This new series, based on a bi-annual conference and its topics, represents a major contribution to the emerging science of cancer research and regenerative medicine. Each volume brings together some of the most pre-eminent scientists working on cancer biology, cancer treatment, cancer diagnosis, cancer prevention and regenerative medicine to share information on currently ongoing work which will help shape future therapies. These volumes are invaluable resources not only for already active researchers or clinicians but also for those entering these fields, plus those in industry. Tissue Engineering and Regenerative Medicine is a proceedings volume which reflects papers presented at the 3rd bi-annual Innovations in Regenerative Medicine and Cancer Research conference; taken with its companion volume Stem Cells: Biology and Engineering it provides a complete overview of the papers from that meeting of international experts.

This book summarizes the basics of actinobacteria, from microbiology to synthetic biology. It focuses on diversity, NRPS, sesquiterpenes, lantipeptide, bioinformatics apparatuses, cloning, CRISPR, reverse engineering, FDA supported medications, and marine actinobacteria. It also covers the latest trends in drug discovery from actinobacteria, and introduces several recently developed bioinformatics and synthetic biology tools to explore new antibiotics from actinobacteria. Many natural products such as polyketides, isoprenoids, phenazines, peptides, indolocarbarbazoles, sterols, and others have been isolated and characterized from actinobacteria. Some products are synthesized by the non-ribosomal peptide synthetases (NRPSs), polyketide synthases (PKSs), or other functional genes. Although genome sequencing has uncovered the differing qualities of these chemicals, recognizing new items and their biosynthetic pathways is still under examination. Cryptic metabolic pathways have been explored using molecular techniques or culture-dependent approaches. In recent years, researchers' primary interest is to identify the specific conditions or agents that wake the cryptic antibiotics. Several bioinformatics and synthetic biology tools were developed to explore new antibiotics from actinobacteria. The book comprises 14 chapters with different aspects of application and utilization of actinomycetes from the microbiology; systems biology, pharmacology of natural products, bioinformatics, actinomycete and its diversity, CRISPR, artificial Intelligence, synthetic biology, metabolic engineering, expressional studies, and biosynthetic gene clusters. The book delivers useful information on actinomyces to researchers, novices in genome designing, specialists, clinicians, policymakers, and professionals.

Carbon and Graphene Quantum Dots for Biomedical Applications provides a single point of reference for understanding the biomedical potential of quantum dots. The book covers the synthesis and properties of various carbon and graphene quantum dots, with advanced discussion on the challenges faced during synthesis according to type, structure, size, functionalization and composition. Key biomedical applications are described, including bioimaging, biosensing, antimicrobial and drug delivery. The benefits and issues of utilizing carbon and graphene quantum dots in biomedical applications are addressed in detail, evaluating vital aspects such as cytotoxicity, inhibition concentration and point-of-care-specific challenges. This book offers an exciting and thorough overview of this emerging area for academics and researchers in the fields of materials science, biomedical engineering, nanotechnology, and pharmaceutical science, as well as for R&D groups in biosensing and drug development.

Provides a contemporary view of the impact of climate change on cultivation of various fruit species. Offers modern approaches for mitigating the adverse impact of climate change on fruits cultivation. Describes case studies, empirical experiments and observations emphasizing the research progress of understanding and combating the impact of climate change on fruits production. Illustrates presented concepts with relevant figures and tabulated data.

Current environmental and energy concerns have led to lignin gaining increased attention in the last decade as a renewable biomass. Due to its structural and functional properties, such as antimicrobial behaviour, biodegradability, biocompatibility and ease of surface modifications, lignin-based materials have gained popularity in the biomedical field with applications ranging from tissue engineering scaffolds and wound dressing materials to drug delivery carriers. Using this book, the reader will learn about the chemistry of lignin, and the characterization, fabrication and properties of lignin-based composites with different matrices (thermosets, thermoplastics, elastomers etc.). In addition, the book illustrates how these materials are used in medical applications, covering drug delivery, wound dressing, tissue engineering, imaging, etc. Providing a neat overview of the current research for the biomaterials science community, this book is a one-stop resource for researchers and practitioners working on lignin-based biomaterials. For those active in the broader fields of materials science and biomedical engineering, this will be a useful reference and study aid.

Hydrogels are highly hydrated three dimensional networks with the ability to mimic the extracellular matrix of bodily tissues and have thus found application in a wide range of biomedical applications. Unique physiochemical properties such as biocompatibility, water permeability, stimuli responsiveness and self-healing characteristics make them especially useful for use as scaffolds and matrices drug delivery, tissue engineering/regeneration and sensing. Their weak and brittle nature, however, often limits their widespread application where improved mechanical strength is required. To resolve this problem, there has been a significant amount of research into the improvement of their mechanical properties. Among these efforts, versatile multicomponent hydrogels have received much attention as their physiochemical properties can be structurally engineered to provide a wide range of desired properties. These multicomponent formulations also allow for the combination of natural and synthetic polymers, which offers the scope to exploit the advantages of each component, with the synergistic effects resulting from mutual interactions. This book critically discusses the fundamental chemistry, synthesis, characterisation, physiochemical and biological properties of various types of multicomponent hydrogels. It reviews the different strategies employed in designing and synthesizing cutting-edge multicomponent hydrogels and their key applications in biomedical fields. The work is suitable for researchers working in the specific area of multicomponent hydrogels, and also more generally for those working in materials science, biomedical engineering, biomaterials science and tissue engineering.

This book is the first comprehensive compilation describing the botanical traits, genetic resources, whole genome sequencing, Mitochondrial genome, transcriptomes of different organs with developmental stages, transcription factors, delineating gene evolution of gene family in Bambusoideae, alternative splicing (AS) and polyadenylation, case studies for economically important traits such as internode length, shoot fast growing, flowering, ageing and stress-resistant genes and small RNAs-mediated gene regulation of moso bamboo flowering and other developmental stages. Applications of transcriptome and genome approaches in moso bamboo in general and the prospects of transgenic breeding and genome editing technologies in bamboo are also discussed. Altogether, the book comprises eleven chapters covered over 200 pages authored by the researchers involved in genomic science, molecular biology, and breeding. This book appeals to graduate students, post-graduate students, research scholars, researchers, and industry players in the field of plantation bamboo in general, bamboo processing and bamboo garden owner and fans of bamboo culture in particular.

Legumes include many very important crop plants that contribute very critical protein to the diets of both humans and animals around the world. Their unique ability to fix atmospheric nitrogen in association with Rhizobia enriches soil fertility, and establishes the importance of their niche in agriculture. Divided into two volumes, this work presents an up-to-date analysis of in vitro and recombinant DNA technologies for the improvement of grain, forage and tree legumes.
Volume 10A examines the current status and future prospects of challenges of the following: in vitro morphogenesis; biotic and abiotic stress tolerance; genomics; nitrogen fixation and utilization; nutritional improvement, and biodiversity of wild and tribal legumes.
Volume 10B presents the current state and future prospects of in vitro regeneration and genetic transformation expression and stability of transgenes modification of traits in almost all the important legumes, for example: soybean; peanut; pea; french bean; chick pea; pigeon pea; cowpea; mung bean; black gram; azuki bean; lentil; Lathyrus; lupinus; Lotus spp; Medicago spp; Trifolium spp; Winged bean; Guar; and tree legumes for their improvement. Written by international experts, these volumes will be of great value to researchers, as well as graduate students and all those requiring an advanced level overview of the subject area.

* Provides new insights into materials science
* Indicates the value of biology in materials science
* Demonstrates how new interdisciplinary studies are influencing the fields of materials science and chemistry
* Surveys this new field and shows what progress has been made as well as indicating the potential of these applications
* Leading scientists review biomimetic approaches to the synthesis and processing of nanoparticles, thin patterned films, ceramics, and organic-inorganic composites
* Focuses on molecule synthesis, templating, organized construction and microstructural processing of biomimetic materials
related titles are:
- Meyers: Molecular Biology and Biotechnology
- Silver: Biocompatibility Vol.1: Polymers

Bionanotechnology towards Green Energy explains the role of bionanotechnology in the next generation technologies of green energy from an interdisciplinary and sustainability perspective. Chapters cover different roles of bionanotechnology such as applications of bio-nano enabled materials/coatings, scaling-up of green energy production, design and synthesis of bio-inspired nanomaterials and their applications, Bio-nanofluids based photovoltaic thermal system, the use of bio-templated and biomimetic materials, and so forth. It focuses on waste-to-energy conversion and fixing intricate environmental issues. Key features: Provides detailed coverage of green energy production through bionanotechnological intervention Reviews future research needs on bionanotechnology in the green energy sector and scientific challenges in the mitigation of energy crisis Deals with cutting-edge research on microbial synergism in biohydrogen production and storage Discusses the fabrication of bio-nano/ hybrid electrode materials for supercapacitors and energy storage devices Includes extensive illustrations, case studies, summary tables, and up-to-date references This book is aimed at researchers and professionals in bionanotechnology, energy sciences, and environmental engineering.

Offering a comprehensive overview of biofuels and bioenergy systems, Biofuels: Technologies, Policies, and Opportunities describes advances in technologies and global policies around biofuels as a renewable energy source. It discusses the basics of biofuel and bioenergy systems and current status and potential challenges in developed and developing countries. The book also highlights the questions that should be asked, available options, and processes (conventional and advanced) to enhance biofuel production. Details how technological interventions can influence the operation of an effective bioenergy system. Presents information regarding Renewable Energy Directives and global policies related to energy chains, energy models, market status, and appropriateness of technology selection for different generations of biofuel generation. Covers socio-economic aspects and techno-economic feasibility as well as a detailed Life cycle simulations (LCS)approach, revealing the real constraints being faced in the biofuels sector. Helps bioenergy professionals to prepare a roadmap for day-to-day operations. Describes recent advances such as biohythane, advanced oxidation process, and nanocatalyzed pretreatment for biofuel generation from wastewater. Addresses the most commonly discussed issues in the biofuel sector and the rationales underpinning them. Written for professionals, academic researchers, decision makers, and policymakers in the biofuel sector, this book provides readers with a wide-ranging review of current research and developments in the respective field.

This book puts together all aspects of valorization of vegetable and fruit wastes (VFWs) into different biocommodities and platform chemicals using fermentation and non-fermentation processes. VFWs are a special group of solid waste (biomass) that needs to be characterized to understand the nature of applications as raw materials and to propose an appropriate methodology for bioprocessing into value-added commodities. VFWs provide favorable conditions for the growth of microorganisms, and this opens up great opportunities for their use in fermentation processes. For example, VFWs can be used as a solid support, carbon, and nutrient source in fermentation for the production of a variety of value-added biocommodities such as enzymes, single-cell proteins, bioadsorbents, phenolic bioactive compounds, aroma and flavor compounds, and platform chemicals like lactic acid, bioethanol, and biobutanol. Researchers and academics in the area of environmental science and engineering, chemical engineering, biotechnology, life science, and food science and technology, undergraduate and graduate students, industry professionals, and policymakers will find this publication useful. Bioprocessing of agro-wastes is a recent technology for developing novel bioproducts. This book will also be of interest to the general public as a reference for all those interested in waste management.

This book caters to the need of researchers working in the ever-evolving field of agricultural biotechnology. It discusses and provides in-depth information about latest advancements happening in this field. The book discusses evolution of plant tissue culture techniques, development of doubled haploids technology, role of recombinant-DNA technology in crop improvement. It also provides an insight into the global status of genetically modified crops, use of RNAi technology and mi-RNAs in plant improvement. Chapters are also dedicated for different branches of 'omics' science including genomics, bioinformatics, proteomics, metabolomics and phenomics along with the use of molecular markers in tagging and mapping of various genes/QTLs of agronomic importance. This book also covers the role of enzymes and microbes in agriculture in productivity enhancement. It is of interest to teachers, researchers of biotechnology and agriculture scientists. Also the book serves as additional reading material for undergraduate and postgraduate students of biotechnology, agriculture, horticulture, forestry, ecology, soil science, and environmental sciences. National and international biotechnologists and agricultural scientists will also find this to be a useful read.

This book presents a detailed overview and critical evaluation of recent advances and remaining challenges in improving nutritional quality and/or avoiding the accumulation of undesirable substances in plants using a variety of strategies based on modern biological tools and techniques. Each review chapter provides an authoritative and insightful account of the various aspects of nutritional enhancement of plants. In the course of the last two decades, several food crops rich in macro- and micronutrients have been developed to improve health and protect a large section of the populace in developing countries from chronic diseases. Providing extensive information on these developments, this book offers a valuable resource for all researchers, students and industrialists working in agriculture, the plant sciences, agronomy, horticulture, biotechnology, food and nutrition, and the soil and environmental sciences.

Innovation is added value to a known process. Bioprinting: Techniques and Risks for Regenerative Medicine aims to stimulate a scientifically grounded, interdisciplinary, multiscale debate and exchange of ideas using the techniques described in the book. 3D printing and additive manufacturing evolved from within the field of Cell Biology will have the ability to recreate cells queried from large amounts of phenotypic and molecular data. Stem Cell biologists, biotechnologists and material engineers, as well as graduate students will greatly benefit from the practical knowledge and case examples provided throughout this book.

The growing scale of plant-based chemicals for industrial use has generated considerable interest in developing methods to meet their desired production levels. Among various available strategies for their production, the development of Agrobacterium rhizogenes mediated hairy root cultures (HRCs) is generally considered the most feasible approach. Additionally, several proof-of-principle experiments have demonstrated the practical feasibility of HRCs in the plant-based remediation of environment pollutants, biotransformation of important compounds, and production of therapeutic proteins. Given that hairy root biotechnology has now been recognized as a promising and highly dynamic research area, this book offers a timely update on recent advances, and approaches hairy roots as a multifaceted biological tool for various applications. Further, it seeks to investigate the loopholes in existing methodologies, identify remaining challenges and find potential solutions by presenting well thought-out scientific discussions from various eminent research groups working on hairy root biotechnology. This book provides detailed conceptual and practical information on HRC-based research, along with relevant case studies. The content is divided into three broad sections, namely (i) Hairy Roots and Secondary Metabolism, (ii) Progressive Applications, and (iii) Novel Approaches and Future Prospects. By informing the research and teaching community about the major strides made in HRC-based interventions in plant biology and their applications, the book is sure to spark further research in this fascinating field.

This comprehensive and extensively classroom-tested biophysics textbook is a complete introduction to the physical principles underlying biological processes and their applications to the life sciences and medicine. The foundations of natural processes are placed on a firm footing before showing how their consequences can be explored in a wide range of biosystems. The goal is to develop the readers' intuition, understanding, and facility for creative analysis that are frequently required to grapple with problems involving complex living organisms. Topics cover all scales, encompassing the application of statics, fluid dynamics, acoustics, electromagnetism, light, radiation physics, thermodynamics, statistical physics, quantum biophysics, and theories of information, ordering, and evolutionary optimization to biological processes and bio-relevant technological implementations. Sound modeling principles are emphasized throughout, placing all the concepts within a rigorous framework. With numerous worked examples and exercises to test and enhance the reader's understanding, this book can be used as a textbook for physics graduate students and as a supplementary text for a range of premedical, biomedical, and biophysics courses at the undergraduate and graduate levels. It will also be a useful reference for biologists, physicists, medical researchers, and medical device engineers who want to work from first principles.

The replacement of fossil-derived compounds by bio-based fuels and chemicals is crucial for the implementation of a sustainable bioeconomy. In this context, microorganisms are key players for biofuels' production from renewable sources. Biotechnological biofuel production processes require conversion microorganisms capable of both efficiently assimilating renewable low-cost carbon sources and diverting their metabolisms towards the specific biofuel. Exploring the wide diversity of microorganisms available on Earth will surely aid to make the production of green fuels a reality. This book gives a wide overview of different microbial-based processes for green fuels production. The book also includes techno-economic analysis and highlights strategic, commercial and environmental interests in promoting green fuels. All these facts make this book very valuable not only for the scientific community but also for biofuel companies and policy makers.

General compendium of HDAC inhibitors with deep emphasis on toxicity issues of synthetic HDAC inhibitors Various groups of natural HDAC inhibitors, their representatives and premier sources Cyclic tetrapeptides of natural origin and their importance as cancer chemotherapeutic agents Hydroxamates and depsipeptides from natural sources and their promising role in cancer therapy Natural Flavonoids, their HDAC inhibitory tendency and marvellous anticancer activity Non-flavonoid natural HDAC inhibitors and their pleasing cytotoxic effects towards cancer models Combined therapy involving natural flavonoids with other anticancer molecules for synergistic and additive benefits against cancer models Non-flavonoid HDAC inhibitors and conventional drugs in collaborative mode against aggressive malignancies Nanotechnology based delivery of natural HDAC inhibitors for greater therapeutic efficacy over traditional combinatorial therapy

Modeling of Microscale Transport in Biological Processes provides a compendium of recent advances in theoretical and computational modeling of biotransport phenomena at the microscale. The simulation strategies presented range from molecular to continuum models and consider both numerical and exact solution method approaches to coupled systems of equations. The biological processes covered in this book include digestion, molecular transport, microbial swimming, cilia mediated flow, microscale heat transfer, micro-vascular flow, vesicle dynamics, transport through bio-films and bio-membranes, and microscale growth dynamics. The book is written for an advanced academic research audience in the fields of engineering (encompassing biomedical, chemical, biological, mechanical, and electrical), biology and mathematics. Although written for, and by, expert researchers, each chapter provides a strong introductory section to ensure accessibility to readers at all levels.

Micropropagation of plants is a multi billion dollar industry being practiced in hundreds of sm all and large nurseries and commerciallabo- ratories throughout the world. At present, it is the only component of plant biotechnology which has been commercially exploited on such a large scale, especially for the production of ornamentals. Now micropropagation of trees and medicinal plants has also assumed great importance. With recent progress made in the propagation of fruit and forest trees, and the immediate need for afforestation and planting of orchards, propagules and plantlets are required quickly and in large numbers. Taking these points into consideration High-Tech and Micropropagation I, II, III, and IV were published in 1991 and 1992. The present two volumes, High-Tech and Micropropagation V and VI, comprise 51 chapters contributed by international experts from 24 countries. High-Tech and Micropropagation V comprises 24 chapters arranged into the following three seetions: 1. Vegetables and fruits (garlic, Amaranthus, Brassica oleracea, pep- per, watermelon, cassava, banana, Myrtus communis, passionfruit, Polymnia sonchifolia, pepino, and spinaeh) H. Grasses (bamboos, Caustis dioica, Dendrocalamus, Miscanthus x giganteus, sugarcane) In. Trees (Aegle marmelos, Eucalyptus, Fraxinus excelsior, luglans cinerea, Pinus virginiana, Prosopis, and Vlmus species) High-Tech and Micropropagation VI comprises 27 chapters arranged in two sections: 1. Ornamental and aromatic plants (Amaryllis, Anthurium, Blandfordia, bromeliads, Campanula, Coleus, Ctenanthe, Cyclamen, Daphne, Dracaena, Gerbera, Helianthemum, Hippeastrum, Leucojum, Mammillaria, Maranta, Mediocactus, Mussaenda, Narcissus, Otacanthus, ponytail palm, Prunus tenella, Spiranthes, and Zinnia) II.

This volume focuses on how waste biomass can be transformed into useful biomaterials, food and feed, fuel, and chemicals by using various processes such as chemical, physical, thermal, biological, and biotechnological procedures. Biomass from biowastes, such as agriculture crop residues, wood processing residues, forest residues, food waste, industrial waste, and municipal solid waste, have emerged as potential substrates for bioenergy production. This volume explores the key features of biotechnology for waste biomass utilization, presenting scientific and technical literature on sustainable waste biomass management as well as for biomass conversion for biofuels, chemicals, and other new commercial products. It discusses a variety of novel biotechnical applications and interventions, including microbial fermentation and anaerobic digestion, biotechnological modes of xylooligosaccharides production, multifaceted utilization of microalgal biomass, vermiculture and vermicomposting, and more. Key features: Provides the most recent information about waste biomass utilization for the production of biofuels and biochemicals Shows a wide range of novel technologies in the field of biotechnology towards waste biomass utilization Focuses on the utilization of microbial resources for waste biomass conversion into value-added products Explores methods for food wastes and crop wastes conversion into biofuels and biochemicals Provides the scientific information describing various examples and case studies which aid gaining knowledge to researchers and academicians With chapters from eminent researchers who have significant global experience in the field of waste biomass management, this volume delivers a wealth of valuable information for researchers involved in bioenergy utilization. It will also be an essential source for academicians, researchers, economists, policymakers, and policy analysts.

Provides an overview of the biowaste as a sustainable source in the field of biofuel production Includes effective conversion parameters of the biowaste feedstocks and their classification Summarizes current research into the development and exploitation of new biofuel sources Discusses improvement of pilot scale scalability, and chemical processing and design flow Presents relevant and realistic global explanations on biowaste management techniques for biofuels

Unique selling point: Advanced AI solutions for problems in genetics, virology, and related areas of life science Core audience: Researchers in bioinformatics Place in the market: High-level reference book on advanced applied technology

Herbal drugs play a pivotal role in modern medicine and pharmaceutical care however only limited biotechnology application has been seen in medicinal plants. Revolutions in high-throughput approaches emphasize omics approaches, such as genomics, transcriptomics, proteomics, and metabolomics. A volume in the Exploring Medicinal Plants series, this book provides a comprehensive and in-depth analysis of breakthroughs in high-throughput approaches for the research of medicinal plants. Exploring the principles and applications of omics technologies, this book is essential for those working on or are involved in the modern research of medicinal and aromatic plants. There is also a strong focus on practical implications of these technologies through exploring the safety aspects and conservation strategies of various plants. From informative discussions on the latest research to a holistic evaluation of their potential applications, this book appeals to students, researchers and professionals working with medicinal and aromatic plants, as well as healthcare professionals interested in the area.