A Fractal Analysis of Chemical Kinetics with Applications to Biological and Biosensor Interfaces analyzes the kinetics of binding and dissociation of different analytes by different biosensor techniques, demonstrating, and then comparing each other. Emphasis is on newer instrumentation techniques, such as surface plasmon resonance imaging (SPRi), and classical techniques, such as surface plasmon resonance (SPR), and finally, DNA biosensors and nanobiosensors. In addition, the closing chapter includes discussion of biosensor economics.

This edited book deals with latest comprehensive information on conventional and high throughput techniques and technologies that are recently used to study plant microbial interface for agricultural research and enhancing plant productivity. Plant microbiota are important for many plant growth promotion activity and agricultural productivity and are sustainable green technology for enhancing agricultural productivity under changing environment. The book covers recent information about the plant associated microbiota and their ecology. It discusses technologies to isolate and test microbiota inhabiting in different portion of plants. The book explores the conventional methods as well as the most recently recognized high throughput technologies which are important for productive agroecosystems to feed the growing global population. This book is of interest to teachers, researchers, microbiologist, plant and environmental scientist and those interested in environment stewardship around the world. Also the book serves as additional reading material for undergraduate and graduate students of agriculture, forestry, ecology, soil science, and environmental sciences and policy makers to be a useful to read.

This book presents deliberations on molecular and genomic mechanisms underlying the interactions of crop plants to the abiotic stresses caused by heat, cold, drought, flooding, submergence, salinity, acidity, etc., important to develop resistant crop varieties. Knowledge on the advanced genetic and genomic crop improvement strategies including molecular breeding, transgenics, genomic-assisted breeding, and the recently emerging genome editing for developing resistant varieties in pulse crops is imperative for addressing FHNEE (food, health, nutrition, energy, and environment) security. Whole genome sequencing of these crops followed by genotyping-by-sequencing has provided precise information regarding the genes conferring resistance useful for gene discovery, allele mining, and shuttle breeding which in turn opened up the scope for 'designing' crop genomes with resistance to abiotic stresses. The nine chapters each dedicated to a pulse crop in this volume elucidate on different types of abiotic stresses and their effects on and interaction with the crop; enumerate on the available genetic diversity with regard to abiotic stress resistance among available cultivars; illuminate on the potential gene pools for utilization in interspecific gene transfer; present brief on classical genetics of stress resistance and traditional breeding for transferring them to their cultivated counterparts; depict the success stories of genetic engineering for developing abiotic stress-resistant crop varieties; discuss on molecular mapping of genes and QTLs underlying stress resistance and their marker-assisted introgression into elite varieties; enunciate on different genomics-aided techniques including genomic selection, allele mining, gene discovery, and gene pyramiding for developing adaptive crop varieties with higher quantity and quality of yields, and also elaborate some case studies on genome editing focusing on specific genes for generating abiotic stress-resistant crops.

This book focuses on signaling molecules in plant defense, outlining some of the most important cellular and chemical plant defense strategies during periods of stress and growth. Written by leading experts, it covers topics such as the diversity of plant-growth-promoting fungi, the gene-to-metabolite network of plant-microbe interactions, modulation of plant cellular responses to stress, and how plant nutritional deficiency affects crop production. Together with the companion volume Bioactive Molecules in Plant Defense: Saponins, this book offers an essential source of information for postgraduate students and researchers interested in plant pathology, mycology and sustainable agriculture.

Today's challenge, especially for many newcomers to the regulated industry, is not necessarily to gather regulatory information, but to know how to interpret and apply it. The ability to discern what is important from what is not, and to interpret regulatory documents correctly, provides a valuable competitive advantage to any newcomer or established professional in this field. An Overview of FDA Regulated Products: From Drugs and Medical Devices to Food and Tobacco provides a valuable summary of the key information to unveil the meaning of critical, and often complex, regulatory concepts. Concise and easy to read with practical explanations, key points, summaries and case studies, this book highlights the regulatory processes involved in bringing an FDA regulated product from research and development to approval and market. Although the primary focus will be on the US system, this book also features global perspectives where appropriate. A valuable resource for students, professors and professionals, An Overview of FDA Regulated Products illustrates the most important elements and concepts so that the reader can focus on the critical issues and make the necessary connections to be successful.

Advances in Applied Microbiology, Volume 107, continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas, with this updated volume including chapters covering the roles and applications of siderophores, biological oxidation of iron sulphides, production of biomass and biofuel feedstocks from microalgae, advances in the microbial ecology of biohydrometallurgy, bacterial synthesis of Se nanoparticles, and siderophores in environmental research, amongst other discussions.

This book comprises a collection of chapters on advances in green nanomaterials. The book looks at ways to establish long-term safe and sustainable forms of nanotechnology through implementation of nanoparticle biosynthesis with minimum impact on the ecosystem. The book looks at synthesis, processing, and applications of metal and metal oxide nanomaterials and also at bio-nanomaterials. The contents of this book will prove useful for researchers and professionals working in the field of nanomaterials and green technology.

Modern Vibrational Spectroscopy and Micro-Spectroscopy: Theory, Instrumentation and Biomedical Applications unites the theory and background of conventional vibrational spectroscopy with the principles of microspectroscopy. It starts with basic theory as it applies to small molecules and then expands it to include the large biomolecules which are the main topic of the book with an emphasis on practical experiments, results analysis and medical and diagnostic applications. This book is unique in that it addresses both the parent spectroscopy and the microspectroscopic aspects in one volume. Part I covers the basic theory, principles and instrumentation of classical vibrational, infrared and Raman spectroscopy. It is aimed at researchers with a background in chemistry and physics, and is presented at the level suitable for first year graduate students. The latter half of Part I is devoted to more novel subjects in vibrational spectroscopy, such as resonance and non-linear Raman effects, vibrational optical activity, time resolved spectroscopy and computational methods. Thus, Part 1 represents a short course into modern vibrational spectroscopy. Part II is devoted in its entirety to applications of vibrational spectroscopic techniques to biophysical and bio-structural research, and the more recent extension of vibrational spectroscopy to microscopic data acquisition. Vibrational microscopy (or microspectroscopy) has opened entirely new avenues toward applications in the biomedical sciences, and has created new research fields collectively referred to as Spectral Cytopathology (SCP) and Spectral Histopathology (SHP). In order to fully exploit the information contained in the micro-spectral datasets, methods of multivariate analysis need to be employed. These methods, along with representative results of both SCP and SHP are presented and discussed in detail in Part II.

Soybean (Glycine max L. (Merr)) is one of the most important crops worldwide. Soybean seeds are vital for both protein meal and vegetable oil. Soybean was domesticated in China, and since last 4-5 decades it has become one of the most widely grown crops around the globe. The crop is grown on an anticipated 6% of the world's arable land, and since the 1970s, the area in soybean production has the highest percentage increase compared to any other major crop. It is a major crop in the United States, Brazil, China and Argentina and important in many other countries. The cultivated soybean has one wild annual relative, G. soja, and 23 wild perennial relatives. Soybean has spread to many Asian countries two to three thousand years ago, but was not known in the West until the 18th century. Among the various constraints responsible for decrease in soybean yields are the biotic and abiotic stresses which have recently increased as a result of changing climatic scenarios at global level. A lot of work has been done for cultivar development and germplasm enhancement through conventional plant breeding. This has resulted in development of numerous high yielding and climate resilient soybean varieties. Despite of this development, plant breeding is long-term by nature, resource dependent and climate dependent. Due to the advancement in genomics and phenomics, significant insights have been gained in the identification of genes for yield improvement, tolerance to biotic and abiotic stress and increased quality parameters in soybean. Molecular breeding has become routine and with the advent of next generation sequencing technologies resulting in SNP based molecular markers, soybean improvement has taken a new dimension and resulted in mapping of genes for various traits that include disease resistance, insect resistance, high oil content and improved yield. This book includes chapters from renowned potential soybean scientists to discuss the latest updates on soybean molecular and genetic perspectives to elucidate the complex mechanisms to develop biotic and abiotic stress resilience in soybean. Recent studies on the improvement of oil quality and yield in soybean have also been incorporated.

New and Future Developments in Microbial Biotechnology and Bioengineering: Microbial Biotechnology in Agro-environmental Sustainability describes, in detail, the various roles of microbial resources in the management of crop diseases and how microbes can be used as a source of income for biomass and bioenergy production. In addition, the book covers microbial inoculants as bio-fertilizers to enhance crop productivity, along with degraded land restoration. Users will find the latest information in the field of microbial biotechnology and its further applications in bio-fertilizers, bio-pesticides, its generation as an alternative source of energy, restoration degraded and marginal lands, the mitigation of global warming gases, and more.

This volume contains selects papers presented during the 2nd International Conference on Environmental Geotechnology, Recycled Waste Materials and Sustainable Engineering, held in the University of Illinois at Chicago. It covers the recent innovations, trends, and concerns, practical challenges encountered, and the solutions adopted in waste management and engineering, geotechnical and geoenvironmental engineering, infrastructure engineering, and sustainable engineering. This book will be useful for academics, educators, policy makers and professionals working in the field of civil engineering, chemical engineering, environmental sciences and public policy.

This fascinating study describes efforts to define and protect traditional knowledge and the associated issues of access to genetic resources, from the negotiation of the Convention on Biological Diversity to The Declaration on the Rights of Indigenous Peoples and the Nagoya Protocol. Drawing on the expertise of local specialists from around the globe, the chapters judiciously mix theory and empirical evidence to provide a deep and convincing understanding of traditional knowledge, innovation, access to genetic resources, and benefit sharing. Because traditional knowledge was understood in early negotiations to be subject to a property rights framework, these often became bogged down due to differing views on the rights involved. New models, developed around the notion of distributive justice and self-determination, are now gaining favor. This book suggests - through a discussion of theory and contemporary case studies from Brazil, India, Kenya and Canada - that a focus on distributive justice best advances the interests of indigenous peoples while also fostering scientific innovation in both developed and developing countries. Comprehensive as well as nuanced, Genetic Resources and Traditional Knowledge will be of great interest to scholars and students of law, political science, anthropology and geography. National and international policy makers and those interested in the environment, indigenous peoples' rights and innovation will find the book an enlightening resource. Contributors: T. Bubela, J. Carbone, R. Crookshanks, L. DeBusschere, G. Dutfield, E.R. Gold, D.S. Hik, A. Kumbamu, C. Lawson, C. Metcalf, S. Nickels, K. Nnadozie, P.W.B. Phillips, E.B. Rodrigues Jr, T. Williams, S. Zhang

This book reviews the potential of next-generation point-of-care diagnosis in healthcare. It also discusses the printed chip-based assay (Lab-on-a-Chip, Lab-on-a-PCB) for rapid, inexpensive biomarkers detection. The book presents the development of sensory systems based on the use of nanomaterials. It examines different biosensors for medical diagnosis using surface modification strategies of transducers. It presents electrochemical concepts based on different nanobiomaterials and nanocomposites for cancer theranostics. Notably, the book examines the recent advances in wearable, cost-effective hemodynamic sensors to detect diseases at an early stage. It further explores the combination of redox cycling and electrochemical detection to develop ultrasensitive and reproducible biosensors for point-of-care testing. Finally, the book summarizes the significant challenges in the point of care diagnostics and its future opportunities in healthcare.

Biomass, Biofuels and Biochemical: Biohydrogen, Second Edition, provides general information, basic data and knowledge on one of the most promising renewable energy sources, including its production and applications. The book describes a green technology for abating environmental crisis and enabling the transformation into a sustainable future. Researchers, students and science enthusiasts alike will appreciate this holistic view of biohydrogen production, which details the functional mechanisms employed, operational configurations, influencing factors and integration strategies. With 50% more content, this new edition outlines the scaling of processes and features material from experienced international researchers working at the interface of biotechnology and engineering. Hydrogen is an energy carrier and is available in chemically combined forms in water, fossil fuels and biomass. About 95 % of current hydrogen requirements are produced through fossil fuel sources. Being a clean energy source, its future widespread use as a fuel is likely to be in the transportation and distributed power generation sectors.

This volume describes the identification of emerging organic pollutants, mainly from industrial sources, their associated toxicological threats, and the latest green methods and biotechnological solutions to abate harmful impacts on people and the environment. The chapters present reviews on current applied toxicology research, occupational health hazards and green remedial solutions for pollution control in terrestrial and aquatic environments, with the aim of raising public awareness of these issues and providing chemists, toxicologists and environmental scientists with the knowledge to combat organic pollutants through sustainable means. Readers will learn about the multi-dimensional applications of materials and processes which harvest energy out of environmental remediation technologies, as well as the roles of biotechnology and nanotechnology in addressing high pollutant load. Specific attention is paid to technologies that draw energy through wastewater remediation, as this covers the primary means by which organic pollutants are introduced into the environment from industry and other sources. The book will be of use to pollution control boards, industry regulators, and students and researchers in the fields of biotechnology, biomedical science, hydrology and water chemistry.

This volume details techniques involved to study aquatic pathogens that cause infections, especially in fish. Chapters guide readers through a wide range of basic and advanced methods, viral and fungal pathogens, probiotic bacteria, treatment of pathogens using seaweed extract, medicinal plant extracts, and actinomycetes. Authoritative and cutting-edge, Aquaculture Microbiology aims to be a useful practical guide to researches to help further their study in this field. 

This unique book covers the molecular aspects of plant stress and the various industrial applications. Chapters cover many important topics in the biology of plant stress, including morphological and physiological changes of plants due to accumulation of pollutants; the types of stress for enhanced biofuel production from plant biomass; plant adaptation due to different types of environmental stresses; potential applications of microRNAs to improve abiotic stress tolerance in plants; plant resistance to viruses and the molecular aspects; photosynthesis under stress conditions; plant responses to weeds, pests, pathogens, and agrichemical stress conditions; and plant responses under the stress of drought. Key features: * Describes the different types of plant stress * Details the current and possible applications of plant stress biology * Presents several case studies that include applications of plant stress * Explores plant stress biology for applications in biofuel science Plant Stress Biology: Progress and Prospects of Genetic Engineering will be useful for researchers in diverse fields as well as for plant biologists, environmental biologists, faculty, and students. The book will also be helpful for further advancement of research in the area of plant stress biology.

Describes technological advancements for bioethanol production from lignocellulosic waste Provides a roadmap for the production and utilization of 2G biofuels Introduces the strategic role of metabolic engineering in the development of 2G biofuels Discusses technological advancements, life cycle assessment and prospects Explores novel potential lignocellulosic biomass for 2G biofuels

A compilation of up to date reviews of topics in biotechnology and medical field.

Applications of Nanocomposite Materials in Orthopedics provides a solid understanding of recent developments in the field of nano-composites used in orthopedics. The book covers joint replacement, the load bearing capability of fractured bones, bone soft tissue regeneration, hard tissue replacement, artificial bone grafting, bone repair, bone tissue transplantations, and related topics, thus helping readers understand how to resolve problems associated with bone fracture and orthopedic surgery. A variety of nanocomposite materials are discussed, with their properties and preparation methods given.

This book describes the discovery of molecules from unexploited extreme marine environments, and presents new approaches in marine genomics. It combines the current state of knowledge in marine genomics and advanced natural products' chemistry to pursue the sustainable production of novel secondary metabolites (lead compounds), as well as pharmacologically active peptides/proteins, with antimicrobial, neuroprotective, anti-osteoporotic, anti-protozoan/anti-plasmodial, anti-ageing and immune-modulating effects. Further, it employs molecular-biology-based approaches and advanced chemical techniques to obtain and to select candidate compounds for pre-clinical and clinical studies.

This book presents a broad perspective on saponins as important natural products with a key role in plant defense. The presence of saponins has been reported in several plant species, and many types of saponins have been found to exhibit significant antifungal activities. In addition to their role in plant defense, saponins are of increasing interest for drug research, as they are active ingredients in several traditional medicines and hold potentially valuable pharmacological properties. In this book, the authors briefly introduce readers to saponin accumulation in various plant organs, with a specific focus on their structure classification and diversity. Readers will find detailed information on the saponin structure-activity relationship and saponins' vital role in sustainable agriculture as a chemical barrier to pathogen attack. The latest techniques for isolating, identifying, and quantifying saponins are also discussed. In the closing chapter, the authors outline the recent metabolic engineering strategies applied to improve saponin glycosides production and their potential applications in plant disease resistance. This book and the companion volume Bioactive Molecules in Plant Defense: Signaling in Growth and Stress offer vital resources for all researchers and students interested in plant pathology, mycology and sustainable agriculture.