This timely resource offers extensive discussions on the pharmacological, environmental, endocrinological, and natural factors that alter reproductive or developmental processes-elucidating the effects of toxicants on mechanisms of reproduction. Describing biological actions common to both genders as well as gender-specific processes, Reproductive and Developmental Toxicology -provides an overview of the basic biology and physiology of organ systems affected by toxicants -furnishes detailed examples of developmental toxicology -analyzes germ cell toxicity and infertility -covers the developmental effects of neurotoxicity -considers periods of exposure and long-term toxicological consequences -explains how gonadal processes may be susceptible to toxicants in other reproductive organ systems -and more! With over 3700 bibliographic citations and more than 100 photographs, drawings, and tables, Reproductive and Developmental Toxicology is a useful reference for toxicologists; reproductive, developmental, cell, and molecular biologists; endocrinologists; biochemists; obstetricians/gynecologists; pediatricians; pharmacists and pharmacologists; physiologists; geneticists; poison control specialists; and upper-level undergraduate, graduate, and medical school students in these disciplines.

Written by the authors of the renowned embryology textbooks The Developing Human and Before We Are Born, Concise Clinical Embryology: An Integrated, Case-Based Approach offers essential, high-yield information and high-quality clinical cases to illustrate key principles of embryology and their relevance to everyday practice. Ideally tailored to the needs of today's medical students and medical courses, this concise text clearly explains how embryology relates to other medical disciplines and its importance in safe, effective clinical practice. Abundant illustrations throughout help you grasp highly visual concepts quickly and easily. Provides easily digestible, clinically oriented coverage of human development, establishing key principles in a week-by-week, stage-by-stage approach, before moving on to fetal organ development by body system. Includes clinical cases and follow-up questions in each chapter that help relate key principles to everyday practice, aid in problem-based learning, and offer review for exam preparation. Covers the latest advances in embryology, including normal and abnormal embryogenesis, causes of birth defects, and the role of genes in human development. Contains superb illustrations from cover to cover, including diagnostic images, full color figures, histology, and more. Summarizes molecular biology highlights throughout the text. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access 18 3D animations with expert commentary, plus all of the text, figures, and references from the book on a variety of devices.

This book stems from the author's clinical experience working with infertile women in psychotherapy and psychoanalysis. It highlights the crucial importance of integrative work of psychotherapists and psychoanalysts with reproductive medical specialists in assisted reproductive technology (ART).

This is a comprehensive, up-to-date, authoritative research text and clinical reference work the menopause. It contains over 90 contributions covering every conceivable topic in the management of the menopause in women and related issues in the aging male. The book contains many illustrations and a wealth of references.

Human papillomavirus (HPV) is a major cause of cervical cancer. Human Papillomavirus Infections in Dermatovenereology pulls together the diverse disciplines of clinical, molecular biological, socio epidemiological, and immunological research to bridge the gap between the clinical aspects and basic biology of HPV. This volume provides a much-needed overview of the scientific and clinical data of HPV and HPV-associated diseases, exploring opinions on current therapies and diagnostic methods. It critically reviews the most frequently used molecular biologic methods, evaluating their potential in HPV detection. Specialists in dermatology, genitourinary medicine, gynecology, urology, as well as pathologists, microbiologists, epidemiologists, and virologists will appreciate this timely examination of the ubiquitous pathogen, HPV.

This important volume brings together findings in the psychological and medical treatment of sex offenders. It disseminates research from experts around the world in the field of sex offender treatment, making this knowledge available to researchers and clinicians everywhere. Professionals struggling to find effective methods for treating their patients will find Sex Offender Treatment a valuable tool for their daily work. Chapters in Sex Offender Treatment cover a variety of topics. Authors examine such areas as psychodynamic and psychiatric disorders associated with the sex offender, findings on pharmacologic interventions, treatment techniques and the public perception of sex offender treatment, and cautionary notes for those who provide therapy for sex offenders.Within these areas, some specific themes addressed include: types of personality disorders and implications for more effective treatment the effectiveness of antiandrogen treatment and the promising results of other pharmacotherapies techniques for developing insight in incest perpetrators a study of adult male incest offenders'perceptions of the treatment process an adolescent treatment program using a family communication approach hypotheses regarding sexual offenders and men who batter, using psychodynamic and feminist theory Full of practical strategies and useful information, Sex Offender Treatment is a book professionals will reach for again and again.

Prenatal Cocaine Exposures addresses the timely problem of maternal cocaine abuse and its effects on exposed infants, including growth retardation, learning, cardiovascular effects, and seizures. The impact of substance abuse on this and future generations presents an ongoing challenge to medical science. This comprehensive and authoritative volume reviews both animal and clinical studies to explain implications for treatment and long-term outcomes of early exposure.
Prenatal Cocaine Exposures investigates the specific role of cocaine in altering fetal development. Discussions of current studies and state-of-the-art techniques provide a basis for informed clinical decisions. Pediatricians, medical specialists, basic scientists, educators, and policy makers will all benefit from the comprehensive research gathered in this volume.

Written by a fertility nurse specialist and a sexual health information expert, What Every Woman Needs to Know About Fertility is the most comprehensive, practical and accessible guide to fertility awareness methods available.

This essential guide to reproduction puts you in control of your fertility by explaining how your body works, giving you the confidence to make informed decisions about your sexual and reproductive health. It answers every conceivable question about fertility awareness using detailed images, charts and a step-by-step guide to tracking your temperature and observing the bodily changes associated with ovulation, and gives clearly defined guidelines for how to plan, or avoid, a pregnancy.

Dispelling the myths around fertility awareness methods, and explaining the pros and cons of reproductive technologies such as fertility apps, this book also gives practical answers to the questions that all women ask, including:

• How reliable are Fertility Awareness Methods?
• How easy are FAMs to use?
• How can I use FAMs after having a baby?
• How can I use FAMs if I'm menopausal?

With insights into optimum health and preconception care, plus detailed practical advice to ensure the best possible conditions for pregnancy, What Every Woman Needs to Know About Fertility provides unique, comprehensive guidance and choices for all on how to plan or avoid pregnancy naturally.

In Reproduction, Technology, and Rights, philosophers and ethicists debate the central moral issues and problems raised by today's revolution in reproductive technology. Leading issues discussed include the ethics of paternal obligations to children, the place of in vitro fertilization in the allocation of health care resources, and the ethical implications of such new technologies as blastomere separation and cloning. Also considered are how parents and society should respond to knowledge gained from prenatal testing and whether or not the right to abort should relieve men of the duty to support unwanted children.
Reproduction, Technology, and Rights illuminates the moral and ethical choices that our society faces because of advances in reproductive technology and helps to make those decisions better informed.

This new edition is a complete guide to infertility management for specialists in reproductive medicine and trainees. Divided into 28 chapters, the book begins with an overview of the prevalence of infertility, female endocrinology and male infertility. The following sections cover the diagnosis of different causes of infertility and the various assisted reproductive techniques (ART) available. Separate chapters discuss fertility preservation in gynaecologic cancer patients, and laboratory set up for IVF. The second edition has been fully revised and new topics added to provide the latest advances in the field. The comprehensive text is further enhanced by more than 200 clinical photographs, diagrams and tables. Key points Complete guide to infertility management for clinicians and trainees Fully revised second edition with new topics included Features more than 200 clinical photographs, diagrams and tables Previous edition (9789350255186) published in 2011

This book describes the principles and skills of counselling. It provides practical guidelines which show, by example, how to communicate effectively, how to offer counselling and support, and how to face and deal with difficult situations. Detailed attention is given to issues such as preparing women for surgery, breaking bad news, and providing information and support before, during and after childbirth. The book aims to increase the awareness of health workers by describing a broad range on women's experiences and reactions to their particular problems and health concerns, as well as the ways in which these are treated.

In this work the eminent Dutch physician offers for the intelligent layman as well as for doctors, psychologists, teachers and social workers a guide to the causes and effects of fertility and sterility. This book is the third and last volume in Dr Theodoor Hendrik van de Velde's trilogy on the problems of marriage and this book completes his internationally authoritative work on eugenics and volitional sex behavior. Following his other book Ideal Marriage and Sexual Tensions in Marriage, this book considers such problems as sexual abstinence and excess, family limitation, the achievement of desired pregnancy, the causes and consequences, physically and emotionally, and sterility in women and impotence in men, artificial insemination, and the delicate personal and social aspects of undesired conception. Scientific in its approach and simple in its presentation, this book is for doctors and laymen. It offers information that contributes to a healthier understanding of voluntary and planned conception and helps safeguard happiness in marriage.

Female Puberty: A Comprehensive Guide for Clinicians is a practical reference, covering the full range of issues related to pubertal development. Developed to answer pointed clinical questions and to provide a thorough review of the literature, the book covers both the basics and the complexities of puberty, encompassing psychosocial development to pubertal nuances in highly specialized populations. Comprehensive in scope, this title offers concepts that are concisely conveyed and chapters that complement each other well. Complex subjects such as details of the hypothalamic-pituitary-ovarian axis are covered in a readily understandable manner and bullet points throughout the text serve as helpful reminders to the reader. An invaluable contribution to the literature, Female Puberty: A Comprehensive Guide for Clinicians will be of great interest to all health providers concerned with female reproductive health - including obstetrician gynecologists, reproductive endocrine specialists, pediatricians, pediatric specialists, family practitioners and allied health professionals.

Mind Over Bladder is a trusted and informative guidebook for bladder control, written with respect and humor by a nationally known urogynecologist, revised and expanded for the 21st century woman. Urinary Incontinence plagues millions of women worldwide, vastly more women than men. The reasons for this are many, including we have children, go through menopause and our anatomy is pretty different. Since these issues affect approximately 30-40% or greater of all women, can include issues with prolapsing organs (bladder, uterus, rectum) and can limit a woman's freedom and ability to live a full and active life, an actual guidebook seemed not only necessary but overdue. Mind Over Bladder answers this need. Informative, respectful and written with humor by a leading urogynecologist, Mind Over Bladder asks and answers the question of "What is incontinence and what can I do about it?". This unique approach begins at the beginning takes women through basic bladder and pelvic plumbing to getting a diagnosis and formulating a treatment plan. Mind Over Bladder arms women with information and practical solutions to help lead better, drier and happier lives.

This unique text provides a comprehensive yet concise review of the various environmental factors and lifestyle choices which impact male fertility, with special emphasis on the mechanisms that contribute to decreased sperm production and impaired function. Internationally recognized scientists and clinicians, leaders in the field of infertility, gather their insights and discuss how to prevent, address and cure male infertility caused by factors such as smoking, alcohol consumption, medication and drug use, obesity, dietary and exercise habits, sexually transmitted infections, psychological stress and occupational exposure to chemicals and radiation. Written in an easy to follow, informal yet scientific style, "Male Infertility" offers invaluable clinical guidelines for physicians and infertility experts and new data and research of great interest to basic scientists, andrologists and embryologists.

How do men react to diagnosis of male infertility and how, if at all, are all their lives affected by it? Male infertility is commonplace yet the male experience of it has been woefully neglected. "Male Infertility - Men Talking" explores these issues by gathering together men's stories and seeing what common strands, if any, exist between them. Mary-Claire Mason explores the past and present medical management of male infertility as this forms an essential backdrop to the men's stories but the main emphasis is on how men's lives are affected. In the first half of this book, the discovery of sperm and the man's role in reproduction is considered together with a review of how the past affects the present medical management of male infertility and the problems that bedevil it. The male voice predominates in the second half, speaking of painful events and relationships with families and friends, their feeling of isolation, their medical experiences, the importance of biological fatherhood, and their hopes for the future.

Published in 1998, this book is a collected volume of papers from the first conference of the European Network for Biomedical ethics. The main subject of this conference is the ethical assessment of IVF in view of its concrete application as an infertility treatment and the consideration of possible alternatives for use. Twenty years after the introduction and the establishment of this therapy a more concrete evaluation of its medical indications, social conditions and consequences, the psychological consequences for the women involved and the parent-child relationship becomes possible. The legal and ethical evaluation of the reproduction technology as regards for example the legal and moral status of supernumery embyos in cryo-conservation has also to be considered in a European perspective. The ethical evaluation concentrates today on the new evolution that IVF technology takes in relation to the extension of diagnostics possibilities due to genetic research. Little work has been done on the connection between IVF and genetic diagnostics and therapy, so the medical and ethical evaluation of the connecting lines are also included in the book.

This book outlines the current understanding of how obesity affects female reproductive function across the lifespan. Topics include physiology of the menstrual cycle and early pregnancy, best practices in the delivery of contraceptive and prenatal care and healthcare policy that weighs the evidence in appropriate balance with principles that respect women's rights. Special attention is devoted to the idea that obesity's adverse effects are likely trans-generational; that is, children born to obese mothers are at increased risk for obesity, diabetes and cardiovascular disease later in life. Patients and their physicians need to be aware of the additional risks obesity confers in pregnancy and outline a plan of care that includes counseling preconceptionally, antepartum, intrapartum and postpartum in order to decrease morbidity. Obesity and Fertility provides advice for reproductive medicine physicians and gynecologists to help guide obese patients toward improved reproductive health and outcomes.

This collection of essays, with an extended commentary by the editor, is concerned with developments in reproductive technology and the possibilities of genetic engineering. The volume provides a forum for debate between science and society. Leading scientists in the field explain the nature and goals of "test tube" reproduction and genetic engineering, and their eugenic implications. Other papers draw out the legal and ethical problems raised by these developments. The ethical dilemmas are discussed both from the point of view of secular moral philosophy and from a theological perspective. The extended commentary attempts to place these questions in the context of a social ethic, rather than an individualist one, in contrast to the approach adopted by the Warnock Report.

What does modern medical science know about menstruation? The menstrual cycle is less well understood by physicians than is commonly assumed and medical understanding of disorders associated with it are also limited. This study challenges the orthodox thinking in both society and medicine on menstruation. The authors base their study on women's own experiences and accounts of menstruation and menstrual disorders, drawing on a wide range of studies including their own. The book shows that women are often socialized to interpret the menstruum in negative terms and as something essentially private to be contained within the female domain. Taking an unorthodox approach, the authors incorporate a discussion of how menstruation is perceived within male culture and how the perspective of the medical profession has remained discernibly patriarchal. They show the significance of this in relation to women's experience within the family and at work. They end the book by focusing on the medicalisation of menstruation and the advantages and disadvantages for women of the greater access to the sick role this development implies.

This unique textbook is designed to provide a summary of state of the art developments in both male and female fertility and its association with cancer for both new and experienced practitioners. Clear, concise and readable, the text allows the reader to obtain rapid answers to this challenging medical issue. Special emphasis is placed on diagnostic and treatment algorithms. Topics covered include demographics of cancer in the reproductive age male, fertility conditions which predispose to cancer development, the role of assisted reproduction for fertility management, as well as fertility preservation strategies for the male and female cancer patients. Cancer and Fertility will be of great value to general urologists, uro-oncologists, gynecologists, medical oncologists, obstetricians, primary care providers, allied health providers.

Intrauterine development and birth constitute an uninterrupted sequence of events that have a molecular physiologic background. Perinatal Biochemistry presents a comprehensive review of this subject. Specific topics addressed include maternal metabolism during pregnancy, maternal insulin resistance, embryonic and fetal metabolism and fuel consumption, the fetal pancreas, growth factors, brain metabolism, and biochemical adaptations to early extrauterine life. The book will be useful to biochemists and physiologists interested in perinatology; clinicians working in areas related to maternal health, gestational development, and delivery; gynecologists, neonatologists; pediatricians; endocrinologists; and internists.

This work is based on the proceedings of the seventh conference of the Society for Menstrual Cycle Research held at the University of Michigan in Arbor in June 1987. It discusses such topics as the experience of menstruation, perimenstrual symptoms and premenstrual syndrome and menopause.

This book discusses the nature of meiotic chromosome pairing effects which may play a role in the determination of fertility. In particular, data and illustrations from the application of recently developed electron microscopic spreading techniques will allow researchers in related fields to come to grips with the recent advances in the cytogenetics of meiotic chromosome pairing behavior. Topics dealt with include meiotic and synaptonemal complex behavior in humans and mice with a variety of chromosomal and genetic abnormalities, sex chromosome pairing in mammals and birds, the significance for fertility or pairing in mammals and birds, the significance for fertility of XY pairing and crossing over, the effects of hybridity on pairing and fertility in plants, and the genetic control of synaptonemal complex formation and crossing over in polyploids. This is a timely reference book for graduate level medical and veterinary students, and scientists in the field of genetics and cell biology.

A comprehensive survey of the use of ultrasound in management of infertile patients is presented in this publication. Particular atten-tion is given to recently developed techniques such as assessment of endometrial changes, ovarian blood flow measurements, and per-cutaneous oocyte retrieval for in vitro fertilization. The very re-cent technique of transvaginal sonography is presented and richly illus-trated with original results obtained in biopsy-guided oocyte re-trieval, and in the precise delineation of follicle size and number for infertility treatment. Guidance in the interpretation of ultrasonic findings, which include potential limitations and pitfalls, is provided in each chapter. Researchers and practitioners interested in the management of infertile patients will find this volume indispensable.