In rowing, races are often won in spite of, not because of, technique, and many misconceptions still preoccupy both rowers and coaches. This book explains the facts about rowing technique and will help you to find the right way to achieve your best performance. In this new edition, comprehensively updated to take account of the most recent developments in the sport The Biomechanics of Rowing offers a unique insight into the technical and tactical aspects of rowing, based on over twenty-five years experience of working with the best rowers and coaches all around the globe, a careful analysis of millions of data samples, and comprehensive biomechanical modelling with the aim of finding an optimal balance of variables. Topics covered include measurement; performance analysis; technique; ergometer rowing and, finally, rowing equipment and rigging.

This manual provides laboratory-based learning experiences in perceptually and psychosocially linked exercise assessment, prescription, and programming. The primary pedagogic outcome is the ability to use applied theory and practice in perceptual and psychosocial exercise assessment and program design to promote the adoption and maintenance of a physically active lifestyle, enhancing overall health fitness. Perceptual and psychosocial variables are presented in individual, stand-alone laboratory modules that can supplement existing curricula such as exercise and sport psychology, exercise physiology, exercise testing and prescription, and exercise training and conditioning. In addition, the complete modular set has a conceptual flow that allows its presentation as an entire, laboratory-based course. The laboratory modules are divided into three primary units: assessment (theoretical constructs, scales and procedures, tests), prescription (self-regulation, performance), and program evaluation. The manual uses a unique format in which case studies are embedded in the conceptual flow of each lab module facilitating translation of laboratory results to real-world application. The manual concludes with a discussion of perceptually and psychosocially linked exercise prescription and programming applications in public health, such as program monitoring and adherence.

Genetics, Neurology, Behavior, and Diet in Dementia: The Neuroscience of Dementia, Volume 2 consolidates different fields of dementia research into a single book, covering a range of subjects, including Alzheimer's disease, Lewy body dementia, mixed dementia, vascular dementia, physical activity, risk factors, mortality, biomarkers, SPECT, CT, MRI, questionnaires, nutrition, sleep, delirium, hearing loss, agitation, aggression, delusions, anxiety, depression, hallucinations, psychosis, senile plaques, tau and amyloid-beta, neuroinflammation, and molecular biology. This foundational, comprehensive book assembles the latest understanding on all dementias and their common features in a single source. It is an invaluable resource for neuroscientists, neurologists, and anyone in the field.

The biopharmaceutical industry has become an increasingly important player in the global economy, and the success of these products depends on the development and implementation of cost-effective, robust and scaleable production processes. Bioseparations-also called downstream processing- can be a key source of competitive advantageto biopharmaceutical developers. Process Scale Bioseparations for the Biopharmaceutical Industry brings together scientific principles, empirical approaches, and practical considerations for designing industrial downstream bioprocesses for various classes of biomolecules.
Using clear language along with numerous case studies, examples, tables, flow charts, and schematics, the book presents perspectives from experienced professionals involved in purification processes and industrial downstream unit operations. The authors provide useful experimental design strategies and guidelines for developing application-specific process scale bioseparations. Chapter topics include harvest by centrifugation and filtration, expanded bed chromatography, protein refolding, modes of preparative chromatography, methodologies for resin screening, membrane chromatography, protein crystallization, viral filtration, ultrafiltration/diafiltration, implementing post-approval downstream process changes for an antibody product, and future trends.
Ideal for both new and experienced scientists in the biopharmaceutical industry and students, Process Scale Bioseparations for the Biopharmaceutical Industry is a comprehensive resource for all topics relevant to industrial process development.

Historically, most of the research into carbohydrates as functional ingredients focused on the improvement of appearance, taste, mouth-feel, and stability. The growing interest in functional foods, however, is demanding a critical look at the beneficial nonnutritive effects of carbohydrates on human health. Furthermore, there is a need to establish definitive relations among the structure, physical property, and physiological function of these bioactive compounds. As more of the benefit and functional versatility of carbohydrates is revealed, it is clear that any future research and recommendation must be based on a solid synthesis of multidisciplinary findings including epidemiological, metabolic, and clinical nutritional data.

Through clinical and epidemiological studies, Functional Food Carbohydrates addresses the specific classes of carbohydrates that seem to exert health-enhancing effects. The text begins with in-depth treatments of the chemistry, physical properties, processing technology, safety and health benefits of a variety of carbohydrates including cereal beta-glucans, microbial polysaccharides, chitosan, arabinoxylans, resistant starch, and other polysaccharides of plant origin. The authors then discuss the physiological and metabolic effects that a variety of carbohydrates have on specific chronic diseases such as cancer, diabetes, cardiovascular disease, obesity, and various gastrointestinal disorders. The final chapters discuss the regulatory and technological aspects of using carbohydrates as functional foods. Specifically, the authors consider the safety and efficacy of pre-, pro-, and synbiotics, and the potential use of carbohydrates as delivery vehicles forother bioactive compounds.

With contributions from experts specializing in food chemistry and technology, as well as human nutrition and physiology, this text illuminates the link between the behavior of carbohydrate compounds and their beneficial end-result on human health.

The book is designed as an introduction to the scientific study of speech. No prior knowledge of phonetics is assumed. As far as mathematical knowlege is concerned, all that is assumed is a knowledge of simple arithmetic and as far as possible concepts are dealt with on an intuitive rather than mathematical level. The anatomical material is all fully explained and illustrated. The book is arranged in four parts. Part 1, Basic Principles, provides an introduction to established phonetic theory and to the principles of phonetic analysis and description, including phonetic transcription. Part 2, Acoustic Phonetics, considers the physical nature of speech sounds as they pass through the air between speaker and hearer. It includes sections on temporal measurement, fundamental frequency, spectra and spectrograms. Part 3, Auditory Phonetics, covers the anatomy of the ear and the perception of loudness, pitch and quality. The final part, Part 4, covers the articulatory production of speech, and shows how experimentaltechniques and tools can enhance our understanding of the complexities of speech production.
Though the audience for this book is mainly students and professors in the Speech Sciences, it will also be valuable to any students studying hearing science and acoustics. The book is well supported with figures, tables, and practice boxes with experiments.

This is the loose-leaf version of Biomechanics of Sport and Exercise, Fourth Edition With Web Resource, which offers students a lower-price printed version of the text. Other binding options are also available. A standout among introductory biomechanics texts, Biomechanics of Sport and Exercise, Fourth Edition With Web Resource, takes a unique approach to introducing exercise and sport biomechanics. Using simple terms, the book presents mechanics before functional anatomy, helping students first understand external forces and their effects on motion; then explores how the musculoskeletal system responds and generates its own internal forces to maintain position; and finally shows how to apply biomechanical principles to analyze movement and ultimately improve performance. The fourth edition expands its commitment to enabling students to discover the principles of biomechanics through observation. Easy-to-understand experiments are presented for students to try in the classroom or on their own. Sample problem sidebars guide students through choosing the appropriate equation to determine the forces acting or motion occurring in a specific scenario and then helps them solve the equation. This practical approach-combining clear illustrations, sample calculations, and encouragement for active learning-helps students develop a deeper understanding of the underlying mechanical concepts. In addition to careful updates throughout the book, other new enhancements in the fourth edition include the following: New content explores the technologies and devices available to coaches, athletes, and the general public to measure aspects of athletes' movements. New full-color art and diagrams enhance the text and help students visualize mechanics in real-world scenarios. Explanations of the equations used in the text make the content more accessible to students. New concept application boxes provide deeper analysis of the field use of biomechanics, with topics such as the Magnus effect in baseball pitching, the wetsuit effect in triathlons, power output in cycling, centripetal acceleration when running a curve, and the work-energy principles in modern shot putting. Other learning aids include bold key terms, chapter objectives, and a guide to key equations and abbreviations. The chapters include a total of 18 sample problems that students can solve using a step-by-step process. A companion web resource offers additional review questions and problem sets. Biomechanics of Sport and Exercise, Fourth Edition, introduces the biomechanics of human movement in a clear and concise manner while promoting an active, engaged learning experience. Students will discover the principles of mechanics for themselves, resulting in a strong understanding of the subject matter.

Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.

This book explains the anatomy function of different parts of the body and examines the types of movement important in sports activities. This book gives a detailed analysis of movement, general characteristics of bones, joints, and muscles, as well as guidelines for flexibility and strength training. It emphasizes important factors for maximizing performance and is a bridge between biomechanics and the practice of sport. The book's unique approach features a rigorous application of biomechanics to sport training. Mechanics are related to the use of muscles in specific sports. Coverage is both theoretical and practical, making the book useful both for academic study and as a training aid. Highly illustrated format helps readers understand key concepts and important details. Fully updated content provides the latest knowledge on the subject. New illustrations and new, engaging text layout draw the reader in and bring important concepts to life. Additional coverage has been added on several topics, including strength training.

This is an edited collection of peer-reviewed papers presented at the Ninth International Conference of the Society for the Advancement of Kinanthropometry. Defined as the relationship between human body structure and function, kinanthropometry is an area of growing interest, and these proceedings will be of use to students, academics and professionals in the areas of ergonomics, sports science, nutrition, health, and other allied fields. The assembled works represent the latest research findings across kinanthropometry, moving the discipline forward and promoting good practice and the exchange of expertise.

The advances made in vascular biology in the last 25 years have considerably changed the perception that one could have of the endothelial cells. Once considered as a diffusion barrier preventing the access of the blood cells to the vascular matrix, the endothelium is now recognized as playing a major role in the control of blood fluidity, platelet aggregation, and vascular tone, but also in immunology, inflammation, angiogenesis, and for serving as a metabolizing and an endocrine organ.
-- from the preface
Cardiovascular diseases, so prevalent in the Western world during the twentieth century, could well become the scourge of the twenty-first century in emerging countries as well as the West. Endothelial dysfunction linked to an imbalance in the synthesis and/or release of contracting and relaxing factors is often evoked to explain the initiation of the cardiovascular pathology or its development and perpetuation. Two decades ago, when nitric oxide was demonstrated to mediate endothelium-dependent relaxations, the vascular world seemed convinced that nitric oxide was the ultimate and sole explanation for such relaxations. However not everyone agreed.
EDHF: The Complete Story is the work of two leading researchers who did not accept that simple conclusion, but instead continued to search, along with others, for a deeper understanding of the ways in which endothelial cells communicate with the underlying smooth muscle to signal it to hyperpolarize. Now with most, if not all, of those ways, uncovered, the authors offer this summary as way of bringing closure to the quest.
This monograph reports on the work of many researchers. It summarizes the significant recent discoveries concerning endothelium-dependent hyperpolarizations, which are likely to play a much more important role in cardiovascular physiology and pathology than was originally foreseen
Extensively illustrated with original diagrams and schematics that summarize the different steps of endothelium-dependent hyperpolarization, the text is designed for vascular biologists, and cardiologists, as well as graduate students looking to gain an understanding of the intimate functioning of the blood vessel wall.

That a relation exists between lipids/lipoproteins and coronary artery disease is no longer an arguable point. However, the complexities associated with this relationship, and the number of factors that can impact and alter circumstances and clinical status, are many and diverse. Consequently, this relationship continues to receive a great deal of focus from researchers. Lipid Metabolism and Health, in presenting the latest statement from those positioned on the cutting edge in this arena, provides an overview and historical perspective of the evolution of serum lipids and lipoproteins. It traces their development from a mere curiosity to their acceptance as an established and major coronary artery disease (CAD) risk factor, and, ultimately, to their becoming the subject of clinical guidelines. Considerable attention is focused on the fundamentals, beginning with a chapter on basic lipidology, and progresses through such topics as lipid/lipoprotein metabolism, and the biology of atherosclerosis. Additional topics include methodologies for measuring lipoproteins, clinical strategies used to manage unhealthy lipid levels, and discussion of important influential factors such as obesity, diabetes and metabolic syndrome, diet/nutrition, exercise, cigarette smoking and environmental tobacco smoke, and age, as well as gender, race, and other heredity factors. Qualified and recognized experts in their specific fields of study were recruited by the editors to contribute chapters. They include top researchers in, nutrition, pharmacology, exercise science, and several areas of clinical medicine including cardiology, kinesiology, and immunology. Lipid Metabolism and Health provides a usefulscientific and educational tool for researchers, clinicians, academicians, and students seeking a timely and bona fide source of information on the relationship between lipids and health.

This book is a synopsis of the key facts and concepts of human development. It is intended for students who are taking a human embryology course. The book includes the underlying mechanisms involved in clinically important congenital anomalies that will prove useful to medical and nursing.

Surgery continues to be the most effective treatment of solid tumors in terms of recovery, while its combination with other treatments improves the survival curves especially in the advanced forms of the disease. The aim of my task first of all has been to provide readers with both the current and constantly evolving pathophysiologic knowledge required for building the foundation of a specific education enabling surgeons to meet the fundamental targets in surgical oncology. Secondly, this volume aims to present an update on the real possibilities offered by the cooperation between surgeon and pathologist and by chemotherapy, radiotherapy and gene therapy in the treatment of tumors in the light of the most recent scientific achievements. Lastly, the report presents the experiences and cases drawn mostly from our School regarding some of the major issues in oncologic surgery. This overview does not pretend to elucidate or to summarize all aspects of oncologic surgery, but rather to be the result of a general consideration on cancer surgery, on its rational bases, on its interaction with other treatment modalities, on its desirable and expected developments and on its probable future evolution.

With chapters by many of the foremost international authorities on aging, neurology, physical therapy, and rehabilitation, this reference provides an up-to-date review of approaches to gait disorders and falls. This volume presents the fundamental concepts of gait and describes the changes in mobility with aging and disease. A focus is placed on recent assessment and intervention practices for common gait disorders, especially those seen in older adults, including sections on neuro-psychological influences, fear of falling and exercise, and strategies for specific disease groups, such as patients with neurological disorders or those recovering from stroke or hip surgery.

Investigations involving incisive mechanistic dissection of various types of synaptic plasticity have revealed that it plays key roles in neural development, sensory information processing, cortical remapping following brain injury, perception, and behavioral learning and memory. Disruptions of synaptic plasticity may underlie neurological and behavioral disorders such as Alzheimer disease, Fragile-X syndrome, autism, and drug addiction. Multidisciplinary Tools for Investigating Synaptic Plasticity, therefore, assembles expert contributions that highlight techniques and strategies used in probing the cellular and molecular mechanisms of synaptic plasticity in the nervous systems of vertebrate and invertebrate species. Divided into three sections, this meticulous volume describes biochemical and genetic strategies for studying synaptic plasticity, behavior, neural development, and synaptogenesis, and also includes cellular electrophysiological and optical methods for interrogating a diverse array of mechanistic issues. As part of the Neuromethods series, this book contains the kind of detail and key implementation advice that maximizes successful results. Authoritative and invaluable, Multidisciplinary Tools for Investigating Synaptic Plasticity serves as an ideal primer for introducing researchers to specific techniques that will enhance their success at addressing novel questions in synaptic plasticity at the lab bench.

For one-semester courses in anatomy & physiology. Celebrated for its precise illustrations, emphasis on integration, and engaging clinical content, Essentials of Anatomy & Physiology is crafted especially for students with no prior knowledge of anatomy & physiology and little science background. The 8th Edition guides students through tough A&P topics, helping them retain challenging content in the fast-paced one-semester A&P course. The new edition draws on the outstanding art and hallmark features from the text to create interactives and digital assets that walk students through complicated art and help them to understand difficult concepts. NEW Build Your Knowledge Interactives focus on how the body systems work together to maintain homeostasis.

Anatomy and physiology presented in a clear and accessible manner for the midwifery student. Well illustrated with numerous line diagrams, Anatomy & Physiology in Maternity Care takes a system-approach to the physiological changes that occur throughout the childbearing year. Varied case studies reflecting the latest research findings ensure that theory is firmly rooted in midwifery practice. This is an excellent first textbook for those students needing to understand the anatomy and physiology of pregnancy and childbirth An introductory text covering anatomy and physiology relevant to midwifery students Simple, accessible language ensures complete understanding of complex theory Case studies relate anatomy and physiology to midwifery practice Covers physiological changes throughout the childbearing year Updated references New case studies reflecting latest research findings

Packed with vivid illustrations and a wealth of hands-on applications, best-selling FUNDAMENTALS OF ANATOMY AND PHYSIOLOGY, 4E is written specifically for learners in a one-semester introductory A&P course in the allied health field who have little or no previous knowledge of anatomy and physiology. Known for its clear approach to teaching, the text is widely praised for its ability to break A&P down into very simple, easy to understand language. Content is organized according to body systems, and focuses on the body working together to promote homeostasis. Improving both the quality and quantity of text illustrations, the Fourth Edition's new art program brings text concepts to life with new figures throughout. Designed specifically for the needs of health care programs, the all-new Learning Lab's interactive simulation program helps learners maximize their success.

No matter when you make changes in your life, you can still reap the benefits of bolstering your gut, reinvigorating its digestive and immune capabilities, and boosting your overall health.

Brain Hypoxia and Ischemia explores the various aspects of cell death and survival that are crucial for understanding the basic mechanisms underlying brain hypoxia and ischemia. Chapters focus on a panorama of issues including the role of ion channels/transporters, mitochondria and apoptotic mechanisms, the roles of glutamate/NMDA, mechanisms in penumbral cells and the importance of intermittent hypoxia and gene regulation under these stressful conditions. The volume explores findings from both mammalian and invertebrate model systems and their applicability to human systems and diseases. Careful consideration is also given to differences in hypoxia and ischemia across development.

This volume aims to increase the understanding of these mechanisms and to stimulate research on better diagnosis and treatment of diseases that afflict the brain and potentially other organs when O2 levels are dysregulated. Brain Hypoxia and Ischemia is designed for neuroscientists, clinicians and medical/graduate students for use in both basic research and clinical practice.

Instant Notes in Sport and Exercise Physiology looks at the key topics in exercise physiology and examines how each of the physiological systems responds to acute and chronic exercise. As well as reviewing special topics such as nutrition, altitude, temperature, and ergogenic acids, it assesses the importance of exercise to health and quality of life and considers the importance of exercise to adults, children and the elderly.

Contents:
1. The Role of Drug Metabolism and Pharmacokinetics in Drug Discovery: Past, Present and Future 2. The Importance of the Physiochemical Properties of Drugs to Drug Metabolism 3. Sample Preparation 4. High Performance Liquid Chromatography in Pharmaceutical Bioanalysis 5. Quantitative Mass Spectronomy 6. Immunoassay in Bioanalysis 7. Phase I Metabolism 8. Phase II Enzymes 9. In vitro Techniques for Investigating Metabolism 10. Drug to Drug Interactions: an in vitro Approach 11. Clinical Impact of Drug Interactions 12. PreClinical Pharmacokinetics 13. Pharmacokinetic / Pharmacodynamic Modelling in PreClinical Drug Discovery 14. Toxicokinetics 15. Protein Binding in PlasmaA Case History of a Highly Protein Bound Drug 16. Metabolite Identification by Spectroscopy 17. Whole Body Autoradiography 18. Radiolabelled Studies in Man 19. Molecular Biology

Muscle strength is an important topic for ergonomics practitioners and physiologists to understand, especially as it relates to workplace injuries. Muscle strength and function is at the heart of many injuries that lead to reduced productivity and economic strain on the worker, the company, and society as a whole.
This comprehensive source of information and data relating to muscle strength is the first to present such information in a single source. Muscle Strength explains the general determinants of muscle strength such as gender, age, and muscle type. It illustrates physical data in the context of theoretical background and examines the protocols, techniques, devices, and data used to record muscle strength in various parts of the body. This is followed by a discussion of overexertion, strength prediction, strength and endurance, torque and EMG relationship, and muscle fatigue. Finally, the material is applied to the use of muscle in jobs, to product design, and to studies of job accommodation and the effect of disability on strength.
Professionals in ergonomics, biomechanics, sports science, and physiology will find that this unique text provides insight and data on an important subject in their field.