This issue of Anesthesiology Clinics covers the latest updates in obstetric and gynecologic anesthesia written by the world-leading experts on the topic. Procedurally-focused articles cover best practices in chronic pain management, the role of magnesium in labor and delivery, advanced airway procedures, epidural analgesia, amniotic fluid embolism and more. Achieve the best outcomes and keep current on this area of anesthesia practice.

This issue of Sleep Medicine Clinics, Guest Edited by Frances Chung, MBBS FRCPC of the University of Toronto, will focus on Sleep and Neurorehabilitation. Article topics will include Sleep and Anesthesia; Neurobiology, Medicine, and Society; Upper airway, OSA and anesthesia; Positions, sleep and anesthesia; Sleep Deprivation, OSA and inflammation; Preoperative Screening for OSA; and PAP therapy for perioperative patients.

This issue of Anesthesiology Clinics covers the latest updates in cardiovascular anesthesia written by the world-leading experts on the topic. Procedurally-focused articles cover best practices in fluid and blood management, mechanical circulation support, anesthesia for robotic surgery, adult congenital heart surgery, transplantation and more. Achieve the best outcomes and keep current on this area of anesthesia practice.

Each volume in the 'Advances' series focuses on topics that are most critical and clinically relevant to improving patient care. Experts write articles, and give the practitioner and student fresh, thorough viewpoints on the topic's significance.

This issue of Anesthesiology Clinics covers the latest updates in trauma anesthesia written by the world-leading experts on the topic. Procedurally-focused articles cover best practices in video-assisted intubation devices, coagulation and hemorrhagic shock, homoestatis control, multiple casualties, massive bleeding and more. Achieve the best outcomes and keep current on this area of anesthesia practice.

This issue of Anesthesiology Clinics provides essential updates in neurosurgical anesthesia. Topics include anesthesia for endovascular neurosurgery; interventional neuroradiology; neuroimaging; anesthetic management of patients with acute stroke; perioperative management of pediatric patients; anesthetic neurotoxicity; airway management in neuroanesthesiology; anesthetic considerations for awake craniotomy for epilepsy; perioperative uses of trans cranial perfusion monitoring; monitoring and introaoperative management of elevated ICP and decompressive craniectomy; electrophysiologic monitoring in neurosurgery; traumatic brain injury; perioperative pain management in the neurosurgical patient; controversies in neurosciences critical care; sleep and mechanisms of anesthesia; and impacts on outcome after neuroanesthesia.

This issue of Anesthesiology Clinics covers essential topics in the post anesthesia care unit. Management of pain, delirium, acute renal failure, arrhythmias, and several post anesthesia complications are covered. Both adult and pediatric issues are addressed.

This issue of Anesthesiology Clinics covers the latest updates in thoracic anesthesia written by the world-leading experts on the topic. Procedurally-focused articles cover best practices in anesthestic management of one-lung ventilation, airway stenting, esophagectomy, mediastinal biopsies, postthoracotomy atrial fibrillation, and more. Achieve the best outcomes and reduce risks and complications in your thoracic anesthesia practice.

This issue of Anesthesiology Clinics brings the reader up to date on the most important advances in surgical palliative care for anesthesiology intensivists. Topics covered include recent trends and developments, palliative care of patients on high doses of narcotics, trauma in the surgical ICU, care of family in the surgical ICU, communication skills in palliative surgery, surgical palliative care in Haiti, and much more.

This cutting-edge issue of Anesthesiology Clinics is divided into two sections.? The first covers topics in perioperative clinical information systems (IS), including the following.? The anatomy of an anesthesia information management system; vendor and market landscape; impact of lexicons on adoption of an IS; clinical research using an IS, real-time alerts and reminders using an IS; shortcomings and challenges of IS adoption; creating a real return-on-investment for IS implementation (life after HITECH); Quality improvement using automated data sources and reporting; and opportunities and challenges of implementing an enterprise IS in the OR.? Section 2 is devoted to computers and covers the following topics.? Advanced integrated real-time clinical displays; enhancing point-of-care vigilance using computers; and computers in perioperative simulation and education.

In this issue of Anesthesiology Clinics, Guest Editors Pratik Panharipande and Wesley Ely look at modern sedation techniques in the critically ill. Topics include pharmacology of commonly used analgesics and sedatives in the ICU (including benzodiazepines, propofol, and opioids); pharmacology of sedative-analgesic agents (including dexmedetomidine, remifentanil, ketamine, volatile anesthetics, and the role of peripheral mu antagonists); lessons learned from international surveys of current sedation practices; protocolized and target-based sedation and analgesia in the ICU; sedation and weaning from mechanical ventilation, linking spontaneous awakening trials and spontaneous breathing trials to improve patient outcomes; altering ICU sedation paradigms to improve patient outcomes; sedation and sleep disturbances; sedation and immunomodulation; pharmacoeconomics of sedation; prevention and treatment of adult and pediatric delirium; and cognitive functioning, mental health and quality of life in ICU survivors.

This issue brings the anesthesiologist up to date on current essential topics in regional analgesia and acute pain management, including the latest state-of-the-art techniques and drugs.? Subjects covered include prevention and treatment of local anesthetic systemic and neurotoxicity; complications of RA and pain management (medicolegal issues including anticoagulation, infection, etc.); assessment and treatment of post block neurologic injury (history, physical, investigations, EMG, NCS); new ultrasound guided techniques for peripheral nerve blocks and evidence based outcome review; emerging techniques and drugs for neuraxial and paravertebral blocks; local infiltration analgesia (for a variety of surgical procedures, wound infusions, infusion devices); continuous PNB in hospital and at home; recent advances in multimodal analgesia (new drugs & strategies, such as capsaisin, long acting opioid and local anesthetics); challenges in acute pain management (including the opioid tolerant patient, patients with comorbidities such as MS, DM and renal failure); economics and practice management issues associated with acute pain management; pediatric pain management; new concepts of acute pain management (including strategies to prevent chronic pain, opioid induced hyperalgesia, and more).

The most engagingly written, clinically relevant overview of the practice of anesthesiology Morgan & Mikhail's Clinical Anesthesiology, Seventh Edition is an essential resource for all anesthesia students and practitioners. Hailed as the best primer on the topic, this trusted classic delivers comprehensive coverage of the field's must-know basic science and clinical topics in a clear, easy-to-understand presentation. The text is also ideal for coursework, review, or as a clinical refresher. Key features that make it easier to understand complex topics: Rich full-color art work combined with a modern, user-friendly design make information easy to find and remember The perfect distillation of essential information: succinct without sacrificing important details Case discussions promote application of concepts in real-world clinical practice Key Concepts at the beginning of each chapter identify important issues and facts Numerous tables and figures encapsulate important information and facilitate recall Up-to-date discussion of all relevant areas of anesthesiology, including equipment and monitors, pharmacology, pathophysiology, regional anesthesia, pain management, and critical care URLs for societies, guidelines, and practice advisories

Ongoing improvement in the quality of patient care is essential to all anesthesia practices. This issue of Anesthesiology Clinics provides solid foundation and guidance in how to improve outcomes, as it covers the following topics. An overview of QI structures and initiatives is presented, focusing on the relevance to anesthesiology. A practical guide on how to implement a QI program is provided. Quality measurement approaches and issues, including the use of databases and risk adjustment are also examined. How to use simulation and other cutting-edge technology to improve quality in the OR is provided. Issues in multidisciplinary education and enhanced communication are explored. Recommendations for fostering a culture of safety are provided. How real-time support and decision-making can improve performance on quality process measures are examined. Clinical topics including bariatrics, geriatrics and decreasing perioperative delirium, and pain management are covered, as well as issues about end-of-life care.

This book is a comprehensive guide to clinical anaesthesia for practitioners and trainees. Divided into eleven sections, the text begins with a general overview, followed by discussion on anaesthesia delivery systems, monitoring, and equipment. A complete section is dedicated to different drugs used in anaesthesia. The next section covers anaesthesia for different types of surgeries in various body systems. The remaining chapters detail more subspecialty-specific anaesthesia including cardiac, obstetric, neuro, paediatric, transplant, and regional. The book concludes with a section on postoperative care. Authored by highly experienced experts in the field, the text is further enhanced by illustrations and figures to assist learning. Key points Comprehensive guide to clinical anaesthesia for practitioners and trainees Covers numerous types of anaesthesia for different surgeries and body systems Includes sections on pharmacology and postoperative care Highly experienced, expert author team

Foreword by Walter J. Freeman.

The induction of unconsciousness using anesthetic agents demonstrates that the cerebral cortex can operate in two very different behavioral modes: alert and responsive vs. unaware and quiescent. But the states of wakefulness and sleep are not single-neuron properties---they emerge as bulk properties of cooperating populations of neurons, with the switchover between states being similar to the physical change of phase observed when water freezes or ice melts. Some brain-state transitions, such as sleep cycling, anesthetic induction, epileptic seizure, are obvious and detected readily with a few EEG electrodes; others, such as the emergence of gamma rhythms during cognition, or the ultra-slow BOLD rhythms of relaxed free-association, are much more subtle. The unifying theme of this book is the notion that all of these bulk changes in brain behavior can be treated as phase transitions between distinct brain states.

Modeling Phase Transitions in the Brain contains chapter contributions from leading researchers who apply state-space methods, network models, and biophysically-motivated continuum approaches to investigate a range of neuroscientifically relevant problems that include analysis of nonstationary EEG time-series; network topologies that limit epileptic spreading; saddle--node bifurcations for anesthesia, sleep-cycling, and the wake--sleep switch; prediction of dynamical and noise-induced spatiotemporal instabilities underlying BOLD, alpha-, and gamma-band Hopf oscillations, gap-junction-moderated Turing structures, and Hopf-Turing interactions leading to cortical waves.

This issue brings the anesthesiologist up to date on current essential topics in anesthesia for otolaryngologic surgery, covering the newest cutting-edge procedures.? Topics covered include functional vocal cord surgery; functional endoscopic sinus surgery & skull base surgery; pediatric and adult laryngeal/tracheal surgery; jet ventilation; middle ear; neuromonitoring; transoral robotic surgery; lasur surgery and fire hazards in ENT; office-based procedures; applications of ultrasound in ENT (nerve blocks & airway assessment); LMAs for surgery procedures in head and neck; and anesthesia, OSA, and upper airway collapsibility.

One of the anesthesiologist's greatest challenges is managing high-risk patients with acute or severe conditions.? This issue brings the anesthesiologist up to date on the most important and latest approaches to management of the sickest of patients.? Topics covered include managing the patient with sepsis or septic shock; anesthetic considerations for patients in respiratory failure; anesthetic concerns in patients presenting with renal failure; perioperative management of patients with liver failure; management of acute coronary syndrome in the OR; intraoperative concerns in patients presenting with sever aortic stenosis, aortic insufficiency, mitral regurgitation, or mitral stenosis; intraoperative management of patients with cardiac tamponade; anesthetic concerns in trauma victims requiring operative intervention; patients presenting with acute toxin indigestion; anesthetic concerns in patients with known neurologic insufficiency; management of endocrine insufficiency in the OR; and management of patients with mediastinal mass or tracheal stenosis.

Guest Editor Dane Nichols, MD, has assembled a panel of experts focusing on Hemodynamic Support in Septic Shock. Topics include: Oxygen Delivery and Consumption: A Macro-Circulatory Perspective; Mean Arterial Pressure: Therapeutic Goals and Pharmacologic Support, Mechanisms; Detection and Potential Management of Microcirculatory Disturbances; Detection of Hypoxia at the Cellular Level; Type A & B Lactic Acidosis: Recognition, Kinetics, and Associated Prognosis; Venous blood gases: What Can They Tell Us About the State of the Circulation; Noninvasive Assessment of Cardiac Preload and Performance through CO2 Rebreathing/ETCO2 Monitoring.

This issue of Anesthesiology Clinics prepares the anesthesiologist for the most challenging problems he will face with geriatric patients. Topics covered include delirium, postoperative cognitive dysfunction, fat embolism during hip replacement, Parkinson's disease and deep brain stimulator placement, diastolic dysfunction, atrial fibrillation, delayed arousal, severe atrial stenosis, multiple medications, informed consent and the ethical management of the older patient, dead bowel, acute perioperative beta-blockade in the older patient, urinary retention, and anesthetic care for patients with skin breakdown.

This issue of Anesthesiology Clinics covers the most cutting-edge topics in pediatric anesthesia that every practitioner must know to stay current in this changing field. Topics covered include new devices for difficult pediatric airway, the use of ultrasound in pediatric regional anesthesia, new concepts in treatment of pediatric traumatic brain injury, acute pain management, neurotoxicity of anesthetics in the developing brain, current thought on intraoperative awareness in children, current concepts on managing sepsis in children, the fontan patient, sedating the child with congenital heart disease, management of children with hemoglobinopathies, and current strategies for blood conservation in pediatric anesthesia.

This issue brings together leading specialists from diverse fields including multiple subspecialties of anesthesiology, as well as surgery, cardiology, oncology, neurology, hospital medicine, endocrinology, and others. A multidisciplinary approach is essential to patient safety and optimal outcomes, so this valuable and unique monograph brings the anesthesiologist up to date on current integrated methods of preoperative assessment, consultation, and patient preparation for surgery. Article topics include preoperative evaluation and prep of the patient for cardiac surgery; noncardiac surgery in the patient with heart disease; identification and evaluation of the patient with lung disease; surgery on the patient with endocrine dysfunction; obesity, metabolic syndrome, and the surgical patient; surgery in a patient with liver disease; surgery in the patient with renal dysfunction; anemia in the preoperative patient; perioperative anticoagulant management; preop prep of the surgical patient with neurologic disease; and emergency and urgent surgery.

Hemoglobin-based Oxygen Carriers is an exciting and evolving alternative to blood transfusion. This issue explores its potential with topics on: "HBOCs from Human or Bovine Hemoglobin," "Comparison of HBOCs to Stored Human Red Blood Cells," "HBOCs and Tissue Oxygenation," "HBOCs: Role in surgery, resuscitation or hemorrhagic shock?" and more!

In this issue, Guest Editors Pratik Panharipande and Wesley Ely look at modern Sedation techniques in the critically ill. Topics include: "Pharmacology of commonly used sedatives and analgesics in the ICU," "Pharmacology of newer agents for sedation and analgesia in the critically ill," "Current sedation practices: lessons learned from recent international surveys," "Sedation and Immunomodulation," "Sedation and sleep disturbances in the ICU," and more!