Lippincott (R) Connect Featured Title Purchase of the new print edition of this Lippincott (R) Connect title includes access to the digital version of the book, plus related materials such as videos and multiple-choice Q&A and self-assessments. Lippincott (R) Illustrated Reviews: Immunology, 3rd Edition, offers an engaging, vividly illustrated presentation and all of the popular learning features of the Lippincott (R) Illustrated Review series to reinforce essential immunology concepts and connect basic science to real-life clinical situations. Like other titles in this series, this dynamic resource follows an intuitive outline organization and boasts a wealth of vibrant illustrations and study aids that clarify complex information and ensure retention. Whether used as a review text for a short immunology course or paired with Lippincott (R) Illustrated Reviews: Microbiology for a combined microbiology/immunology course, this revised and updated edition familiarizes readers with the latest practices in immunology and emphasizes clinical application to deliver unparalleled preparation for exams and clinical practice. Revised and expanded content equips you with the most current perspectives and practices in clinical immunology. More than 300 full-color, annotated illustrations clarify complex immunology concepts in vivid detail. Clinical Application boxes demonstrate the practical application of immunology concepts in clinical scenarios. Chapter Study Questions and Answers test your retention and comprehension. NEW! Cross-references to other Lippincott (R) Illustrated Reviews titles help you grasp how immunological concepts relate to other basic sciences. Chapter summaries and chapter overviews highlight the most important concepts and takeaways in each chapter. Updated end-of-text review questions boost your test-taking confidence. Lippincott (R) Connect features: Full access to the digital version of the book with the ability to highlight and take notes on key passages for a more personal, efficient study experience. Carefully curated resources, such as interactive diagrams, audio and video tutorials, and self-assessment, all designed to facilitate further comprehension. Lippincott (R) Connect also allows users to create Study Collections to further personalize the study experience. With Study Collections you can: Pool content from books across your entire library into self-created Study Collections based on discipline, procedure, organ, concept or other topics. Display related text passages, video clips and self-assessment questions from each book (if available) for efficient absorption of material. Annotate and highlight key content for easy access later. Navigate seamlessly between book chapters, sections, self-assessments, notes and highlights in a single view/page.

With globalisation taking centre stage in the business world and multiculturalism affecting markets and societies, there is a need to understand the ways that customers respond to the changing marketplace from international and multicultural perspectives. This book is timely in addressing important themes raised in the most recent marketing literature, such as: global consumer culture, and the impact of Western culture on consumer behaviour in other countries; consumer acculturation processes, and the impact on identity conflicts and the strategies people use to manage them; globalisation vs. localised strategies, and the interaction of local and global influences on customer behaviour; climate change and global warming, the impact on consumer behaviour, and the implications for social responsibility; and cross-cultural customer research, including important methodological questions around the application of sociological, group-level measures to psychological, individual-level phenomenon in marketing contexts. The papers in this edition address those themes, reporting on studies from a range of countries, including Germany, Greece, China, and Austria, and a number of cultural groups in the UK. These papers draw on quantitative and qualitative methodologies, reflecting the full range of methods employed in contemporary consumer research. This book was originally published as a special issue of the Journal of Marketing Management.

Perfect for clinicians in both primary and secondary care settings, Allergy Essentials, 2nd Edition, covers the information you need most in your daily practice, with a strong emphasis on disease diagnosis and management. In one concise, convenient volume, it covers all common allergies in children and adults, offering authoritative content from the world's leading allergy experts in conjunction with primary care/family practitioners for a practical, balanced approach. You'll find up-to-date information on everything from basic immunology and physiology to new medications, new therapies, and individualized treatment options, allowing you to confidently integrate these changes into your practice. Offers a practical approach to evaluation, differential diagnosis, and treatment of allergic disorders, focused specifically on what the non-specialist needs to know for everyday practice. Includes new content on allergen-specific immunotherapy as well as a new chapter on precision medicine. Covers the most recent allergy tests, including blood tests, and includes current discussions of biologicals as therapeutics. Provides focused, relevant information on basic immunology and physiology, epidemiology, and allergens. Begins each chapter with a handy summary of key concepts to help you quickly identify important information. Authored by the same internationally recognized experts that produce Middleton's Allergy, the definitive text in the field. An ideal resource for primary care providers who are increasingly seeing and treating patients with allergic conditions as well as allergists who need a concise and current practice reference. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Immunology: An Illustrated Outline is both a guide to the essential principles of immunology and a concise dictionary of immunological terms. The book can be used to consolidate understanding in preparation for course exams and medical licensing exams, or as a refresher when immunology is encountered in related life sciences, such as microbiology, virology, and zoology. The book is organized into five sections that represent the major topics in basic and clinical immunology. The Sixth Edition has been comprehensively revised to highlight the latest understanding of the field, particularly in the areas of innate immune defenses and antibody-based therapeutics. Concise explanations of immunological terms Full-color illustrations and micrographs to reinforce the text Each topic is set out in single- or double-page spreads Tables collate and summarize detailed information

How early studies of inflammation led to our current views on the roles of vascular adhesion molecules.- Adhesion of leukocytes from flow: The selectins and their ligands.- Co-operative signaling between leukocytes and endothelium mediating firm attachment.- Production and presentation of chemokines by endothelial cells.- Platelet-activating factor: A signaling molecule for leukocyte adhesion.- Tight junctions and adherens junctions in endothelial cells: Structure and regulation.- The role of PECAM in leukocyte emigration.- Selective lymphocyte migration into secondary lymphoid rrgans and inflamed tissues.- Oxidation-reduction sensitive regulation of vascular inflammatory gene expression.- Quantification and imaging of vascular adhesion molecule expression in inflammatory diseases in vivo.- Leukocyte adhesion and activation in xenografts.- Control of leukocyte adhesion and activation in ischemia-reperfusion injury.- Control of leukocyte adhesion and activation in atherogenesis.

This volume provides a comprehensive and multidisciplinary overview of fibrocytes, written by the main researchers in the field. It is aimed at a broad audience of scientists and clinicians with an interest in the role of circulating fibrocytes in the etiopathogenesis of different fibrosing disorders, atherosclerosis, autoimmunity, and cancer.

This new edition explores lab protocols describing new techniques to study cytotoxic T-cells (CTLs), as well as chapters of a more general discursive nature, all with an emphasis on the use of systems biology in immunology. Beginning with phenotypical characterization of CTL populations, the volume continues with in vitro and in vivo cytotoxicity assays, methods to detect senescent T cells, in vivo and in vitro models to understand immune and bone cells cross-talk, microscopy and in vivo imaging, as well as "Omics" approaches and molecular methods, concluding with chapters on CTL involvement in transplantation and link microbiota-immunity. Written for the highly successful Methods in Molecular Biology series, chapters feature the kind of detail and key implementation advice for best results in the lab. Authoritative and up-to-date, Cytotoxic T-Cells: Methods and Protocols, Second Edition serves as an ideal guide for researchers working with these vital cells.

Immune responses at mucosal surfaces play a major role in host mucosal defense against microbial pathogens and in the pathogenesis of acute and chronic mucosal inflammatory diseases. immunogenetic approaches in combination with human and murine in vitro cell culture and in vivo model systems to address questions in mucosal immunity. Humans produce more immunoglobulin A (IgA) than all other antibody isotypes combined, most of which is rapidly transported into the external secretions bathing mucous membranes. It has been estimated that more than 3 grams of IgA are transported daily into mucosal secretions, carrying out a wide range of antimicrobial and anti-inflammatory functions. IgA is the second most abundant class of antibody in the bloodstream, contributing to systemic as well as secretory immunity. Recent advances in human genomics, gene regulation, structural biology, cell signaling, and immunobiology have greatly enhanced our understanding of this important class of antibody. knowledge of the biology of IgA, including structure of IgA and its interaction with Fc receptors; epithelial transport of IgA; regulation of the mucosal IgA system; biological roles of IgA, including newly discovered functions; IgA-associated diseases, and therapeutic applications for IgA. Chapters have been contributed by internationally recognized leaders in the field of IgA research, representing 8 countries on 3 continents.

Microbiota are a promising and fascinating subject in biology because they integrate the microbial communities in humans, animals, plants, and the environment. In humans, microbiota are associated with the gut, skin, and genital, oral, and respiratory organs. The plant microbial community is referred to as "holobiont," and it is influential in the maintenance and health of plants, which themselves play a role in animal health and the environment. The contents of Microbiome-Host Interactions cover all areas as well as new research trends in the fields of plant, animal, human, and environmental microbiome interactions. The book covers microbiota in polar soil environments, in health and disease, in Caenorhabditis elegans, and in agroecosystems, as well as in rice root and actinorhizal root nodules, speleothems, and marine shallow-water hydrothermal vents. Moreover, this book provides comprehensive accounts of advanced next-generation DNA sequencing, metagenomic techniques, high-throughput 16S rRNA sequencing, and understanding nucleic acid sequence data from fungal, algal, viral, bacterial, cyanobacterial, actinobacterial, and archaeal communities using QIIME software (Quantitative Insights into Microbial Ecology). FEATURES Summarizes recent insight in microbiota and host interactions in distinct habitats, including Antarctic, hydrothermal vents, speleothems, oral, skin, gut, feces, reproductive tract, soil, root, root nodules, forests, and mangroves Illustrates the high-throughput amplicon sequencing, computational techniques involved in the microbiota analysis, downstream analysis and visualization, and multivariate analysis commonly used for microbiome analysis Describes probiotics and prebiotics in the composition of the gut microbiota, skin microbiome impact in dermatologic disease prevention, and microbial communities in the reproductive tract of humans and animals Presents information in a reachable way for students, teachers, researchers, microbiologists, computational biologists, and other professionals who are interested in strengthening or enlarging their knowledge about microbiome analysis with next-generation DNA sequencing in the different branches of the sciences

This book explores the recent advances and integrations in molecular technology in food research platforms, which have revolutionized the way we discover and trace potential allergens in our food and drugs and how we utilize that for diagnosis and management. These different technologies for global allergenomic profiling in different kinds of food are discussed, including mass spectrometry, chromatography, and nuclear magnetic resonance. The book also addresses multiomics research with bioinformatics strategies in food allergy in terms of allergen characterization and quantitation, and covers applications in food allergy research from discovery to routine analysis.

Ebola: Clinical Patterns, Public Health Concerns is a concise description and discussion of the Ebola virus and disease. The intended audience is medical practitioners, including those working in endemic areas as well as health-facility planners and public health practitioners. The book fills an important gap between large texts covering not only Ebola but other hemorrhagic fever viruses and brief pamphlet-style publications on the public health aspects of the infection. In light of the recent large outbreak in West Africa, this book is a part of the developing foundation needed to deal with emerging diseases.

T cells play a vital role mediating adaptive immunity, a specific acquired resistance to an infectious agent produced by the introduction of an antigen. There are a variety of T cell types with different functions. They are called T cells, because they are derived from the thymus gland. This volume discusses how T cells are regulated through the operation of signaling mechanisms. Topics covered include positive and negative selection, early events in T cell receptor engagement, and various T cell subsets.

Allergy and Allergen Immunotherapy: New Mechanisms and Strategies is a valuable and comprehensive book that covers allergy and causative allergens and provides diagnostic and therapeutic aspects as well. With chapters from internationally recognized experts in the field, the book provides a balanced approach to enumerating pollen allergens as well as allergy diagnosis and therapeutic management and safety assessment of genetically engineered food allergens. The book features a special section on allergic diseases and allergens from tropical countries, including such countries such as India, Sri Lanka, Iran, and South Korea, giving the book a global appeal. The book is broken in the following sections: Epidemiology, Pathophysiology, and Diagnosis of Allergy Aerobiology and Allergic Diseases Pollen Allergy in the Tropics and Temperate Regions Allergy in Children Food Allergy Evaluation Allergen Immunotherapy and Anti IgE The book deals not only on basics of allergy and allergen immunotherapy but also discusses indoor environments and safety considerations of genetically modified food allergens. The first of its kind volume from the Indian subcontinent that caters to the needs of clinicians, aerobiologists, environmentalists, and regulatory agencies as well, the volume will be of immense interest for clinicians and patients of allergy as well as diagnostic and therapeutic management of allergy in tropics.

The cytokines are a group of peptides secreted by cells of the immune system such as macrophages, lymphocytes and T cells. The term cytokine is however simplistic and in fact they can be divided into functional families and have wide ranging effects from cells and molecular pathways to the whole individual. Written by distinguished scholars and experts, this book is a holistic knowledge-base to enable scientists and doctors to understand cytokines in specific or broad detail.

One hundred years have elapsed since specific allergen immunotherapy (SIT) was first employed and found to be effective in the treatment of allergic respiratory diseases. This cutting-edge issue of Immunology and Allergy Clinics offers a comprehensive review of this disease modifying treatment, exploring its history, status, and potential future. Topics covered include the mechanisms of subcutaneous allergen immunotherapy; the mechanisms of sublingual immunotherapy; optimizing efficacy of subcutaneous immunotherapy; preparation of allergen immunotherapy extraxcts; risk factors and subcutaneous immunotherapy safety; accelerated schedules and reducing risk with premedication (antihistamines, omalizumab, leucotriene antagonist); safety and efficacy of sublingual immunotherapy for allergic respiratory disease and other indications; monitoring clinical outcomes of specific immunotherapy; monitoring immunotherapy response with immunological parameters; socioeconomics and comparative effectiveness of immunotherapy; oral desensitization for food hypersensitivity; peptide and recombinant immunotherapy; intralymphatic and epicutaneous allergen-specific immunotherapy; peptide and recombinant immunotherapy; adjuvants and vector systems for allergy faccines; and future forms of immunotherapy.

This edition of Immunology and Allergy Clinics focuses on Stress and Immune-Based Diseases. Articles include: The Adverse Effects of Psychological Stress on Immunoregulatory Balance: Application to Human Inflammatory Diseases; Impact of Psychological Stress on Chronic Fatigue Syndrome Patients;Stress and Asthma;Stress and Allergic Diseases; Stress and Autoimmune Diseases;Psychosocial influences of Stress in Cancer Patients;Stress and Wound Healing and Neuroendocrine Effects of Stress on Immunity in the Elderly: mpact on Risk for Inflammatory Diseases.

This issue, Guest Edited by Drs. Shyam Mohapatra and Gary Hellermann, will include topics such as: Virus-induced airway injury and asthma inception; Pediatric infectious diseases and asthma; Rhinoviruses and inception or exacerbation of asthma; Respiratory syncytial virus infections in the adult asthmatic-role of viral subversion and host susceptibility in RSV infection; New rhinovirus clades and their significance in asthma exacerbation and airway remodeling; Metapneumovirus and asthma.

The importance of bone marrow transplantation for patients who do not have a matched sibling donor cannot be overestimated. This subject has always been in the public domain, accentuated by dramatic appeals, from time to time, to search for matched volunteer donors in the public at large. Unfortunately, the availability of such donors is limited, due to the remarkable genetic diversity of humans. Thus, although registries of such volunteers now include more than seven million individuals, we still face the problem of finding a matched donor for about 30% of patients in need. To address this burning issue, extensive clinical and basic research is performed in leading institutes around the world. This book presents updated accounts of the different aspects of this research. The scope of the book is very wide, including strategies to overcome graft vs. host (GVH) disease and graft rejection, cell therapy to prevent leukemia relapse, and a range of modalities to improve immune reconstitution after transplantation. In addition, new approaches to induce immune tolerance towards organ transplants by means of hematopoietic stem cell transplantation is extensively reviewed.

"Advances in Immunology, " a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future.
* Contributions from leading authorities and industry experts
* Informs and updates on all the latest developments in the field

This book explains how the immune system functions, namely, how individual cells of the immune system make the decision to respond or not to respond to foreign microbes and molecules, and how the critical molecules function to trigger the cellular reactions in an all-or-none (quantal) manner. To date, there has not been a complete description of the immune system and its cells and molecules, primarily because most of the information has accumulated only in the last 40 years and our understanding has been expanding rapidly only in the last 20 years. It is now clear that the cells have evolved a way to "count" the number of foreign antigenic molecular "hits," and they only react when a critical number of events have accumulated. Subsequently, control over the reaction is transferred to a systemic lymphocytotrophic hormone system that determines the tempo, magnitude and duration of the immune reaction.

This book explains in detail how the immune system, cells and molecules work for the first time. With this understanding as a basis, the pathogenesis of autoimmunity can now be understood as a mutational usurpation of the genes encoding molecules that participate in a sensitive feedback regulatory control of the immune reaction. By comparison, malignant transformation is understood as a mutational usurpation of the genes encoding the molecules that control the quantal decision to proliferate, so that normal ligand/receptor cell growth control is circumvented. This molecular understanding of the immune system is especially important for the design of successful vaccines, and also explains why vaccines fail.

Immunology of Infection, 3rd Edition, edited by two leading experts in the field, presents the most appropriate up-to-date experimental approaches in the detail required for modern microbiological research. Focusing on the methods most useful for the Microbiologist interested in analysing host-pathogen relationships, this volume will be essential reading for all researchers working in microbiology, immunology, virology, mycology and parasitology. This new edition of Immunology of Infection provides ready-to-use "recipes," and the latest emerging techniques as well as novel approaches to the tried and tested, established methods included in the successful first edition. Methods in Microbiologyis the most prestigious series devoted to techniques and methodology in the field. Established for over 30 years, Methods in Microbiology will continue to provide you with tried and tested, cutting edge protocols to directly benefit your research.

Get the most from your study time, and experience a realistic USMLE simulation with Rapid Review Microbiology and Immunology, 3rd Edition, by Drs. Ken S. Rosenthal and Michael J. Tan. This new reference in the highly rated Rapid Review Series is formatted as a bulleted outline with photographs, tables and figures that address all the microbiology and immunology information you need to know for the USMLE. And with Student Consult functionality, you can become familiar with the look and feel of the actual exam by taking a timed or a practice test online that includes 400 USMLE-style questions. Access all the information you need to know quickly and easily with a user-friendly, two-color outline format that includes High-Yield Margin Notes. Take a timed or a practice test online with more than 400 USMLE-style questions and full rationales for why every possible answer is right or wrong. Review the most current information with completely updated chapters, images, and questions, including a new chapter on Laboratory Tests for Diagnosis. Profit from the guidance of series editor, Dr. Edward Goljan, a well-known author of medical study references, who is personally involved in content review. Study and take notes more easily with the new, larger page size. Practice with a new testing platform on USMLE Consult that gives you a realistic review experience and fully prepares you for the exam. Review your understanding of how to interpret lab results in a new chapter on Laboratory Tests for Diagnosis.

This issue, Guest Edited by Dr. Mark Boguniewicz, will feature topics such as: ? Role of Fungi in Atopic Dermatitis; The Infectious Aspects of Atopic Dermatitis; Contact Allergy in Atopic Dermatitis; Role of the Nurse Educator in Atopic Dermatitis; Investigational and Unproven Therapies in Atopic Dermatitis; Addressing Psychosocial Aspects of Atopic Dermatitis; Complementary and Alternative Treatments in Atopic Dermatitis; Quality of Life in Atopic Dermatitis