This accessible and comprehensive textbook explores the role of advertising in the marketplace. It investigates how firms' advertising strategies are informative, persuasive or add value to the product advertised. The book explains in detail empirical methodologies used to identify the impact of advertising on consumer demand and on market structure, and reviews some recent empirical findings. It concludes with an in-depth exploration of digital advertising and auctions along with a framework for current antitrust investigations into two-sided platforms (Google, Facebook) that are funded by advertising revenues. How advertising works in the marketplace, and whether it works well, is a complex question to address because there are three sets of players involved-the firms that advertise their products, the potential consumers who view the ads and the platform or medium that intermediates between them. Understanding how these three sets of players interact is the key to understanding the role of advertising in a market economy. The book begins by looking at the rise of advertising in market economies, a phenomenon not accounted for in standard textbook microeconomic models and carefully explains why. This is followed by an examination, both theoretical and empirical, of how firms strategically use advertising to reach consumers and expand the demand for their products. There are also chapters focused on the challenges of deceptive advertising and regulation. The final chapters investigate how two-sided platforms, such as Google and Facebook, are sustained by advertising revenues, and include a review of auction theory and the structure of advertising auction exchanges. These chapters also provide a detailed analysis of public policy issues, including media bias and antitrust concerns. While designed for use by students in any course that covers the economics of advertising, this book is also an excellent resource for any reader interested in a deeper understanding of this important topic.

Elgar Research Agendas outline the future of research in a given area. Leading scholars are given the space to explore their subject in provocative ways, and map out the potential directions of travel. They are relevant but also visionary. Tourism is integral to local, regional and national development policies; as a major global economic sector, it has the potential to underpin economic growth and wider development. Yet, transformations in both the nature of tourism and the dynamic environment within which it occurs give rise to new questions with regards to its developmental role. This Research Agenda offers a state-of-the-art review of the research into the tourism-development nexus. Bringing together contributors from across the globe, this Research Agenda answers the key questions including: Are growth-focused tourism policies becoming increasingly detrimental to destination development? Can mass forms of tourism in fact generate more benefits than alternative forms of tourism? Does the role of the state in supporting tourism-induced development require reconsideration? How effective is tourism-related philanthropy in contributing to development? Is community-based tourism a realistic development policy? To what extent can tourism contribute to what is still the most pressing development challenge, namely poverty reduction? A Research Agenda for Tourism and Development offers valuable insights for students and researchers of development studies and tourism, as well as for policymakers and practitioners in tourism industries.

IN "THE ANTIDOTE," Barry Werth draws upon unprecedented inside reporting spanning more than two decades to provide a groundbreaking closeup of the upstart pharmaceutical company Vertex and the ferocious but indispensable world of Big Pharma that it inhabits.
In 1989, the charismatic Joshua Boger left Merck, then America's most admired business, to found a drug company that would challenge industry giants and transform health care. Werth described the company's tumultuous early days during the AIDS crisis in "The Billion-Dollar Molecule," a celebrated classic of science and business journalism. Now he returns to tell a riveting story of Vertex's bold endurance and eventual success.
The $325 billion-a-year pharmaceutical business is America's toughest and one of its most profitable. It's riskier and more rigorous at just about every stage than any other business, from the towering biological uncertainties inherent in its mission to treat disease; to the 30-to-1 failure rate in bringing out a successful medicine even after a molecule clears all the hurdles to get to human testing; to the multibillion-dollar cost of ramping up a successful product; to operating in the world's most regulated industry, matched only by nuclear power.
Werth captures the full scope of Vertex's twentyfive- year drive to deliver breakthrough medicines. At a time when America struggles to maintain its innovative edge, "The Antidote" is a powerful inside look at one of the most intriguing and important business stories of recent decades.

A New York Times Book Review Editors' Choice "Extremely wide-ranging and well researched . . . In a tradition of protest literature rooted more in William Blake than in Marx." -Adam Gopnik, The New Yorker The epic story of how coffee connected and divided the modern world Coffee is an indispensable part of daily life for billions of people around the world. But few coffee drinkers know this story. It centers on the volcanic highlands of El Salvador, where James Hill, born in the slums of Manchester, England, founded one of the world's great coffee dynasties at the turn of the twentieth century. Adapting the innovations of the Industrial Revolution to plantation agriculture, Hill helped turn El Salvador into perhaps the most intensive monoculture in modern history-a place of extraordinary productivity, inequality, and violence. In the process, both El Salvador and the United States earned the nickname "Coffeeland," but for starkly different reasons, and with consequences that reach into the present. Provoking a reconsideration of what it means to be connected to faraway people and places, Coffeeland tells the hidden and surprising story of one of the most valuable commodities in the history of global capitalism.

Blockchain has potential to revolutionize how manufacturers design, engineer, make and scale their products. Blockchain is gradually proving to be an effective "middleware" solution for enabling seamless interoperability within complex supply chains. Due to its technological nature, blockchain enables secure, transparent and fast data exchanges as well as allowing for the creation of immutable records databases The main advantage of Blockchain in Manufacturing Industries is product traceability, supply chain transparency, compliance monitoring, and auditability. Moreover, leveraging blockchain technology into a manufacturing enterprise can enhance its security and reduce the rates of systematic failures. So, blockchain is now used in various sectors of the manufacturing industry, such as automotive, aerospace, defense, pharmaceutical, consumer electronics, textile, food and beverages, and more. Hence, Blockchain should be seen as an investment in future-readiness and customer-centricity, not as an experimental technology - because, the evidence is overwhelming. This book will explore the strengths of Blockchain adaptation in Manufacturing Industries and Logistics Management, cover different use cases of Blockchain Technology for Manufacturing Industries and Logistics Management, and will discuss the role, impact and challenges of adopting Blockchain in Manufacturing industries and Logistics Management. The chapters will also provide the current open issues and future research trends of Blockchain, especially for Manufacturing Industries and Logistics, and will encapsulate quantitative and qualitative research for a wide spectrum of readers of the book.

People venture into tourist activities to expand their worldviews and experiences, and as such, it is common for them to face realities totally different from those they are used to. Therefore, it is essential to discuss tourist experiences related to issues with discrimination and equality such as racism, inherent prejudice, gender equality, indigenous rights, and experiences of the LGBTQIA+ community to ensure the tourism industry is inclusive and safe. Promoting Social and Cultural Equity in the Tourism Sector provides relevant theoretical frameworks and the latest findings from empirical research on diversity and equity applied to tourism activity. The book also contributes to the discussion about the nuances inherent to tourism activities and experiences at tourist destinations. Covering a wide range of topics such as gender bias, employability, and diversity education, this reference work is crucial for hotel managers, activists, travel agencies, tour organizations, industry professionals, government officials, policymakers, researchers, scholars, practitioners, academicians, instructors, and students.

This incisive volume of the Elgar Encyclopedia of Environmental Law offers a broad analysis of the foundations, main concepts, and substantive and procedural requirements of selected chemical law regimes as they pertain to the environment. Featuring contributions from more than 40 expert scholars and practitioners in the field, the volume focuses on chemical regulatory systems from representative jurisdictions, including the EU and the US, to provide a coherent overview of this expansive and often fragmented area of law. Divided into five thematic parts, the volume first examines the fundamental concepts of chemical law, addressing topics including risk assessment, nomenclature, environmental justice and animal testing. Entries then discuss types of chemicals and exposures, regulation of chemicals in products and manufacturing, and waste and contamination, as well as covering liability rules as they apply to chemicals. This volume will be an essential resource for scholars and students looking for a clear understanding of chemicals regulation and governance from environmental and public health perspectives at both national and international levels. Its insights into policy developments and liability issues will also be of interest to policymakers and practitioners.

Coronavirus Drug Discovery, Volume Three: Druggable Targets and In Silico Update presents comprehensive information on drug discovery against COVID-19. Chapters in Part One of this volume describe the various druggable targets and associated signaling pathways for effective targeting of SARS-CoV-2. In Part Two, chapters discuss the various computational approaches and in silico studies against SARS-CoV-2. Written by global team of experts, this book is an excellent resource that will be extremely useful to drug developers, medicinal chemists, pharmaceutical companies in R&D, research institutes in both academia and industry, and the National Library of Medicines and Health. In addition, agencies such as the National Institutes of Health, Centers for Disease Control and Prevention, World Health Organization, European Medicines Agency, the US Food and Drug Administration, and all others involved in drug discovery against COVID-19 will find this book useful.

Resonance Self-Shielding Calculation Methods in Nuclear Reactors presents the latest progress in resonance self-shielding methods for both deterministic and Mote Carlo methods, including key advances over the last decade such as high-fidelity resonance treatment, resonance interference effect and multi-group equivalence. As the demand for high-fidelity resonance self-shielding treatment is increasing due to the rapid development of advanced nuclear reactor concepts and progression in high performance computational technologies, this practical book guides students and professionals in nuclear engineering and technology through various methods with proven high precision and efficiency.

Bio-Based Flame Retardants for Polymeric Materials provides a comprehensive overview of flame retardants derived directly and indirectly from plant sources, drawing on cutting-edge research and covering preparation methods, testing and evaluation techniques, enhanced properties, and end applications. Chapters introduce bio-based materials in the context of additives for flame retardancy, explaining fundamentals and testing methods and analyzing synthetic approaches and the potential advantages of pursuing a bio-based approach. This is followed by detailed coverage of bio-based retardants, with each chapter covering a specific source and guiding the reader systematically through preparation techniques, evaluation methods, properties and applications. Throughout the book, the latest progress in the field is critically reviewed, and there is a continual emphasis on novel approaches to achieve enhanced properties and performant materials. This is an essential guide for all those with an interest in innovative, sustainable flame retardant additives for polymeric materials, including researchers, scientists, advanced students, and more.

Supply of oil and gas continues to increase as well as natural events such as hurricanes, while engineers and safety managers are not well trained on storage tank engineering and leak detection, one of the most vulnerable and least studied components of oil and gas storage equipment. Above Ground Storage Tank Oil and Chemical Spills gives engineers and researchers a training guide on tank design, tank failure modes and risk analysis. Bridging between research and application, this reference sends an integrated engineering approach backed by both corporate and academic contributors focused specifically on storage tanks, their spills, case histories, and technical aspects of leakage from storage tanks. Additional topics include regulations, differences between spills from storage tanks and other sources, and supported by extensive data and additional references. Above Ground Storage Tank Oil and Chemical Spills delivers a much-needed knowledge source for today's engineers and managers to keep supply and personnel safe.

Two-time Peabody Award-winning writer and producer Ira Rosen reveals the intimate, untold stories of his decades at America's most iconic news show. It's a 60 Minutesstory on 60 Minutes itself. When producer Ira Rosen walked into the 60 Minutes offices in June 1980, he knew he was about to enter television history. His career catapulted him to the heights of TV journalism, breaking some of the most important stories in TV news. But behind the scenes was a war room of clashing producers, anchors, and the most formidable 60 Minutes figure: legendary correspondent Mike Wallace. Based on decades of access and experience, Ira Rosen takes readers behind closed doors to offer an incisive look at the show that invented TV investigative journalism. With surprising humor, charm, and an eye for colorful detail, Rosen delivers an authoritative account of the unforgettable personalities that battled for prestige, credit, and the desire to scoop everyone else in the game. As one of Mike Wallace's top producers, Rosen reveals the interview secrets that made Wallace's work legendary, and the flaring temper that made him infamous. Later, as senior producer of ABC News Primetime Live and 20/20, Rosen exposes the competitive environment among famous colleagues like Diane Sawyer and Barbara Walters, and the power plays between correspondents Chris Wallace, Anderson Cooper, and Chris Cuomo. A master class in how TV news is made, Rosen shows readers how 60 Minutes puts together a story when sources are explosive, unreliable, and even dangerous. From unearthing shocking revelations from inside the Trump White House, to an outrageous proposition from Ghislaine Maxwell, to interviewing gangsters Joe Bonanno and John Gotti, Jr., Ira Rosen was behind the scenes of some of 60 Minutes' most sensational stories. Highly entertaining, dishy, and unforgettable, Ticking Clock is a never-before-told account of the most successful news show in American history.

This book examines the role of artists in Egypt during the 2011 revolution, when street art from graffiti to political murals became ubiquitous facets of revolutionary spaces. Through interviews, personal testimonies, and accounts of the lived experience of 25 street artists, the book explores the meaning of art in revolutionary political contexts, specifically by focusing on artistic production during 'liminal' moments as the events of the Egyptian revolution unfolded. The author privileges the perspective of the actors themselves to examine the ways that artists reacted to events and conceived of their art as means to further the goals of the revolution. Based on fieldwork conducted in the years since 2011, the book provides a narrative of Egyptian artists' participation in and representations of the revolution, from hopeful beginnings to the subsequent crackdown and election of al-Sisi.

In a globalized world full of noise, brands are constantly launching messages through different channels. For the last two decades, brands, marketers, and creatives have faced the difficult task of reaching those individuals who do not want to watch or listen to what they are trying to tell them. By producing fewer ads or making them louder or more striking, more brands and communications professionals are not going to get those people to pay more attention to their messages; they will only want to avoid advertising in all media. Examining the Future of Advertising and Brands in the New Entertainment Landscape provides a theoretical, reflective, and empirical perspective on branded content and branded entertainment in relation to audience engagement. It reviews different cases about branded content to address the dramatic change that brands and conventional advertising are facing short term. Covering topics such as branded content measurement tools, digital entertainment culture, and government storytelling, this premier reference source is an excellent resource for marketers, advertising agencies, brand managers, business leaders and managers, communications professionals, government officials, non-profit organizations, students and educators of higher education, academic libraries, researchers, and academicians.

Fast Reactors: A Solution to Fight Against Global Warming presents the current status of fast-reactor nuclear generation technology, with a focus on ecology and sustainability benefits for the future. Author Joel Guidez analyzes past failures and limited deployment reasons to help drive this power generation method forward to a cleaner and more sustainable energy environment. The book covers safety aspects, short-life waste management, multirecycling, and biodiversity preservation to provide a well-rounded reference on the topic.

Elgar Research Agendas outline the future of research in a given area. Leading scholars are given the space to explore their subject in provocative ways, and map out the potential directions of travel. They are relevant but also visionary. Offering a unique collection of established and emerging perspectives on event management, this Research Agenda investigates contemporary themes and innovative methodologies. 10 chapters cover core topics in the current academic debate, exploring the development of event management from a management-oriented field into a multidisciplinary research area. Organised into three parts, the Research Agenda contains international contributions from academics across tourism, geography, management, psychology and sociology fields. Initially tackling events in society, the book moves on to look specifically at the consumer, and finally examines the event organization. Chapters recommend the integration of events in geographical and political contexts, suggesting research agendas for the future that focus on the spectator, the participant and, ultimately, the consumer. Critical reading for management and tourism scholars, this book offers key insights to developing topics in the field. Event practitioners and policy makers will also greatly benefit from reading this.

To enter the sports, events, and hospitality industry, it is necessary to develop and hone certain skills to ensure competitiveness. These skills must be studied further to educate those interested in pursuing a career in these fields on what it takes to begin this long process and enhance their employability. Employability and Skills Development in the Sports, Events, and Hospitality Industry provides insight into current professionals working in the sports, events, tourism, and hospitality industry and considers the skills and qualifications necessary to work within or enter the industries. Covering key topics such as hard skills, volunteerism, virtual events, and educational institutions, this reference work is ideal for event managers, coaches, property owners, entrepreneurs, industry professionals, researchers, academicians, scholars, educators, and students.

Providing an overview of industrial development using a variety of different approaches and perspectives, the Handbook of Industrial Development brings together expert contributors and highlights the current multiple and interdependent challenges that can only be addressed using an interdisciplinary approach. Chapters discuss the existing issues faced by industry following both the digital and environmental transitions, highlighting their regional roots and the interplay with the wider institutional framework. Investigating the necessity for companies to design new products and production processes and also re-think their corporate responsibilities, this Handbook illustrates the need for a much broader vision taking into account historical, social, political and cultural viewpoints at all governmental levels. Furthermore, it takes an analytical look at further research, including insightful directions for future industrial development policies. Answering complex policy questions for today, this crucial Handbook will be invaluable for policymakers looking for insights into sustainable industrial development as well as practitioners who are seeking an up-to-date comprehensive overview of the topic. Economic development and innovation scholars and researchers will also find the future research ideas interesting and informative.

Providing a comprehensive overview and analysis of the latest research in the growing field of public transport studies, this Handbook looks at the impact of urbanisation and the growth of mega-cities on public transport. Chapters examine the significant challenges facing the field that require new and original solutions, including congestion and environmental relief, and the social equity objectives that justify public transport in cities. This cross-disciplinary Handbook explores current topics in public transport research, focusing on the impact of innovative research on planning and operations in practice. Looking at the research frontiers in this increasingly complex and growing industry, the Handbook offers detailed analysis of the foundations, trends and futures of research, user perspectives, policy, planning and operational perspectives, and the future of service developments. A critical read for transport and urban planning students and scholars, this cutting-edge book showcases important case studies and insights into current research. The practical applications of research discussed in the Handbook will also be useful to transport and urban planners as well as public transport regulators.

This book explores the interplay between regulation and emerging technologies in the context of synthetic biology, a developing field that promises great benefits, and has already yielded fuels and medicines made with designer micro-organisms. For all its promise, however, it also poses various risks. Investigating the distinctiveness of synthetic biology and the regulatory issues that arise, Alison McLennan questions whether synthetic biology can be regulated within existing structures or whether new mechanisms are needed. Adopting an interdisciplinary approach, McLennan draws on diverse areas of law, the science of synthetic biology and the history and sociology of science. She concludes that synthetic biology presents novel regulatory challenges relating to environmental risk, biosafety, biosecurity and intellectual property. These challenges arise from the uniqueness of the science, the nature of its communities of scientists (including citizen scientists or 'biobunks') and the uncertainty surrounding possible hazards. Some scientists see intellectual property protection as a way to push innovation forward (bioentrepreneurs), while others openly share synthetic biology tools such as BioBricks. By understanding the range of regulatory challenges, the book make a case for enhanced regulation that protects us from synthetic biology's risks, whilst capturing its potential to improve our world. Regulation of Synthetic Biology will be essential reading for academics and students in the social sciences and law, as well as for scientists working in synthetic biology, and policymakers in innovation, science and the regulation of these fields.

W.A.J. Coetzee was born in Piketberg in 1928. After matriculating, he started work as a post-office clerk. He was later transferred to the office of the Deputy Postmaster-General in Pretoria. As an extramural student he successively obtained his B.A., B.A. Honours, and M.A. degrees in Public Administration from the University of Pretoria. In 1973 he was appointed senior lecturer and head of the Department of Public Administration at the University of Durban-Westville. He became a professor in 1977 after obtaining his doctorate (D.Phil.) in 1976 from the University of Pretoria and has subsequently served as dean of the Faculty of Commerce. Professor Coetzee is the author of a number of books and articles in Public Administration in South Africa and has delivered papers at conferences locally and abroad. He has been a member, director or chairman of various cultural and professional organizations, and has also served on a number of university senate committees.