Anatomical Pathology; Bar Coding and Tracking; Molecular Pathology Informatics; Informatics and Autopsy Pathology; Pathology Informatics and Project Management; Digital Imaging Basics; Use of Digital Images in Clinical Practice; Whole Slide Imaging; Telepathology; Mobile Technologies for the Surgical Pathologist; Image Analysis; Advanced Imaging Techniques; Healthcare Information Systems; Data Security and Reliability; Role of Informatics in Patient Safety and Quality Assurance; Role of Pathology Informatics in IT Leadership; Selection and Implementation of New Information Systems; Biomedical Informatics and Research Informatics; Training in Pathology Informatics; and Building Tools for the Surgical Pathologist: Next Generation Pathologist. Editor of this issue, Dr Anil Parwani, is Professor of Pathology and Biomedical Informatics and Director of Division of Pathology Informatics. Dr. Parwani is well known as expert in the area of Anatomical Pathology Informatics, which includes design of quality assurance tools, tissue banking informatics, clinical and research data integration and mining, synoptic reporting in anatomical pathology, clinical applications of whole slide imaging, digital imaging, telepathology, image analysis and lab automation and workflow processes, such as barcoding and voice recognition.

This issue on endoscopic cranial base and pituitary surgery is led by experts in the field of Otolaryngology and Neurosurgery. Otolaryngologists/Head and Neck surgeons Dr. Raj Sindwani and Dr. Troy Woodard join with Neurosurgeon Dr. Pablo Recinos to present a comprehensive clinical approach. Topics include: Building an endoscopic skull base program (room setup and key equipment / IGS); Skull Base Anatomy (corridors, intra and extradural); Imaging in skull base surgery - CT, MRI, CT cisternogram, intraop CT; Sellar lesions / pathology; Principles of endoscopic pituitary surgery ; Reconstruction of skull base defects - free graft, pedicle, TPF, alloderm; Lumbar drain utility (role of intrathecal fluorescein); Hemostasis in Skull Base Surgery (control of smaller vessels, maneuvers to minimize bleeding - warm irrigations, HOB up, embolization); Management of ICA Injury (intraop options, late complications); Meningioma; Esthesioneuroblastoma; Cordoma; Sinonasal Malignancies of Skull Base; Craniopharyngioma; Endonasal approaches to the craniocervical junction; Medical complications of Pituitary/skull base surgery - (ie. SIADH, DI, Hypopit); Post-op management of skull base patient (postop Abx, imaging, debridements, topical irrigations, more...). Articles cover surgical procedure, surgical complications, and surgical anatomy as relevant to the clinical discussion.

Editors Daniel B. Spagnoli, Brian B. Farrell, and Myron R. Tucker review important areas in Orthognathic Surgery. Articles will include: Timing of Three-Dimensional Virtual Treatment Planning of Orthognathic Surgery: a Prospective Single-Surgeon Evaluation on 350 Consecutive Cases; Orthodontic Preparation for Orthognathic Surgery; Applications of Navigation for Orthognathic Surgery; Mandibular Surgery: Technologic and Technical Improvements; Maxillary Orthognathic Surgery; Surgical Assistance for Rapid Orthodontic Treatment and Temporary Skeletal Anchorage; Management of Cleft Lip and Palate and Cleft Orthognathic Considerations; Orthognathic Surgery and the TMJ Patient; Complications in Orthognathic Surgery: Report of 1000 Cases; Orthognathic Surgery in the Office Setting; Esthetic Adjuncts with Orthognathic Surgery; Virtual Surgical Planning in Orthognathic Surgery; and more!

Simulation in Surgical Training and Practice is reviewed extensively in this important Surgical Clinics of North America issue. Articles include: Applying Educational Theory to Simulation Based Training and Assessment in Surgery; Figuring out Team Simulation Training; Faculty Development for Simulation Training; The Evolving Role of Simulation in Teaching Surgery in Undergraduate Medical Education; Using Simulation in Inter-Professional Education; Current Status of Simulation Based Training in Graduate Medical Education; National Simulation-based Training of Fellows: The Vascular Surgery Example; Paying For it: Funding Models for Simulation Centers; Surgical Simulation Centers as Educational Homes for Practicing Surgeons; Better Assessment: Advanced Engineering Technology for Measuring Performance In and Out of the Simulation Lab; Moving the Needle - Simulation's Impact on Patient Outcomes; Human Factors Engineering and Effective Simulation - Partners for Improved Patient Safety; Simulation for the Assessment and Improvement of Teamwork and Communication in the Operating Room; Using Simulation to Improve Systems; Simulation for Maintenance of Certification; and more!

The Yearbook of Hand and Upper Limb Surgery is an annual review of the year's most relevant articles pertaining to this specialty. World-recognized hand surgery experts provide commentary on their personal experience related to these published abstracts. This interactive format allows the resident, fellow, or practicing surgeon to become quickly updated in this rapidly-changing field. The portable book form allows this Yearbook to be carried anywhere for ease of use. On first reading, the hand surgeon can become familiar with the latest studies published. Thereafter, it can remain on the bookshelf for easy reference of that year's key articles.