This book describes control of ventilation during sleep in both health and disease states. The topics are presented in a fashion that can be easily comprehended with many figures to illustrate complex concepts. Thus, a wide range of topics, starting from the site of normal respiratory rhythm generation to chemoreceptor control of sleep apnea, description of the apneic threshold, pathophysiology of upper airway closure, novel techniques to measure control of breathing, effect of cerebral blood flow on breathing, effect of opioids on ventilation, effect of heart failure on ventilation, genetic aspects of breathing disorders, age and gender differences, and various therapies are discussed. Key Features * Helps to bridge the gap between straight forward physiology and clinical practice through a range of topics and use of case vignettes * Explores various aspects of clinical management and control which is beneficial to sleep clinicians, respiratory physiologists, intensivists, trainees, and researchers. * Distills complex concepts into understandable language and figures, providing helping resource to the clinicians, that transforms a dry topic vis a viz control of ventilation into an exciting understandable 'clinician' language.

This book is devoted solely to the tricuspid valve and its role in congenital heart disease. Tricuspid valve anomalies are part of the pathological spectrum in various congenital heart diseases, including Ebstein anomaly and tricuspid valve dysplasia, with different pathophysiology and clinical implications. This book covers all relevant aspects of such anomalies, including diagnosis, therapy and follow-up. Further topics addressed include the way in which the tricuspid valve may become the "systemic" valve in some congenital diseases, with important consequences and the involvement of the tricuspid valve in the right-sided heart complications often seen in adults with congenital heart disease. All of the chapters are written by internationally recognized experts and are designed to deliver state of the art knowledge of practical value. This book will be an important addition to the library for surgeons, cardiologists and other practitioners involved in the management of patients with congenital heart disease.

The book presents a problem-based, rational approach to the diagnosis of orthopaedic problems in children. It is divided into four sections based on the age at which specific problems may be encountered; the newborn and infant, the toddler and the pre-school child, the child in the school-going age and the adolescent. The authors outline a systematic approach to arrive at a tentative diagnosis by asking relevant questions related to the presenting symptom and then performing a thorough clinical examination. They then suggest the most appropriate investigations to confirm the diagnosis. Each chapter deals with the common conditions that may lead to the problem; the rarer causes of the problem are listed at the end. This feature would make the book a practical manual and a high quality reference source. An important feature of the book is the number and quality of illustrations and video clips in the electronic version.

Book covers course with topics in infectious diseases in children and is intended for Pediatric Infectious disease clinical researchers, trainees, trainers, and all those who manage the research of children with infections and the children themselves. The conference is being supported by several societies and is sponsored by several pharmaceutical companies, such as Aventis, Baxter, Chiron Vaccines, Wyeth, etc. ToC reflects the scientific program found here: http: //www.oxfordiic.org/#course

This book from experienced paediatricians Professor Alf Nicholson and Professor Kevin Dunne covers the essential elements needed throughout the career of those who treat children and adolescents. Based on the current paediatric training curriculum, this book includes the core basics (section 1), the various symptom-based presentations (section 2) all with input from renowned sub-specialists in Paediatrics, the common presentations relating to age that are seen in primary care (section 3) and the skills you need to have to be a successful trainee or consultant in Paediatrics (section 4). All of the chapters have high quality clinical and radiology images as appropriate and have additional typical case scenarios to highlight the learning points. This book is unique in that it caters for undergraduate students through to postgraduate trainees in paediatrics or general practice, and the working GP or consultant. Clinical vignettes to highlight key learning points Over 90 case scenarios sprinkled throughout the book with clinical pearls, interpretation of investigations and pitfalls to avoid for each scenario List of key points to be obtained from a consultation to support doctors in the clinic All key procedures in neonatology and paediatrics are covered Problem-solving practice to test knowledge Section 4 hosts unique chapters not least safe practice, dealing with uncertainty, the avoidance of errors, ethical dilemmas, ECG and laboratory interpretation of results, neonatal and paediatric procedures and critical journal reading High-quality clinical pictures, cardiac pictures, ECGs and radiology images to support learning Content suitable for students, GPs and specialists 20 podcasts available in the e-book version

For more than 30 years, the highly regarded Secrets Series (R) has provided students and practitioners in all areas of health care with concise, focused, and engaging resources for quick reference and exam review. Written by Drs. Richard A. Polin and Mark F. Ditmar, Pediatric Secrets, 7th Edition, features the Secrets' popular question-and-answer format that also includes lists, tables, pearls, memory aids, and an easy-to-read style - making inquiry, reference, and review quick, easy, and enjoyable. The proven Secrets Series (R) format gives you the most return for your time - succinct, easy to read, engaging, and highly effective. Fully revised and updated throughout, including protocols and guidelines that are continuously evolving and that increasingly dictate best practices. Practical, up-to-date coverage of the full range of essential topics in the practice of pediatrics. Top 100 Secrets and Key Points boxes provide a fast overview of the secrets you must know for success in practice and on exams. Features bulleted lists, mnemonics, practical tips from leaders in the field - all providing a concise overview of important board-relevant content. Portable size makes it easy to carry with you for quick reference or review anywhere, anytime. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

2015 BMA Medical Book Awards Highly Commended in Paediatrics Category! Neonatal and Infant Dermatology is a unique comprehensive and heavily illustrated reference on the dermatologic diseases of newborns and infants. It includes discussions of common and uncommon conditions seen in infants at birth and in the first few months of life. With over 600 superb photographs of normal and abnormal skin conditions including images of rare conditions, this easily accessible resource is essential for pediatricians, neonatologists, and dermatologists as well as other healthcare professionals involved in the diagnosis and treatment of dermatologic diseases in infants and newborns. "...Neonatal and Infant Dermatology is far more than an atlas. It is a state-of-the-art presentation of the diagnosis and management of skin disorders, and a road map for future interventions to enhance the well-being of the newborn infant." Foreword by: Richard A. Polin, June 2014 Get the depth of coverage you need to effectively diagnose skin conditions in neonates and infants. Expedite effective differential diagnoses with guidance from algorithms, lists, text, boxes and supporting images. Benefit from the experience of over 60 contributors from around the world lead by Drs. Lawrence F. Eichenfield and Ilona J. Frieden, two of the most important names in the fields of dermatology and pediatrics. Glean all essential, up-to-date, need-to-know information with new chapters on Papulosquamous and Lichenoid Disorders, Acneiform and Sweat-gland disorders and two individual chapters on Vascular Malformations and Vascular Tumors. See what to expect and how to proceed with new, high-quality illustrations and photos that provide even more visual examples of abnormal and normal conditions. Take it with you anywhere! Access the full text, image library, and more online at Expert Consult.

+Case-based format enhances learning and retention of core curriculum in pediatric orthopaedics +Reflects pediatric orthopaedic diagnosis and management on a global basis +Concise text and numerous illustrations aid understanding of a broad spectrum of cases +Includes access to additional material via the e-book for those readers requiring more in depth content.

In recent years there has been an increase in research into childhood depression, and it is now recognised that depression can severely impair young people in many aspects of their life, school, peer and social relationships, and frequently persists into adulthood.

Depression: Cognitive Behaviour Therapy with Children and Young People provides an accessible guide to recognising and treating depression in young people. Based on a successful manual developed for research trials, this book presents an overview of a cognitive behavioural model for working with this age group, as well as practical ideas about how to start therapy. Topics covered include:

• engaging young people
• setting goals for therapy
• cognitive behaviour assessment and formulation
• solutions for problems practitioners may face
• encouraging parents and agencies to support therapy.

Depression includes case examples and practical tips to prepare the practitioner for working with young people. Information is presented in a readable and practical style making this book ideal for professionals working in child and adolescent mental health services, as well as those in training. It will also be a useful guide for people working in community services for young people.

Online resources:

The appendices of this book contain worksheets that can be downloaded free of charge to purchasers of the print version. Please visit the website to find out more about this facility

This innovative book for Neonatal Nurses and NICU clinicians provides evidence-based clinical guidelines proven to mitigate and reduce the often profound trauma experience and subsequent developmental challenges for vulnerable hospitalized infants and their families. Each in-depth guideline includes the latest scientific research explaining the clinical rationale for the recommended practices, associated short-term and long-term outcomes, and implementation strategies to support practice improvement. The text reflects a trend - the provision of trauma-informed care in the neonatal intensive care unit - that has recently gained increasing momentum. With endorsements by respected transdisciplinary neonatal clinicians, it provides guidelines that encompass the five core measures for age-appropriate care, including the Healing Environment, Pain and Stress, Protected Sleep, Activities for Daily Living, Age-Appropriate Infant Guided Feeding, and Family-Integrated Care. The book also features downloadable sample competencies and parent teaching guides, along with additional eLearning modules with Nursing CE. A self-assessment checklist and teaching sheets, sample competencies, and sample algorithms add to the book's utility. Key Features:Provides clinically relevant, evidence-based practice guidelines for minimising trauma in neonates.Encompasses the five core measures for age-appropriate care.Includes proven implementation strategies to facilitate practice transformation.Offers downloadable sample competencies and parent teaching guides and eLearning modules with Nursing CE.Reviewed and endorsed by transdisciplinary neonatal clinicians.

Originally published in 1975, this book traces the problems which arise for families coping with a chronic childhood disease - cystic fibrosis. The discussion of these problems is important for the families of other seriously ill or disabled children, all of whom are faced with similar implications of their situation. The book looks at the stressful situations which face them: mastering the child's treatment technique, assisting them to come to terms with their disease. It deals with the practical problems which arise for the parents and siblings of a sick child and explores the profound repercussions of the loss of a child on the entire family, considering the ways in which many of these families managed to transcend their problems.

Originally published in 1974, and written by paediatricians, social workers, nurses and a parent who cared for her dying child, this book is concerned with pinpointing the problems which exist for parents and those involved in the care of sick children, both in terms of accepting the facts of a child's illness, and in loving supporting and giving them maximum enjoyment within the limits of their condition. The fears and anxieties of such children are examined - separation from parents, fear of pain, an increasing sense of difference and in some cases a very real appreciation of their situation. All these limit the child's happiness, and ways of counteracting them are suggested. Similarly the distress of parents and of medical advisers is discussed.

In Stories from Child & Adolescent Psychotherapy author Henry Kronengold explores the unpredictable world of child and adolescent psychotherapy through a series of engaging and innovative clinical vignettes. The ups, downs, and dilemmas of therapeutic work are considered in each realistic narrative as readers are offered a unique view of what happens between the therapist and child, as well as the therapist's own process during the therapy. This captivating new resource is intended to spark a conversation within the reader, regardless of professional experience, regarding which therapeutic factors are ultimately most helpful to children and adolescents.

Reflecting the increasing interest in fertility management for pediatric and adolescent patients and fulfilling an urgent need to have a comprehensive guide to the management of these individuals, this is the first book of its kind to present a comprehensive discussion of pediatric and adolescent oncofertility. It carefully examines the impact of pediatric cancer and cancer therapy on fertility and presents both current and emerging fertility preservation techniques for both males and females, such as cryopreservation. Fertility concerns beyond cancer are also discussed, including disorders of sexual differentiation, gender dysphoria and thalassemia. Practical chapters on pediatric oncofertility in the clinic round out the book, covering setting up a practice, counseling and consent, disclosure and insurance considerations. Concluding chapters document fertility preservation techniques and outcomes internationally, with contributions from Portuguese, Brazilian and Japanese authors. Timely and wide-ranging, Pediatric and Adolescent Oncofertility is an ideal resource for reproductive medicine specialists, pediatric oncologists, and primary care physicians treating pediatric and adolescent cancer patients looking to protect fertility options.

Over the past decade, significant advances in research methodology have stimulated dramatic progress in the field of child psychiatry in general, and in pediatric anxiety disorders, more specifically. Pediatric Anxiety Disorders: A Clinical Guide is a comprehensive and vital addition to the literature at an exciting time in the field of psychiatry. This state-of-the-art reference aims to bridge the most up-to-date research findings with relevant clinical perspectives, making it a unique and essential resource for established clinicians and researchers, as well as for students and trainees. The book is organized into four sections, each of which includes chapters on a specific area of interest. The first section reviews the current research regarding etiological mechanisms of pediatric anxiety. The second section provides in-depth descriptions of the anxiety disorders that affect children and adolescents. The third section summarizes the literature on empirically supported assessment tools and evidence based cognitive-behavioral and pharmacological interventions. Of special practical note, the authors of these chapters have included comprehensive summary tables that can serve as quick reference tools. The final section of the text is dedicated to understanding how anxiety manifests in two special populations, children with chronic medical illnesses and those with autism spectrum disorders. Pediatric Anxiety Disorders: A Clinical Guide is an authoritative new volume developed by a renowned collection of clinicians and researchers in the field of childhood anxiety disorders.

After 17 years, the Nutricia Symposium retumed to its horne grounds in The of the 10th Nutricia Netherlands, where the first five Symposia were held. The objective Symposium was to bring together a limited number of opinion leaders and key researchers in selected topics of infant nutrition to discuss the current state of the art based on original contributions and reviews. The discussion sessions after the papers were taped and edited and may give additional information and views. As a result of time constraints, the discussions on a few papers had to be cut short, or, unfortunately, could not take place at all. Nevertheless, we strongly recommend reading the discussion sections, such as the panel discussion on the requirements for LCPUFA for term and/or preterm infants. During the preparation of the Symposium the sad news that Professor J . H. P. Jonxis died prompted the organisers to dedicate one special lecture to the memory of the principal organiser of the first four Nutricia Symposia. This lecture entitled "What determines the production and composition ofbreast milk?" was given by Dr. Kathleen Moti . Acknowledgement should be made to the co-organizers and co-chairmen Professor Sir David HuH, Professor Pieter Sauer and Dr. Terence Stephenson for their contri bution. Finally, without mentioning names, the editors wish to thank a number of persons within the Nutricia organization without whom the Symposium and its Pro ceedings would not have been possible."

There are growing questions regarding the safety, quality, risk management, and costs of PCC teams, their training and preparedness, and their implications on the welfare of patients and families. This innovative book, authored by an international authorship, will highlight the best practices in improving survival while paving a roadmap for the expected changes in the next 10 years as healthcare undergoes major transformation and reform. An invited group of experts in the field will participate in this project to provide the timeliest and informative approaches to how to deal with this global health challenge. The book will be indispensable to all who treat pediatric cardiac disease and will provide important information about managing the risk of patients with pediatric and congenital cardiac disease in the three domains of: the analysis of outcomes, the improvement of quality, and the safety of patients.

This handbook covers the most common paediatric problems encountered in Accident and Emergency departments. The contents include cardiopulmonary resuscitation, major trauma, fractures and other orthopaedic problems, burns, scalds and poisoning. Child abuse and its recognition and management are described. Emphasis has been placed on the emergency management of serious illness and injury and on the management of common problems. In many cases, further management is described for those studying for the Accident and Emergency Fellowship examination. This edition includes a revised section on paediatric resuscitation which summarizes the latest guidelines in this area. The section on major trauma has been extended to follow the Advanced Paediatric Life Support guidelines, and the section on fractures is now in tabular format for the comparison of possible diagnoses.

A step-by-step resource for treating more than 40 prevalent issues with proven strategies This comprehensive handbook for evidence-based mental health and learning interventions with children and adolescents is distinguished by its explicit yet concise guidance on implementation in practice. With a compendium of proven strategies for resolving more than 40 of the most pressing and prevalent issues facing young people, the book provides immediate guidance and uniform step-by-step instructions for resolving issues ranging from psychopathological disorders to academic problems. Busy academics, practitioners, and trainees in schools and outpatient clinical settings will find this resource to be an invaluable desktop reference for facilitating well-informed decision-making. Unlike other volumes that ignore or merely reference the evidence base of various interventions, this book focuses on providing immediate, empirically supported guidance for putting these strategies into direct practice. Issues covered include crisis interventions and response, social and emotional issues, academic/learning issues, psychopathological disorders, neuropsychological disorders, and the behavioral management of childhood health issues. Each chapter follows a consistent format including a brief description of the problem and associated characteristics, etiology and contributing factors, and three evidence-based, step-by-step sets of instructions for implementation. Additionally, each chapter provides several websites offering further information about the topic. Featuring contributions from leading scholars and practitioners on each issue covered, this book will be a valuable resource for child clinical and school psychologists, counselors, social workers, and therapists as well as other health and mental health professionals whose primary practice is with children and adolescents. Key Features: Demonstrates step-by-step, evidence-based interventions for more than 40 common childhood issues Provides treatment procedures that can be immediately put into practice Covers a wide range of mental health and academic/learning issues for children and adolescents Relevance for both school-based and clinically-based practice Includes contributions by noted experts in the field

A much-needed overview of the available information now accumulating to indicate that assisted reproductive technologies are generally safe for both babies and mothers. However, the literature abounds with reports of a higher risk of obstetric and perinatal complications; regarding the long term outcomes for both women and children, the data are still scarce. The chapters summarized in this book review the current knowledge on long term safety of assisted reproduction and indicate the need for continued research to cover the lack of data in some specific patient groups and for recently developed treatments that only have a short period of follow-up.

This book provides recommendations for evaluation and therapy in the area of acute pediatric neurology; these are presented didactically with frequent use of illustrations and algorithms. Chapters in the first part of the book discuss presenting symptoms of acute neurological conditions. The second part of the book covers major areas of acute pediatric neurology and each of these chapters has three key elements: description of presenting symptoms; recommended assessments; and recommended interventions. Acute Pediatric Neurology provides an accessible, clinically focused guide to assist physicians in the emergency ward or intensive care unit in decisions on diagnosis and therapeutic interventions in all major acute pediatric neurological diseases.

List of Contributors xviii An Aging Humankind: New Realities E. Dicgalusy Does Menopause Increase the Risk of Coronary Heart Disease? M.V. Huisrnan Chronic Low-Grade Metabolic Acidosis in Normal Adult Humans: Pathophysiology and Consequences L. Frassetto, R.C. Morris, Jr., K. Todd, and A. Sebastian The Menopause, Sex Hormones, and Rheumatic Disease G. Hall Novel Mechanisms of Estrogen Action J.-A. Gustafsson The Action of Ovarian Steroid Hormones on Tissues and Organs M.J. Legato Nongenomic Mechanisms of Sex Hormones J.H.H. Thijssen Action of Specific Estrogens on Vascular Cells C.S. Wingrove and J.C. Stevenson Direct Actions of Estrogen on Vascular Cells Ameliorates Response to hjury D. W. Losordo ix Newer Progestogens G. Samsioe IV. 11. Cardiovascular Disease: Risk Factors Related to Thrombosis G. de Gaetano, M.B. Donati, and L. Iacoviello Estrogen Effect upon Coronary Vasculature G.M.C. Rosano, F. Leonardo, and G. Panina Estrogen and Endothelial Function A. Virdis, L. Ghiadoni, I. Sudano, S. Pinto, S. Taddei, and A. Salvetti Action of Specific Estrogens on the Coronary Artery: Effects on Lipoproteins, Coagulation, and Fibrinolysis J.M. Sullivan Coronary Heart Disease in Women: Status 1998 N. K. Wenger Introduction to Osteoporosis C. Christiansen Genetics of Osteoporosis L. Masi, L. Gennari, A. Falchetti, and M.L. Brandi The Clinical Management of Osteoporosis S.E. Papapou los VI.

A state-of-the-art and concise guide to the clinical management of pediatric endocrine disorders, the second edition of the highly regarded Pediatric Endocrinology: A Practical Clinical Guide covers the most common and challenging conditions seen by practicing endocrinologists and primary care physicians, including growth, hypothalamic, pituitary, adrenal, thyroid, calcium and bone, and reproductive disorders, as well as metabolic syndromes. This expanded second edition includes new topics being seen more commonly in pediatric endocrinology practices related to obesity and type 2 diabetes mellitus and lipid disorders. Each chapter contains an introductory discussion of the problem, a review of the clinical features that characterize it, the criteria needed to establish a diagnosis, and a comprehensive therapy section delineating the risks and benefits of the best therapeutic options available. Invaluable tables summarize the critical factors in etiology, clinical presentation, diagnosis, and therapeutic dosages. Pediatric Endocrinology: A Practical Clinical Guide, Second Edition, is a comprehensive resource for all clinicians concerned with the myriad endocrinologic disorders seen in children and adolescents.

Originally published in 1983, in the two decades prior to publication, specialised neonatal units for the treatment of sick or preterm babies had been set up in most major neonatal centres. In the early years these units did little to prevent separation of parents and babies and evidence accumulated of the ill effects of this situation. In addition, we had gradually become aware of the difficulties of building a relationship with a sick or immature baby even under more ideal circumstances. This book, in a series of authoritative review chapters, sets out to describe the process by which social relationships develop after birth and the ways in which this process may be distorted by separation, the condition of the baby or by the process of medical treatment. Experienced practitioners describe practical steps which may be taken to support parents and foster their relationship with their babies in treatment situations. The final section of the book examines the organisation of neonatal care in a number of widely different settings and indicates that diverse approaches may be successful in achieving the same ends.

Stuart Handwerger, MD and a distinguished panel of clinicians and experts review the most significant recent developments in molecular and cellular biology, powerful advances that have produced new diagnostic methods and improved treatments for many pediatric endocrine diseases. Topics range from the growth hormone/prolactin/placental lactogen gene family and their regulation of growth, to steroid hormones, sexual development, and mineral corticoid action. Additional chapters examine the pathophysiology of insulin-dependent diabetes mellitus, the molecular genetics of thyroid cancer, the molecular basis of hypophosphatemic rickets, and inherited diabetes insipidus. Molecular and Cellular Pediatric Endocrinology offers today's clinicians and researchers not only the latest findings on endocrine diseases in their pediatric manifestations, but also highly practical insights into today's cutting-edge diagnostics, treatment strategies, and powerful new therapeutics.