This comprehensive overview of the known literature concerning the physical and psychosocial health of children conceived by ART brings together an international panel of experts in fertility medicine, epidemiology, medical genetics, obstetrics, twin research, psychosocial development and pediatrics. Each chapter gives a concise, readable commentary on the key areas of established knowledge. The book will prove an essential component for clinic library for fertility practitioners throughout the world. It will be useful for counselling families about known risks, and for placing in context what is generally a positive literature. Knowledge in this area has been restricted by the studies performed; however, there is a body of research that is hard for the busy fertility practitioner, counsellor, fertility nurse, or obstetrician to bring together and synthesize for their clients. The book is edited by Dr Alastair Sutcliffe - one of the world experts in this field. This is a revised and expanded edition of IVF Children - The First Generation. It is hoped that this will be a continuing project, in which periodic further updates will be published to maintain the currency of quality information needed to inform practitioners of what is a rapidly changing field.

Give yourself the best-possible odds for getting pregnant and having a baby with this concise, expert, and encouraging companion as your guide. In the only general guide to infertility written by a medical doctor who specializes in the subject, Mark Trolice, MD—who is board-certified in both OB/GYN and REI (Reproductive Endocrinology and Infertility)—shares the practical knowledge he has gained from working in infertility medicine for years, with many hundreds of patients, along with the warmth and wisdom he has acquired from getting to know prospective parents from all kind of backgrounds. The journey from infertility to fertility, from childlessness to a brand-new baby, can be long and arduous. It involves complicated medical diagnoses, a wide range of treatment options, a host of potential lifestyle changes, lots of emotional ups and downs, and—even with the best medical insurance—challenging financial decisions. Your doctors cannot decide everything for you, and that is why an authoritative and comprehensive book, written in clear and understandable language for the layperson, is essential. This is that book. The book opens with an exploration of all the possible causes of infertility, covering both couples who have never been pregnant and ones who have had recurrent losses of pregnancies. Unique among infertility guides, this volume gives roughly equal weight to male and female causes, which is important because about 40% of infertility cases are due to men's issues—and some couples need to address issues in both the prospective mother and prospective father. It covers endometriosis, fibroids, POS (Polycystic Ovarian Syndrome), tubal factor, male factor, and other possible causes. Next it looks at your treatment options. Importantly, these are not just medical interventions, but they also include lifestyle changes you alone can make, involving sleep, diet, exercise, and other forms of self-care. Among medical options, IUI (Intrauterine Insemination),  IVF (In Vitro Fertilization), and various surgical procedures are covered in detail. Some couples are lucky to have a short journey to fertility. For others, the process takes years. With a gentle and sure hand, and non-judgmentally, Dr. Trolice guides you through the many decisions you need to make along the way, such as whether or not to continue treatments, whether to change practitioners or treatments, and whether it is a good idea to continue to spend money on procedures not covered by your insurance. He understands that these are emotionally weighty decisions that involve the future of your family, and he provides ample grounds for optimism and hope, empowering you as you take this journey.

Written by two urologists and a genitourinary physician, this impeccably researched text provides the reader with a comprehensive overview of sexual health, exploring a range of topics such as: sexually transmitted infections; contraception; urological conditions; genital dermatoses; sexual dysfunction; novel therapeutic options. With a clear, symptom-based format, this is an ideal quick reference guide for the consulting room and the ward.

What is it about the challenges and stresses of midlife that disrupts equilibrium and promotes a sense of despair, even of crisis? Why does this stage of the life cycle give rise to new mental and physical symptoms that, for some, lead to chronic unhappiness to the point of dysfunction? Of course, there are common midlife events that account for the special narcissistic vulnerabilities of this period of life, and Eda Goldstein ably reviews these events and the theoretical perspectives commonly brought to bear on them. In When the Bubble Bursts, however, Goldstein's special concern is those individuals who come to midlife with heightened narcissistic vulnerabilities that make the navigation of this stage of life more difficult still. In understanding the latter such patients and devising a treatment approach appropriate to their self issues, Goldstein adopts a broadly self-psychological frame of reference. It is a matter, she finds again and again, of understanding how current stressors frustrate healthy self needs and trigger narcissistic vulnerabilities. purview, embraces modalities that are, to varying degrees, supportive, psychodynamic, and psychoanalytic, reworks and strengthens self structures in helping patients find new ways of affirming their sense of self. Her substantive case studies, which accompany the reader through all the chapters in her study, draw on personal and supervisory experiences to illustrate crucial foci of the treatment process with a range of midlife patients in psychotherapy. It is a striking that, amid a voluminous literature on psychodynamic psychotherapy, so little attention has been paid to the narcissistic vulnerabilities of midlife and the manner in which they enter into the psychotherapy of midlife patients. Eda Goldstein remedies this glaring lacuna in the literature with a study that comprises an admirable blend of theoretical astuteness, clinical wisdom, and personal honesty. balanced discussion of theoretical perspectives on adult development and her concluding consideration of the countertransference issues elicited by midlife patient in their midlife therapists, is an edifying and ingratiating contribution to the literatures of psychodynamic psychotherapy, self psychology, and adult development.

Offering an authoritative collection of chapters from clinicians and researchers in the United States, Canada, and Europe, this reference comprehensively covers the latest understanding in the etiology, pathophysiology, diagnosis, and treatment of sexual dysfunction.

Wedding up-to-date scientific information to an understanding of the emotional burdens and ethical dilemmas that inhere in reproductive medicine, Frozen Dreams: Psychodynamic Dimensions of Infertility and Assisted Reproduction provides an overview of the psychology of infertility patients and of the evaluative, administrative, and especially psychotherapeutic issues involved in helping them. The contributors to this volume, who include professionals from nationally prestigious reproductive programs and psychotherapists who evaluate and work clinically with infertility patients, explore the complex choices about life and death that are the daily experience of infertility specialists. In voices equally authoritative and intimate, psychotherapists and other health professionals explore the therapeutic process with patients and couples struggling with miscarriage, infertility, childlessness, the possibility of adoption, and the promise of assisted pregnancy. Among the themes that recur throughout this collection are the following: When is a patient's bitterness, anger, and psychopathology extreme enough to disqualify her as a candidate for infertility treatment? the well-being of offspring resulting from an assisted pregnancy? How does the clinician's personal diagnosis of infertility influence an ongoing psychodynamic treatment? How can a therapist help patients overcome the overwhelming grief of miscarriage? And the contributors are equally attentive to the range of issues that challenge physicians and nurses active in reproductive medicine. Intent on providing practical information that will aid decision-making in this demanding area of practice, they examine questions such as: How reproductive medicine programs should handle difficult patients who present with a sense of entitlement. How staff differences within reproductive medicine programs can be constructively addressed and resolved. Why physicians, nurses, and other program personnel experience burnout and what can be done to prevent it. Written for a large audience of psychiatrists, psychologists, social workers, researchers, nurses, physicians, and general readers, Frozen Dreams is a fascinating introduction to the human face of reproductive medicine. mental health professionals who work with adult patients through their childbearing years. For professionals who work inside the complex world of infertility treatment, Frozen Dreams will quickly become an essential text that is turned to repeatedly for information, guidance, reassurance, and revitalization.

APPRAISAL AND REVALIDATION SERIES The new Appraisal and Revalidation Series helps doctors demonstrate their competence to the standard expected by the General Medical Council and to the standard expected if they are recognised as having 'special clinical interests'. It helps doctors gather evidence of their performance for appraisal and revalidation portfolios. This fifth book in the series examines the practical ways to identify learning and service needs within the areas of substance abuse palliative care musculoskeletal conditions and prescribing practice. It also provides guidance on how to collect data to demonstrate learning competence performance and service delivery standards. All general practitioners and those with special clinical interests and primary care organisation leads will find this book essential reading. For more information on other titles in this series please click here

Preimplantation genetic testing (PGT) is now well established as a valuable treatment option for patients wishing to start or continue a family, for a range of indications from advanced maternal age to high risk of transmitting inherited disease. This text brings together contemporary thinking from international opinion leaders and will be an invaluable guide for practitioners in Reproductive Medicine wishing to keep pace with the latest developments and clinical data.

This book examines the United States as a destination for international consumers of assisted fertility services, including egg donation, surrogacy, and sex selection. Based on interviews conducted with fertility industry insiders who market their services to an international clientele in three of the largest American hubs of the global fertility marketplace - New York City, Los Angeles, and San Francisco - and focusing on the providers rather than the consumers of assisted fertility services, the book shines a light on how professional ethics and norms, in addition to personal moralities, shape the practice of reproductive tourism.

In the late 1990s, Egypt experienced a boom period in in vitro fertilization (IVF) technology and now boasts more IVF clinics than neighboring Israel. In this book, Marcia Inhorn writes of her fieldwork among affluent, elite couples who sought in vitro fertilization in Egypt, a country which is not only at the forefront of IVF technology in the Middle East, but also a center of Islamic education in the region. Inhorn examines the scientific, religious and cultural ramifications of the transfer of IVF technology from Euro-American points of origin to Egypt - showing how cultural ideas reshape the use of this technology and in turn, how the technology is reshaping cultural ideas in Egypt.

The continued debate regarding the stage at which the human embryo conceived in the laboratory should be placed in the mother, combined with recent developments in culture media formulations, have brought the role of the human blastocyst in ART back into the spotlight. ART and the Human Blastocyst presents the proceedings of the International Symposium on ART and the Human Blastocyst held from March 30- April 2, 2000 in Dana Point, California. This book brings to the forefront the main issues raised with the transfer of embryos at the blastocyst stage, including the reduction of high order multiple gestations and the role of the blastocyst culture and transfer in facilitating successful single embryo transfer. Sections include gamete quality and pregnancy outcome, physiology of the embryo, blastocyst development in culture, blastocyst transfer and fate, and implantation. More than 40 illustrations and 25 tables complement the text.

"I say that this is a dirty, filthy book, and the test of it is that no human being would allow that book on his table, no decently educated English husband would allow even his wife to have it...." Such was the uncompromising pronouncement of Sir Hardinge Gifford, Her Majesty's Solicitor General, who in 1877 prosecuted Charles Bradlaugh and Annie Besant for publishing Dr. Charles Knowlton's Fruits of Philosophy.

Knowlton's work was the first American medical handbook on contraception. It had become an incredibly popular book among Britons who believed the neo-Malthusian dictum that the only solution to poverty in Britain was a limit on the growth of its population. They saw effective birth control measures as a way to make such a limit practicable. In 1877, its publisher was hauled into court and pleaded guilty to printing obscene material. Bradlaugh and Besant tested the right of official harassment by bringing out an edition of the Fruits of Philosophy that bore an introduction explaining their motives. The pair was arrested and charged with violating the Obscene Publications Act of 1857.

Their arrest, trial, conviction, and eventual acquittal constitute a landmark in the history of the world birth control movement. The enormous publicity accorded the principals and their cause brought the subject of family planning into the homes of nearly every Briton who read the newspapers' sensational coverage. What followed thereafter is telling: a dramatic, steady decline in the English birthrate. By their simple act of publishing Knowlton's short book, Bradlaugh and Besant helped establish England's pioneering role in the dissemination, democratization, and implementation of birth controlinformation.

This volume contains the writings of Charles Knowlton and Annie Besant on reproductive physiology and birth control and an account of the Bradlaugh-Besant trial. Included also are two of Besant's own pamphlets on birth control, and a comprehensive introductory essay that establishes a context for understanding neo-Malthusianism and the advocacy of birth control in nineteenth-century England. One of a small handful of books that helped stimulate a women's movement in the West, it will interest sociologists and gender studies specialists as well as the general reader interested in the history of birth control.

This book is a synopsis of the key facts and concepts of human development. It is intended for students who are taking a human embryology course. The book includes the underlying mechanisms involved in clinically important congenital anomalies that will prove useful to medical and nursing.

The potential impact of work being conducted in genomics, proteomics, and metabolomics upon clinical practice for gynecologists is immense but not yet completely appreciated. This groundbreaking text from international experts examines the newest topics on the perinatal agenda and gives clinicians a real look into the future via the newest methodologies.

This book stems from the author's clinical experience working with infertile women in psychotherapy and psychoanalysis. It highlights the crucial importance of integrative work of psychotherapists and psychoanalysts with reproductive medical specialists in assisted reproductive technology (ART).

A new model for treating infertility

This new book offers a revolutionary clinical model for treating individuals and couples who are infertile. The authors reveal how infertility profoundly affects a sense of identity and colors the most intimate relationships with family and friAnds. Step by step, this vital resource, shows clinicians how they can learn to support clients in overcoming their inevitable sense of loss and help them to regain their power.

The authors' advocacy of acceptance of infertility is a liberating approach for families who have been struggling to `resolve' these life long issues. This original book . . . .Can change your life.

--Linda Perilstein, executive director, Cradle of Hope Adoption Center, Washington, DC

Fertility preservation has become one of the most important and fast growing fields of reproductive medicine. Although there are several strategies for fertility preservation in female, most of them are still considered experimental. It is important to perfect the existing technologies, but also developing new strategies should be actively sought. The future development of fertility preservation strategies should be based on the sound scientific knowledge and principles. One of the main objectives of fertility preservation in females is prevention of oocyte depletion. The mechanisms of oocyte loss and survival in the ovary are complex, which include genetic control both in germ cells and in somatic cells, DNA damage and repair mechanism, apoptosis and autophagy, and other poorly understood molecular mechanisms. To develop clinically effective and safe strategies for fertility preservation, it is essential to know and understand the fundamentals of oocyte and ovarian biology at the molecular level. Thus, the purpose of this edition is to review the current progress in research related to molecular and genetic control of oocyte development that can be applied to fertility preservation. The main topics that are discussed in this publication include molecular signaling mechanisms of oocyte activation and loss, genomic integrity of oocytes, and epigenetics. "

Written by the authors of the renowned embryology textbooks The Developing Human and Before We Are Born, Concise Clinical Embryology: An Integrated, Case-Based Approach offers essential, high-yield information and high-quality clinical cases to illustrate key principles of embryology and their relevance to everyday practice. Ideally tailored to the needs of today's medical students and medical courses, this concise text clearly explains how embryology relates to other medical disciplines and its importance in safe, effective clinical practice. Abundant illustrations throughout help you grasp highly visual concepts quickly and easily. Provides easily digestible, clinically oriented coverage of human development, establishing key principles in a week-by-week, stage-by-stage approach, before moving on to fetal organ development by body system. Includes clinical cases and follow-up questions in each chapter that help relate key principles to everyday practice, aid in problem-based learning, and offer review for exam preparation. Covers the latest advances in embryology, including normal and abnormal embryogenesis, causes of birth defects, and the role of genes in human development. Contains superb illustrations from cover to cover, including diagnostic images, full color figures, histology, and more. Summarizes molecular biology highlights throughout the text. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access 18 3D animations with expert commentary, plus all of the text, figures, and references from the book on a variety of devices.

An analysis of cell death in reproductive physiology. It examines topics such as the control of apoptosis in the uterus during decidualization and stern cell factor regulation of apoptosis in mouse primordial germ cells.

This new edition is a complete guide to infertility management for specialists in reproductive medicine and trainees. Divided into 28 chapters, the book begins with an overview of the prevalence of infertility, female endocrinology and male infertility. The following sections cover the diagnosis of different causes of infertility and the various assisted reproductive techniques (ART) available. Separate chapters discuss fertility preservation in gynaecologic cancer patients, and laboratory set up for IVF. The second edition has been fully revised and new topics added to provide the latest advances in the field. The comprehensive text is further enhanced by more than 200 clinical photographs, diagrams and tables. Key points Complete guide to infertility management for clinicians and trainees Fully revised second edition with new topics included Features more than 200 clinical photographs, diagrams and tables Previous edition (9789350255186) published in 2011

This book is a synopsis of the key facts and concepts of human development. It is intended for students who are taking a human embryology course. The book includes the underlying mechanisms involved in clinically important congenital anomalies that will prove useful to medical and nursing.

This timely resource offers extensive discussions on the pharmacological, environmental, endocrinological, and natural factors that alter reproductive or developmental processes-elucidating the effects of toxicants on mechanisms of reproduction. Describing biological actions common to both genders as well as gender-specific processes, Reproductive and Developmental Toxicology -provides an overview of the basic biology and physiology of organ systems affected by toxicants -furnishes detailed examples of developmental toxicology -analyzes germ cell toxicity and infertility -covers the developmental effects of neurotoxicity -considers periods of exposure and long-term toxicological consequences -explains how gonadal processes may be susceptible to toxicants in other reproductive organ systems -and more! With over 3700 bibliographic citations and more than 100 photographs, drawings, and tables, Reproductive and Developmental Toxicology is a useful reference for toxicologists; reproductive, developmental, cell, and molecular biologists; endocrinologists; biochemists; obstetricians/gynecologists; pediatricians; pharmacists and pharmacologists; physiologists; geneticists; poison control specialists; and upper-level undergraduate, graduate, and medical school students in these disciplines.

This is a comprehensive, up-to-date, authoritative research text and clinical reference work the menopause. It contains over 90 contributions covering every conceivable topic in the management of the menopause in women and related issues in the aging male. The book contains many illustrations and a wealth of references.

Female Puberty: A Comprehensive Guide for Clinicians is a practical reference, covering the full range of issues related to pubertal development. Developed to answer pointed clinical questions and to provide a thorough review of the literature, the book covers both the basics and the complexities of puberty, encompassing psychosocial development to pubertal nuances in highly specialized populations. Comprehensive in scope, this title offers concepts that are concisely conveyed and chapters that complement each other well. Complex subjects such as details of the hypothalamic-pituitary-ovarian axis are covered in a readily understandable manner and bullet points throughout the text serve as helpful reminders to the reader. An invaluable contribution to the literature, Female Puberty: A Comprehensive Guide for Clinicians will be of great interest to all health providers concerned with female reproductive health - including obstetrician gynecologists, reproductive endocrine specialists, pediatricians, pediatric specialists, family practitioners and allied health professionals.