High-Tech Ventures is for those who design, build, and market innovative products,people who are creating the high-tech world of the future. More specifically it is for all engineers, engineering managers, entrepreneurs, and intrapreneurs. Although engineers are responsible for identifying products and businesses that might benefit their company, all too often their suggestions are rejected. The products don't fit within the current business, or they threaten the status quo. Thus, start-up companies are the main arena for innovation.Entrepreneurs who are considering starting up a company, or who are already doing so, can use this book to determine the health of their venture. With High-Tech Ventures they can systematically assess the exact stages of their company's growth. They can compare their experiences to an ideal model, and sidestep,or eliminate,flaws early enough to save time, money, and even the company itself. High-Tech Ventures provides entrepreneurs with insight into the problems they may face, as well as a formal checklist for measuring success. It is also useful for board members, investors, and service industry personnel who are intimately involved in ventures. Professionals such as attorneys, accountants, technical consultants, and marketing consultants, who support the venture's infrastructure will also find critical information here. High-Tech Ventures includes revealing case studies from major entrepreneurial players such as Sun Microsystems, Apollo, Prime, Amdahl, Cullinet, etc.

Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms provides a comprehensive introduction to the state-of-the-art micro and nano systems that have recently been developed and applied to biophysical studies of cells and small organisms. These micro and nano systems span from microelectromechanical systems (MEMS) and microfluidic devices to robotic micro-nanomanipulation systems. These biophysical studies range from cell mechanics to the neural science of worms and Drosophila. This book will help readers understand the fundamentals surrounding the development of these tools and teach them the most recent advances in cellular and organismal biophysics enabled by these technologies.

In this thoroughly updated second edition, Matthias Herdegen provides a comprehensive and contemporary assessment of the regulation of biotechnology processes and products from an international and comparative perspective, complete with analysis of intricate legal and ethical debates. Considering recent advances in biotechnology, this new edition explores how regulatory approaches to controversial issues such as stem cell research, cloning and gene therapy differ across jurisdictions due to conflicting values and risk perceptions. Reflecting on current developments, the book explores the interaction between biotechnology and different fields of law, including: human rights, intellectual property, trade law and environmental law. In doing so, Herdegen investigates complex concerns such as balancing commercial interests with socio-cultural considerations and ensuring respect for human dignity in the pursuit of biomedical research. Furthermore this new edition includes examination of recent developments in areas such as genome editing, biomedicine, COVID-19 vaccines, and patents on essentially biological products, with an entirely revised section on biobanks. Providing a concise and accessible guide to a complex field of international law, this book will be of great value to those researching the law and regulation of biotechnology, biomedicine and biodiversity both within the EU and at an international level. Practicing lawyers will also benefit from a diverse array of sources from a range of legal systems.

Master the design and operation of perfusion cell cultures with this authoritative reference. Discover the current state-of-the-art in the design and operation of continuous bioreactors, with emphasis on mammalian cell cultures for producing therapeutic proteins. Topics include the current market for recombinant therapeutic proteins, current industry challenges and the potential contribution of continuous manufacturing. Provides coverage of every step of process development and reactor operation, including small scale screening to lab-scale and scale-up to manufacturing scale. Illustrated through real-life case studies, this is a perfect resource for groups active in the cell culture field, as well as graduate students in areas such as chemical engineering, biotechnology, chemistry and biology, and to those in the pharmaceutical industry, particularly biopharma, biotechnology and food or agro industry.

The Electronic Health Record: Ethical Considerations analyses the ethical issues that surround the construction, maintenance, storage, use, linkage, manipulation and communication of electronic health records. Its purpose is to provide ethical guidance to formulate and implement policies at the local, national and global level, and to provide the basis for global certification in health information ethics. Electronic health records (EHRs) are increasingly replacing the use of paper-based records in the delivery of health care. They are integral to providing eHealth, telehealth, mHealth and pHealth - all of which are increasingly replacing direct and personal physician-patient interaction - as well as in the developing field of artificial intelligence and expert systems in health care. The book supplements considerations that are raised by national and international regulations dealing with electronic records in general, for instance the General Data Protection Regulation of the European Union. This book is a valuable resource for physicians, health care administrators and workers, IT service providers and several members of biomedical field who are interested in learning more about how to ethically manage health data.

Rapid advances in the life sciences means that there is now a far more detailed understanding of biological systems on the cellular, molecular and genetic levels. Sited at the intersection between the life sciences, the engineering sciences and the design sciences, innovations in the biomaterials industry are expected to garner increasing attention and play a key role in future development. This book examines the biomaterials innovations taking place in corporations and in academic research settings today.Biomaterials Innovation offers a comprehensive overview of life science innovation and presents empirical research in the field of biomaterials innovation. Alexander Styhre examines innovation management practices in the field of biomaterials development and explains institutional changes in the biomaterials industry. The demand for accomplishing biocompatibility between the human body and the materials developed is highlighted, as is the relationship between financial markets and biomaterials companies. Finally, the author discusses the therapeutic, regulatory and managerial implications of biomaterials innovation. Biomaterials Innovation will be required reading for any researcher, policy-maker or student interested in innovation management, the life sciences and the development of health care therapies. Contents: 1. Life and Materiality, Nature and Artifice: Transgressing the Divide 2. Bios, Materiality, and Biomateriality 3. Innovation Management and Innovation in the Life Sciences 4. Shifting Institutional Logics in Biomaterial Companies 5. The Epistemology of Biomaterials: How Biomaterials Become Embodied 6. Financing Biomaterials Innovation: Selling Science in Venture Capital Markets 7. Biomaterials Innovation: Re-creating the Human Body Appendix: Methodology of the Studies Bibliography Index

Within less than a decade, during the 1990s, the state of Israel established its global high tech sector. The number of startups rose to almost 3,000. Total venture capital available reached approximately $ 3 billion. Israeli firms trading on NASDAQ climbed to 120 with aggregate market value of approximately $120 billion, twice the Israeli GNP.
This book emphasizes the multilevel nature of this development from a strategic management perspective. The first level focuses at the country global processes emphasizing the entry of foreign multinational corporations and the privatization of state owned enterprises. The second level focuses on the government and its role in establishing the technological incubators and venture capital industries. The third level focuses on the sources of new start ups and the role of veterans of elite technological units of Israel Defense Forces and women entrepreneurs. The fourth level focuses on the emerging organizations and the role of the board of directors and competitive intelligence capabilities and practices. Finally, the fifth level focuses at the industry level, emphasizing the role of the large number of new firms in creating new industrial sectors. The multilevel paradigm describes the sequential effects, starting at the first global level, and the interactive effects, across all five levels.
The book provides insights that can aid academic researchers, company executives and public policy makers in understanding high tech takeoff. It is especially interesting and important given the turbulent environment mixed with the optimism of the peace process of Israel in the Middle East during the 1990s.
*An aid for academic researchers, publicpolicy makers, and company executives for understanding high tech takeoff
*Conceptualizes the success of Israeli high-tech as a multilevel operation consisting of global, governmental, sources of new start ups, organizational, and industrial factors
*Discusses each of these factors individually and the interaction between them

The economic boom of the 1990s that led to the rapid rise of computer hardware and software companies (on both sides of the Pacific Rim) also led to the rise of a trans-Pacific commuter culture, a culture in which thousands of Taiwanese-born high-tech engineers realized that they could greatly increase their career opportunities by establishing a life-style that allowed them and their families to regularly commute between two hornes, one in Silicon Valley and the other in Taiwan. The Global Silicon Valley Home takes a close look at how participants in the jet-set, wired-to-the-Net, trans-Pacific commuter culture have invented new ways of thinking about how their homes reflect their personal identities.

The scale and complexity of research and practices of open innovation mandate a correspondingly sophisticated form of decision making. Strategic Planning Decisions brings together a number of tools that ease the decision process in technology companies, providing both conceptual frameworks and practical applications. Innovative approaches are presented such as an ontology-based model where all the relevant aspects of a potential technology are interrelated to provide a comprehensive and logically connected data pool for decision makers. Divided into two sections, Strategic Planning Decisions describe both strategic approaches using the decision tools, and tactical approaches. Some of these tools are expanded while some others are embedded in a model that will lay the ground for practical application. These include: bibliometric analysis, ontology, roadmapping, lead user, six sigma, and multi-actor & multi-objective decision making methods Recent research and relevant theory are balanced with up-to-date practical applications and hands-on techniques making Strategic Planning Decisions ideal for engineers who wish to keep up-to-date with current ideas in the field of TM. It also provides workable methods for practising managers from all levels who wish to apply a more rigorous approach in their work and consultants concerned with technology assessment and its management.

Ever since Schumpeter's groundbreaking work there has been a plethora of new research seeking to extend the direction and dynamics of innovation. Using a rich account of detailed interviews, this book offers new evidence on how latecomers have successfully caught up and leapfrogged incumbent firms. Catching Up and Leapfrogging: the new latecomers in the integrated circuits industry explores how technological transitions affect latecomer catch-up strategies, and vice versa, in a high technology industry. It looks to the East Asian latecomers who, towards the end of the twentieth century, pioneered a new pathway through organizational change by specializing in the key production stages of integrated circuits and pushing technologies further. This volume assesses how latecomer resource acquisition strategies have varied alongside structural industry changes and evaluates the mechanisms through which firms started life as technology followers and rose to become technology leaders. Xiao-Shan Yap and Rajah Rasiah present a unique story about how firm strategies evolve from the catching up phase to the leapfrogging phase, captured from the accounts of managers on the ground. It is the first time firm-level strategies have been systematically analysed to describe twenty-first century strategic management in the integrated circuits industry in particular, and the high tech industry in general. The evidence and analysis in this book offers insights for chief executive officers, policy-makers and researchers to revisit existing approaches to the theory of catching up and leapfrogging.

Over the last fifty-plus years, the increased complexity and speed of integrated circuits have radically changed our world. Today, semiconductor manufacturing is perhaps the most important segment of the global manufacturing sector. As the semiconductor industry has become more competitive, improving planning and control has become a key factor for business success. This book is devoted to production planning and control problems in semiconductor wafer fabrication facilities. It is the first book that takes a comprehensive look at the role of modeling, analysis, and related information systems for such manufacturing systems. The book provides an operations research- and computer science-based introduction into this important field of semiconductor manufacturing-related research.

Scientists in the biotechnology sector have developed a vast array of products and procedures, including drugs, diagnostics, agricultural products and veterinary procedures. This is made possible through various intra- and inter-organizational collaborations between the academic and private sectors, and through the establishment of networks for learning. In Networks for Learning and Knowledge Creation in Biotechnology, Amalya Lumerman Oliver shows how, in many respects, the organizational structure of the industry parallels one of its most important innovations - recombinant DNA (rDNA). She shows how the concept of recombination can be used to explain a number of organizational elements, including biotechnology firms, the form of university-based spin-offs, scientific entrepreneurship, and trust and contracts in learning collaborations and networks. The result is a stimulating account of how multiple theoretical perspectives can be used to understand the structure of the biotechnology industry.

The comprehensive, practical guide to buying, selling, and merging technology companies

The Technology M&A Guidebook provides executives and entrepreneurs interested in acquiring or selling a technology company with everything they need to know about the entire M&A process, from identifying target companies or buyers to financial analysis, due diligence, tax issues, valuation, and legal considerations.

This book explores specific issues that are unique to technology M&A: assessing the impact of technology sector high-change rates; market-driven product development; company culture issues; engineers as managers and managers as engineers; consumer and technical product differences; technology marketing issues; intellectual property considerations; Internet interaction; and more. It also provides detailed analyses of factors involved in acquiring companies from different sectors, including:

• Semiconductor equipment and chip manufacturers
• PC/workstation and related hardware companies
• Software businesses
• Data networking and telecommunications firms
• Internet-related companies

Don’t enter the M&A process unprepared. Let The Technology M&A Guidebook help you beat the odds and make your sale or acquisition a complete success.

This is a full-length history of the Western Electric Company, which was the manufacturing arm of the Bell System. As manufacturer in the communications revolutions in the nineteenth and twentieth centuries, Western Electric made products that accelerated society's pace, such as telegraphs, telephones, an early computing machine, radios, radar and transistors. Western's history offers numerous examples of the difference between innovation and implementation. The aftermath of Western's 1882 acquisition by Bell Telephone, for instance, reveals vertical integration as a lengthy process rather than a single event. Ironically, although Western transformed business worldwide with innovations in areas such as quality control and industrial psychology, the company was slow to implement these innovations itself. Western's dual role as captive supplier for a regulated monopoly and as government contractor led to its most rapid change, in the area of civil rights.

At present, human society is facing a health care crisis that is affecting patients worldwide. In the United States, it is generally believed that the major problem is lack of affordable access to health care (i.e. health insurance). This book takes an unprecedented approach to address this issue by proposing that the major problem is not lack of affordable access to health care per se, but lack of access to better, safer, and more affordable medicines. The latter problem is present not only in the United States and the developing world but also in countries with socialized health care systems, such as Europe and the rest of the industrialized world. This book provides a comparative analysis of the health care systems throughout the world and also examines the biotechnology and pharmaceutical industries.

Examines the health care structure of the United States, Europe, and the third world, both separately and comparativelyOffers primary source insight through in-depth interviews with pharmaceutical and health care industry leaders from around the worldCarefully explains, in clear terms, the intricacies of the health care and pharmaceutical system and how these intricacies have led to the current crisisOffers concrete, comprehensive solutions to the health care crisis

It is an old adage that "fortune favours the prepared mind", that in many cases the elements of a creativity synthesis just "happened to be there".  It is Koepp's valuable contribution that he assembles all such clustering dynamics and makes coherent "the gale of creativity destruction" that has puzzled us all.  An innovative book for an innovative topic.  Dr Charles Hampden-Turner, Cambridge University

Every so often one is lucky enough to be at the center of the world while it still is the center of the world.  Being in Silicon Valley during the 1990s was certainly just that.  Such centers produce a flowering of creativity that can only occur when the air becomes so turbulent that ideas, which in normal times would just be fleeting fantasies, get up and fly.  Clusters of Creativity captures this anti-gravitational feeling perfectly.  Rich Gold, Former Director of RED, Xerox PARC

With over 30,000 employees worldwide and products that range from refrigerators to cell phones, Haier is the largest consumer electronics manufacturer in China. This book traces this giant's path to success, from its early bleak years when the company director had to beg from the neighboring village head for money to pay bonuses to his employees to its achievement of placing sixth on Forbes Global's worldwide household appliance manufacturer in 2001. Much emphasis is given to Zhang Ruimin, Haier's chairman and CEO, for his pivotal role in the company's success. Explained is how Haier excelled where many other Chinese companies did not: a commitment to quality, service, and technology innovation, in addition to a global vision and a management style that is a blend of Jack Welch and Confucius.

A New York Times bestseller.

Winner of the Financial Times/McKinsey Business Book of the Year Award.

'Chilling . . . Reads like a West Coast version of All the President’s Men.' New York Times Book Review

The full inside story of the breathtaking rise and shocking collapse of Theranos, the multibillion-dollar biotech startup, by the prize-winning journalist who first broke the story and pursued it to the end, despite pressure from its charismatic CEO and threats by her lawyers.

In 2014, Theranos founder and CEO Elizabeth Holmes was widely seen as the female Steve Jobs: a brilliant Stanford dropout whose startup "unicorn" promised to revolutionize the medical industry with a machine that would make blood testing significantly faster and easier. Backed by investors such as Larry Ellison and Tim Draper, Theranos sold shares in a fundraising round that valued the company at more than $9 billion, putting Holmes's worth at an estimated $4.7 billion. There was just one problem: The technology didn't work.

In Bad Blood, John Carreyrou tells the riveting story of the biggest corporate fraud since Enron, a tale of ambition and hubris set amid the bold promises of Silicon Valley.

Now to be adapted into a film, with Jennifer Lawrence to star.

Manufacturing the Future: A History of Western Electric is the first full-length history of the Western Electric Company, the manufacturing arm of the Bell System. As a manufacturer in the communications revolutions in the nineteenth and twentieth centuries, Western Electric made new products such as telegraphs, telephones, an early computing machine, radios, radar, and transistors. The book demonstrates, through Western's 1882 acquisition by Bell Telephone, that vertical integration was a lengthy process rather than a single event. It also shows the coming of age of industrial psychology and describes the advent of civil rights in corporate America.

New Horizons in Natural Compound Research provides the latest updates in natural compound research (plant, microbes, algae, fungi) and their novel applications in health, agriculture and environment. The book gives recent advances in the extraction of natural compounds, cutting-edge approaches for natural compound purifications, and emerging trends in natural compound screening and identification. In addition, it provides a detailed explanation of the databases and libraries of natural compounds, as well as their significance. Sections focus on research and multidisciplinary practical techniques of natural product research, encouraging young scientists to pursue unique research while also generating strong research ideas. From a future perspective, this book acts as a guide to identify potential areas and new research opportunities in the field of natural products and their service towards human beings, animals and the environment.

There are 17 million small and medium-sized enterprises (SMEs) in the European Union which play an important role in economic life. Within this subset, increasing recognition is being given to "new technology-based ftrms. " 1 In the literature, different defmitions have been put forward to describe the term new technology-based ftrm (Oakey et a11988; Roberts 1991; Autio 1995; Storey and Tether 1998). Common denominators include that the activity is based on the exploitation of advanced technological know-how, the prior affiliation of founders with research establishments and the entrepreneurial character of the ftrm. Research studies in Europe, North America and the Paciftc Rim have identifted these ftrms' important contributions in new employment creation, export sales growth, product and process innovation and structural adjustment (e. g. Rothwell & Zegveld 1982; OECD 1986; Oakey et a11988; Acs & Audretsch 1991; Roberts 1991; Coopers & Lybrand 1996). While there is a growing body of literature on new technology-based ftrms that concentrates on strategic issues such as access to fmancial resources, growth processes and innovation behaviour (see Storey and Tether 1998, for a review), there has been relatively little research into the process by which young high technology companies have internationalised. Research activity in the latter fteld has historically been strongly oriented towards large ftrms or, more rarely, towards "traditional transnational SMEs" in the manufacturing sector that often act as suppliers of bigger ftrms and are characterised by simple production technologies and low-technology products (United Nations 1993)."

Biotechnology is a field that inspires complex legal and ethical debates on an international scale. Taking a fresh approach to the subject, Matthias Herdegen provides a comprehensive assessment of the regulation of biotechnology processes and products from an international and comparative perspective. Herdegen explores how regulatory approaches to controversial issues such as: stem cell research and cloning and gene therapy differ across jurisdictions due to conflicting values and risk perceptions. The book goes on to examine how international regulatory instruments aim to address these conflicting perspectives and provide judgments based on broad international consensus. Chapters explore the interaction between biotechnology and different fields of law including: human rights, intellectual property, trade law and environmental law. In doing so, a number of complex issues are raised such as the need to balance commercial interests with socio-cultural considerations and the need to ensure respect for human dignity in the pursuit of biomedical research. Providing a concise and accessible guide to a complex field of international law, this book will be of great value to those researching the law and regulation of biotechnology, biomedicine and biodiversity both within the EU and on an international scale. The book will also be a useful resource for practicing lawyers as it includes sources from a diverse range of legal systems and analyses relevant decisions by international adjudicatory bodies.

The life sciences is an industrial sector that covers the development of biological products and the use of biological processes in the production of goods, services and energy. This sector is frequently presented as a major opportunity for policy-makers to upgrade and renew regional economies, leading to social and economic development through support for high-tech innovation. Innovation, Regional Development and the Life Sciences analyses where innovation happens in the life sciences, why it happens in those places, and what this means for regional development policies and strategies. Focusing on the UK and Europe, its arguments are relevant to a variety of countries and regions pursuing high-tech innovation and development policies. The book's theoretical approach incorporates diverse geographies (e.g. global, national and regional) and political-economic forces (e.g. discourses, governance and finance) in order to understand where innovation happens in the life sciences, where and how value circulates in the life sciences, and who captures the value produced in life sciences innovation. This book will be of interest to researchers, students and policy-makers dealing with regional/local economic development.

Japan is an example of what is known as a "latecomer" in industrial development. Drawing on case studies of computer and telecommunications and related firms, Donna Doane investigates how intra- and inter-industry cooperation between public and private enterprises pushed rapid technological advancement in Japan. The book places such interlinkage in the context of a historical evolution, starting with prewar industrial house groupings that helped link indigenous and external ideas and form an integrated technological base.Doane focuses mainly on the postwar, catch-up period from the 1960s through the 1980s in which three characteristics associated with late development are examined: multistructured industry, family-based industrial networks, and a distinct government-industry relationship. Implications of the cooperative structure are drawn for other advanced industrial as well as developing countries, where flexible technological networks could help individual enterprises overcome the limitations of isolated organization to survive rapid economic changes.

Technology-based firms contribute to dynamic competition, ensure product variety, close market gaps and promote job creation. Their development is impeded by a difficult access to capital, high R&D costs and management deficits. The book analyses their chances and risks in the innovation process. Topics deal with the management of technology-based firms, different aspects on their financing, the spectrum of public promotion programmes and the venture capital market in Germany. Finally, the book centres on regional technology and economic promotion and the creation of regional networks for technology-based firms. The reader documents research of Fraunhofer-ISI on technology-based firms and their environment and aims at a better understanding of specific chances and risks in the development process of such firms.