This is the fourth in a series of five letter reports that provide an independent review of the more than 30 evidence reports that NASA has compiled on human health risks for long-duration and exploration spaceflights.This letter report reviews eight evidence reports and examines the quality of the evidence, analysis, and overall construction of each report; identifies existing gaps in report content; and provides suggestions for additional sources of expert input. Table of Contents Front Matter 2016 Letter Report Appendix A: Meeting Agendas Appendix B: Committee Biographical Sketches

The paradox of global universe rotation, as it seems, is today one of its greatest mysteries of nature. The idea originated less than a hundred years, and getting the most correct answer was possible only after the creation of modern cosmology. In this book, the authors forward their visions on the universal rotation problem. At the same time, the arguments in favor of its global rotation absence are presented as well. In fact, different theoretical and observational aspects of evidence that supports the possible rotation of the universe on different cosmological scales were investigated. It was shown that there are correlations between angular momentum and size of the structures. The presented observational picture is that the galaxies, their pairs and compact groups have a non vanishing angular momentum. Moreover, these momenta have the definite tendency to their alignment. An analysis of the distribution of position angles of more than ten thousand extended radio sources shows that the spatial orientation of axes of these objects is anisotropic: they are mostly oriented not in the direction of the celestial pole, but rather in the equatorial direction. The probability that the sky distribution of axes is isotropic is less than 0.00004. It was argued that our universe rotates differentially. Based on the spinning part of Papapetrous equations, it was shown that the rotation radically depends on the properties of the epoch of universal growth. The universes angular velocities have been calculated for three main cosmological epochs: the matter dominated epoch, the transient from matter to vacuum dominated epoch, and the vacuum dominated epoch. In the framework of general relativity, the nonstationary Bianchi type VIII cosmological models with rotation were proposed. As the sources of gravity have been chosen, they are known as comoving perfect fluid with non-comoving dust, comoving perfect fluid with pure radiation, and comoving anisotropic fluid. All of the models contain a rotating dark energy. Recent observations, such as the anomalies in the temperature angular distribution of the cosmic microwave background (CMB), indicate a preferred direction in the universe. The foundation of modern cosmology, however, relies on a homogeneous and isotropic distribution of matter on large scales. Here, the authors consider the preferred axis in the CMB parity violation. The authors also found that this axis coincides with the preferred axes of the CMB quadrupole and octopole, and they all align with the direction of the CMB kinematic dipole, which does not have a cosmological origin. The several exact non-stationary Goedel-type solutions that belong to a large class of shear-free spatially homogeneous spacetimes were presented. The observational effects of the universal rotation in cosmology are analyzed. It was shown that the pure cosmic rotation does not produce either causality violations, parallax effects, or anisotropy of the microwave background radiation. A possible way to detect the cosmic rotation is to search for the angular dependencies of the standard cosmological tests, and a number of new observations can be proposed.

NASA operates a large number of space science missions, approximately three-quarters of which are currently in their extended operations phase. They represent not only a majority of operational space science missions, but a substantial national investment and vital national assets. They are tremendously scientifically productive, making many of the major discoveries that are reported in the media and that rewrite textbooks. Extending Science ? NASA's Space Science Mission Extensions and the Senior Review Process evaluates the scientific benefits of missions extensions, the current process for extending missions, the current biennial requirement for senior reviews of mission extensions, the balance between starting new missions and extending operating missions, and potential innovative cost-reduction proposals for extended missions, and makes recommendations based on this review. Table of Contents Front Matter Summary 1 Introduction 2 The Scientific Benefits of Mission Extensions 3 Review of Extended Missions by NASA 4 The Balance of New Missions Versus Extended Missions 5 Innovative Cost Reductions for Extended Missions Appendixes Appendix A: Statement of Task Appendix B: Scientific Discoveries of the Lunar Reconnaissance Orbiter and Opportunity Rover During Extended Phase Appendix C: NASA Science Mission Directorate Budgets by Division for Fiscal Year 2016 Appendix D: Extended Mission and Senior Review References in Decadal Surveys Appendix E: Biographies of Committee Members and Staff Appendix F: Acronyms