This issue of Surgical Oncology Clinics of North America, guest edited by Dr. Michael I. D'Angelica, is devoted to Management of Metastatic Liver Tumors. Dr. D'Angelica has assembled expert authors to review the following topics: Surgical management of liver metastases of colorectal cancer; Surgical management of liver metastases of breast cancer; Surgical management of liver metastases of neuroendocrine tumors; Surgical management of liver metastases of sarcoma (including GIST); Surgical management of liver metastases of gynecologic cancers; Surgical management of liver metastases of genitourinary cancers; Surgical management of liver metastases of uveal and dermal melanoma; Is there a role for locoregional therapies for non-colorectal GI malignancies?; Intra-arterial chemotherapy for liver metastases; External beam radiation for liver metastases; Isolated hepatic perfusion for liver metastases; Debate: Improvements in systemic therapies for liver metastases will soon render locoregional treatments obsolete; Debate: Improvements in systemic therapies for liver metastases will increase the role of locoregional treatments; and more!

In this issue of Oral and Maxillofacial Surgery Clinics, guest editors Jonathan Martin brings his considerable expertise to the topic of Management of Soft Tissue Trauma. Provides in-depth, clinical reviews on Management of Soft Tissue Trauma, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

This is an interdisciplinary book which for the first time assembles the wide spectrum of information on the basic and clinical aspects of the natural anti-Gal antibody, the alpha-gal epitope and the enzyme producing it, alpha-1,3-galactosyltransferase. Anti-Gal is the most abundant antibody in humans, apes and Old World monkeys (monkeys of Asia and Africa). It binds specifically to the alpha-gal epitope (Galalpha1-3Galbeta1-4GlcNAc-R) on glycoproteins and glycolipids. Humans, apes and Old World monkeys lack alpha-gal epitopes. In contrast, the alpha-gal epitope is produced in large amounts on cells of nonprimate mammals prosimians and New World monkeys (monkeys of South America), by the glycosylation enzyme alpha-1,3-galactosyltransferase. This differential distribution of the alpha-gal epitope and anti-Gal in mammals is the result of an evolutionary selective process which led to the inactivation of alpha-1,3-galactosyltransferase in ancestral Old World primates. A direct outcome of this event is the present rejection of xenografts such as pig organs in humans and monkeys because of the binding of human anti-Gal to alpha-gal epitopes on pig cells. The various chapters in this book were contributed by researchers studying basic and clinically related aspects of this area. The book aims to provide comprehensive and updated information on this antigen/antibody system, which at present is the major obstacle in xenotransplantation, and on some of the genetic engineering approaches developed for overcoming this obstacle. In addition, this book describes the significance of anti-Gal and alpha-gal epitopes in some parasitic, bacterial and viral infections, as well as in the pathogenesis ofautoimmune diseases such as Graves' disease. Finally, this book describes novel approaches for exploiting the natural anti-Gal antibody for increasing immunogenicity of cancer and viral vaccines in humans. This book is edited and partly written by Dr. Uri Galili who originally discovered anti-Gal and the unique evolution of &agr;-1,3-galactosyltransferase, and by Dr. Jose-Luis Avila who has been studying anti-Gal significance in Chagas' disease and in Leishmania infections. This book covers the main areas of research on &agr;-1,3galactosyltransferase, its product the &agr;-gal epitope (Gal&agr;1-3Gal&bgr;1-4GlcNAc-R) and the natural anti-Gal antibody that interacts with this epitope. The book includes chapters on: The evolution of &agr;-1,3 galactosyltransferase in mammals; the structure of the &agr;-1,3galactosyltransferase gene; the structure function relationship of the &agr; 1,3galactosyltransferase enzyme; the molecular characteristics of &agr;-gal epitopes on glycolipids and glycoproteins and methods for its detection; the natural anti-Gal antibody and its significance in xenotransplantation; attempts to prevent xenograft rejection by elimination of &agr;-1,3galactosyltransferase gene, and by modulating &agr;-gal epitope expression and anti-Gal activity; significance of anti-Gal and &agr;-gal epitopes in viral, bacterial and protozoal infections; and the possible clinical exploitation of anti-Gal for the enhancement of cancer and viral vaccine immunogenicity.

THE 'GOLDEN JUBILEE' EDITION OF A CLASSIC TEXTBOOK, FIRST PUBLISHED IN 1965 Highly Commended at the British Medical Association Book Awards 2016 General Surgery Lecture Notes continues to be an invaluable, appealing and approachable resource for thousands of medical students and surgical trainees throughout the world. This comprehensive guide focuses on the fundamentals of general surgery, and systematically covers all the clinical surgical problems that a student may encounter and about which they need to know. Fully revised and updated to reflect the rapid changes which are taking place in surgical practice, this 50th anniversary edition: * Includes principles of treatment written at student level to aid understanding * Features full colour illustrations throughout * Includes electronic access to a range of extra material including case studies, images and photographs, and biographies * Includes free access to the Wiley E-Text * Is a perfect review text for medical students as well as junior surgeons taking the MRCS examination and other postgraduate surgical examinations Trusted by generations of medical students, the clinical emphasis of General Surgery Lecture Notes makes this an essential purchase for all those wishing to learn more about general surgery.

This book describes the surgical bariatric procedures most frequently performed worldwide and examines their evolution in recent years both within Italy and internationally. For each operation, indications, the surgical technique, potential complications, and the outcomes with respect to weight and obesity-associated comorbidities are presented. In view of the significant failure rate revealed by studies on the long-term results of bariatric surgery, the problem of weight regain and revision surgery are also discussed in detail, covering the different types of revision, conversion to other procedures, and the main outcomes. In addition, individual chapters focus on selected topics of importance. The role of bariatric surgery in the cure of type 2 diabetes ("diabetes surgery") is discussed and the debate over the significance of gastroesophageal reflux disease and hiatal hernia for choice of procedure is summarized. Finally, the most common endoluminal procedures, which have been gaining in importance, are described and other bariatric operations, outlined.

In the 6 years since the publication of the first volume of Recent Advances in Endourology by the Japanese Society of Endourology and ESWL, data on long-term oncological or functional outcomes have been collected in several related fields, and advances in surgical techniques and improved instrumentation have led to further development of such complex surgery as laparoscopic partial nephrectomy and radical prostatectomy. This seventh volume in the series focuses on the treatment of urogenital malignancies by endourological procedures, including laparoscopic surgery with robotic assistance. The standard procedures and their relatively long-term outcomes as well as new techniques have been clearly described with detailed references. This book provides a better understanding of the present status of endourological management for urogenital carcinoma and sets the stage for future improvements in both oncological and functional outcomes.

Cancer chemotherapy frequently attacks the gastrointestinal tract. Many of the possible side-effects reduce the patient's quality of life, may limit acceptance of further drug administration, and even life-threatening complications must be considered. This book is the proceedings of the Falk Workshop 'Side-effects of Chemotherapy on the Gastrointestinal Tract: Pathogenesis and Therapy', held in Freiburg, Germany, on October 11, 2002 (Part IV of the Freiburg Gastroenterology Week). Chapters by pathologists, pharmacologists, oncologists and gastroenterologists will improve our understanding of the effects of anticancer agents on the organs of the gastrointestinal tract and help to compensate for chemotherapy-induced adverse effects.

First Published in 1981, this book offers a full, comprehensive guide to experimental stomatology. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for students of medicine, and other practitioners in their respective fields.

Colorectal Surgery: Living Pathology in the Operating Room is two books in one. First, it is an atlas in the classic definition: each chapter is a two-page spread discussing one case. Functionally, each chapter is a case study with both the surgical and pathological perspectives beautifully rendered and fully explained. Visually, every chapter presents the reader with operative and/or diagnostic photos, and anatomic line drawings by the author. The text, more extensive than in many atlases, provides a concise yet complete operative record: patient history/work up, anatomic anomalies, the procedure itself, pathologic findings, and follow up. Key teaching points emphasize the most important and unique aspects of every case. Residents, fellows, and even seasoned practitioners will gain valuable diagnostic and therapeutic insights from this material. The case study presentation provides an excellent review tool for the American Board of Colon and Rectal Surgery exam.

Provides a concise and intuitive overview of the role of statistics in surgical practice. Uses no mathematics but includes narrative descriptions of statistical concepts. Includes topics of specific interest to surgeons. Provides real surgical examples to illustrate applications.

1.The Core Surgical Training interview has a format much closer to that of an exam than any 'traditional' job interview - this book covers the key aspects of this exam- interview. 2. Candidates using this book to revise and practice their answers to the common interview questions/scenarios will score the highest. 3. Easy to use A-Z format assists easy memorization of key facts.

In this issue, guest editors bring their considerable expertise to this important topic. Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize

Medical Tourism and Wellness: Hospitality Bridging Healthcare (H2H) takes a systems approach to examining the growing field of medical tourism, one of the field's hottest niches, with billions of dollars spent each year. This important book fills the need for a modern management book that looks at medical tourism in depth from a medical and hospitality operational management perspective. Growing numbers of people are going abroad to find affordable quality medical care for both necessary and cosmetic medical services. When they require surgery or dental work, they combine it with a trip to the Taj Mahal, a photo safari on the African veldt, or a stay at a luxury hotel-or at a hospital that feels like one-all at bargain-basement prices. The book takes a comprehensive look at medical tourism, covering such topics as: The history of medical tourism Why patients/tourists decide to travel for medical care The role of professional facilitators of medical tourism Key countries and medical disciplines in medical tourism Transportation, food, entertainment, and hotel/hospitality services Hotel and spa designs for medical tourism Best practices in medical tourism Patient follow-up after medical discharge Future trends in medical tourism Careers in medical tourism With the inclusion of case studies, the book provides a comprehensive look into this growing trend and will be valuable to upper-level undergraduate and graduate students in health care administration and those pursing MBAs in healthcare, medical students pursuing a management focus, and students in hospitality management. It will also be a must-have resource for professionals working in hotels and in health care.

An ever-increasing number of surgical procedures are now being performed in ambulatory settings. Hospital beds are at a premium and resources are becoming scarcer. This atlas guides readers through all the practicalities: it looks at the potential of short-stay surgery, how to set it up and how it may be relevant to all surgical specialities. Specialists well- known in their sphere discuss and illustrate operations that can be performed without a stay in hospital. The topics covered will become more and more relevant as time goes by, and those who read this book will be able to stay well ahead of the game. It is designed to help surgeons plan for the future and discover the vast potential for this form of surgery.

First published over 40 years ago, this is one of the best-established introductory texts for students of dentistry and oral and maxillofacial surgery. It covers each of the basic tenets of the specialty, from patient management to anxiety and pain control, to implant dentistry and maxillofacial trauma. The sixth edition has been thoroughly revised to reflect the latest developments in the field, and each chapter has been completely updated and restructured. New chapters specifically on implant dentistry have been included. This latest edition also features for the first time colour images of clinical procedures, clear colour diagrams and e-learning references.

This book is of undoubted value for students and recently qualified practitioners of dentistry, for whom it acts as a complete and ready reference through which to gain a firm foothold in oral and maxillofacial surgery.

Key features

- Covers each basic tenet of oral and maxillofacial surgery- Presents information in a clear and student-friendly style- Reflects latest developments in the field with updates throughout - Provides new chapters specifically on implant dentistry- Includes colour clinical photographs and diagrams

The advent of robotic surgery brought a rise in the proportion of minimally invasive surgery in gynecology. This book provides a practical guide to this innovative field. First it introduces the basics of robotic surgery and then focuses on specific gynecology-related surgeries. Gynecologists currently practicing robotic surgery as well as those who would like to include robotic surgery in their practice will benefit greatly from this book.

Cracking the Intercollegiate General Surgery FRCS Viva: A Revision Guide 2e provides the framework and knowledge to pass the non-subspecialty sections of the FRCS (General Surgery) viva and clinical examination. This comprehensive and up to date revision text covers all essential topics in critical care, emergency and general surgery as well as research papers, basic statistics and data manipulation for the academic section.This essential revision guide provides you with the vital points for each topic, presented in a concise, structured manner and referenced where appropriate. It is essential reading for anyone preparing for the FRCS General Surgery exam.

1.The Core Surgical Training interview has a format much closer to that of an exam than any 'traditional' job interview - this book covers the key aspects of this exam- interview. 2. Candidates using this book to revise and practice their answers to the common interview questions/scenarios will score the highest. 3. Easy to use A-Z format assists easy memorization of key facts.