Endocrinology is a rapidly developing field with many new concepts. In addition, many new hormones have been described since 1960. The structural analysis and synthesis of several intestinal hormones such as gastrin, secretin, glucagon and cholecystokinin have been achieved. Several hypothalamic hormones controlling pituitary function have been identified and in certain cases synthesized. The existence of hormonal peptides se creted from ectopic sites has been recognized. The development of new techniques of hormone assay has stimulated studies on the effects of anesthetics on the endocrine system. Although the endocrine response to anesthesia is less than its response to major surgical procedures, the effects of anesthesia on metabolism and on the autonomie nervous system are substantial. The primary purpose of this book is to increase the safety of patients undergoing anesthesia by making available the latest developments in this field. The major subjects examined in the book are endocrine responses to anesthesia and surgery, the effects of endocrine disease on anesthesia and sur gery, and pre-operative and post-operative management of patients with endocrine disease. The book is designed for students, residents and practicing physicians in the field of anesthesia and surgery. Many tables and figures are empIoyed to improve the presentation, particuIarly those relating to pharmacology and to the practical aspects of therapy."

Part of the highly popular Practical Approach to Anesthesia series, this new edition combines the comprehensive depth of a textbook and the user-friendly features of a practical handbook. Focusing on clinical issues in pediatric anesthesia, it contains the in-depth information you need for daily practice and study, presented in a concise, bulleted format for quick reference. With its emphasis on developmental aspects of pediatric anesthesia, numerous illustrations and tables, and methodical approach to decision making, this updated reference is an invaluable resource for anyone involved with anesthesia of children.Key Features Features new chapters on vascular biology and vascular anomalies, healing and recovery in pediatric surgery, and training and education in pediatric anesthesia. All existing chapters have been fully updated to keep you up to date. Covers key issues of growth and development – anatomic, physiologic, and pharmacologic – that form the basis for a better understanding of pediatric anesthesia. Discusses the approach to the pediatric patient, clinical and operational aspects of pediatric anesthesia, anesthetic management of normalities and abnormalities of each organ system, and special situations such as fetal surgery, anesthesia outside the operating room, and trauma. Provides a clear understanding of anomalies, embryology, anatomy, and surgery so that you’re well prepared to choose the best induction, maintenance, and emergence techniques, as well as make informed monitoring and equipment decisions. Presents information in a bulleted, outline format for easy reference and review. Now with the print edition, enjoy the bundled interactive eBook edition, which can be downloaded to your tablet and smartphone or accessed online and includes features like: Complete content with enhanced navigation Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web Cross-linked pages, references, and more for easy navigation Highlighting tool for easier reference of key content throughout the text Ability to take and share notes with friends and colleagues Quick reference tabbing to save your favorite content for future use

During the recent years the basic sciences have become a major stimulant toward progress in medicine. Technique itself plays a vital role in today's medicine. With the increasing complexity of equipment, hazards related to malfunction and misuse have grown proportionally. The machine used with insufficient knowledge could become a deadly instrument. The basic elements of the anaesthesia machine, their design, and the physical basis for their function is discussed in the monography by the engineer, Peter 1. Schreiber. His knowledge is based upon fifteen years experience in the medical equipment industry in both Germany and the United States as well as his teaching activities in various medical schools. Detailed knowledge of equipment and the related physical laws has gained increasing importance in the training of anaesthesiologists. Fundamental knowledge of the design, function, and performance of an anaesthesia machine is the key to the art of its use. Mainz/Rhine, December 1971 Dr. RUDOLF FREY, F.F.A.R.C.S. Professor of Anaesthesiology Johannes Gutenberg-University Acknowledgements I wish to thank Dr. STANLEY W. WEITZNER, Professor, Department of Anesthesiology, State University of New York, Downstate Medical Center, for his helpful criticism of the chapter dealing with the per formance and classification of ventilators. I also want to thank Mr. DAVID F. BOERNER for his assistance in rewording the language and physiochemical terminology of the manu script."

During the First European Congress of Anesthesiology, held in Vienna, Austria, in September, 1962, panel discussions on nineteen different subjects were held, each lasting approxi mately three hours. One, concerning Controversial Aspects of Resuscitation, was later edited by its chairman, PETER SAFAR, and published in 1963. At the request of the publisher, the discussion on hypnosis has been edited in a similar manner. The participants in the discussion on Hypnosis in Anes thesiology had agreed, prior to the meeting, on a list of questions to be debated, and Dr. STOKVIS' introductory statement on the nature of hypnosis was circulated among them in appropriate translations in order to give the debate a starting point. It had also been agreed that no formal papers should be read after this introduction, and that the participants should use at will the German, English or French language. Following each contribution it was the chairman's task to give a brief summary in the two other languages. Discussion was therefore somewhat slowed down and occasionally rendered difficult by misunderstandings or the omission of details. Drs. GUEGUEN, MOSCONI, and VOLGYESI, who were not able. to attend, had sent written contributions which the chairman presented briefly during the discussion. The present text has been worked out of the tape recording of the discussion and the chairman's correspondence with the panelists some time after the meeting. Whenever the original contributions were in French or German, the English translation has been the chairman's."

The First European Congress of Anesthesiology in Vienna, Austria in September, 1962 presented 19 Symposium discussions, each lasting approximately 3 hours. Unlike most of these panels, the one on Resuscitation was a free discussion on controversial topics, without presentation of formal papers. In spite of the spontaneity of the unrehearsed questions and ans wers, the participants feit that an edited version of this Symposium should be published. The reasons for publication included the inter national character of the group of participants and the recent general interest in respiratory and circulatory resuscitation. A presentation of accepted resuscitation techniques was omitted, because of lack of time and because the Symposium was held pri marily for trained anesthesiologists, most of whom have first-hand experience with resuscitation and should be familiar with the accepted modern methods. Only controversial topics, which seemed to be of interest to those with personal experience in the application and the research of resuscitation, were included."

Ultrasound has revolutionized the practice of regional anesthesia, yet there remains a paucity of good resources on ultrasound-guided regional anesthesia in children. This book offers a much-needed practical guide to all the major ultrasound-guided blocks in pediatric patients, including neuraxial, truncal, upper and lower limb blocks. The core principles of good clinical practice in regional anesthesia are described and discussed, including the pharmacology of local anesthetics in children, the performance of regional anesthesia, the management of complications, and the clinical anatomy of each block. Every block chapter provides both a 'how to' section and also a comprehensive literature review, with an up-to-date and relevant bibliography for reference and further reading. Chapters are illustrated with unique anatomical images and detailed descriptions. Both trainee and experienced anesthesiologists will find this an essential resource for the safe and effective performance of modern regional anesthesia in children.

This book is a practical revision aid for postgraduates preparing for Final FRCA (Fellowship of the Royal College of Anaesthetists) written examinations. Presented in the style of the newly introduced CRQ (Constructed Response Questions) format, the book features five complete papers, each containing twelve questions. Topics cover the entire examination syllabus. Detailed answers are given for every question, as well as comprehensive references for further reading. Key points Practical revision aid for candidates preparing for Final FRCA examinations Presented in the style of the new CRQ format Includes five papers each containing twelve questions with detailed answers Topics cover the complete exam syllabus

This book aims to provide an overview of the basics of anesthesia for neurotrauma. It showcases how management of different neurotrauma cases may differ, especially those involving spine and or polytrauma. It provides quick and easy access to understand anesthesia for neurotrauma.

A key requirement of the primary and final FRCA examinations is a sound understanding of the basic sciences behind anaesthetic practice. It is important to be able to describe these principles clearly, particularly in the viva section of the examinations. Featuring several new topics, this fully updated new edition of this best-selling book provides all the important graphs, definitions and equations which may be covered in the examinations, together with clear and concise explanations of how to present them to the examiner and why they are important. Packed full of precise, clear diagrams with well structured explanations, and with all key definitions, derivations and statistics, this is an essential study aid for all FRCA examination candidates.

Welche Studienergebnisse entsprechen der besten wissenschaftlichen Evidenz? Erfahrene Herausgeber und Autoren stellen hier aktuelle Studienergebnisse nach EBM-Kriterien zusammen. Bereits nach kurzer Zeit in 2., komplett aktualisierter Auflage mit systematischer Gliederung der Inhalte nach den Bereichen Anasthesie und Intensivmedizin. Um viele praxisrelevante Themen erweitert u.a.: der kardiale Risikopatient, Transfusions-und Gerinnungsmanagement, Analgosedierung und Blutzuckermanagement auf der Intensivstation, intensivmedizinische Therapie der Pneumonie, COPD und des akuten Nierenversagens. Ein Werk, das arztliche Entscheidungen auf eine wissenschaftliche Basis stellt und aktuelle Studienergebnisse in den Klinikalltag integriert.

The fully updated Crisis Management in Anesthesiology continues to provide updated insights on the latest theories, principles, and practices in anesthesiology. From anesthesiologists and nurse anesthetists to emergency physicians and residents, this medical reference book will effectively prepare you to handle any critical incident during anesthesia. "A comprehensive discussion of the latest theories, principles and practices for CRM in perioperative practice and will be a useful resource for anaesthetists of all grades and levels of experience" Reviewed by British Journal of Anaesthesia, Jun 2015 "...this book contains essential information that all anesthesiologists should know or readily be able to easily reference..." Reviewed by Jane Torrie, Oct 2015 "Every anesthesia provider needs to study, not just read, this new edition, even if you read the first edition. Also, distilled instructions of key elements of the cases covered in this book need to be included in manuals made available for emergencies (although that, too, needs further study on how best to use them). If I were your patient, I would ask if you had studied these principles. If you hadn't, I might ask for another health care provider into whose hands I would want to entrust my life." Foreword by: Jeffrey B. Cooper, PhD Harvard Medical School, Boston, Massachusetts, July 2015 Identify and respond to a broad range of life-threatening situations with the updated Catalog of Critical Incidents, which outlines what may happen during surgery and details the steps necessary to respond to and resolve the crisis. React quickly to a range of potential threats with an added emphasis on simulation of managing critical incidents. Useful review for all anesthesia professionals of the core knowledge of diagnosis and management of many critical events. Explore new topics in the ever-expanding anesthesia practice environment with a detailed chapter on debriefing. Expert Consult eBook version included with purchase.

The increased complexity of spinal surgical procedures in recent years has required more sophisticated anesthetic management of patients undergoing these procedures. Spine surgery anesthesia is now recognized as a distinct sub-specialty, increasingly undertaken by general anesthesiologists as well as neuroanesthesiologists. Anesthesia for Spine Surgery describes the anesthetic management and surgical procedures at every vertebral level in both adult and pediatric patients. The most important related considerations are covered, including: * Postoperative pain management * One lung ventilation during anterior thoracic spine surgery * Intraoperative neuromonitoring * Fluid management Additional chapters review the radiological features of normal and abnormal spines, common complications of spine surgery and ASA closed claims relating to spine surgery anesthesia. Written by highly experienced neuroanesthesiologists and spine surgeons, Anesthesia for Spine Surgery is essential reading for trainee and practising anesthesiologists, neuroanesthesiologists and spine surgeons.

Obesity is a global public health issue; significant numbers of the world's population are overweight, growing numbers are obese, and many are morbidly obese. As obesity is associated with a range of co-morbidities (namely cardiovascular disease, diabetes, cancer, depression, and sleep apnoea), it presents a daunting peri-operative challenge to the anaesthetist. The increasing size and weight of patients presenting for surgery involves multiple issues from starting intravenous lines through to intubation and ventilation challenges. The Oxford Textbook of Anaesthesia for the Obese Patient is a highly authoritative, evidence-based account of the principles and clinical practice within the field. Across 36 chapters, this resource provides comprehensive coverage of all aspects of the subject including physiological and pharmacological modifications in the obese patient, bariatric and non-bariatric surgery, specific clinical issues such as fluid management and tissue oxygenation, as well as challenges arising from obesity in the setting of paediatrics, obstetrics, intensive care and trauma. Written and edited by experts in the field, this resource is the definitive guide to clinical management of the obese patient, exploring various international approaches to practice, with helpful case studies, and practical advice on common intra-operative challenges, and how to resolve them using evidence and best practice.

This pack brings together two essential texts on the clinical specialties, covering all core topics for a value-for-money price. Updated with the latest advice and clinical guidelines, packed full of high-quality illustrations, boxes, tables, and classifications, and with a brand new chapter on how to survive your junior doctor years and beyond, the Oxford Handbook of Clinical Specialties is ideal for both study and use at direct point of care. Each chapter is clear and concise and filled with medical gems, with features including ribbons to mark your most-used pages and mnemonics to help you memorize and retain key facts. With reassuring and friendly advice throughout, this is the ultimate guide and revision tool for every medical student and junior doctor for each clinical specialty placement. Accompanying this resource is the fourth edition of Oxford Assess and Progress: Clinical Specialties which features over 400 Single Best Answer questions that are mapped to the medical school curricula. Packed with questions written by experienced doctors in each specialty, and rooted in real-life clinical encounters, this revision tool is an authoritative guide for students. Further reading resources and cross-references to the Oxford Handbook of Clinical Specialties have been fully updated to expand your revision further on topics you find challenging.

Clinical Anaesthesia Lecture Notes provides a comprehensive introduction to the modern principles and practices of anaesthesia for medical students, trainee doctors, anaesthetic nurses and other health professionals working with anaesthetists. This fifth edition has been fully updated to reflect changes in clinical practice, guidelines, equipment and drugs. Key features include: A new chapter on the roles of the anaesthetist Increased coverage of the peri-operative management of the overweight and obese patient, as well as an introduction to the fundamental aspects of paediatric anaesthesia Coverage of recent developments within the specialty, including the rapidly growing recognition of the importance of non-technical skills (NTS), and the management of some of the most common peri-operative medical emergencies Links to further online resources A companion website at www.lecturenoteseries.com/anaesthesia featuring interactive true/false questions, SAQs, and a list of further reading and resources Full-colour diagrams, photographs, as well as learning objectives at the start of each chapter, support easy understanding of the knowledge and skills of anaesthesia, allowing confident transfer of information into clinical practice.

Pharmacology and physiology are the foundation of every anesthesia provider's training and clinical competency. Pharmacology and Physiology for Anesthesia: Foundations and Clinical Application, 2nd Edition, delivers the information you need in pharmacology, physiology, and molecular-cellular biology, keeping you current with contemporary training and practice. This thoroughly updated edition is your one-stop, comprehensive overview of physiology, and rational anesthetic drug selection and administration, perfect for study, review, and successful practice. Contains new chapters on Special Populations (anesthetic pharmacology in obesity, geriatrics, and pediatrics), Oral and Non-IV Opioids, Thermoregulation, Physiology and Pharmacology of Obstetric Anesthesia, Chemotherapeutic and Immunosuppresive Drugs, and Surgical Infection and Antimicrobial Drugs. Incorporates entirely new sections on Physics, Anatomy, and Imaging. Includes new information on consciousness and cognition, pharmacodynamics, the immune system, and anti-inflammatory drugs. Features user-friendly tables, figures, and algorithms (including 100 new illustrations), all presented in full color and designed to help explain complex concepts. Helps you understand the molecular mechanism of drug actions and identify key drug interactions that may complicate anesthesia with dedicated sections on these areas. Expert ConsultT eBook version included with purchase, which allows you to search all of the text, figures, and references from the book on a variety of devices

The perioperative care of individuals with neurologic compromise is critically important, yet it is only one dimension of the rich relationship between anaesthesiology and the neurosciences. The mechanism of everyday therapeutic interventions such as anaesthesia and analgesia is exciting neuroscience in its own right. At the new frontier of outcomes studies lies the question of how the perioperative period might impact the brain. For example, questions related to anaesthetic neurotoxicity, delirium, and cognitive dysfunction pose critical challenges for the field. The Oxford Textbook in Neuroscience and Anaesthesiology addresses the exciting field of neuroanaesthesiology in a new and stimulating way. In twenty eight chapters, the neuroscientific basis of anaesthesiology, the full spectrum of clinical neuroanaesthesia, and the care of neurologic patients undergoing non-neurologic surgery are explored in one comprehensive textbook for the first time. The first section considers the neural mechanisms of general anaesthetics, cerebral physiology, the neurobiology of pain, and more. The second section explores the care of patients with neurologic disease in the operating room or intensive care unit. These clinical chapters systematically treat the perioperative considerations of both brain and spine surgery, and provide introductions to neurocritical care and pediatric neuroanaesthesia. The final section outlines the care of neurologic patients undergoing non-neurologic surgery. It examines key connections of neurology and anaesthesiology, examining how conditions such as dementia, stroke, or epilepsy interface with the perioperative period. Each chapter has been carefully crafted to be concise yet highly informative, reflecting the cutting edge of neuroscience and neuroanaesthesiology. This international textbook gathers the best available expertise of authors and leaders worldwide. Includes access to online-only content, including more than 20 cases and more than 90 questions that can be used in presentations and teaching sessions. By activating your unique access code, you can access and use the material.

Another title in GMM's highly successful QBase series, this time focusing on the Primary FRCA (Fellowship of the Royal College of Anaesthetists) with sets of examination papers the candidate can use to revise and practice their MCQ technique. As always, the self-learning experience is greatly enhanced by the free CD-ROM containing the QBase examination software. This powerful program allows the user to sit the pre-set exams as printed in the book, or to create their own exams using questions drawn from the total pool available on the CD-ROM. The program can either generate these exams randomly (maintaining the same proportions of each subject as the 'pre-set' exams), or the user can select any number of questions in any subject area, to create their very own exam. However the user chooses to set an exam, they can then mark, analyse and store each attempt, and review and re-sit the same exam at a later date, comparing their scores with previous attempts. When re-sitting an exam, the user can also choose to 'shuffle' the question stems A-E, so that they cannot simply remember patterns of true and false answers. A final unique aspect of the program is that it allows the user to select how confident they are of their answer, and the program can then provide feedback on a user's 'guessing strategy'.

This second edition of Clinical Pediatric Anesthesia: A Case-Based Handbook offers a comprehensive review of the options, advantanges, and disadvantages of different aspects of the perioperative management of the pediatric patient, as well as examples of a wide range of relevant clinical scenarios. Chapters are organized into 15 sections and cover the field of pediatric anesthesiology with a point-of-care approach. Written by a team of over 50 Pediatric Anesthesiologists at tertiary children's hospitals, this highly accessible text provides readers with multiple approaches to the anesthetic care of the pediatric patient. Each chapter includes an introduction to the topic, followed by learning objectives, clinical vignettes, and a discussion section styled in a question-and-answer format, concluding with a summary of the highest-yield and most salient information. Chapters also provide annotated references and suggestions for further reading to facilitate in-depth study of topic. The variety of cases presented, along with the contributors' expertise, render valuable real-life clinical situations that promote critical thinking and evaluation necessary for all pediatric anesthesiology consultants.

As the practice of obstetric anesthesia becomes increasingly recognized as a major subspecialty of anesthesia, there is a growing interest from current practitioners to evolve their neuraxial, regional, and general anesthesia techniques and understanding of the latest evidence. Obstetric Anesthesia Practice is a timely update in the field, providing a concise, evidence-based, and richly illustrated book for students, trainees, and practicing clinicians. Comprehensive in scope, this book addresses the essential topics necessary for the practitioner to quickly assess the patient and risk stratify them, decide on the type of analgesic and anesthetic plan most appropriate as well as its feasibility and safety, provide expert consultation to the other members of the obstetric team, manage anesthesia care and complications, and arrange for advanced care if needed.

Written for anaesthesia trainees, this comprehensive text covers all the MCQ preparation required for both the Primary and Final FRCA exams. Broken down into five sections, there are 150 questions for each of the physics, pharmacology, anatomy, and physiology sections, and a fifth section of 400 questions covering clinical anaesthesia. The first four sections of 150 questions match the Primary exam and are laid out to follow its format. The fifth clinical section covers the entire clinical syllabus. The authors are educators in anaesthesia and surgery and their wealth of experience has been brought together in this text to benefit the next generation of anaesthetists. Covering the entire syllabus, with 1,000 expertly distributed questions, this is the most comprehensive text available for MCQ preparation for both parts of the FRCA.

Covering the most important topics in trauma anesthesia, this updated edition provides anesthesiology trainees and practitioners with a practical basis for managing trauma patients. Many recent advances in trauma care are identified, including paradigm shifts in the management of bleeding and coagulopathy, new neuromuscular blockade and anticoagulant reversal drugs, and updated clinical practice guidelines. This volume provides a concise, practical review of the essential elements in the care of the severely injured trauma patient, including emergency airway management, fluid and blood resuscitation, monitoring, coagulation therapy, regional and general anesthesia, and perioperative care. Edited by two of the most experienced trauma anesthesiologists in the United States, with chapters written by experts from leading US and Canadian trauma centers with the highest and most varied caseload of critically injured patients, Essentials of Trauma Anesthesia identifies new trends in surgery and anesthesiology practices that impact on the management of trauma patients.

This practical text offers a comprehensive guide to perioperative temperature management for anaesthetists, surgeons and nurses. The physiological basics of thermoregulation and heat exchange are covered, before the changes that occur during general and regional anaesthesia are outlined. The relevant adverse scenarios associated with perioperative hypothermia, including morbid cardiac events, impairment of coagulation, increased blood loss and surgical site infections are discussed, before the methods of measuring core temperature and the equipment and techniques to keep patients warm are described. Richly illustrated and clearly structured for quick reference, Perioperative Temperature Management is an essential daily resource to help ensure safe, effective practice.

The Structured Oral Examination can be the hardest component of the Primary FRCA examination to prepare for, but help is at hand. This book has been specifically designed to give realistic practice questions and to show you how to phrase and develop your answers. The questions included have been mapped to the FRCA examination curriculum and reflect both core and niche subject areas. Questions are presented as full mock examinations and also divided by section, enabling you to use the book in whichever way you find most effective. Complete scripted answers allow you to see how questions develop and help you to hone your technique. Handy hints and tips for exam preparation are included throughout the book, and a dedicated introduction section covers common pitfalls and how to avoid them. This is an invaluable preparation guide and sample question resource for trainees and trainers alike.