Forming the 16th volume from this successful series, this book contains papers from the 16th International Conference on Railway Engineering Design and Operation. The included papers are a collection of works from researchers, academics and practitioners involved in railway engineering. There is a continuing need to update the use of advanced systems, promoting their general awareness throughout the management, design, manufacture and operation of railways and other emerging passenger, freight and transit systems. By emphasising the use of computer systems in advanced railway engineering, this book contributes to this goal. These research studies will be of interest to all those involved in the development of railways, including managers, consultants, railway engineers, designers of advanced train control systems and computer specialists.

Theory and Applications of Nonparenteral Nanomedicines presents thoroughly analysed data and results regarding the potential of nanomedicines conceived by diverse non-parenteral routes. In the context of nanotechnology-based approaches, various routes such as oral, pulmonary, transdermal, delivery and local administration of nanomedicine have been utilized for the delivery of nanomedicine. This book discusses the non-parenteral application of nanomedicine, its regulatory implications, application of mucus penetrating nanocarrier, and detailed chapters on development of nanomedicines developed for drug delivery by various route. Beginning with a brief introduction to the non-parenteral delivery of nanomedicine and the safety and regulatory implications of the nanoformulations, further chapters discuss the physiology of the biological barriers, the specificity of the nanocarriers as well as their multiple applications. Theory and Applications of Nonparenteral Nanomedicines helps clinical researchers, researchers working in pharmaceutical industries, graduate students, and anyone working in the development of non-parenteral nanomedicines to understand the recent progress in the design and development of nanoformulations compatible with non-parenteral applications.

The first edition of Health and Environmental Safety of Nanomaterials: Polymer Nanocomposites and Other Materials Containing Nanoparticles was published in 2014, but since that time, new developments in the field of nanomaterials safety have emerged, both at release and exposure, along with the expanding applications of the nanomaterials side. Numerous studies have been dedicated to the issue of biophysical interactions of nanoparticles with the human body at the organ, cellular, and molecular levels. In this second edition, all the chapters have been brought fully up to date. There are also four brand new chapters on the biophysical interaction of nanoparticles with the human body; advanced modeling approaches to help elucidate the nanorisks; safety measures at work with nanoparticles; and the health and environmental risks of graphene. It provides key knowledge and information needs for all those who are working in the research and development sector and need to learn more about the safety of nanomaterials.

On 14 April 1912, less than a week into a transatlantic trip from Southampton to New York, the largest luxury cruise liner in the world struck an iceberg off the coast of Labrador, causing the hull to buckle. The massive 50,000 ton ship hailed as 'unsinkable' was soon slipping into the cold Atlantic Ocean, the crew and passengers scrambling to launch lifeboats before being sucked into the deep. Of the 2,224 passengers and crew aboard, more than 1,500 died, making the sinking one of the deadliest for a single ship up to that time. The sinking has captured the public imagination ever since, in part because of the scale of the tragedy, but also because the ship represented in microcosm Edwardian society, with the super-rich sharing the vessel with poor migrants seeking a new life in North America. Other factors, such as why there were only enough lifeboats to hold half the passengers, also caused controversy and led to changes in maritime safety. In later years many survivors told their stories to the press, and Titanic celebrates these accounts. A final chapter examines the shipwreck today, which has been visited underwater by explorers, scientists and film-makers, and many artifacts recovered as the old liner steadily disintegrates. Titanic offers a compact, insightful photographic history of the sinking and its aftermath in 180 authentic photographs.

Research and Application of Hot In-Place Recycling Technology for Asphalt Pavement is the first comprehensive book on the topic that presents over two decades of theoretical and practical experience gained in China. The book gives comprehensive coverage of HIPR, including pavement evaluation, distress analysis, mix design, processes and equipment selection, implementation and acceptance criteria. In eight chapters, this book covers HIPR from theoretical and practical viewpoints, and provides detailed case-studies based on real-world experience. This book includes everything engineers need to apply HIPR to improve sustainability and reduce disruption during the maintenance and repair of asphalt.

In the nineteenth century, most American farms had a small orchard or at least a few fruit-bearing trees. People grew their own apple trees or purchased apples grown within a few hundred miles of their homes. Nowadays, in contrast, Americans buy mass-produced fruit in supermarkets, and roughly 70 percent of apples come from Washington State. So how did Washington become the leading producer of America's most popular fruit? In this enlightening book, Amanda L. Van Lanen offers a comprehensive response to this question by tracing the origins, evolution, and environmental consequences of the state's apple industry. Washington's success in producing apples was not a happy accident of nature, according to Van Lanen. Apples are not native to Washington, any more than potatoes are to Idaho or peaches to Georgia. In fact, Washington apple farmers were late to the game, lagging their eastern competitors. The author outlines the numerous challenges early Washington entrepreneurs faced in such areas as irrigation, transportation, and labor. Eventually, with crucial help from railroads, Washington farmers transformed themselves into "growers" by embracing new technologies and marketing strategies. By the 1920s, the state's growers managed not only to innovate the industry but to dominate it. Industrial agriculture has its fair share of problems involving the environment, consumers, and growers themselves. In the quest to create the perfect apple, early growers did not question the long-term environmental effects of chemical sprays. Since the late twentieth century, consumers have increasingly questioned the environmental safety of industrial apple production. Today, as this book reveals, the apple industry continues to evolve in response to shifting consumer demands and accelerating climate change. Yet, through it all, the Washington apple maintains its iconic status as Washington's most valuable agricultural crop.

In May 2017, Alan Pickering won the award for the `Greatest Single Contribution to Occupational Pensions (1998-2017)' at the Professional Pensions UK Pension Awards. It was a well-received tribute to the role he had played for more than twenty years. The Pickering Report, commissioned by the Blair government, had been a blunt, brutally honest and pragmatic assessment of what needed to be done if Britain's leadership position in occupational pensions was to be maintained. In this biography, Paddy Briggs, who worked closely with the subject, focuses on the world of pensions and Pickering's leading role in it. But the story is broader and more human than the highly technical world of retirement benefits. Pickering is a baby boomer who grew up in modest circumstances in the City of York. As a child, he was diagnosed with a degenerative eyesight disease, and by his twenties he was totally blind. His disability became more of a spur to ambition and accomplishment than a restraint. This included athletic achievements such as running marathons and being a serious participant in competitive race walking. He has reached the highest levels in the world of financial services and also became a well-known racehorse owner and a vice-president of the Racehorse Owners Association.

A New York Times Book Review Editors' Choice "Extremely wide-ranging and well researched . . . In a tradition of protest literature rooted more in William Blake than in Marx." -Adam Gopnik, The New Yorker The epic story of how coffee connected and divided the modern world Coffee is an indispensable part of daily life for billions of people around the world. But few coffee drinkers know this story. It centers on the volcanic highlands of El Salvador, where James Hill, born in the slums of Manchester, England, founded one of the world's great coffee dynasties at the turn of the twentieth century. Adapting the innovations of the Industrial Revolution to plantation agriculture, Hill helped turn El Salvador into perhaps the most intensive monoculture in modern history-a place of extraordinary productivity, inequality, and violence. In the process, both El Salvador and the United States earned the nickname "Coffeeland," but for starkly different reasons, and with consequences that reach into the present. Provoking a reconsideration of what it means to be connected to faraway people and places, Coffeeland tells the hidden and surprising story of one of the most valuable commodities in the history of global capitalism.

Population Dynamics of the Reef Crisis, Volume 87 in the Advances in Marine Biology series, updates on many topics that will appeal to postgraduates and researchers in marine biology, fisheries science, ecology, zoology and biological oceanography. Chapters in this new release cover SCTL disease and coral population dynamics in S-Florida, Spatial dynamics of juvenile corals in the Persian/Arabian Gulf, Surprising stability in sea urchin populations following shifts to algal dominance on heavily bleached reefs, Biophysical model of population connectivity in the Persian Gulf, Population dynamics of 20-year decline in clownfish anemones on coral reefs at Eilat, northern Red Sea, and much more.

Bio-Economy and Agri-Production: Concepts and Evidence bridges the knowledge gap between sustainability and bio-economy aspects of agri-production. It complements traditional perspectives of agri-production with advanced engineering, information and communication technologies recently applied in agri-business. Including knowledgebased agriculture and reflecting sustainability and circular economy principles, the book presents a holistic view of sustainable bio-economy, contributing to the development of integrated agricultural systems. As technology advances, agricultural production management practices are now being called upon to address the need for sustainability in the bio-economy. Bio-Economy and Agri-Production: Concepts and Evidence presents information to broaden the awareness and promotion of practices and technology to reduce the use of inputs, protect health and environment and improve resource-use efficiency. Topics that are addressed include circular economy in agri-business, lifecycle thinking, lean management, agri-chains, green production, and waste management. Bio-Economy and Agri-Production: Concepts and Evidence is a valuable reference for professionals, consultants, and policy making stakeholders in biosystems engineering and agricultural industries