Now with a new afterword covering the months-long landmark trials of Elizabeth Holmes and Sunny Balwani. ‘I couldn’t put down this thriller . . . the perfect book to read by the fire this winter.’ Bill Gates Winner of the Financial Times/McKinsey Business Book of the Year Award 2018 The riveting true story of the breathtaking rise and shocking collapse of Theranos, the multibillion-dollar biotech startup founded by Elizabeth Holmes, by the prize-winning journalist who first broke the story and pursued it to the end, despite pressure from its charismatic CEO and threats by her lawyers. In 2014, Theranos founder and CEO Elizabeth Holmes was widely seen as the female Steve Jobs: a brilliant Stanford dropout whose startup ‘unicorn’ promised to revolutionize the medical industry with a machine that would make blood testing significantly faster and easier. Backed by investors such as Larry Ellison and Tim Draper, Theranos sold shares in a fundraising round that valued the company at more than $9 billion, putting Holmes’s worth at an estimated $4.7 billion. There was just one problem: the technology didn’t work. In Bad Blood, John Carreyrou tells the riveting story of the biggest corporate fraud since Enron, a tale of ambition and hubris set amid the bold promises of Silicon Valley. ‘Chilling . . . Reads like a West Coast version of All the President’s Men.’ New York Times Book Review

This book examines patent law and policy in biotechnology across the full lifecycle of the patent, focusing on the patent bargain and the public interest. It considers the central issues of how to strike an effective balance of rights, and whether public interest is adequately safeguarded - two issues that are particularly important in areas of rapidly emerging technology. Expert contributors are brought together to explore patent eligibility in biotechnology, focusing on the fields of precision medicine, biofabrication and non-invasive prenatal testing. Chapters also explore the construction and coherence of exceptions to patentability,an examination of FRAND licensing in the context of the internet of medical things, and the possibility of using licensing to encourage or ensure the ethical use of patented technologies. With its carefully constructed analysis, this book will be an excellent resource for academic researchers, and students, in the fields of biotechnology law, pharmaceutical law and intellectual property law. It will also be useful for legal practitioners and policymakers, as well as charitable bodies and non-governmental organisations.

Biotechnology is a field that inspires complex legal and ethical debates on an international scale. Taking a fresh approach to the subject, Matthias Herdegen provides a comprehensive assessment of the regulation of biotechnology processes and products from an international and comparative perspective. Herdegen explores how regulatory approaches to controversial issues such as: stem cell research and cloning and gene therapy differ across jurisdictions due to conflicting values and risk perceptions. The book goes on to examine how international regulatory instruments aim to address these conflicting perspectives and provide judgments based on broad international consensus. Chapters explore the interaction between biotechnology and different fields of law including: human rights, intellectual property, trade law and environmental law. In doing so, a number of complex issues are raised such as the need to balance commercial interests with socio-cultural considerations and the need to ensure respect for human dignity in the pursuit of biomedical research. Providing a concise and accessible guide to a complex field of international law, this book will be of great value to those researching the law and regulation of biotechnology, biomedicine and biodiversity both within the EU and on an international scale. The book will also be a useful resource for practicing lawyers as it includes sources from a diverse range of legal systems and analyses relevant decisions by international adjudicatory bodies.

The emergence of platforms is a novel phenomenon impacting most industries, from products to services. Industry platforms such as Microsoft Windows or Google, embedded within industrial ecosystems, have redesigned our industrial landscapes, upset the balance of power between firms, fostered innovation and raised new questions on competition and innovation. Annabelle Gawer presents cutting-edge contributions from 24 top international scholars from 19 universities across Europe, the USA and Asia, from the disciplines of strategy, economics, innovation, organization studies and knowledge management. The novel insights assembled in this volume constitute a fundamental step towards an empirically based, nuanced understanding of the nature of platforms and the implications they hold for the evolution of industrial innovation. The book provides an overview of platforms and discusses governance, management, design and knowledge issues. With a multidisciplinary approach, this book will strongly appeal to academics and advanced students in management, innovation, strategy, economics and design. It will also prove an enlightening read for business managers in IT industries.

This book constitutes a fascinating and in-depth analysis of the significance of the requirement of industrial application within gene patenting and how this influences innovation in Europe and the US. The author addresses an area normally overlooked in biotechnology patenting due to the predominance of the ethical debate and, in doing so, produces a unique approach to dealing with concerns in this field. Patenting Genes: The Requirement of Industrial Application is the result of extensive research into the legal history of the industrial application requirement as well as exploration of the broad range of decisions on DNA patentability. This requirement has taken a prominent role within DNA patenting decisions in Europe since the 1998 Biotech Directive, which Dr Diaz Pozo argues has worked efficiently to control claims to human gene sequences and encouraged progress in genetic research. A broad selection of decisions on the patentability of DNA in both European Union and US courts is discussed, emphasizing the mirroring of the European approach in US cases. Academics and students of patent law and biotechnology innovation, as well as policy formulators, will find this book of great interest and value. Activists and practitioners interested in the patentability of human gene inventions in Europe and the US will also benefit from this original work.

For undergraduate and graduate courses on marketing high-tech products Provide your students with the vital information they need to successfully market high-tech products. Marketing of High-Technology Products and Innovations is the only text on the market that focuses on the unique marketing challenges that surround high-tech products and service. The third edition retains all the same concepts and materials of previous editions and includes comprehensive coverage of the latest academic research and leading-edge business practices.

The significant media coverage recently given to issues such as the international impacts of biofuel production policies, advances in synthetic biology, and the ethical implications of research involving embryonic stem cells, is indicative of the high-level of interest - among policy-makers, academics and the public - in the biotechnology revolution, its applications, impacts and control. There is also significant interest in international regulatory processes as a form of governance, and international regulation is a vital part of efforts to manage the impacts of the biotechnology revolution, since many of these are global in their nature. The book establishes the need for international regulation of biotechnology, identifying the roles it needs to play, and the issues it needs to cover. Having outlined the importance of coherence to the effective functioning of international regulatory sets, a model of coherent international regulation is established, against which the biotechnology regulations can be assessed. This book approaches the subject from an international relations perspective but also draws from, and will contribute to, literature in the fields of international law, global governance, technological governance, and science-society relations.

This book provides detailed examination of start-up companies which entered the smartphone industry following the revolution triggered by Apple with its iPhone in 2007. Analytical case studies explore the rationale behind the business models, financing cycles, and factors that helped start-ups sustain their own growth and survival. By studying these companies through the lens of entrepreneurship and competitor analysis, the author investigates not only the opportunities that can arise from technological evolution, but also the uncertainty that has developed surrounding the industry's future. Topics covered include value proposition development, evaluation of the effectiveness of business models, and market competition analysis, unveiling thought-provoking results about this rapidly changing industry. Scholars of entrepreneurship, business strategy and innovation management will find this timely book a valuable contribution to the field.

The development of biotechnological innovations is quickly becoming a globalized phenomenon as emerging nations are making major strides to compete with more developed economies. Though efforts to bridge the gap between emerging and developed nations have been successful, there are still many barriers that need to be overcome. Comparative Approaches to Biotechnology Development and Use in Developed and Emerging Nations evaluates the importance of manufacturing biotechnological products around the world. Highlighting a comparative analysis of public policies, technological policies, innovations, and marketing capabilities of developed and emerging nations, this publication is a pivotal reference source for government officers, policy makers, academics, and practitioners.

Innovation is the translation of a new method, idea, or product into reality and profit. It is a process of connected steps that accumulates into your brand or reputation. However, there can be many pitfalls and wrong turns on the road to realizing this goal. Innovation, Commercialization, and Start-Ups in Life Sciences details the methodologies necessary to create a successful life sciences start-up from initiation to exit. You will gain an appreciation for the necessary data, partnership, and skills to be acquired and the constituencies that must be satisfied along the way. The book examines how life sciences start-ups can create an exit for their investors by recognizing that a liquidity event is not consummated without due diligence. Due diligence is bigger than validating accounting transactions. It ensures the company is solving an important customer problem, demonstrating sales access, and making sure that intellectual property is impervious to competitive advancement. The due diligence process supports the telling of a compelling story to customers, investors, regulators, and acquirers. Written by an expert who has worked with more than 200 life sciences start-ups during the past decade, the book discusses specific processes and investor milestones that must be navigated to align customer, funder, and acquirer needs. It examines these processes from the perspective of marketing value through a focus on the needs of individual constituents-investors, regulators, customers, and exit candidates. The book presents data and analytical processes articulating the fundable milestones for angel and venture capital. It gives you the tools needed to create branding for public investors and more.

This work traces the history and background of the once great American consumer electronics manufacturing industry, an industry that was plagued and finally destroyed by an American-Japanese cartel subverting enforcement of our traditional trade laws. The work is not a Japan-bashing diatribe, but a call for changes in Washington, and a return to free trade in our domestic and foreign commerce.

Despite the unprecedented development and growth of knowledge during the 20th century, the evolution of a peaceful 21st century will depend on our ability to address the challenges of prosperity, sustainability, and security. From these challenges, this collection seeks to devise a research agenda to help us to understand better the knowledge-based economy.

Science and technology have acquired increasing importance in the development of contemporary societies. Governments, firms, universities, and research laboratories all take part in the process of building what has been conceptualized as national and/or regional science and technology systems. The actions of these key players and the interactions between them determine the impact of science and technology activities and, more generally, of innovation strategies on the well-being of nations. One of the most important challenges in maximizing this impact is to understand and manage the complex processes that underlie world-class science and technology research, commercialization, and management. In addition, knowledge integration in key subjects is required to enhance economic wealth, shared prosperity, and social and cultural enhancement. In this context, this volume also addresses such important topics as policy and strategies for global sustainable development.

Japanese semiconductor firms are well known for obtaining dynamics in a short period of time and achieving even global leadership. A significant portion of their success are attributable to cooperative interfirm relations and the development of intermediate organizational structure based on long-term relationship between firms. The purpose of this book is to explain how interfirm relations contributed to their dynamics during the golden age of the semiconductor industry. Meanwhile this book clarifies the real source of dynamics in interfirm relations and how the firms have interacted. The author concludes that the competitive-cum-cooperative (CCC) interfirm interaction are observed. Quantitative and qualitative findings show that firms enjoy not only flexible cooperation based synergy effects, but also dynamics market-like effects by creating competition among partners through CCC interaction.

The scale and complexity of research and practices of open innovation mandate a correspondingly sophisticated form of decision making. Strategic Planning Decisions brings together a number of tools that ease the decision process in technology companies, providing both conceptual frameworks and practical applications.

Innovative approaches are presented such as an ontology-based model where all the relevant aspects of a potential technology are interrelated to provide a comprehensive and logically connected data pool for decision makers. Divided into two sections, Strategic Planning Decisions describe both strategic approaches using the decision tools, and tactical approaches. Some of these tools are expanded while some others are embedded in a model that will lay the ground for practical application. These include:

bibliometric analysis,
ontology,
roadmapping,
lead user, six sigma, and
multi-actor & multi-objective decision making methods

Recent research and relevant theory are balanced with up to date practical applications and hands on techniques making Strategic Planning Decisions ideal for engineers who wish to keep up to date with current ideas in the field of TM. It also provides workable methods for practising managers from all levels who wish to apply a more rigorous approach in their work and consultants concerned with technology assessment and its management."

These conference proceedings provide a comprehensive overview of and in-depth technical information on all possible bioenergy resources (solid, liquid, and gaseous), including cutting-edge themes such as advanced fuels and biogas. The book includes current state-of-the-art topics ranging from feedstocks and cost-effective conversion processes to biofuels economic analysis and environmental policy, and features case studies and quizzes for each section derived from the implementation of actual hands-on biofuel projects to aid learning. It offers readers a starting point on this challenging and exciting path. The central concepts are defined and explained in the context of process applications under various topics. By focussing on the pertinent fundamental principles in the environment and energy sciences and by repeatedly emphasizing the importance of their correlation, it offers a strong foundation for future study and practice. Learning about fundamental properties and mechanisms on an ongoing basis is absolutely essential for long-term professional viability in a technically vibrant area such as nanotechnology. The book has been written for undergraduate and graduate students in chemical, energy and environment engineering. However, selected sections can provide the basis for courses in civil, mechanical or electrical engineering. It includes a self-contained presentation of the key concepts of energy resources, solar thermal and photovoltaic systems, nuclear energy, biomass conversion technology and agricultural-waste processing. Throughout it interweaves descriptive material on sustainable development, clean coal technology, green technology, solid-waste management and lifecycle assessments. It offers an introduction to these topics rather than comprehensive coverage of the themes and their in-depth fundamentals.

By the year 2000, annual sales of computer products to China may well reach $15-18 billion, making China one of the largest computer markets in the world. At the same time, China's own computer industry is expected to become world-class and internationally competitive. How this will come about, the market and economic trends that are presently developing, and the opportunities they present for Western businesses are explored here by two insiders, offering not only useful analysis but hands-on guidance to the ways in which China's computer market works. With an appendix listing more than 500 of the most important Chinese computer companies, industrial and professional organizations, and related consulting and law firms, the book will be essential reading for computer industry management and top sales executives, and for investment bankers and others with important stakes in the China market.

China's computer market is not easy to enter. The key to doing so, according to the authors, is to understand not only China's unique historical, cultural, and environmental factors that condition the way business is done there, but the way Chinese businesspeople think and act. China is a low-income and transitional economy, much different from Japanese and other Asian economies, and incentives and price structures are distorted and the rules of the game are not clearly written. The legal infrastructure is incomplete, and laws are not rigorously enforced. Using the latest data available only from local Chinese sources, Zhang and Wang dissect the Chinese computer market in terms that Westerners can understand and relate to: its opportunities, but also its risks. Academics teaching and studying international business, marketing, and investment will also benefit from the authors' insights.

In this study, labor economist Henry Schechter concludes that there is a need for greater international prohibitions and for keeping open channels for collective bargaining for higher wages. He presents an analysis of recent changes in the United States and elsewhere, highlighting the spread of automated production technology to lesser developed, low-wage areas of the world, which leads to global demand-supply imbalances and downward pressure on wages. This circumstance, he charges, is aggravated as multinational corporations affiliate with one another, lessening competition and increasing monopolistic influences worldwide. This work will be of interest to the scholars and policymakers in academia, government, business, and the labor movement concerned with fiscal and labor economic policies.

From analyzing competition and identifying market segments, to capitalizing on Internet marketing opportunities and creating valuable after-sale services, this practical text aims to help the reader to apply marketing principles to foster success in the international market-place. It teaches how to objectively evaluate and manage their company's technological and knowledge-based competencies, develop effective product and pricing strategies, more precisely target their marketing efforts and utilize up-to-date distribution and sales channels. Also included is an investigation into the most effective positioning of the marketing department within the organization and a step-by-step guide to writing a strategic marketing plan.

This study was motivated by an awareness of the ever-growing importance of technology on productivity and power in the information age. It examines the relationship among national security, economic competition, and technology. An underlying premise is that in an era of diminished military confrontation, economic and technological power are acquiring enhanced importance in national security considerations. Green believes that this is bound to promote closer coordination between government and private industry, but not without tensions. Using both a public policy and an economic focus, his work seeks to clarify the debate on high technology industrial policy and to address the policy question of whether and how government should respond to competitive assaults in strategic industries.

This book is open access under a CC BY licence. Recent reductions in public funding for audiovisual products have led to dramatic changes in the industry. The lack of interaction between the industry and capital markets has made sourcing funds for audiovisual products especially difficult. This book explains why the distance between the audiovisual and financial markets exists, and considers the perspective of both audiovisual companies and financial intermediaries. Providing a thorough overview of the audiovisual industry in three major categories (television, cinema and web), it analyses the financing behind each. The author adapts the traditional assessment methods to include exploitation rights, distribution deals and risk determinants ; he also proposes a pricing model for the audiovisual products demonstrating that prices and values in a industry of prototype goods do not depend solely on cost and revenue. The book also includes a methodology for analysing the economics of the sector, the different sales agreements between broadcasters and the distribution deals between distributors and independent producers. Finally, a description of the main financial products for private finance is provided, as well as an explanation of how public funds can act as leverage to catalyze private resources through the use of guarantee funds. In The Economics of the Audiovisual Industry the author suggests that rather than relying on subsidized public support, the audiovisual industry should foster private-public partnerships and market dynamics to promote an alternative funding model based on a profitable and long-lasting connection between the audiovisual and financial markets. The valuation model, both for products and firms, proposed in this book are at the basis of this new approach.

Founded in 1987 by a former engineer in China's People's Liberation Army (Ren Zhengfei), Huawei Technologies is the world's largest telecoms equipment manufacturer and second only to Apple in smartphones. Its emergence into a multinational with over 175,000 employees all around the world is nothing short of extraordinary. This book delves into the financial workings and systems within Huawei - and the individuals whose craftsmanship and excellence enabled Huawei to expand globally in such impressive terms. Their personal stories tell us about the extraordinary vision, dedication, and perseverance required for companies to establish a robust financial system that supports the growth of a world-class company. Huawei's goal is not just to have profitable income and healthy cash flow. More important is that operating results are sustainable.

How did Japanese companies, technology-supporting organizations, and governments reformulate organizational strategies, industrial structures, and institutions to revive Japanese high-tech industries (semiconductor, telecommunications, and biotechnology) in the 1990s? This book takes a comprehensive look at the question by integrating the fields of institutional economics and corporate strategy, an approach that will be of significant interest theoretically and empirically to scholars, professionals, and graduate students. Complex interactions among diverse technology-related actors are presented, focusing on co-evolution among market changes induced by technology innovation, macro-level institutional arrangements for innovation, and corporate strategies for survival. Insights are provided on diverse types of institutional arrangements, technology innovation policies, and management practices for companies and technology organizations.

"The semiconductor industry is at the forefront of current tensions over international trade and investment in high technology industries. This book traces the struggle between U.S. and Japanese semiconductor producers from its origins in the 1950s to the novel experiment with ""managed trade"" embodied in the U.S.-Japan Semiconductor Trade Arrangements of 1986, and the current debate over continuation of elements of that agreement. Flamm provides a thorough analysis of this experiment and its consequences for U.S. semiconductor producers and users, and presents extensive discussion of patterns of competition within the semiconductor industry. Using a wealth of new data, he argues that a fundamentally new trade regime for high technology industries is needed to escape from the present impasse. He lays out the alternatives, from laissez-faire to managed trade, and argues strongly for a new set of international ground rules to regulate acceptable behavior by government and firms in high-tech industries. Flamm's detailed analysis of competition within the semiconductor industry will be of great value to those interested in the industrial organization of high-technology industries, as well as those concerned with trade and technology policy, international competition, and Japanese industrial policies. "

The Growth of Chinese Electronics Firms outlines the way firms grow in China at an organizational level. Kimura uses China's electronics industry as a case study for measuring technology-fuelled growth and provides a way to understand diversified the growth process systematically.

Based on in-depth study of the electronics giant Philips, Corporate Strategy, Public
Policy and New Technologies examines the key factors which have determined the
success or failure of new technologies and the global competitiveness of firms within a major
European consumer industry. Drawing on the insights gained from intensive empirical
research into the company's growth, structure and competitive strategy, the book traces the
reciprocal influences of Philips and of European Community policymaking on each other and
on the development of the industry since the 1970s.

The core of the book focuses on
detailed case studies of three major technological initiatives, and analyses the reasons for
their success or failure: the European VCR (Video Cassette Recorder) industry and Philips'
VCR 2000 format; Philips and the development of the European HDTV (High Definition
Television) system; and Philips' CD-i (Compact Disc-interactive) project. All three studies
raise important issues of competition, collaboration, technology and the role of public policy,
with a firm theoretical grounding in the most relevant and up-to-date academic
research.

In addition to providing an instructive analysis of the performance of an industry
at the levels of the firm, the state and the European Community, the book emphasises that the
strategies and policies discussed were adopted largely in response to the global challenge
from the USA and, above all, Japan.