Recognition of the importance of maternal medicine is now reflected in the content of the MRCOG exam, core training and higher training in both obstetrics and medicine. This book approaches obstetric medicine from the point of view of real patients and clinical scenarios as well as model answers to exam questions. The book will be invaluable for trainees and consultants who want to test themselves .

Ovarian carcinoma continues to be responsible for more deaths than all other gynecologic malignancies combined, due to a continued inability to achieve detection of early (rather than advanced) stage disease and the lack of effective tumor-specific therapeutics.

Ovarian carcinogenesis, invasion, and metastatic dissemination require a complex cascade of interrelated genetic, molecular, and biochemical events that regulate the neoplastic transition of normal ovarian surface epithelium.

This updated second edition includes exciting new advances in ovarian cancer detection and treatment and provides an analysis of current research into aspects of malignant transformation, growth control, and metastasis. A more detailed understanding of these processes may ultimately translate into the development of novel approaches for the detection and control of ovarian cancer.

Part of the World Clinics: Obstetrics & Gynecology series, this new volume presents clinicians and trainees with the latest developments in the diagnosis and management of anaemia. Beginning with an introduction to the classification, pathology and diagnosis of the condition, the following chapters cover different types of anaemia including iron deficiency, folic acid and Vitamin B12 deficiency, haemolytic, aplastic, sickle cell, and more. The book concludes with discussion on special situations such as severe anaemia in labour and antepartum haemorrhage. Presented as a collection of evidence-based reviews, each article is enhanced by photographs and figures, and concludes with a summary and comments by the editors highlighting their own clinical experience. Other volumes in the series include: Endometriosis, Polycystic Ovary Syndrome, Recurrent Miscarriage, Contraception, Ovulation Induction, Perimenopausal Health, Postpartum Hemorrhage, Preeclampsia, and Preterm Labor. Key points Latest volume in the World Clinics: Obstetrics & Gynecology series Covers diagnosis and management of different types of anaemia Each article concludes with a summary and comments by the editors Enhanced by photographs and figures throughout

The field of androgen excess disorders has advanced substantially since the original publication of this book. The Androgen Excess Society (AES) was founded to bring together investigators in the field. A better understanding of the screening, progression, and molecular genetics of nonclassic adrenal hyperplasia (NCAH) has improved the clinical care and diagnostic accuracy of these patients. New criteria for the diagnosis of the polycystic ovary syndrome (PCOS) were proposed in Rotterdam, criteria that have resulted in controversy and, hopefully, initiation of new studies. The association of insulin resistance with PCOS has been strengthened, and the role of metformin in tre- ing the infertility of the PCOS has been validated. Risks for diabetes and, more cont- versially, cardiovascular disease in women with PCOS have received substantial investigation. Our understanding of the epidemiology and economic impact of these disorders has expanded, emphasizing their critical importance. These are but a few highlights of how the terrain has changed in a relatively brief period of time. In keeping with these advances, the title of this book has been revised to reflect the growing importance of PCOS as the most prevalent androgen excess disorder in women, and arguably, as the one that might have the most serious adverse consequences for general health. There are fewer chapters to provide a more focused elucidation of the area. Several chapters were penned by new (and young) authors who are conducting cutting-edge research in the field.

This book is a guide to the diagnosis and management of gynaecological disorders for clinicians and trainees. Divided into 22 sections, the text begins with discussion on normal and abnormal puberty, then the physiology and symptoms of menopause. The following sections cover numerous gynaecological disorders, their symptoms, investigation, diagnosis, and treatment. The book covers both normal and abnormal symptoms, and offers guidance on when treatment may not be needed if a condition is benign. The comprehensive text is further enhanced by clinical photographs, diagrams and tables. Key points Comprehensive guide to diagnosis and management of common gynaecological conditions Covers both normal and abnormal symptoms Offer guidance on benign conditions where treatment may not be necessary Highly illustrated with clinical photographs, diagrams and tables

Gynaecology, Obstetrics, and Reproductive Medicine in Daily Practice is a unique publication aimed at the non-academic practicing gynaecologist, and students alike. The papers included in the book are written by invited speakers who attended the 15th Congress of Infertility, Gynaecology and Obstetrics. All the information is important to both doctors in training as well as qualified gynaecologists. Certain sections are interesting to fertility specialists as well as midwives. This is a useful tool to refresh and enhance skills in the fields of gynaecology, urogynaecology, obstetrics and reproductive medicine. The emphasis has been put on accomplishments achieved as opposed to ongoing controversies in the field. The book has a clear, primary target group. The book provides refresher and enhancing opportunities for all subspecialisations: gynaecology, urogynaecology, obstetrics and reproductive medicine Emphasis on the consensus achieved rather than ongoing controversies

This book has been launched to commemorate the 24th Annual Conference of Indian Society for Assisted Reproduction. It is a unique effort to gather experiences from experts from all over the world - all of whom are authorities in their respective field, to provide concise and updated information and integrated management approach to deal with different situations.

A complete and well-written manual that covers a large range of topics from basic physiology and primary management of infertility to the very latest in implantation and embryo selection and screening. The chapters are authored by the acknowledged masters in their field. Sections on polycystic ovarian syndrome (PCOS), male infertility, laboratory procedures in ART have been added to make it a comprehensive and easy daily reference book. The book ends with very thought provoking chapters dealing with adoption, counseling, medicolegal and ethical aspects, third party and cross border reproduction.

The new edition of this atlas integrates all significant advances made in the past 15 years in molecular pathology,tumor virology,and genetics of cervical cancer. It emphasizes the importance of these advances in facilitating its pathological diagnosis and in op- mizing clinical management and prognosis. A new chapter on immunohistochemistry has been added,which includes refined detection methods,e. g. ,the overexpression of INK4a p16 as a molecular marker in the early differential diagnosis of premalignant - sions. The section on etiology and pathogenesis in human papillomavirus-induced neoplasia has been incorporated to represent new insights into the sequences of cel- lar and nuclear deregulation at the molecular level. All chapters have been revised to - clude the newest advances and relevant experiences in how to interpret and manage cervical disease; they are supported by the addition of 35 new microphotographic ill- trations. The tumor nomenclature is adapted to the latest edition of the WHO classi- cation; the morphology code of the international classification of diseases for oncology (ICD-O) has been added. We have also updated the list of references by adding recent relevant publications. Again,the staff of Springer-Verlag deserve our thanks for their patience and skill in preparing the manuscript and in reproducing the microphotographs. Heidelberg,February 2005 Gisela Dallenbach-Hellweg, Magnus von Knebel Doeberitz, and Marcus J. Trunk Heading2 Preface to the First Edition During the past decade our understanding of the histopathology of the cervix uteri has changed greatly.

A comprehensive and practice-oriented resource guide to currently available diagnostic and treatment options for male infertility disorders. Topics covered range from basic sperm biology and male reproductive endocrinology, to immunology, specialized sperm testing, and the genetic background to male infertility. The authors emphasize the investigation, diagnostic testing, and management of the infertile male, but also examine such timely issues as gender selection, HIV discordance couples, and posthumous reproduction. Other topics of interest include laboratory accreditation, vasectomy reversal, ethical and legal considerations of donor insemination, optimizing success in a donor insemination program, and strategic therapies for ejaculatory disorders and erectile dysfunction in infertile men.

Recent years have seen many changes in human reproduction resulting from state and medical interventions in childbearing processes. Based on empirical work in a variety of societies and countries, this volume considers the relationship between reproductive processes (of fertility, pregnancy, childbirth and the postpartum period) on the one hand and attitudes, medical technologies and state health policies in diverse cultural contexts on the other.

This splendid volume presents numerous aspects of preterm labor and delivery, from its fundamental mechanism to clinically focused approaches. The incidence of preterm delivery is 6-7% in Japan, while globally up to 10% of pregnancies with preterm labor result in premature delivery. The rates of overall survival and intact survival of the premature infants are also excellent in Japan. Thus Japan's approach to preterm labor and delivery has long attracted attention. In each chapter, experts describe specific issues unique to conditions in Japan, including diagnosis, tocolytic agents, definition of clinical chorioamnionitis, treatment of bacterial vaginosis, role of amniocentesis, management of preterm premature membrane rupture and also placental pathology, presenting definitive evidence of the reduced incidence of preterm delivery in Japan. This book benefits not only obstetricians, pediatricians and gynecologist, but also midwives, nurse practitioners, and medical and associated staffs in the field of obstetrics, pediatrics, as well as neonatal and perinatal medicine who are involved in delivery.

Formulare, Antrage und mehr - Was ist wann, wie und wo zu beantragen Dieser nicht-medizinische Ratgeber fasst ausfuhrlich alle Informationen und Handlungsschritte zur finanziellen Absicherung und Klarung sozialrechtlicher Fragen wahrend und nach der Brustkrebserkrankung und -therapie zusammen. Die Autorin bundelt ihr Insiderwissen, die Ergebnisse intensiver Recherchearbeit sowie exakte Kenntnisse zu Gesetzestexten und einschlagigen Gerichtsurteilen in erforderlicher Tiefe und klart uber Rechte und Pflichten auf. Betroffene erhalten so einen konkreten und kompakten Handlungsleitfaden. AUS DEM INHALT Erfolgreich gegenuber Arbeitgeber, Behoerden, Versicherungen und anderen Institutionen behaupten und Rechte durchsetzen Sozialburokratische Hurden uberwinden bei Ersterkrankung und Rezidiv Konkrete Verweise auf aktuelle Gesetzestexte, Rechtsurteile sowie Links auf Formulare Steuerliche Hinweise und praktische Tipps DIE AUTORIN Frau Dr. Sandra Otto, geb. 1977, studierte zunachst Betriebswirtschaft in Jena und Jyvaskyla (Finnland). Nach einigen Stationen in der freien Wirtschaft promovierte sie im Bereich Rechnungslegung. Seit 2010 arbeitet Sandra Otto am Fraunhofer-Zentrum fur Mittel- und Osteuropa MOEZ in Leipzig. Die Diagnose Brustkrebs begleitet sie seit 2011.

The discovery of ER by Dr. Elwood Jensen exactly 60 years ago has not only led to the birth of a whole new vital nuclear receptor research field but also made a rapid, direct and lasting impact on the treatment and prevention of breast cancer. Since that landmark discovery, tremendous progress has been made in our understanding of the molecular functions of ER and development of targeted therapies against ER pathways for breast cancer treatment. However, there is currently no book available addressing these discoveries and recent advancement in a historical and systematic fashion. This book is intended to provide comprehensive, most up-to-date information on the history and recent advancement of ER and breast cancer by world renowned leaders in the field. These chapters include the history of the discovery of ER; physiological and pathological roles of ER; recent discovery of ER cistrome, transcriptome and its regulation of noncoding RNAs such as microRNAs and enhancer RNAs in breast cancer; development and clinical practices of the first targeted therapy Tamoxifen and other antiestrogens for breast cancer treatment; structural basis of ER and antiestrogen actions; molecular insights into endocrine resistance; the role of ER mutants, ER-beta and environmental estrogens in breast cancer; and emerging state-of-the-art therapeutic approaches currently in development to overcome treatment resistance and future perspectives. The book will provide undergraduate and graduate students, basic scientists and clinical cancer researchers, residents, fellows, as well as clinicians, oncology educators and the general public a thorough and authoritative review of these exciting topics.

The 4th International Symposium on Women's Health and Menopause, organized by the Giovanni Lorenzini Medical Foundation (Milan, Italy and Houston, Texas) focused on the new strategies to improve the quality of life of post-menopausal women. This volume illustrates the findings of this conference and includes information on the age-related degenerative processes occurring after menopause including cardiovascular disease, cancer, fractures and dementia.

Gynecologic cancer includes cancer of the female lower genital tract: vagina, vulva, cervix, endometrium, uterus, and ovaries.

Gynecologic Cancer is the fourth volume in the M.D. Anderson Cancer Care Series, featuring the current standard approach to gynecologic cancer care from the experts at M.D. Anderson Cancer Center.

Designed for the practicing oncologist, this clinical guidebook allows for quick, authoritative access to the latest and best multimodality therapies. Topics covered in this volume include primary prevention and early detection, preinvasive diseases of female lower genital tract, pathology and imaging of gynecologica malignancies, treatment of vaginal, cervical, endometrial, uterine cancers. Discussions also address fertility-sparing options for treatment of women with gynecologica cancers as well as sexuality in women with gyn malignancies. Each of the 20 chapters ends with an up-to-date list of suggested readings, as well as "key practice points" highlighting the most principles and practices of each chapter for at-a-glance reference. More than 80 illustrations complement the text. This thorough, practical volume is the essential clinical guide for the oncologists, surgeons, and all physicians involved in the care of patients with gynecologic cancer.

In January 1979, Robert Edwards and Patrick Steptoe delivered a lecture detailing the ten-year clinical and scientific research programme that led to the birth of Louise Brown, the first baby born utilising IVF. This thoroughly-researched book provides both a full annotated transcript of the lecture as well as recorded reminiscences from those who attended, detailing the contemporary understandings of the event. An essay on the lecture's historical context adds fresh insight into the biographies of Edwards and Steptoe and highlights sources from print and broadcast media that have received scant attention in earlier publications. Current and future implications of the advances in IVF since the first procedure are also explored, examining future medical and scientific possibilities as well as ethical issues that may arise. A foreword by Louise Brown herself places this remarkable leap of science in a personal context, one that so many families have since experienced themselves.

The ERAS (R) Society Handbook for Obstetrics & Gynecology covers all aspects of enhanced recovery care for disciplines of general gynecology, gynecologic oncology, urogynecology and obstetrical surgery. Written by renowned experts in the field, chapters discuss foundational knowledge on ERAS and provide specific worked examples, ERAS order sets, and practical implementation tools. This book is an indispensable resource to researchers interested in ERAS, but it is also ideal for anesthesiologists, gynecologists and obstetricians interested in initiating an ERAS program. Enhanced Recovery After Surgery (ERAS) is a global surgical quality improvement initiative that originated in colorectal surgery and has now spread to numerous other disciplines, including gynecology (benign and malignant) and obstetrics (caesarean delivery). ERAS is associated with improvements in clinical outcomes (reduction in length of hospital stay, complications, readmissions), cost savings for the healthcare system, and patient satisfaction, hence the addition of this comprehensive resource on the topics is a welcomed addition to the available literature.

Bei der Bluttransfusion handelt es sich um die Transplantation eines fremden flussigen Organs. Blutkomponenten und Plasmaderivate sind dabei verschreibungspflichtige Arzneimittel und durfen nur auf arztliche Anordnung abgegeben werden. Von dem am Patienten tatigen Arzt werden damit grundlegende klinisch-transfusionsmedizinische Kenntnisse fur den differenzierten Umgang mit Blutkomponenten und Plasmaderivaten gefordert. Das vorliegende Werk gibt diese Hilfestellung und vermittelt Basiswissen zu Blutprodukten und Transfusionen fur Nicht-Transfusionsmediziner. Es beschreibt u.a. die Risiken von Bluttransfusionen, die Grundlagen der Blutgruppenserologie und die Zusammensetzung von Blut und Blutprodukten sowie das Management bei Transfusionszwischenfallen; es geht auf das aktuelle Transfusionsgesetz ein und die Richtlinien zur Bluttransfusion sowie auf die Verordnung und Gabe von Blut und Blutprodukten. Das Werk ist praxisnah und ubersichtlich gestaltet mit vielen konkreten Tipps, Flussdiagrammen und Tabellen. Die 2. Auflage erscheint komplett aktualisiert erweitert, u.a. zu juristischen und arzneimittelrechtlichen Aspekten autologer Transfusionsverfahren und zum Effektivitatsvergleich autologer Verfahren wie Eigenblutspende versus Hamodilution versus maschinelle Autotransfusion. Das Werk richtet sich an klinisch tatige AErzte aller Fachdisziplinen, die keine ausgewiesenen Transfusionsmediziner sind.

Part of the renowned Donald School series, this book is a comprehensive guide to the diagnosis and management of reproductive and gynaecological endocrinology disorders. The book begins with an overview of ovulation and investigation and causes of female infertility including anovulation, tubal block, endometriosis and congenital uterine anomalies. The following chapters discuss ovarian stimulation and assisted reproductive techniques. The second half of the book covers causes and management of male infertility, and concludes with chapters on recurrent miscarriage, gamete banking, and assessment of early pregnancy. Authored by recognised experts in the field, the text is further enhanced by clinical photographs, illustrations, tables and flowcharts. Key points Comprehensive guide to diagnosis and management of reproductive and gynaecological endocrinology disorders Part of renowned Donald School series Covers investigation, causes and management of both female and male infertility Authored by recognised experts in the field

The second edition of this comprehensive reference provides practitioners with the latest advances in the use of ultrasound for diagnosis and management of subfertility. Divided into thirteen chapters, the book begins with an introduction to the principles and applications of ultrasound, and examination techniques and in pelvic assessment. The next sections cover the use of ultrasound for the diagnosis of different gynaecological conditions that may affect fertility, followed by ultrasound-guided procedures in assisted reproduction and potential complications. The text concludes with chapters on ultrasound in male infertility, and three-dimensional ultrasound in subfertility. Edited by recognised experts in the field, the text is further enhanced by more than 400 ultrasound images and is accompanied by an interactive DVD ROM providing video clips for each clinical scenario described in the book. Key points Second edition presenting latest advances in use of ultrasound in subfertility Includes DVD ROM of video clips demonstrating clinical scenarios Internationally recognised editor team Previous edition (9789351520108) published in 2014

Pelvic Organ Prolapse, or POP, is a little talked about female health issue that half of all childbearing women will experience late in life. There are more than 300,000 surgeries for POP annually. Due to various causes such as menopause, estrogen loss, genetics, childbirth or heavy lifting, a woman's pelvic organs can shift or drop. This can lead to POP symptoms, including some painful and embarrassing ones, as well as impacting a woman's sexuality. The condition has probably always existed, but has received little press or public acknowledgement so women could learn about the condition and treatment options. This book on POP fills an unfortunate void in women's health awareness. Sherrie Palm writes about her own personal experiences in Pelvic Organ Prolapse: The Silent Epidemic. She had never heard about the condition until she needed surgery for it. Palm explores the subject from all angles, providing the information women need to recognize the symptoms of POP and to become advocates for their own health. Pelvic Organ Prolapse: The Silent Epidemic named the winner for Women's Health in the USA Book News National "BEST BOOKS 2009" Awards. http://www.usabooknews.com/2009bestbooksawards. html More information about Sherrie Palm, and how she is creating awareness for this women's health issue can be found on her website: http://sherriepalm.com/home About the Author: First-time author Sherrie Palm is a retired business owner. She lives in Wisconsin with her significant other; she has four children and seven grandchildren. Palm plans to conduct educational seminars on POP. She is also actively involved with the local Special Olympics and will donate a portion of the book's proceeds to the group.

This book is a practical guide to the latest laparoscopic hysterectomy techniques for practising gynaecologists. Divided into four sections, the book begins with detail on preparing the operating theatre covering patient selection, theatre set up, patient positioning, instrumentation, and anaesthetic considerations. The next chapters discuss preparation for surgery, followed by step by step procedural instruction. The final section explains postoperative care. Authored by recognised experts in the field, this concise reference is enhanced by clinical photographs and figures. The accompanying DVD ROM features 16 videos covering all aspects of laparoscopic hysterectomy, also highlighting key points from the text. Key points Practical guide to laparoscopic hysterectomy procedures Provides step by step guidance from pre-surgical preparation, to operative techniques and postoperative care Includes DVD ROM demonstrating all aspects of laparoscopic hysterectomy Features clinical photographs and figures to enhance learning

This book is a comprehensive guide to the assessment and management of high risk pregnancy. Divided into eleven sections, the text begins with discussion on antenatal care, nutrition, genetic screening and ultrasonography-guided interventions in pregnancy. The following sections cover different factors that cause a pregnancy to be high risk including haematological disorders, early pregnancy complications, medical disorders such as gestational diabetes and cardiac disease, obstetric complications such as eclampsia and preterm labour, infections, foetal growth problems, and autoimmune diseases. The finals chapters discuss delivery complications and miscellaneous topics such as intrauterine foetal death, cerebrovascular accidents, ART pregnancies, and medicolegal aspects. The book is further enhanced by clinical photographs, diagrams and tables. Key points Comprehensive guide to management of high risk pregnancy Detailed discussion on screening and prevention of complications Presents recent advances in the field Highly illustrated with clinical photographs, diagrams and tables