Typically, manuals of pediatric hematology-oncology are written by specialists from high-income countries, and usually target an audience with a sub-specialist level of training, often assisted by cutting-edge diagnostic and treatment facilities. However, approximately 80% of new cases of cancer in children appear in mid- and low-income countries. Almost invariably, general practitioners or general pediatricians without special training in oncology will look after children with malignancies who enter the health care system in these countries. The diagnostic facilities are usually limited, as are the treatment options. The survival figures in these conditions are somewhere below 20%, while in high-income countries they are in the range of 80% for many childhood cancers. Pediatric Hematology-Oncology in Countries with Limited Resources is the only book of its kind to provide specific guidance applicable to limited resource settings and builds up from the foundation of general practitioner or general pediatrician competence. Written and edited by leaders in the field, this manual educates physicians on the essential components of the discipline, filtered through the experience of specialists from developing countries, with immediate applicability in the specific healthcare environment in these countries.

The Guest Editors have invited top experts in their fields to write current state-of-the-art clinical reviews on retinopathy of prematurity. Articles are devoted to incidence, the biology of ROP, How Knowledge of the Pathogenesis Continues to Guide Treatment, The Challenge of Screening Using Tele-Ophthalmology, Algorithms for Detection of ROP Based on Weight Gain, Current and Future Treatment of ROP, Setting Up an ROP Program - Interaction of Neonatology, Nursing and Ophthalmology, ROP and the Oxygen Conundrum: Lessons from Recent Randomized Trials, OCT in ROP-Looking Beyond the Vessels, Outcome of ROP. A special article is devoted to outcomes from the 3rd World ROP Congress (Oct 14-16, 2012).

This book provides an overview of the field of Equine-Assisted Therapy and Learning and gives a powerful account of a research study charting the experiences of seven 'at-risk' young people attending a pioneering Therapeutic Horsemanship centre in the UK. The book includes a foreword from Leif Hallberg, author of Walking the Way of the Horse .

This issue of Nursing Clinics of North America, Guest Edited by Patricia Burkhart, PhD, RN, at University of Kentucky, will focus on Pediatrics. Article topics will include: adolescent risky behavior, diabetes, abusive head trauma, obesity and asthma, preventive care, disaster care for school children.

The child is neither an adult miniature nor an immature human being: at each age, it expresses specific abilities that optimize adaptation to its environment and development of new acquisitions. Diseases in children cover all specialties encountered in adulthood, and neurology involves a particularly large area, ranging from the brain to the striated muscle, the generation and functioning of which require half the genes of the whole genome and a majority of mitochondrial ones. Human being nervous system is sensitive to prenatal aggression, is particularly immature at birth and development may be affected by a whole range of age-dependent disorders distinct from those that occur in adults. Even diseases more often encountered in adulthood than childhood may have specific expression in the developing nervous system. The course of chronic neurological diseases beginning before adolescence remains distinct from that of adult pathology - not only from the cognitive but also motor perspective, right into adulthood, and a whole area is developing for adult neurologists to care for these children with persisting neurological diseases when they become adults.

Just as pediatric neurology evolved as an identified specialtyas the volume and complexity of data became too much for the general pediatician or the adult neurologist to master, the discipline has now continued to evolve into somany subspecialties, such as epilepsy, neuromuscular disease, stroke, malformations, neonatal neurology, metabolic diseases, etc., that the general pediatric neurologist no longer can reasonably possess in-depth expertise in all areas, particularly in dealing with complex cases. Subspecialty expertisethus is provided to some traineesthrough fellowship programmes following a general pediatric neurology residency and many of these fellowships include training in research.

Since the infectious context, the genetic background and medical practice vary throughout the world, this diversity needs to be represented in a pediatric neurology textbook. Taken together, and although brain malformations (H. Sarnat & P. Curatolo, 2007) and oncology (W. Grisold & R. Soffietti) are covered in detail in other volumes of the same series and therefore only briefly addressed here, these considerations justify the number of volumes, and the number of authors who contributed from all over the world. Experts in the different subspecialties also contributed to design the general framework and contents of the book. Special emphasis is given to the developmental aspect, and normal development is reminded whenever needed - brain, muscle and the immune system. The course of chronic diseases into adulthood and ethical issues specific to the developing nervous system are also addressed.
*A volume in the Handbook of Clinical Neurology series, which has an unparalleled reputation as the world's most comprehensive source of information in neurology.
*International list of contributors including the leading workers in the field.
*Describes the advances which have occurred in clinical neurology and the neurosciences, their impact on the understanding of neurological disorders and on patient care."

The child is neither an adult miniature nor an immature human being: at each age, it expresses specific abilities that optimize adaptation to its environment and development of new acquisitions. Diseases in children cover all specialties encountered in adulthood, and neurology involves a particularly large area, ranging from the brain to the striated muscle, the generation and functioning of which require half the genes of the whole genome and a majority of mitochondrial ones. Human being nervous system is sensitive to prenatal aggression, is particularly immature at birth and development may be affected by a whole range of age-dependent disorders distinct from those that occur in adults. Even diseases more often encountered in adulthood than childhood may have specific expression in the developing nervous system. The course of chronic neurological diseases beginning before adolescence remains distinct from that of adult pathology - not only from the cognitive but also motor perspective, right into adulthood, and a whole area is developing for adult neurologists to care for these children with persisting neurological diseases when they become adults.

Just as pediatric neurology evolved as an identified specialtyas the volume and complexity of data became too much for the general pediatician or the adult neurologist to master, the discipline has now continued to evolve into somany subspecialties, such as epilepsy, neuromuscular disease, stroke, malformations, neonatal neurology, metabolic diseases, etc., that the general pediatric neurologist no longer can reasonably possess in-depth expertise in all areas, particularly in dealing with complex cases. Subspecialty expertisethus is provided to some traineesthrough fellowship programmes following a general pediatric neurology residency and many of these fellowships include training in research.

Since the infectious context, the genetic background and medical practice vary throughout the world, this diversity needs to be represented in a pediatric neurology textbook. Taken together, and although brain malformations (H. Sarnat & P. Curatolo, 2007) and oncology (W. Grisold & R. Soffietti) are covered in detail in other volumes of the same series and therefore only briefly addressed here, these considerations justify the number of volumes, and the number of authors who contributed from all over the world. Experts in the different subspecialties also contributed to design the general framework and contents of the book. Special emphasis is given to the developmental aspect, and normal development is reminded whenever needed - brain, muscle and the immune system. The course of chronic diseases into adulthood and ethical issues specific to the developing nervous system are also addressed.
*A volume in the Handbook of Clinical Neurology series, which has an unparalleled reputation as the world's most comprehensive source of information in neurology.
*International list of contributors including the leading workers in the field.
*Describes the advances which have occurred in clinical neurology and the neurosciences, their impact on the understanding of neurological disorders and on patient care."

The child is neither an adult miniature nor an immature human being: at each age, it expresses specific abilities that optimize adaptation to its environment and development of new acquisitions. Diseases in children cover all specialties encountered in adulthood, and neurology involves a particularly large area, ranging from the brain to the striated muscle, the generation and functioning of which require half the genes of the whole genome and a majority of mitochondrial ones. Human being nervous system is sensitive to prenatal aggression, is particularly immature at birth and development may be affected by a whole range of age-dependent disorders distinct from those that occur in adults. Even diseases more often encountered in adulthood than childhood may have specific expression in the developing nervous system. The course of chronic neurological diseases beginning before adolescence remains distinct from that of adult pathology - not only from the cognitive but also motor perspective, right into adulthood, and a whole area is developing for adult neurologists to care for these children with persisting neurological diseases when they become adults.

Just as pediatric neurology evolved as an identified specialty as the volume and complexity of data became too much for the general pediatician or the adult neurologist to master, the discipline has now continued to evolve into somany subspecialties, such as epilepsy, neuromuscular disease, stroke, malformations, neonatal neurology, metabolic diseases, etc., that the general pediatric neurologist no longer can reasonably possess in-depth expertise in all areas, particularly in dealing with complex cases. Subspecialty expertise thus is provided to some trainees through fellowship programmes following a general pediatric neurology residency and many of these fellowships include training in research.

Since the infectious context, the genetic background and medical practice vary throughout the world, this diversity needs to be represented in a pediatric neurology textbook. Taken together, and although brain malformations (H. Sarnat & P. Curatolo, 2007) and oncology (W. Grisold & R. Soffietti) are covered in detail in other volumes of the same series and therefore only briefly addressed here, these considerations justify the number of volumes, and the number of authors who contributed from all over the world. Experts in the different subspecialties also contributed to design the general framework and contents of the book. Special emphasis is given to the developmental aspect, and normal development is reminded whenever needed - brain, muscle and the immune system. The course of chronic diseases into adulthood and ethical issues specific to the developing nervous system are also addressed.
*A volume in the Handbook of Clinical Neurology series, which has an unparalleled reputation as the world's most comprehensive source of information in neurology.
*International list of contributors including the leading workers in the field.
*Describes the advances which have occurred in clinical neurology and the neurosciences, their impact on the understanding of neurological disorders and on patient care."

Dr. Wheeler is providing a much needed update on the topic of critical care medicine for the pediatrician. He organized the issue to give a full overview on those topics that most pertinent to practicing clinicians. His authors are top experts in their fields, and they are writing clinical reviews devoted to The Evolving Model of Pediatric Critical Care, The High Reliability Pediatric Intensive Care Unit, Telemedicine and the Pediatric Intensive Care Unit, Resuscitation and Stabilization of the Critically Ill Child, Monitoring and Management of Acute Respiratory Failure, Monitoring and Management of Shock, Cardiac Intensive Care, Monitoring and Management of Acute Kidney Injury, Critical Care of the Bone Marrow Transplant Patient, Neurocritical Care, Ethics and End-of-Life Care, Delirium in the Pediatric Intensive Care Unit, and Family-centered Care in the Pediatric Intensive Care Unit.

This issue reviews the state of the art in pediatric demyelinating diseases. Articles cover topics on childhood transverse myelitis, neuromyelitis optica, multiple sclerosis, acute demyelinating encephalopathy, and more.

This issue of Critical Care Clinics edited by Dr. Margaret Parker on Pediatric Critical Care features topics such as:1. Acute Respiratory Failure, Post-op Cardiac Surgery, Septic Shock, Acute Renal Failure, Traumatic Brain Injury, Encephalitis, Status Asthmaticus, Status Epilepticus, Bleeding/coagulopathy, and Transfusi

Dr. John's vision for this issue is to provide an update to general pediatricians on infectious diseases of importance to them in clinical practice. These include infections that are commonly seen, emerging infectious diseases and infections that are infrequent but can be severe, and so are worth knowing about. As noted in the title, the focus of the issue is on advances in evaluation, diagnosis and treatment of these illnesses. Articles are devoted to bacterial infections, drug-resistant infections, neonatal infectious diseases, rickettsial disease, parasitic diseases, and global infectious diseases.

This entry in the series Pediatric Cancer offers comprehensive information on a variety of cancers, concentrating on brain tumors, the most common solid tumors and the leading cause of cancer-related mortality in children. The contents are organized in seven sections: Neuroblastoma, Medulloblastoma, Leukemia, Lymphoma, Rhabdoid, Sarcoma and Miscellaneous Tumors. Coverage includes pediatric medulloblastoma, and treatments including craniospinal radiation followed by adjuvant chemotherapy. The contributors explain diagnosis and chemotherapy of children with acute lymphoblastic leukemia, and diagnosis of bone marrow involvement in pediatric lymphoma patients. Ewing's sarcoma, a highly malignant connective tissue neoplasm formed by the proliferation of mesenchymal cells, receives extensive coverage, including targeting of molecular pathways and chemotherapy and surgical treatment. The roles of apoptotic genes, MYCN gene, MDM2, and SNP309, P13K inhibitors, alternative splicing and microRNAs, activated leukocyte cell adhesion molecule and inhibition by alu-like RNA in neuroblastoma are discussed in detail. The book explores the molecular genetics, diagnosis, prognosis and therapy of the atypical teratoid/rhabdoid tumor (AT/RT). Among the most common malignant neoplasms in children, AT/RT exhibits similarities with other CNS tumors, which can lead to misclassification, as pointed out in the book. The contributors discuss diagnosis of AT/RT type using imaging technology, and describe new strategies, including intensive multimodal therapy and high dose chemotherapy with autologous stem cell transplantation that have shown improved outcomes. Coverage of therapies includes total resection followed by aggressive chemotherapy and radiation. Discussion includes diagnosis and treatment of other pediatric tumors including adrenocortical tumors, supratentorial primitive neuroectodermal tumors, giant midline tumors, gastrointestinal stromal tumors, ependymomas and intramedullary cavernoma. Pediatric Cancer: Diagnosis, Therapy and Prognosis, Volume 4 includes contributions by ninety-one contributors - oncologists, neurosurgeons, physicians, research scientists and pathologists - representing thirteen countries. The editor, M.A. Hayat, is a Distinguished Professor in the Department of Biological Sciences at Kean University, Union, New Jersey, USA.

This important topic in perinatology is getting its own issue for the first time. The Guest Editors have taken care to provide a full clinical overview in this issue. Articles are devoted to Feeding Practices and NEC; Prebiotics, Probiotics and Postbiotics; Clinical Presentations of NEC; Short Gut Syndrome in the NICU; NEC in Full-term Neonates; Lactoferrin and NEC; Altered Gut Microbiome and NEC; Inflammatory Signaling in NEC; Newer Monitoring Techniques (such as Near-Infrared Spectroscopy) to Determine the Risk of NEC; Surgical Treatment of NEC; Biomarkers of NEC; Intestinal Transplantation.

This work discusses all aspects of the effects of spina bifida and hydrocephalus on the foetus, the child, and the adolescent. Chapters review current neurosurgical techniques, perinatal death and malformation, together with the effects of spina bifida and hydrocephalus on behavior and education. The book thus presents an up-to-date view on the current diagnosis, investigation, and treatment of these two conditions.

The Guest Editors have assembled an international list of top experts to present the most current information to pediatricians about patient safety. The issue has a primarily clinical focus with a few articles addressing the business and practice of patient safety. Articles are devoted to the following topics: Developing performance standards and expectations for safety; The role of CPOE in patient safety; The role of smart infusion pumps on patient safety; Abstracted detection of adverse events in children; The role of effective communication (including handoffs) in patient safety; Reducing mortality resulting from adverse events; Optimizing standardization of case reviews (morbidity and mortality rounds) to promote patient safety; Impact of (resident) duty work hours on patient safety; Role of simulation in safety; The role of diagnostic errors in patient safety; The role of collaborative efforts to reduce hospital acquired conditions; Patient safety in ambulatory care; Role of FDA and pediatric safety; and Patient safety through the eyes of a parent.

The Guest Editors have invited authors who are well published on the current research for breastfeeding. The issue will update practicing pediatricians and other child health professionals on the current state of knowledge and practice in breastfeeding management and support. It has been more than ten years since the last issues on breastfeeding published; because those issues were popular and widely cited, it is expected that this issue will also become a valuable resource. The articles in this issue will provide pediatricians and other child health professionals with a timely update and critical new information to advocate for breastfeeding and support the breastfeeding mother-infant dyad.

Modeled on the author's bestselling "Therapist s Guide to Clinical Intervention, "this new book on child clinical interventionpresents much of the material in outline or bullet point format, allowing easy understanding of complex material for the busy therapist. This clinician s guide to diagnosing and treating disorders in children includes definitions of the disorder, diagnostic criteria, the neurobiology of the disorder, information on functional impairment, treatment planning, and evidence-based interventions. The book additionally offers adjunctive skill building resources to supplement traditional therapy choices as well as forms for use in clinical practice.
Outlines treatment goals and objectives for diagnosis Discusses interventions and the evidence basis for each Offers skill building resources to supplement treatment Provides business and clinical forms for use with child patients "

Clinics in Developmental Medicine No. 178

For most children with cerebral palsy, the extent to which they can use their hands is critical to their overall development. Over the last two decades there have been major advances in the understanding of hand function. Particularly in children with cerebral palsy, assessment of hand function has become more exact and the range of possible interventions has expanded. Changes in treatment approaches can be seen in neurorehabilitation, orthopaedic management, developmental pediatrics and rehabilitation including occupational and physical therapy practices.In this book, selected experts from around the world in the fields of neuroimaging, neurology, orthopaedics, anatomy, motor control and motor learning provide fundamental theoretical information for the development of hand function in children with cerebral palsy. The book also shows how theory can be translated into practice by clinicians who provide assessment and intervention services to improve hand use in this population in sections written by researchers in occupational and physical therapy. Linking different fields of knowledge, this book highlights new perspectives and provides the best evidence for different types of intervention. By focusing only on hand function this essential book highlights new concepts for clinicians and others working towards the overall well-being of children with cerebral palsy.

The Guest Editors have assembled well published authors to present state-of-the-art clinical reviews devoted to resuscitation of the newborn and fetus. Articles are devoted to the following topics: fetal/intrauterine compromise; Cellular biology of end organ injury and strategies to prevent end organ injury; Role of oxygen in the DR; DR management of meconium stained infant; Role of medications in neonatal resuscitation; Delayed cord clamping; Post-resuscitation management; HIE and novel strategies for neuroprotection; Physiology of transition from intrauterine to extrauterine life; Resuscitation of preterm infants: Special considerations; Chest compressions and dysrhythmias in neonates; Resuscitation of infants with prenatally diagnosed anomalies; Ethical issues in neonatal resuscitation; Training programs in neonatal resuscitation: The Neonatal Resuscitation Program and Helping Babies Breathe; and Future of neonatal resuscitation.

"Play Therapy: Treatment Planning and Interventions: The Ecosystemic Model and Workbook, 2e," provides key information on one of the most rapidly developing and growing areas of therapy. Ecosystemic play therapy is a dynamic integrated therapeutic model for addressing the mental health needs of children and their families. The book is designed to help play therapists develop specific treatment goals and focused treatment plans as now required by many regulating agencies and third-party payers. Treatment planning is based on a comprehensive case conceptualization that is developmentally organized, strength-based, and grounded in an ecosystemic context of multiple interacting systems.

The text presents guidelines for interviewing clients and families as well as pretreatment assessments and data gathering for ecosystemic case conceptualization. The therapist's theoretical model, expertise, and context are considered. The book includes descriptions of actual play therapy activities organized by social-emotional developmental levels of the children. Any preparation the therapist may need to complete before the session is identified, as is the outcome the therapist may expect. Each activity description ends with a suggestion about how the therapist might follow up on the content and experience in future sessions. The activity descriptions are practical and geared to the child. Case examples and completed sections of the workbook are provided. It provides the therapist with an easy-to-use format for recording critical case information, specific treatment goals, and the overall treatment plan. Workbook templates can be downloaded and adapted for the therapist's professional practice.
Presents a comprehensive theory of play therapyClearly relates the theoretical model to interventionsProvides examples of the application of both the theory and the intervention model to specific casesDescribes actual play therapy activitiesWorkbook format provides a means of obtaining comprehensive intake and assessment dataCase examples provided throughout"

This book is one of four publications intended to engage a broad range of persons in informed decision-making regarding key health and human value questions. Each publication has a usefulness of its own, while all four comprise a convenient series.

The Year Book of Neonatal and Perinatal Medicine brings you abstracts of the articles that reported the year's breakthrough developments in neonatal and perinatal medicine, carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. There's no faster or easier way to stay informed Chapters in this annual cover the most current information on all aspects of neonatal and perinatal medicine from genetics to labor and delivery to issues related to many key bodily systems (heart, respiratory, nervous system, etc.) of newborns. Other topics for 2004 include neurology, gastroenterology and nutrition, medical disorders of pregnancy, fetal evaluation, and neonatal behavior.

The application of neurophysiological examination techniques to the newborn infant has increased considerably in recent years. This book gives an up-to-date description of these techniques, and evaluates their importance in the care of newborn babies.

This issue of Endocrinology and Metabolism Clinics provides essential updates across the spectrum of pediatric endocrinology. Topics covered include Prevention of type 1 and type 2 diabetes mellitus; genetics of growth; diagnosis in prepubescent girls; Turner and Noonan Syndromes; thyroid function in Down Syndrome; chronic disease; effects of ADHD treatment on growth; Vitamin D and bone health; use of statins; and obesity prevention.

A comprehensive review of pediatric surgery for the general surgeon Topics include pediatric pain management, hernias, hydroceles, and undescended testes, appendectomy, merckel's and intussusceptions, pyloric stenosis, childhood obesity, neonatal bowel obstruction, short gut syndrome and vascular access, abdominal wall reconstruction, gastroesophageal reflux disease, pediatric chest, CDH and protective ventilation strategies, chest wall deformities, congenital and pediatric neck lesions, vascular and lymphatic malformations, pediatric malignancies, teratoma and ovarian lesions, and more