Reliability and Probabilistic Safety Assessment in Multi-Unit Nuclear Power Plants presents the risk contributions from single and multi-unit Nuclear Power Plants to help aggregate the risks that may arise due to applicable hazards and operating states. The book combines the key features of multi-unit risk assessment in one resource, reviewing the practices adopted in various countries around the globe to exemplify the dependencies between units on a site. These dependencies include multi-unit interactions, environmental stresses, the sharing of systems, and the sharing of human resource in a control room, factors which can all introduce an increase potential for heightened accident conditions. This book helps readers systematically identify events and evaluate techniques of possible accident outcomes within multi-units. It serves as a ready reference for PSA analysts in identifying a suitable site and the sharing of resources, while carrying out multi-unit risk assessments to ensure the safety of the public and the environment. It will also be valuable for nuclear researchers, designers and regulators of nuclear power plants, nuclear regulatory agencies, PSA engineers and practicing safety professionals.

Power-to-Gas: Bridging the Electricity and Gas Networks introduces the concept of Power-to-Gas (P2G) technologies in the Whole Energy System framework and related Vector-Coupling Technologies (VCTs). The boo provides a comprehensive approach to the economic, technical and environmental evaluation of P2G technology to make more effective use of the surplus power of renewable units. It covers converting electricity to hydrogen or methane, and the challenges, analytical solutions and future trends of P2G applications. Moreover, the reference features technology overviews and literature reviews in each chapter, along with concepts, appropriate definitions, fundamentals and contexts in the energy systems. Finally, modeling issues and requirements for analysis Gas and Power Vector-Coupling Technologies are presented and supported by real-world case studies and experimental examples. By uniquely analyzing issues from the whole energy system perspective, this book plays a pivotal role in supporting researchers and academicians in electrical, mechanical and energy engineering in their long-term decarbonization strategies.

Medicinal Chemistry of Anticancer Drugs, Third Edition provides an updated resource for students and researchers from the point-of-view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. The new edition includes updated sections on the hot topic of cancer immunotherapy, cancer polypharmacology, multitargeted cancer therapy, medicinal chemistry of cancer diagnosis, theragnostic anticancer agents, and pre-mRNA processing in cancer. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a unique and valuable perspective from the point-of-view of medicinal chemistry and drug design. It will be useful to undergraduate and postgraduate students of medicinal chemistry, pharmacology, biological chemistry, pharmacy and other health sciences. Researchers and practitioners will find a comprehensive treatment of the topic and a large number of references, reviews and primary literature.

There is a dire need for a comprehensive pedagogical resource both on diverse approaches to teaching sports economics and the use of sports to teach broader principles of economic concepts. This book does exactly that. The contributions from leading scholars and teachers in both fields will help all instructors looking to raise their teaching game. The pedagogy in this book covers a wide array of active and engaged teaching techniques to demonstrate interesting ways to engage students and to get them excited about sports economics and economic concepts in general. Chapters cover topics such as legal case studies that impact North American leagues, discrimination and gender bias in sports economics and best practices for supervising undergraduate student research. The innovative approaches and methods presented are applicable to both small and large class sizes. Practical advice for designing field trip-, guest speaker-, and case-study-based classes, and techniques for using data-driven exercises, film and straightforward classroom experiments are included. This book will appeal to two primary audiences: undergraduate economics instructors and sports economics/management instructors. The teaching methods may be easily adapted to most economic classes, and the breadth of material provides instructors with assistance in creating course syllabi, outlining teaching plans, generating student interest, and increasing the efficacy of their pedagogy.

This Handbook brings together experts from around the world to reflect critically on the relationship between tourism and rural community development. It first orients the reader in the important conceptual and epistemological foundations of the topic, before moving to consider key concepts and the most significant and salient theoretical and methodological developments in the field. Chapters written by a range of well-established, leading and emerging scholars in the field consider crucial issues facing tourism development in rural communities across different geographical settings. The Handbook represents a variety of traditional and emerging forms of scholarly writing, including theoretically driven chapters, empirical case studies and first-person narratives, to offer a detailed study of the topic. With a forward-looking angle, it studies tourism development in rural areas, including working with rural communities, tourism governance and ethical considerations. Chapters also consider new directions in the field, examining food and tourism, degrowth, landscapes, animals, social impacts and women social entrepreneurs. This comprehensive and innovative Handbook offers a wealth of empirical and theoretical knowledge on tourism and rural community development, and as such will be a critical resource for tourism, development studies and human geography scholars and students.

This incisive volume of the Elgar Encyclopedia of Environmental Law offers a broad analysis of the foundations, main concepts, and substantive and procedural requirements of selected chemical law regimes as they pertain to the environment. Featuring contributions from more than 40 expert scholars and practitioners in the field, the volume focuses on chemical regulatory systems from representative jurisdictions, including the EU and the US, to provide a coherent overview of this expansive and often fragmented area of law. Divided into five thematic parts, the volume first examines the fundamental concepts of chemical law, addressing topics including risk assessment, nomenclature, environmental justice and animal testing. Entries then discuss types of chemicals and exposures, regulation of chemicals in products and manufacturing, and waste and contamination, as well as covering liability rules as they apply to chemicals. This volume will be an essential resource for scholars and students looking for a clear understanding of chemicals regulation and governance from environmental and public health perspectives at both national and international levels. Its insights into policy developments and liability issues will also be of interest to policymakers and practitioners.

This Handbook offers an insightful journey through the landscape of research methods used to study the phenomenon of creativity, addressing the maturation of creativity research and its methodological approaches. Offering a methodological panorama for the global community of creativity researchers, contributors provide markers and viewpoints to better orient scholars and encourage reflection on how one might produce exceptional research on the burgeoning field of creativity. Chapters provide insights into a variety of methodological approaches, contemplating their benefits, limitations, scope of validity and ethical implications. As a contrast, sharp and to the point vignettes, similar to parables, are included to make the reader think. Allowing space for both established methods and new approaches, this Handbook is crucial reading for researchers interested in creativity at all levels looking to adopt innovative methodological approaches and broaden their research horizons. Contributors include: S. Acar, J. Baer, D.M. Boje, I. Bouty, H. Cairns-Lee, G. Cattani, R. Chia, L. Chiapello, A. Cropley, D. Cropley, J. Dul, S. Ferriani, G. Formilan, V. Glaveanu, M.-L. Gomez, M. Hanchett Hanson, P. Hibbert, R. Kark, J.C. Kaufman, A.K. Kofinas, C. Mainemelis, R. Reiter-Palmon, R. Robinson, N. Rosenkranz, M. Runco, M. Sinclair, P. Sowden, U. Ogurlu, M. Tempelaar, K. Unsworth

Now with a new afterword covering the months-long landmark trials of Elizabeth Holmes and Sunny Balwani. ‘I couldn’t put down this thriller . . . the perfect book to read by the fire this winter.’ Bill Gates Winner of the Financial Times/McKinsey Business Book of the Year Award 2018 The riveting true story of the breathtaking rise and shocking collapse of Theranos, the multibillion-dollar biotech startup founded by Elizabeth Holmes, by the prize-winning journalist who first broke the story and pursued it to the end, despite pressure from its charismatic CEO and threats by her lawyers. In 2014, Theranos founder and CEO Elizabeth Holmes was widely seen as the female Steve Jobs: a brilliant Stanford dropout whose startup ‘unicorn’ promised to revolutionize the medical industry with a machine that would make blood testing significantly faster and easier. Backed by investors such as Larry Ellison and Tim Draper, Theranos sold shares in a fundraising round that valued the company at more than $9 billion, putting Holmes’s worth at an estimated $4.7 billion. There was just one problem: the technology didn’t work. In Bad Blood, John Carreyrou tells the riveting story of the biggest corporate fraud since Enron, a tale of ambition and hubris set amid the bold promises of Silicon Valley. ‘Chilling . . . Reads like a West Coast version of All the President’s Men.’ New York Times Book Review

Interest in tourism with a social imperative is gaining momentum not only amongst policy makers, but also researchers and the academy. This thought-provoking and timely Handbook considers the impact and challenges that social tourism has on people's lives. Integrating case studies from around the world, chapters showcase the latest research on social tourism and its potential role in tackling the challenges posed by modern, mass tourism development that can lead to sustainable alternatives and social equity in participation. Contributors explore tourism activities that are directed towards positive social and personal outcomes for people who would not be able to access leisure or holiday travel without such interventions and illustrate the social imperative of tourism as a force for good. The Handbook of Social Tourism enables academics and students from various disciplines, as well as practitioners in the tourism sector, to obtain a more holistic understanding of this phenomenon and offers an enlightening and stimulating read. Contributors include: C. Billen, N. Carr, J.D. Cisneros-Martinez, V. Cops, A. Diekmann, V. Eichhorn, A.E. Estrada-Gonzalez, C. Eusebio, A. Fernandez-Morales, J. Finniear, E. Herengodts, E. Hermans, P. Hunter Jones, L. Jolin, K.I. Kakoudakis, M. Kay Smith, R. Komppula, T. Kosar, J. Lima, S. McCabe, L. Minnaert, N. Morgan, B. Prideaux, S. Pyke, J. Pyke, G. Qiao, Y. Ram, A.C. Reyes Uribe, H. Schanzel, E. Schenkel, G. Shaw, L. Sie, E. Vento, M. Vilele de Almeida, M. Vincent, J. Wooton

Edward Snowden, the man who risked everything to expose the US government’s system of mass surveillance, reveals for the first time the story of his life, including how he helped to build that system and what motivated him to try to bring it down.

In 2013, twenty-nine-year-old Edward Snowden shocked the world when he broke with the American intelligence establishment and revealed that the United States government was secretly pursuing the means to collect every single phone call, text message, and email. The result would be an unprecedented system of mass surveillance with the ability to pry into the private lives of every person on earth. Six years later, Snowden reveals for the very first time how he helped to build this system and why he was moved to expose it.

Spanning the bucolic Beltway suburbs of his childhood and the clandestine CIA and NSA postings of his adulthood, Permanent Record is the extraordinary account of a bright young man who grew up online – a man who became a spy, a whistleblower, and, in exile, the Internet’s conscience. Written with wit, grace, passion, and an unflinching candor, Permanent Record is a crucial memoir of our digital age and destined to be a classic.

Each unit is presented in topic spreads and designed with a variety of learning styles and abilities in mind, making the content even more accessible. Covers 14 units - enough for completion of a full Level 1 Diploma. Contains a variety of engaging, active and practical activities to cater for the differing needs of all your learners. Functional Skills signposting shows naturally ocurring opportunities for practising Functional Skills.

This volume of the Elgar Encyclopedia of Environmental Law provides thorough and detailed coverage of the changing meanings and roles of water law, from the local to the global. It examines the rules of ownership, rights of use, and dispute resolution that address access, allocation, and protection of water resources. Written by leading scholars and practitioners from across the globe, the volume is organised into thematic parts, beginning with an overview of fundamental concepts in water law, as well as pervasive issues such as the interplay of water law, governance and politics, and the water-energy nexus. Entries then discuss topics in international, regional, and national water law, before exploring broader questions about the intersections between water law and areas such as development, infrastructure, and indigenous rights. The volume also offers insights into potential future directions of water law and governance in response to the increasingly pressing ecological issues. This authoritative volume will be a vital resource for all scholars and students of environmental law. Practitioners, policy makers and water managers will also find its accessible discussion of complex topics in water law particularly beneficial.

Bringing together over fifty leading global experts, this Research Handbook provides a state-of-the-art overview of research findings regarding Human Resource Management (HRM) in the public sector. Original chapters provide useful insights from two different disciplines: public administration and HRM. They illustrate that the public context of organisations matters and discuss research findings detailing how this plays out in practice. Divided into six distinct parts, this Research Handbook covers the key areas of strategic HRM, the HRM cycle, HRM and the outcomes, linking mechanisms in the HRM value chain, as well as HRM and context. Providing crucial information, Part VI examines the main future challenges for HRM in public organisations and provides extensive knowledge across different areas for future research. This engaging Research Handbook will be an excellent resource for scholars in public administration as well as HRM practitioners and scholars with interests in the public contexts and how this affects HRM. It will also provide obligatory reading for advanced students to understand the distinctiveness of HRM in public organisations.

Providing an overview of industrial development using a variety of different approaches and perspectives, the Handbook of Industrial Development brings together expert contributors and highlights the current multiple and interdependent challenges that can only be addressed using an interdisciplinary approach. Chapters discuss the existing issues faced by industry following both the digital and environmental transitions, highlighting their regional roots and the interplay with the wider institutional framework. Investigating the necessity for companies to design new products and production processes and also re-think their corporate responsibilities, this Handbook illustrates the need for a much broader vision taking into account historical, social, political and cultural viewpoints at all governmental levels. Furthermore, it takes an analytical look at further research, including insightful directions for future industrial development policies. Answering complex policy questions for today, this crucial Handbook will be invaluable for policymakers looking for insights into sustainable industrial development as well as practitioners who are seeking an up-to-date comprehensive overview of the topic. Economic development and innovation scholars and researchers will also find the future research ideas interesting and informative.

"These case stories focus on an important event, mishap, management practice, or ethical question, and present important lessons to the reader. Their objective is to educate, inspire, motivate, challenge, and encourage food professionals to better understand food safety management and to help increase job effectiveness and productivity with ethics and integrity. Each case addresses its subject in terms of relevance and application to food safety and covers all types of risks (e.g., microbial, chemical, physical) associated with each step of the food chain. In an engaging format, the book provides an analysis of incidents or near misses. It highlights pitfalls in food safety management and provides key insight into the means of avoiding them. The book captures the real-life experience of food safety professionals around the world in very challenging situations, and invites the reader to reflect on and discuss the situations depicted. It is an essential reference for students and food professionals, including scientists, managers, trainers, food inspectors, public health officials, and more. Each of the 87 short cases includes a paragraph on "Discussion and key learnings", which will appeal equally to educators, students and working professionals in this field."

Developing Sustainable and Health Promoting Cereals and Pseudocereals: Conventional and Molecular Breeding reviews the most recent developments in the fields of cereal and pseudocereal breeding, with particular emphasis on the latest biotechnological techniques likely to lead to breakthrough changes in plant breeding. The book provides comprehensive information on the use of genetic resources or pre-breeding activities to improve health-related properties of cereals and pseudocereals. The text also explores targeted field-management practices and the latest in biotechnological methodologies, and offers a cohesive overview necessary for understanding the potential impacts and benefits of improved production of cereals and pseudocereals with high-nutritional value.

Water, Land, and Forest Susceptibility and Sustainability, Volume 2: Insight Towards Management, Conservation and Ecosystem Services brings an interdisciplinary perspective to solving complex problems in sustainability, utilizing the latest research and technologies, and includes case studies that emphasize the applications of remote sensing, GIS, and image processing for addressing the current state and future needs to achieve sustainability. As forests, land, and water are among the most precious resources on earth, emphasizing the need to conserve them for future generations and, of course, a safe and sustainable planet. The assessment of the susceptibility of all these three precious resources must therefore be addressed to inform their sustainable management. This second volume focuses on environmental management, conservation, and ecosystem services and provides information on forest, land, and water resources, presenting in integrated manner various aspects of their characterization, susceptibility, and sustainability.

Elgar Research Agendas outline the future of research in a given area. Leading scholars are given the space to explore their subject in provocative ways, and map out the potential directions of travel. They are relevant but also visionary. Presenting cutting-edge thoughts on media economics, its history and development, and looking forward to its future, this timely book investigates the changing face of the field. With contributions from some of the most prominent media economics scholars in the world, this provocative and visionary Research Agenda covers theory development, consumer and audience demand, information and cultural goods, and technological dimensions. Chapters explore globalization, industry organization, social and ethical aspects of media firms, new media viability and the historical eras of media economics. Presenting a range of streams of inquiry and topics needing more study and development, this Research Agenda looks at new and innovative ways to stimulate thought around key research questions and designs. PhD students and scholars of media studies and media economics will benefit from the expansion of basic concepts, theories and methods found in this key book. It will also be critical reading for media professionals looking to understand more about the impact and importance of contemporary media relations. Contributors include: A.B. Albarran, �. Arrese, M. Barrett, A.J. Coffey, C.A. Hollifield, W.-y. Hsu, C. Kolo, Y.-l. Liu, M. Medina, B.I. Mierzejewska, M.E. Gutiérrez-Rentería, U. Rohn, A. Sánchez-Tabernero, C. Shao, X. Zhang

Global. International. Multinational. These are the words that describe and move business today. Sport is no exception. This text describes the international governance structures that shape sport throughout the world and explains the organisation and development internationally of both professional and amateur sport. International trends in sport and the organisation of international sporting events are among the topics addressed.

Millions of patients travel abroad every year, and the number of trips around the world to benefit from health services is increasing. The high level of global demand for health services has influenced the rapid development of the tourism industry. Many destinations providing high-quality healthcare services at low prices have emerged. Due to these developments in the industry, the health tourism market, one of the fastest growing markets, has emerged. Countries operating in the industry are also striving to increase their market shares. Therefore, it is important to understand the dynamics of this global phenomenon. Global Perspectives on the Opportunities and Future Directions of Health Tourism provides new theoretical, practical, and strategic insights into the field of health tourism. It discusses in detail the health tourism industry and its importance for the global economy, countries, and destinations. Covering topics such as elderly consumers, historical development, and image and branding, this premier reference source is an essential resource for government officials, hospital administrators, policymakers, business managers and executives, students and educators of higher education, librarians, researchers, and academicians.

Contextualisation: The nature and role of public policy. Theories and models for analysing public policy. History and development of policy studies and policy analysis. Public policy in more and lesser developed states. The public policy process: Policy agenda setting. Policy design. Policy decision making. Policy implementation. Programme management, project management and public policy implementation. Policy evaluation. Policy dynamics - change, failure and success. Capacity building for policy improvement: Education and training for policy analysis. The prevalence and institutionalisation of policy analysis in government.

The inspiration behind the Netflix tv series Painkillers, starring Uzo Aduba and Matthew Broderick THE SUNDAY TIMES BESTSELLER Now on BBC Radio 4 'Book of the Week' Winner of the 2021 Baillie Gifford Prize for Non-Fiction Shortlisted for the 2021 Financial Times/McKinsey Business Book of the Year Award One of Barack Obama's Favorite Books of 2021 Shortlisted for the Crime Writers' Association Gold Dagger for Non-Fiction The gripping and shocking story of three generations of the Sackler family and their roles in the stories of Valium, OxyContin and the opioid crisis. 'One of those authors I will always read, no matter what the subject matter, which is why I gobbled up Empire of Pain . . . a masterclass in compelling narrative nonfiction.' - Elizabeth Day, The Guardian '30 Best Summer Reads' 'You feel almost guilty for enjoying it so much' - The Times The Sackler name adorns the walls of many storied institutions - Harvard; the Metropolitan Museum of Art; Oxford; the Louvre. They are one of the richest families in the world, known for their lavish donations in the arts and the sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing Oxycontin, a blockbuster painkiller that was a catalyst for the opioid crisis - an international epidemic of drug addiction which has killed nearly half a million people. In this masterpiece of narrative reporting and writing, award-winning journalist and host of the Wind of Change podcast Patrick Radden Keefe exhaustively documents the jaw-dropping and ferociously compelling reality. Empire of Pain is the story of a dynasty: a parable of twenty-first-century greed.

Databook of Surface Modification Additives, Second Edition contains data on ten groups of additives, including anti-scratch and mar-preventing additives, additives for surface tension reduction and wetting, hydrophobization additives, gloss enhancement and surface matting additives, additives for the formation of tack-free surface and tackifiers, and stain inhibiting additives. The information on each is divided into five sections, including General Information, Physical-Chemical Properties, Health and Safety, Ecological Properties, and Use and Performance. This data is provided for approximately 360 of the most important surface modification additives produced and used today. This databook will be an extremely useful resource for engineers, researchers and technicians interested in using additives to modify and improve the surface properties of materials.

This engaging and timely book provides an in-depth analysis of work and labour relations within global platform capitalism with a specific focus on digital platforms that organise labour processes, known as labour platforms. Well-respected contributors thoroughly examine both online and offline platforms, their distinct differences and the important roles they play for both large transnational companies and those with a smaller global reach. Chapters explore how labour platforms have become controversial and ambiguous as they increasingly appear to provide important sources of work and income globally but conversely raise concerns over exploitation of workers and the lack of legal protection provided to them. Offering a global perspective and including studies from different continents, the book covers three key areas: platform work in the wider context of contemporary capitalism, labour platforms from an international division of labour perspective, and labour processes and relations. This informative and thought-provoking book is an excellent resource for scholars with a particular interest in political economy, the sociology of work, labour relations and labour policies. Policymakers and regulators looking to understand how to effectively apply existing regulations for platform workers when creating new business models will also find this an invigorating read.