This volume of Progress in Molecular Biology and Translational Science focuses on the molecular basis of drug addiction.

The skin is the largest human organ system. Loss of skin integrity due to injury or illness results in a substantial physiologic imbalance and ultimately in severe disability or death. From burn victims to surgical scars and plastic surgery, the therapies resulting from skin tissue engineering and regenerative medicine are important to a broad spectrum of patients. Skin Tissue Engineering and Regenerative Medicine provides a translational link for biomedical researchers across fields to understand the inter-disciplinary approaches which expanded available therapies for patients and additional research collaboration. This work expands on the primary literature on the state of the art of cell therapies and biomaterials to review the most widely used surgical therapies for the specific clinical scenarios.

Fundamentals of Nursing, unlike other texts, is not limited to just one specialism, but considers nursing across all fields from Adult, to Child, Mental Health and Learning Disabilities as well as both within the acute and community settings. Fundamentals of Nursing will help you to prepare and succeed in the varied and exciting career you have chosen, enabling you to become the skilled, flexible and confident nurse modern healthcare demands. Fundamentals of Nursing helps you on this journey with comprehensive coverage of contemporary professional nursing developed to compliment the latest Standards of Proficiency for Pre-Registration Nursing Education (Nursing & Midwifery Council 2010) and the Essential Skills Clusters. Support for your learning is provided through: Full Colour Presentation - view procedures and other visuals in realistic full colour. Diagrams and text features stand out in the colourful and highly developed text design. Black and white and dullness are banned. Don't accept anything less! Step-by-Step Clinical Procedures, often including images, are based on clinical evidence and guide you through the procedure. You will also find Skills revision videos (available within MyNursingKit) which link to these procedures. Case Studies - helping to put nursing into context, these realistic scenarios across a range of nursing fields and settings are included in all chapters. Relevant guidance is included to help you understand what you need to consider when confronted with a similar situation. These are suitable for both personal reflection and group discussion. Newly Developed Chapters devised by specialists on Mental Health, Child and Learning Disability Nursing have been added to promote the widest possible experience and understanding regardless of your field, promoting the basic skills to meet any patient's needs independent of age or vulnerability. Clinical Alerts highlight particular areas of practice that you need to take into account when caring for an individual or group. Activities help you reinforce and prove your learning. Reference answers are provided to check your understanding. Lifespan Considerations highlight alternative practices when caring for infants, children and/or older adults. Community Considerations provide information on caring for individuals in the home care and community setting. This prepares you for more than just the acute setting. MyNursingKit - a premium website integrated with the text providing you with extra practice, revision and support. Including diagnostic tests, interactive scenario simulations and skills videos among other resources. Go to www.pearsoned.co.uk/kozier to login!

Active and Assisted Living (AAL) systems aim at improving the quality of life and supporting independent and healthy living of older or impaired people by using a distributed network of sensors and actuators to create a ubiquitous technological layer, able to interact transparently with the users, observing and interpreting their actions and intentions, learning their preferences and adjusting the parameters of the system to improve their quality of life and work. This book provides a comprehensive review of the technologies and applications for AAL. Topics covered include the current state of the art of smart environments and labs from an AAL point of view; ambient and wearable sensors for human health monitoring; computer vision for active and assisted living; data fusion for identifying lifestyle patterns; interoperable enhanced living environments; reasoning systems for AAL; person-environment interaction; data analytics for enabling connected health; human gait analysis for frailty detection; fall prevention and detection; supporting activities of daily living; outdoor mobility assistance; location and orientation technologies based on WiFi systems; health, wellbeing and engagement in life through AAL; tablet-based clinical decision support system for hospitalised older adults; smart, age-friendly cities and communities; privacy and ethical issues; and human-centred design. The book concludes with a case study on the design and implementation of a smart home technological platform for the delivery of AAL services. With a wide range of chapters from international contributors, this book is essential reading for researchers and students in academics and industry developing AAL technologies, healthcare practitioners, and engineers with an interest in the field.

There is a need for comprehensive books that provide crucial information in a clear and direct manner, particularly in the medical field. Currently, there are limited resources available to students and clinicians that provide step-by-step procedures with pictures and videos on how to examine the eye in the pediatric population. The Pediatric Eye Exam Quick Reference Guide: Office and Emergency Room Procedures is a clinical procedure book to provide step-by-step pediatric eye care examination techniques and is an important addition to the field of eye care. The chapters are written by leading pediatric optometrists and ophthalmologists in the field. Years of academic and clinical experiences from schools of optometry, hospital-based eye care, and private practice are all presented in a user-friendly format with clinical pearls and insights that will help any clinician perform a pediatric eye exam easily and efficiently. Covering a range of critical topics such as pupil examination, visual field testing, refraction, and ocular emergencies and providing pictures and videos, it is ideal for all students, residents, academicians, trainers, and novel and seasoned clinicians who are interested in learning how to examine a pediatric patient and staying on top of the latest pediatric eye care procedures.

Addiction takes many forms and has the potential to impact individuals of all ages, socio-economic statuses, and ethnic backgrounds. Technology addiction has become one of the latest topics of interest among researchers and mental health professionals as individuals become more engrossed in and reliant on digital devices. Psychological and Social Implications Surrounding Internet and Gaming Addiction focuses on the dark side of technology and the ways in which individuals are falling victim to compulsive internet use as well as gaming and gambling addictions. Highlighting socio-cultural, psycho-social, and techno-cultural perspectives on problematic technology use, this critical publication is essential to the research and practical needs of therapists, public administrators, psychologists, students, and researchers interested in compulsive disorders, human behavior, dependency, and other key mental health issues. A pivotal addition to the current mental health research available, this book focuses on topics including, but not limited to, digital addiction, gaming addiction disorder, gambling, gamification, hypermedia seduction theory, MMORPGs, psychotherapy, and related public policy issues.

Nicotine Use in Mental Illness and Neurological Disorders, a volume in the International Review of Neurobiology series, is a comprehensive overview of the state-of-the-art research into nicotine use in mental illness and neurological disorders. It reviews current knowledge and understanding, also provides a starting point for researchers and practitioners entering the field.

Analytical Ultracentrifugation, the latest volume in Methods in Enzymology, focuses on analytical ultracentrifugation. The scope of this technique has greatly expanded in recent years due to advances in instrumentation, algorithms and software. This volume describes the latest innovations in the field and in the applications of analytical ultracentrifugation in the analysis of macromolecules, macromolecular assemblies, and biopharmaceuticals.

In Changing Course, the best-selling sequel to It Will Never Happen to Me, Claudia Black extends a helping hand to individuals working through the painful experience of being raised with addiction in the family. ""How do you go from living according to the rules - Don't Talk, Don't Trust, Don't Feel - to a life where you are free to talk and trust and feel?"" Dr. Black asks. ""You do this through a process that teaches you to go to the source of those rules, to question them, and to create new rules of your own,"" she explains. Using charts, exercises, checklists, and real-life stories of adult children of alcoholics, Dr. Black guides readers in healing from the fear, shame, and chaos of addiction.

In rural Mexico, people often say that Alzheimer's does not exist. ""People do not have Alzheimer's because they don't need to worry,"" said one Oaxacan, explaining that locals lack the stresses that people face ""over there"" - that is, in the modern world. Alzheimer's and related dementias carry a stigma. In contrast to the way elders are revered for remembering local traditions, dementia symbolizes how modern families have forgotten the communal values that bring them together. In Caring for the People of the Clouds, psychologist Jonathan Yahalom provides an emotionally evocative, story-rich analysis of family caregiving for Oaxacan elders living with dementia. Based on his extensive research in a Zapotec community, Yahalom presents the conflicted experience of providing care in a setting where illness is steeped in stigma and locals are concerned about social cohesion. Traditionally, the Zapotec, or ""people of the clouds,"" respected their elders and venerated their ancestors. Dementia reveals the difficulty of upholding those ideals today. Yahalom looks at how dementia is understood in a medically pluralist landscape, how it is treated in a setting marked by social tension, and how caregivers endure challenges among their families and the broader community. Yahalom argues that caregiving involves more than just a response to human dependency; it is central to regenerating local values and family relationships threatened by broader social change. In so doing, the author bridges concepts in mental health with theory from medical anthropology. Unique in its interdisciplinary approach, this book advances theory pertaining to cross-cultural psychology and develops anthropological insights about how aging, dementia, and caregiving disclose the intimacies of family life in Oaxaca.