The aim of this study is to investigate in the role of Venture Capital in the development of New Technology Based Firms in two countries: USA and Germany. Based on literature review and empirical work issues concerning the extent and stage of financing, the nature of oversight provided by Venture Capitalists and the framework conditions for Venture Capital are subject of investigation. The results have been reflected in a workshop with experts from research, industry and policy.

The COVID-19 pandemic has affected the entire world in an unprecedented way since 2019. However, novel and innovative applications of various omics, computational, and smart technologies have helped manage the pandemic of the 21st century in a very effective manner. Omics approaches and technologies in COVID-19 presents up-to-date knowledge on omics, genetic engineering, mathematical and computational approaches, and advanced technologies in the diagnosis, prevention, monitoring, and management of COVID-19. This book contains 26 chapters written by academic and industry experts from more than 15 countries. Split into three sections (Omics; Artificial Intelligence and Bioinformatics; and Smart and Emerging Technologies), it brings an overview of novel technologies under omics such as, genomic, metagenomic, pangenomic, metabolomics and proteomics in COVID-19. In addition, it discusses hostpathogen interactions and interactomics, management options, application of genetic engineering, mathematical modeling and simulations, systems biology, and bioinformatics approaches in COVID-19 drug discovery and vaccine development. This is a valuable resource for students, biotechnologists, bioinformaticians, virologists, clinicians, and pharmaceutical, biomedical, and healthcare industry people who want to understand the promising omics and other technologies used in combating COVID-19 from various aspects.

The incredible progress in microelectronics over the last 20 years has led to a whole range of products that have invaded and often reshaped our lives. Technologies currently being deployed or in the laboratory, such as the information super highway, virtual reality, instantaneous language translators and artificial nerves promise to further revolutionise our lives. This book, written by a distinguished member of the microelectronics community in collaboration with a leading journalist, seeks to bridge the gap between the microelectronics community and the general public. The evolution of the technology is explained with its social and economic effects, showing the forces shaping the industry and concluding with a glimpse of the ideas currently under development in the worlds' electronics laboratories.

"Free as in Freedom" interweaves biographical snapshots of GNU project founder Richard Stallman with the political, social and economic history of the free software movement. It examines Stallman's unique personality and how that personality has been at turns a driving force and a drawback in terms of the movement's overall success.

"Free as in Freedom" examines one man's 20-year attempt to codify and communicate the ethics of 1970s era "hacking" culture in such a way that later generations might easily share and build upon the knowledge of their computing forebears. The book documents Stallman's personal evolution from teenage misfit to prescient adult hacker to political leader and examines how that evolution has shaped the free software movement. Like Alan Greenspan in the financial sector, Richard Stallman has assumed the role of tribal elder within the hacking community, a community that bills itself as anarchic and averse to central leadership or authority. How did this paradox come about? "Free as in Freedom" provides an answer. It also looks at how the latest twists and turns in the software marketplace have diminished Stallman's leadership role in some areas while augmenting it in others.

Finally, "Free as in Freedom" examines both Stallman and the free software movement from historical viewpoint. Will future generations see Stallman as a genius or crackpot? The answer to that question depends partly on which side of the free software debate the reader currently stands and partly upon the reader's own outlook for the future. 100 years from now, when terms such as "computer," "operating system" and perhaps even "software" itself seem hopelessly quaint, will Richard Stallman's particular vision of freedom still resonate, or will it have taken its place alongside other utopian concepts on the 'ash-heap of history?'

Novel AI and Data Science Advancements for Sustainability in the Era of COVID-19 discusses how the role of recent technologies applied to health settings can help fight virus outbreaks. Moreover, it provides guidelines on how governments and institutions should prepare and quickly respond to drastic situations using technology to support their communities in order to maintain life and functional as efficiently as possible. The book discusses topics such as AI-driven histopathology analysis for COVID-19 diagnosis, bioinformatics for subtype rational drug design, deep learning-based treatment evaluation and outcome prediction, sensor informatics for monitoring infected patients, and machine learning for tracking and prediction models. In addition, the book presents AI solutions for hospital management during an epidemic or pandemic, along with real-world solutions and case studies of successful measures to support different types of communities. This is a valuable source for medical informaticians, bioinformaticians, clinicians and other healthcare workers and researchers who are interested in learning more on how recently developed technologies can help us fight and minimize the effects of global pandemics.

The life sciences is an industrial sector that covers the development of biological products and the use of biological processes in the production of goods, services and energy. This sector is frequently presented as a major opportunity for policy-makers to upgrade and renew regional economies, leading to social and economic development through support for high-tech innovation. Innovation, Regional Development and the Life Sciences analyses where innovation happens in the life sciences, why it happens in those places, and what this means for regional development policies and strategies. Focusing on the UK and Europe, its arguments are relevant to a variety of countries and regions pursuing high-tech innovation and development policies. The book's theoretical approach incorporates diverse geographies (e.g. global, national and regional) and political-economic forces (e.g. discourses, governance and finance) in order to understand where innovation happens in the life sciences, where and how value circulates in the life sciences, and who captures the value produced in life sciences innovation. This book will be of interest to researchers, students and policy-makers dealing with regional/local economic development.

Biomedical Innovations to Combat COVID-19 provides an updated overview on the development of vaccines, antiviral drugs and nanomaterials, and diagnostic methods for the fight against COVID-19. Perspectives on such technologies are identified, discussed, and enriched with figures for easy understanding and applicability. Furthermore, it contains basic aspects of virology, immunology, and antiviral drugs that are needed to fully appreciate these innovations. This book is split into four sections: introduction, presenting basic virologic and epidemiological aspects of COVID-19; vaccines against COVID-19, discussing their different types and applications used to develop them; diagnostic approaches for SARS-CoV-2, encompassing advanced sensing and microfluidic-based biosensors; and drug development and delivery, where antivirals based on nanomaterials or drugs are presented. It is a valuable source for virologists, biotechnologists, and members of biomedical field interested in learning more about how novel technologies can be applied to fasten the eradication of the COVID-19 and similar pandemics.

Bioinformatics for Everyone provides a brief overview on currently used technologies in the field of bioinformatics-interpreted as the application of information science to biology- including various online and offline bioinformatics tools and softwares. The book presents valuable knowledge in a simplified way to help students and researchers easily apply bioinformatics tools and approaches to their research and lab routines. Several protocols and case studies that can be reproduced by readers to suit their needs are also included.

Science is not a collection of facts. Science is the process by which we draw inferences from facts. Volume I of Logic and Critical Thinking in the Biomedical Sciences invites readers to linger over a collection of common observations to see what inferences can be drawn, when one applies a bit of deductive logic. If we just think about what we observe, it is often possible to discover profound biomedical insights. Volumes 1 and 2 of Logic and Critical Thinking in the Biomedical Sciences are written for biomedical scientists and college-level students engaged in any of the life sciences, including bioinformatics and related data sciences.

Everything you need to know about the most important trend in the history of the world

Within most people's lifetimes, the developments in the biotechnology sector will allow us to live increasingly long and healthy lives, as well as provide us with technological innovations that will transform the way we live. But these innovations offer more than just hope for a better life, but hope for better returns too. Financial returns of incredible magnitude await savvy investors and businesspeople who can see the massive changes on the horizon. This book details these fast-moving trends and innovations and offers extensive advice on how to profit from them in business and investing.

Masters of Doom is the true inside story of the Lennon and McCartney of the video game industry: John Carmack and John Romero. Together they created an empire, ruled a multibillion-dollar industry, and provoked a national controversy. They lived a unique American dream, escaping their broken homes to co-create the most innovative and notoriously successful video games in history - Doom and Quake - until the games they made tore them apart. David Kushner has been covering the video game industry for ten years and knows all the angles. Even those with no interest in video games will be fascinated by this vastly entertaining tale of friendship, betrayal and the genesis of a multibillion-dollar popular art form.

Single-Cell Omics: Volume 1: Technological Advances and Applications provides the latest technological developments and applications of single-cell technologies in the field of biomedicine. In the current era of precision medicine, the single-cell omics technology is highly promising due to its potential in diagnosis, prognosis and therapeutics. Sections in the book cover single-cell omics research and applications, diverse technologies applied in the topic, such as pangenomics, metabolomics, and multi-omics of single cells, data analysis, and several applications of single-cell omics within the biomedical field, for example in cancer, metabolic and neuro diseases, immunology, pharmacogenomics, personalized medicine and reproductive health. This book is a valuable source for bioinformaticians, molecular diagnostic researchers, clinicians and members of the biomedical field who are interested in understanding more about single-cell omics and its potential for research and diagnosis.

An authoritative collection of the leading critical and contemporary writings published in the field of technology and organizations, this set spans a key fifty-year period. The volumes take the reader from the first and most influential papers from the early 1950s, through to recent publications which address contemporary and emerging debates in the field at the dawn of a new century.
Each of the 4 volumes has a particular focus upon this key area of research and scholarship:
* the early debates
* theories, paradigms and concepts
* critical empirical studies
* emerging themes and future debates
The editors provide an original introduction to, and overview of, the themes, debates, perspectives, theories and paradigms which characterise this key area of organisation studies. An extensive index guides the reader through the four volumes.

This book provides cases and analyses of causes and consequences of difficulty in downsizing and exiting in the electronics industry during the "two lost decades" in Japan. Because of excess capacity in the industry, many electronics companies have been required for downsizing and exit since the 1990s. Exploiting corporate financial and segment datasets, it shows empirical evidence of misallocation of internal funds to "zombie" segments-intra-firm businesses suffering losses consecutively. The topics addressed in the book include the failure of Japanese corporate internal control systems, the lack of capital market pressure, employment protection, and misallocation of internal funds to businesses with few prospects. The last two decades indicate that the Japanese corporate governance systems have failed to resolve problems of excess capacity, as did US systems in the 1980s. Zombie lending is no more than one phase of the difficulty of downsizing and exit in response to excess capacity in the banking sector. Supported by both data analyses and rich anecdotal evidence, this book is highly recommended to readers who seek a convincing and comprehensive explanation of Japan's two lost decades from the points of view of difficulty in downsizing and exit. The authors' analyses have implications not only for accelerating downsizing and exit in corporate Japan, but also for the world economy.

Demand for cleanrooms is flourishing as manufacturing becomes increasingly sophisticated. From computers and CD players to medicines and convenience foods, more and more products require high levels of contamination control. Fully revised and updated, Cleanroom Design, Second Edition presents the latest advances in the field. Written by a highly experienced team of international authors, the broad coverage encompasses the design of cleanrooms for the microelectronics, pharmaceutical, medical device and biotechnology industries. Features include:

• New chapter on the design of medical devices featuring configurations for heart pacemakers and aortic bioprostheses
• Examination of the international standards for the design of cleanrooms providing the designer with a concise information source
• Discussion of cost-efficiency and energy-saving concepts such as minimizing the air flow rate and the impact of mini-environments
• Section on high efficiency air filtration looking at filter standards and testing
• Practical guidance on construction materials and surface finishes, pipework design, the production and transmission of high purity gases and water purification techniques

Despite what you may have read in the popular press and in social media, Precision Medicine is not devoted to finding unique treatments for individuals, based on analyzing their DNA. To the contrary, the goal of Precision Medicine is to find general treatments that are highly effective for large numbers of individuals who fall into precisely diagnosed groups. We now know that every disease develops over time, through a sequence of defined biological steps, and that these steps may differ among individuals, based on genetic and environmental conditions. We are currently developing rational therapies and preventive measures, based on our precise understanding of the steps leading to the clinical expression of diseases. Precision Medicine and the Reinvention of Human Disease explains the scientific breakthroughs that have changed the way that we understand diseases, and reveals how medical scientists are using this new knowledge to launch a medical revolution.

Originally published in 1988, this book explores how new technologies, industrial innovation and the growth of high technology industry have affected regional employment and economic change in different European countries. It discusses the factors which make some areas better suited than others to the development of the new industries, emphasising how fuctional integration and dependence upon highly-qualified manpower tend to concentrate these industries in particular locations. Attempts to encourage innovation and the development of high technology industry in old industrial areas are discussed, with particular reference to the role of large firms, training programmes and government policies.

This book, originally published in 1988, reviews the development of high technology industries at global and selected national and local levels, providing a unique insight into reasons for and consequences of such modern industrial development. It appraises government policies for assisting the development of this sector and focuses on the fact that high tech industry tends to be concentrated in particular regions of countries which attain the status of 'successful populations'. High technology industry seems to offer little benefit to declining manufacturing areas and the book offers explanations for these regional concentrations and assesses the likely consequences.

The sixth installment of the "Fisher Investments On" series is a comprehensive guide to understanding and analyzing investment opportunities within the Technology sector. "Fisher Investments on Technology" can help you quickly become familiar with this highly diversified sector, how the sector is segmented by industries, their respective macroeconomic drivers, and the challenges facing Technology firms.

This reliable guide skillfully addresses how to determine optimal times to invest in Technology stocks, and which industries and sub-industries have the potential to perform well in various environments. The global Technology sector is complex, including a variety of sub-industries and countries--each with their own unique characteristics. Using the framework found here, you'll discover how to identify these differences, spot opportunities, and avoid major pitfalls.

"Fisher Investments on Technology: " Discusses industry fundamentals, drivers, attributes, and potential challenges Addresses the challenges unique to Technology and some common pitfalls to avoid. Delves into top-down investment methodology as well as individual security analysis. Outlines a five-step process to help differentiate Technology firms--designed to help you identify ones that may have greatest probability of outperforming Provides investment strategies for a variety of market environments

Filled with in-depth insights and expert advice, "Fisher Investments on Technology" provides a framework for understanding this sector and its industries to help you make better investment decisions--now and in the future. With this book as your guide, you can gain a global perspective of the Technology sector and discover strategies to help achieve your investing goals.

In the fall of 1980, Genentech, Inc., a little-known California genetic engineering company, became the overnight darling of Wall Street, raising over $38 million in its initial public stock offering. Lacking marketed products or substantial profit, the firm nonetheless saw its share price escalate from $35 to $89 in the first few minutes of trading, at that point the largest gain in stock market history. Coming at a time of economic recession and declining technological competitiveness in the United States, the event provoked banner headlines and ignited a period of speculative frenzy over biotechnology as a revolutionary means for creating new and better kinds of pharmaceuticals, untold profit, and a possible solution to national economic malaise. Drawing from an unparalleled collection of interviews with early biotech players, Sally Smith Hughes offers the first book-length history of this pioneering company, depicting Genentech's improbable creation, precarious youth, and ascent to immense prosperity. Hughes provides intimate portraits of the people significant to Genentech's science and business, including cofounders Herbert Boyer and Robert Swanson, and in doing so sheds new light on how personality affects the growth of science. By placing Genentech's founders, followers, opponents, victims, and beneficiaries in context, Hughes also demonstrates how science interacts with commercial and legal interests and university research, and with government regulation, venture capital, and commercial profits. Integrating the scientific, the corporate, the contextual, and the personal, "Genentech" tells the story of biotechnology as it is not often told, as a risky and improbable entrepreneurial venture that had to overcome a number of powerful forces working against it.

Translational Biotechnology: A Journey from Laboratory to Clinics presents an integrative and multidisciplinary approach to biotechnology to help readers bridge the gaps between fundamental and functional research. The book provides state-of-the-art and integrative views of translational biotechnology by covering topics from basic concepts to novel methodologies. Topics discussed include biotechnology-based therapeutics, pathway and target discovery, biological therapeutic modalities, translational bioinformatics, and system and synthetic biology. Additional sections cover drug discovery, precision medicine and the socioeconomic impact of translational biotechnology. This book is valuable for bioinformaticians, biotechnologists, and members of the biomedical field who are interested in learning more about this promising field.

Smiths Group (formerly Smiths Industries), part of the UK FTSE 100 index, is a global engineering company with a market capitalisation over GBP5bn. Evolving from beginnings in the Victorian jewellery trade, to significant market presences in the twentieth century motor accessory, clock and watch industries, it has reinvented itself again as a diversified international company, operating in the medical, communications, security and engineered components sectors. Its narrative history, illuminating the reasons for its survival and adaptability, offers useful data and information to aid wider research into questions such as the legitimacy of conglomerates as a business model, the creation and maintenance of corporate culture, issues of succession, the effects of mergers and the questionable value placed upon targeted synergies-even the role of serendipity. The story begins with several generations of the Smith family amassing a fortune in retail, and then, following a 1914 stock-market flotation, describes the transition from family run business to the development of a professionally-run managerial enterprise. Since the 1970s it has had to face the decline of major markets and competitive pressures, leading to the adoption of new business lines, globalisation, and the internationalisation of its workforce. It now has 23,000 employees across more than 50 countries-along the way shocking the markets by abandoning core businesses and undergoing a controversial merger. Unfettered access to company records, and interviews with former staff members, provide insights into the strategy and management of the firm, illuminating the rich culture of Smiths, characterised by the frequent fostering of technical brilliance and a cast of larger than life characters.

Divided Sun is the story of the methods and machinations that have driven Japan's high-tech industrial policies over the last two turbulent decades. It focuses on MITI and Japan's giant electronics firms - their ambitions and conflicts - in the context of the core of MITI's high-tech strategy since the 1970's, the so-called "cooperative" technology consortia. The author finds that despite widespread claims to the contrary, MITI's industrial policy in high technology has proved to be neither cooperative nor successful. He shows that the policymaking process is torn by conflict and competition: between MITI and other bureaucracies, between MITI and powerful Japanese companies, and between the different companies. As a result, the elaborate structures created to promote cooperation are in many cases a public show masking the underlying reality of fierce competition and conflict.
Equally important is the fact that recent technologies emerging from Japanese high-tech consortia have been sadly disappointing. The author's detailed explanation of MITI's internal decisionmaking processes reveals that much of MITI's decline in effectiveness is caused by its rigid insistence on targeting technologies in accordance with long-term plans even when the technologies are soon rendered obsolete in the rapidly changing high-tech marketplace. In the shadow of these new realities, MITI finds itself at a turning point. The author argues that it will have to redefine itself and carve out a new role in the Japanese political economy and the bureaucracy. MITI's primary focus cannot be what once worked so successfully, i.e., the promotion of Japanese companies in international competition. If it does not find a new role, and soon, MITI faces a slow but inevitable decline in influence and effectiveness.

The influence of European Competition Law is global, and Competition Law and Regulation of Technology Markets takes a practical, integrated approach to competition law, which is becoming increasingly prominent in the technology sector in Europe - as demonstrated by a number of high profile cases such as Microsoft, Sony/BMG and Intel.
The book focuses on the information, communication and media markets that form the 'new economy'. It provides a coherent analysis of these various markets by considering the regulatory context, and by addressing the issues, and ensuing legal problems, that are common to them. These include; high fixed costs, the importance of intellectual property and standards, the impact of interoperability, and the prevalence of the network effect.
The book considers how EU competition rules interact with regulation, intellectual property law and data protection rules, and goes on to analyze the application of competition rules in four fields; communications networks, industrial intellectual property, creative intellectual property, and electronic commerce and services.. The book charts a clear path through this complex interaction of rules, and provides the competition law practitioner with the necessary tools to advise on legal problems in these sectors.

High-tech businesses form a crucial part of entrepreneurial activity in some ways representing very typical examples of entrepreneurship, yet in some ways representing quite different challenges. The uncertainty in innovation and advanced technology makes it difficult to use conventional economic planning models, and also means that the management skills used in this area must be more responsive to issues of risk, uncertainty and evaluation than in conventional business opportunities.
While entrepreneurial courses do reflect the importance of high-tech businesses, they often lack the resources needed to teach this in a way that goes beyond standard how to start up a business courses whilst not focusing solely on theoretical models. This book specifically focuses on the mix of theory and practice needed to accurately inform students. Key topics covered include:
* uncertainty and innovation
* entrepreneurial finance
* marketing technological innovations
* high-tech incubation management.
Including case studies to give practical insights into genuine business examples, this comprehensive book has a distinctly real-world focus throughout. Edited by a multi-national team, it draws together leading writers and researchers from across Europe, and is therefore a must-read for all those involved in advanced entrepreneurship with specific interests in high-tech start-ups.