"Dr. Wakefield sets the record straight. It was not he who showed callous disregard towards vulnerable, sick children with autism. It was the British medical establishment, the General Medical Council, the media and the pharmaceutical industry."-Mary Holland, Esq., co-founder, Elizabeth Birt Center for Autism Law and Advocacy As Andrew Wakefield states in his prologue, "If autism does not affect your family now, it will. If something does not change-and change soon-this is almost a mathematical certainty. This book affects you also. It is not a parochial look at a trivial medical spat in the United Kingdom, but dispatches from the battlefront in a major confrontation-a struggle against compromise in medicine, corruption of science, and a real and present threat to children in the interests of policy and profit. It is a story of how 'the system' deals with dissent among its doctors and scientists." In the pursuit of possible links between childhood vaccines, intestinal inflammation, and neurologic injury in children, Wakefield lost his job in London's Royal Free Hospital, his country of birth, his career, and his medical license. A recent General Medical Council ruling stated that he was "dishonest, irresponsible and showed callous disregard for the distress and pain of children." Maligned by the medical establishment and mainstream media, Wakefield endeavors to set the record straight in Callous Disregard. While explaining what really happened, he calls out the organizations and individuals that are acting not for the sake of children affected by autism, but in their own self-interests.

Multicultural Child Maltreatment Risk Assessment provides detailed descriptions of child maltreatment assessment and key strategies for culturally informed risk assessment in families. The book presents a new model for evaluating families that includes cultural competence, a conceptualization of adequate parenting, and strategies for reflective decision making. Chapters address a range of factors including race, ethnicity, religion, gender, and sexuality. Ten case studies, each including discussion prompts, challenge the reader to apply forensic evaluation techniques for effective and ethical decision making in complex and ambiguous cases. Both experienced mental health providers and students will come away from the book with a deeper understanding of child maltreatment and its effects, models and modes of assessment, and factors that place families at greater risk.

Multicultural Child Maltreatment Risk Assessment provides detailed descriptions of child maltreatment assessment and key strategies for culturally informed risk assessment in families. The book presents a new model for evaluating families that includes cultural competence, a conceptualization of adequate parenting, and strategies for reflective decision making. Chapters address a range of factors including race, ethnicity, religion, gender, and sexuality. Ten case studies, each including discussion prompts, challenge the reader to apply forensic evaluation techniques for effective and ethical decision making in complex and ambiguous cases. Both experienced mental health providers and students will come away from the book with a deeper understanding of child maltreatment and its effects, models and modes of assessment, and factors that place families at greater risk.

Nutrition in Pediatric Pulmonary Disease is a much needed resource for practitioners that provides a basic understanding of nutrition and nutritional supplements; their impact on physiologic function and how this can be applied for general health maintenance as well as a supplemental treatment for pulmonary diseases. This book provides information on (1) basics of nutrition, supplements and herbs and how they influence physiology (2) their application and potential use for various pulmonary diseases along with evidence regarding efficacy and safety. Also examined are (3) how diet, dietary supplements and herbs are integrated together for treatment and prevention of pulmonary disease. Finally (4) several health promoting diets and their potential benefits to patients with pulmonary diseases will be discussed. Nutrition in Pediatric Pulmonary Disease is an excellent new resource for practicing physicians who are interested in incorporating more nutritional approaches to treating their patients.

Written and edited by renowned experts in pediatric anesthesia, Smith's Anesthesia for Infants and Children provides clear, concise guidance on effective perioperative care for any type of pediatric surgery. The 10th Edition contains significantly revised content throughout, bringing you fully up to date with recent advances in clinical and basic science that have led to changes in today's clinical practice. Offers comprehensive coverage of physiology, pharmacology, and clinical anesthetic management of infants and children of all ages. Contains new chapters on Airway Physiology and Development, Normal and Difficult Airway Management, Ultrasound, Acute Pain Management, Chronic Pain Management, Palliative Pain Management, Infectious Diseases, and Education; plus extensively revised content on cardiovascular physiology; induction, maintenance, and recovery; organ transplantation, and more. Features more than 100 video demonstrations, including regional anesthesia videos, echocardiograms of congenital heart lesions, anatomic dissections of various congenital heart specimens with audio explanations, various pediatric surgical operative procedures, airway management, and much more. Provides outstanding visual guidance throughout, including full-color photographs, drawings, graphs and charts, and radiographic images. Includes quick-reference appendices online: drug dosages, growth curves, normal values for pulmonary function tests, and a listing of common and uncommon syndromes. Provides an interactive question bank online for review and self-assessment. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

This title includes a number of Open Access chapters. Childhood obesity is a major public health crisis nationally and internationally. This insightful compendium provides valuable information and assesses the research foundations behind several school initiatives to help combat the epidemic of obesity in children and adolescents, particularly using interventions to increase physical activity. The book looks at the issue from three levels: first, the effects of unhealthy eating and lack of exercise on a number of health outcomes in children and adolescents; second, successful small- and large-scale school-based interventions; and finally, synthesis of current literature and translation into specific guidelines and recommendations. Specific topics addressed in the book include: * The appeal and benefits of outdoor versus indoor activity * Cultural differences in physical activity * Successful interventions and their continued success, or lack of, after several years * The roles of family and community interventions * Staff involvement in children's physical activities * Specific programs, such as Plant Health, an antismoking intervention with unintended obesity intervention * Establishing healthy habits in youth This research provides schools with a strong foundation for implementing policies and practices that support healthy eating and regular physical activity. In the process, educators will be ensuring the best possible chance for increasing students' academic success, improving both physical and mental health, and decreasing the risk for myriad chronic diseases.

Infant, Child and Adolescent Nutrition: A Practical Guide, Second Edition, is an evidence-based, practical guide introducing readers to the theory behind optimal child nutrition. Containing practical advice on how to put that theory into practice, this new edition facilitates learning through case studies, key points, and learning activities. Divided into seven sections, chapters cover prenatal nutrition and nutrition throughout childhood from preterm babies to adolescents up to the age of 18. Sections throughout focus on topics ranging from nutrient requirements, balanced eating patterns and common problems to cultural influences on food choices and guidelines on assessing growth and dietary intakes. Prevention and management of obesity and allergies are covered in separate chapters. The first 1000 days are given particular consideration with chapters on diets for preconception, pregnancy, milk feeding and complementary feeding during infancy. The chapter on nutritional treatments covers common conditions such as diabetes and Crohn's disease, as well as more intricate feeding regimes and tube feeding required for children with rarer diseases and syndromes. New in this second edition are: * Changes in in food allergy prevention and oral immunotherapy treatments. * Causes and management strategies to deal with fussy and selective eating in toddlers. * The importance of iodine in diets before and during pregnancy to improve children's cognitive abilities. * Updated recommendations on vitamin D supplementation. This second edition is an essential reading for students taking courses in nutrition and paediatric healthcare. It serves as a useful reference for individuals responsible for the nutritional intakes of children in primary care and community settings including early years practitioners, midwives, health visitors, school nurses and governors, social workers, paediatricians and general practitioners. About the Author Judy More BSc, RD, RN is a Paediatric Dietitian, Honorary Lecturer at the University of Plymouth, UK and Director of Child-nutrition.co.uk Ltd, London, UK.

Key Features * Covers allergic diseases in general and asthma in detail, providing a comprehensive coverage of clinical features, diagnosis and management, using a case-based approach * Creates awareness of the fundamentals of clinical allergy, helping physicians make wise choices of medical and surgical management, especially in resource limited settings * Features insight from international authors with clinical experience in diagnosis and treatment of asthma in the specific age group of adolescents and young adults.

Increasingly, global humanitarian efforts are focusing on improving the lives of children. And among the developing world, the African nations are particularly affected by extreme weather conditions, devastating pandemics, and armed conflict. Neurocognitive science offers significant avenues toward bringing needed aid to the continent while creating a template for helping children worldwide.

The studies in "Neuropsychology of Children in Africa" clearly illustrate how the brain develops and adjusts in the face of adversity. Contributors span assessment approaches and public health risk factors, and represent established topics and emerging lines of research, including biocultural constructs and genomic technologies. Together, these chapters argue for methodology that is culturally sensitive, scientifically rigorous, consistent, and sustainable. And although the focus is pediatric, the book takes a lifespan approach to prevention and intervention, modeling a universal framework for understanding neurocognitive development. Included in the coverage:

Assessment of very young children in Africa in the context of HIV.Psychosocial aspects of malnutrition among African children.Assessment of neuropsychological outcomes in pediatric severe malaria.Neurodisability screening using the Ten Questions questionnaire.The neuropsychology of sickle cell disease in West African children.Computerized Cognitive Rehabilitation Therapy for African children.

As a guide to current findings or a springboard for new studies, "Neuropsychology of Children in Africa" is a necessary reference for researchers, policymakers, and diverse professionals in global aid organizations, and across the discipline.

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Perinatal hospice is a novel form of care for an unborn child who has been diagnosed with a significantly life-limiting condition. In this book, Aaron D. Cobb develops a virtue-based defense of the value of perinatal hospice. He characterizes its promotion and provision as a common project of individuals, local communities, and institutions working together to provide exemplary care. Engaging with important themes from the work of Alasdair MacIntyre and Robert Adams, he shows how perinatal hospice manifests virtues crucial to meeting the needs of families in these difficult circumstances. As a work of applied virtue ethics, this book has important normative, social, and political implications for the creation and development of structured programs of care. It grounds the view that communities ought (i) to devote resources to ensure that these programs are widely available and (ii) to develop social structures that promote awareness of and accessibility to these forms of care. A Virtue-Based Defense of Perinatal Hospice will be of interest to philosophers working in bioethics and applied virtue ethics, as well as scholars in the fields of neonatology, nursing, palliative and hospice care, and counseling who are interested in the study of perinatal hospice.

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of nonneoplastic pediatric pathology, it incorporates the most recent clinical, pathologic, and molecular knowledge in this challenging field to provide a comprehensive overview of all key issues relevant to today's practice. Richly illustrated and easy to use, Diagnostic Pathology: Nonneoplastic Pediatrics is a one-stop reference for accurate, complete pathology reports, ideal as a day-to-day reference for both pediatric and general pathologists or as a reliable training resource. Provides a clear framework for a better understanding of the clinical and histopathologic appearances of more than 270 nonneoplastic entities, covering every organ system with a focus on reactive, infectious, congenital, and genetic conditions Covers significant advances in this complex field, including recent molecular discoveries and updated disease entities, new information on multiple immunologic disorders, changes and expansions to several classification systems (such as WHO, Banff, and ISSVA), and updates in other scoring systems Contains new chapters on manifestations of pediatric COVID-19 infection, tumoral calcinosis, multiple skeletal dysplasia, skeletal muscle, collagenous gastritis and colitis, adenovirus appendicitis, intestinal pseudoobstruction, disorders of sexual development, and Kikuchi disease Includes approximately 3,000 high-quality clinical and histologic images, gross pathology images, radiologic images, and full-color illustrations to help practicing and in-training pathologists reach a confident diagnosis-as well as nearly 200 additional images online Employs consistently templated chapters and bulleted content for quick, expert reference at the point of care Includes an eBook version that enables you to access all text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud

This book examines the many ethical issues that are encountered in the Pediatric Intensive Care Unit (PICU). It supports pediatricians, nurses, residents, and other providers in their daily management of critically ill children with the dilemmas that arise. It begins by examining the evolution of pediatric critical care, and who is now impacted by this advancing medical technology. Subsequent chapters explore specific ethical concerns and controversies that are commonly encountered. These topics include how to conduct end-of-life discussions with families facing a myriad of challenging choices. It goes on to explore the concept of futility, and what that does and does not mean in the pediatric ICU setting. Controversial subjects such as children as organ donors, particularly using donation after cardiac death, in addition to issues surrounding the declaration of brain death are covered. Additional chapters address resource allocation, and also analyze the use of long-term technology in chronically critically ill children. Chapters include case examples with guidance on how to work through similar difficulties and decision-making. While this book is specifically targeted for care providers at the ICU bedside, it is also of benefit to medical students, students in bioethics, practicing ethical consultants and families who are dealing with critically ill children.

The book Gamete and Embryo-fetalOrigins of Adult Diseases introduces various diseases resulting from the abnormal gametogenesis and embryo development, which manifests as growth retardation, birth defects, or increased susceptibility to chronic metabolic diseases such as diabetes, cardiovascular disease and cancer in childhood and adult life, even fertility disorders and the risk of transgenerational transmission. Six common kinds of these diseases are discussed in separate chapters. The authors explore the connections between these diseases and epigenetic reprogramming, rapid cell differentiation and organ formation and environmental influences, including assisted reproductive technology and adverse intrauterine environments. With a summary of findings on the causes and progression of adult diseases at the phase of gametogenesis and embryo development, this book provides insights into the pathogenesis of disease and aids in the treatment and prevention of disease, meeting the requirement for improving the quality of the newborn population, and effectively preventing and curing major diseases at an early stage. This book offers new perspectives and will be an enlightening resource for obstetricians, paediatricians, epidemiologists, endocrinologists and sanitarians.

Editor He-Feng Huang, M.D., is Professor and President of Women s Hospital, School of Medicine, Zhejiang University, China. Editor Jian-Zhong Sheng, Ph.D., is Professor at the Department of Pathology & Pathophysiology, School of Medicine, Zhejiang University, China."

It is commonly accepted that "exercise is good for children" but, considering the number of children worldwide exercising, we know comparatively little, compared to adults, about how specific mechanisms influence health and sports performance. There are considerable obstacles that challenge the progress of paediatric research, not least in relation to ethical and methodological considerations. Therefore, advances in the science and clinical application of paediatric exercise physiology, psychology and biomechanics have not reached their potential. Paediatric clinical exercise physiology has application to the role of exercise in the assessment and treatment of paediatric chronic diseases, the utilization of physical activity in preventing illness and enhancing wellbeing and can enhance our understanding of how sports can be made safer and more enjoyable for our young athletes. Exercise and Respiratory Diseases in Paediatrics highlights research by various methodologies, including literature reviews, experimental research and innovations, applied to children and adolescents with respiratory diseases. Chronic conditions such as asthma, bronchiectasis (e.g., cystic fibrosis), and those associated with prematurity and medical complexity are worldwide health problems for young people and although management includes pharmaceutical medications, physiotherapy, nutritional and psychological support, exercise has a role in optimising multidisciplinary care. There has been unprecedented acceleration in new technologies and methodologies that promise to facilitate paediatric research and these are explained and discussed as future research directions. This is reading for post graduate students, researchers, academics and policy makers within the field of paediatric healthcare, physical activity, physiology and the related disciplines.

Of all children reported to child protective services for suspected maltreatment in any form, the percentage of substantiated cases of actual physical abuse is quite small. There are a number of dermatological or radiologically demonstrable musculoskeletal lesions that have been, or could be mistaken for, intentional physical abuse by the inexperienced or untrained observer.

Child Abuse and Its Mimics in Skin and Bone illustrates the classic manifestations of physical abuse by dermatological and radiological examination as a standard against which the mimickers of physical abuse can be compared. Beginning with a historical perspective on child abuse, the book explores manifestations of superficial and musculoskeletal trauma in children. It examines conditions often mistaken for child abuse, ranging from rubella to leukemia and bowing deformities to vitamin A intoxication, as well as a plethora of dermatological conditions that can mimic signs of physical abuse.

Designed for a broad spectrum of individuals who may first encounter a possibly abused child, the book presents hundreds of photos many in color and examples collected by the authors over their years of experience in their respective fields. Where appropriate, the authors provide pertinent historical, physical, and laboratory information in support of the diagnosis.

With the combined insight of top experts in forensic radiology and dermatology, this volume enables clinicians and others confronted with cases involving these conditions to avoid a rush to judgment that could wreak havoc in a family and quite possibly delay needed treatment for an actual medical condition.

In this issue of Clinics in Perinatology, guest editors Joseph B. Cantey and Andi Shane bring their considerable expertise to the topic of Perinatal and Neonatal Infections. Provides in-depth, clinical reviews on Perinatal and Neonatal Infections, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.

Human Placental Trophoblasts: Impact of Maternal Nutrition explores the vital roles of trophoblasts play in fetal growth and pregnancy, giving you new insight into the modulation of placental trophoblast functions by nutrients. It also reviews the role of fatty acids, folic acids, and specific vitamins in this aspect. The book highlights the critical role of nutrients on human placental development and its' in utero programming effects on the development of chronic diseases such as type 2 diabetes, cardiovascular diseases, hypertension, and obesity in later life. The book begins with discussions of the central process of placentation and its regulation on size and growth of the fetus. It also covers the effects of key macronutrients on placental growth, metabolism, transport, and secretory function. The text details important vitamins and few micronutrients and their roles in the feto-placental growth and development. It includes information on the influence of maternal lifestyle and environmental factors on regulation of the growth, metabolism and gene expression in the feto-placental unit. A review of the genes linked to the process of placentation rounds out the coverage. An examination of a broad range of evidence in the areas of placental growth, function, and its impact on feto-placental outcome, the book presents new knowledge on nutrition and its relevance with early human development. This includes not only the effects of maternal nutrients on possible neonatal growth and development but also their regulation by maternal lifestyle associated factors. A fine blending of epidemiology, clinical nutrition, perinatal and neonatal medicine, and biochemistry and molecular biology areas of research activities, the book helps you to understand the impact of maternal nutrition on placentation and its relevance with pregnancy outcome and fetal programming of adult health and disease.

In this issue of Clinics in Perinatology, Guest Editors Anup Katheria and Lisa Stellwagen bring their considerable expertise to the topic of Care for the Term Newborn. Top experts in the field cover key topics such as delivery room triage and transitions of care; early onset sepsis; congenital infections; postnatal screening & testing; and more. Provides in-depth, clinical reviews on Care for the Term Newborn, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews. Contains 14 relevant, practice-oriented topics including Umbilical Cord Management for vigorous and non-vigorous infants; Fetal Circulation and Critical Congenital Cardiac Disease; Alternative Birth Practices, Refusal, and Therapeutic Hesitancy; Prenatal Substance Exposure; and more.

The first 1,000 days, from conception to two years of age, is a critical period of growth and development. Exposures to dietary, environmental, hormonal, and other stressors during this window have been associated with an increased risk of poor health outcomes, some of which are irreversible. The book addresses this crucial interval of early life across biological disciplines, linking concepts related to all biological fields to outcomes during the first 1,000 days (e.g. fetal growth and pregnancy outcomes) and beyond (e.g. gut microbiome and cardiovascular disease later in life). The strength of this book lies in its cross-disciplinary nature.

This book connects experts in the field of child assessment to provide child psychiatrists with knowledge in evaluation and educational programming. The book provides a review of the latest science behind: common learning disabilities, including etiology and guidelines for assessment/diagnosis; neurodevelopmental disorders, like learning disabilities, ADHD; psychiatric disorders in childhood such as mood and anxiety disorders; and impact learning and development protocols. The Massachusetts General Hospital Guide to Learning Disabilities evaluates the interventions that are effective in addressing these learning challenges in the context of multiple factors in a way that no other current text does. Special topics such as special education law and managing the needs of transitional age youth allow psychiatrists to support their patients' and their families as they navigate the system. By offering a better understanding the learning needs of their patients, this texts gives readers the tools to consult with families and educators regarding how to address the learning needs of their patients at school and in other settings. The Massachusetts General Hospital Guide to Learning Disabilities is a vital took for child psychiatrists, students, assessment professionals, and other professionals studying or working with children suffering from learning disabilities.

Nutrients play a significant role in brain development throughout fetal and postnatal life. This book reviews the evidence from animal and human research, highlighting the influence of specific nutrients on brain function and cognitive development. With a unique, integrative approach to the nutritional, environmental, and genetic influences on brain development, the book examines issues such as single versus multiple limiting nutrients, critical periods of deficiency, and the impact of the child-parent relationship on the architecture of the developing brain. The effect of undernutrition on the developing brain of infants and young children can be devastating and enduring. It can impede behavioural and cognitive development and educability, thereby undermining future work productivity. Chapter authors are experts in this field of research and provide an up-to-date insight into the role of the individual nutrients in brain development and function.

Many factors affect treatment options for children and adolescents with mental health problems, including age, severity of symptoms, financial and time constraints, and access to qualified professionals. With the limitations of managed care plans and the shrinking pool of pediatric psychiatrists, the trend is toward pediatricians prescribing psychotropic medicines. Pharmacologically trained psychologists can offer valuable assistance to pediatricians caught in this predicament. Tackling fundamental questions of when to treat as well as when and why to refer young patients, Pediatricians and Pharmacologically Trained Psychologists examines commonly occurring pediatric conditions requiring joint treatment; reviews theoretical models of consultation and collaboration; and spotlights professional issues typically arising from these team efforts. With pertinent clarity and detail, this volume offers in-depth discussion in these key areas: * Collaborative treatment of mental health conditions, including mood, disruptive, anxiety, and eating disorders. * Collaborative treatment of medical conditions, focusing on gastrointestinal disorders and diabetes. * Changing clinical procedures in states that have enacted prescriptive authority for psychologists. * Expanding roles for pharmacologically trained psychologists practicing in states that have not enacted prescriptive authority for psychologists. * Medical psychology in the pediatric hospital. * Integrative care in rural settings and on the reservation. * The collaborative future: brain marker technology, training paradigms, and more. Pediatricians and Pharmacologically Trained Psychologists is a must-have reference for a broad range of researchers, professionals, and graduate students, including psychologists, pediatricians and other child mental health clinicians as well as nonphysician prescribers, such as nurses, physician assistants, and pharmacists.

Handbook of Adolescent Medicine and Health Promotion is a medical handbook for health providers, residents, and students as well as other interdisciplinary practitioners who promote the health and well-being of adolescents and young adults. With an emphasis on practical clinical approaches covering comprehensive health evaluation, which impacts on health choices and behaviors, health screening, education and health promotion, this book is a unique combination of pediatrics, internal medicine, gynecology, and psychology. The behavioral and health promotion aspects for adolescents are discussed in depth, with elaboration on the real difference between adolescent medicine and other specialties. An excellent reference, it provides useful case materials and handouts in an easy-to-read format. This book is an absolute must-have for improving the health outcomes and well-being of adolescents and young adults.

The Parent's Guide to Eating Disorders shows that effective solutions begin at home and cost little more than a healthy investment of time, effort, and love. Based on exciting new research, it differs from similar books in several key ways. Instead of concentrating on the grim, expensive hospital stays of patients with severe disorders, the authors focus on the family, teaching parents how to examine and understand their family’s approach to food and body-image issues and its effect their child’s behavior. Parents learn to identify an eating disorder early, to establish healthy attitudes toward food at a young age, and to intervene in a nonthreatening, nonjudgmental way. The authors concentrate on teens, the age group most often affected by eating disorders, as well as younger children. Individual chapters cover boys at risk, relapse training, dealing with friends, school, and summer camp, and much more. The book includes an appendix and sections on further reading, organizations and websites, residential and hospital programs, and references.