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Books > Medicine > Pre-clinical medicine: basic sciences > Human reproduction, growth & development > Reproductive medicine
The editor of this volume takes on the challenging task of
presenting an encompassing view of childbirth in America from an
anthropological perspective. The book is indeed comprehensive. . .
. Collectively the chapters in Childbirth in America lay out a
representative sketch of research problems of interest to
sociocultural anthropologists and other social scientists working
in the area of reproductive health. A distinct accomplishment is
the acknowledgement in some of the chapters that not all American
women want the same kind of childbirth care or have the same values
and attitudes about pregnancy, birth, and parenting, and that this
variation needs addressing in both childbirth policy and practice.
American Journal of Physical Anthropology A comprehensive and
critical examination of the experience of childbirth in America
today, from pregnancy to early postpartum. This book covers many
controversial issues in the context of diverse cultural, social,
and economic backgrounds, which have arisen as a result of the new
technologies and ideologies surrounding pregnancy and birth. Most
useful as a text for courses in childbirth education, anthropology
of women's health, and anthropology of medicine.
This atlas comprises a complete and extensive exposure of the
spatial and temporal aspects of human cardiac development as seen
with scanning electron microscopy. Apart from serving as a unique
overview on cardiac development in the human embryo, this atlas
gives an updated morphological reference of cardiac embryology for
topographic correlation and enables the projection of experimental
results in animals to the human situation.
Arthur L. Caplan It is commonly said, especially when the subject
is assisted reproduction, that medical technology has out stripped
our morality. Yet, as the essays in this volume make clear, that is
not an accurate assessment of the situ ation. Medical technology
has not overwhelmed our moral ity. It would be more accurate to say
that our society has not yet achieved consensus about the complex
ethical iss ues that arise when medicine tries to assist those who
seek its services in order to reproduce. Nevertheless, there is no
shortage of ethical opinion about what we ought to do with respect
to the use of surrogate mothers, in vitro fertil ization, embryo
transfer, artificial insemination, or fertil ity drugs. Nor is it
entirely accurate to describe assisted repro duction as technology.
The term "technology" carries with it connotations of machines
buzzing and technicians scurrying about trying to control a vast
array of equip ment. Yet, most of the methods used to assist
reproduc tion that are discussed in this volume do not involve
exotic technologies or complicated hardware. It is technique, more
than technology, that dominates the field of assisted reproduction.
Efforts to help the infertile by means of the manipu lation of
human reproductive materials and organs date 1 2 Caplan back at
least to Biblical times. Human beings have en gaged in all manner
of sexual practices and manipulations in attempts to achieve
reproduction when nature has balked at allowing life to begin."
The purpose of this third edition of Developmental and Reproductive
Toxicology is to provide a practical guide to developmental and
reproductive toxicology in a regulatory environment. In addition to
a comprehensive update of current chapters, the third edition been
revised to reflect recent changes in the field. It contains new
chapters that reflect emerging topics of interest, including
testing of biologics (including vaccines), nonhuman primates as
nonclinical models, developmental immunotoxicity testing, in vitro
assays (such as use of zebrafish and stem cells, as well as high
throughput screening), in silico systems modelling, evaluating
mechanisms of reproductive toxicity, in-depth coverage of
neurobehavioral testing, and testing under the EU's REACH
regulations, as well as updated chapters on nonclinical juvenile
toxicity testing, endocrine disruptor screening, and on functional
and computational genomics. The study of hazard and risk associated
with exposure to toxicants during prenatal development has been
expanded in recent years to include effects on development until
the time of puberty. Concern over the adverse effects of chemical
or physical agents on the reproductive processes of both sexes has
increased, and progress has been made in identifying the causes and
mechanisms eliciting congenital defects and determining the
genetic, epigenetic, and environmental factors involved. This book
provides up-to-date guidance on the use and interpretation of the
newest research techniques in developmental and reproductive
toxicology, as well as the more traditional approaches.
Developmental and Reproductive Toxicology, Third Edition: Contains
valuable insights gained from hands-on experience, together with a
critical evaluation of current testing strategies. Includes
guidance for the design, conduct, and interpretation of tests in
all areas of developmental and reproductive toxicity. Contains
reprinted guidelines from major regulatory agencies, as well as
terminology for description of developmental abnormalities in
laboratory animals, for easy reference. Provides guidance for
planning and conducting preclinical toxicity studies and follow-up
studies, and interpreting their results in a regulatory
environment. This book continues to be the ideal practical
reference for developmental and reproductive toxicologists who
perform research in industry, government, and academia and for
anyone who intends to enter these research areas.
This expansive survey spotlights pervasive issues affecting girls'
and women's sexual and reproductive health across the lifecourse.
Research from diverse countries around the world analyzes the
complex relationships among biological, psychological,
sociocultural, and economic issues-particularly in terms of
inequities-as they shape women's lives. Major challenges and
possibilities for intervention are examined in their national
context and with their global implications, including child
marriage/motherhood, reproductive care and access, fertility,
childbearing, contraception, abortion, HIV/STIs, gender-based
violence, sexual pleasure, and menopause. In these forceful
dispatches, a consistent human rights perspective emphasizes
women's control, autonomy, and agency in all stages of their lives.
A sampling of topics covered: Girl child marriage: a persistent
global women's health and human rights violation Investigating
challenges and resilience among women living with obstetric fistula
in Kenya A qualitative exploration of mainstream and social media
reflections on abortion A continuum of severity of sexual intimate
partner violence among black women in the United States Economic
empowerment to improve sexual and reproductive health among women
and girls Summarizing an interdisciplinary field on research and
practical levels, Global Perspectives on Women's Sexual and
Reproductive Health Across the Lifecourse will be an invaluable
text for undergraduate and graduate courses in a wide range of
fields, including public health, global health, women's studies,
sociology, anthropology, gender studies, and human rights.
Breast Care: A Clinical Guidebook for Women's Primary Health Care
Providers presents the expertise and protocols of the renowned
Breast Diagnostic Center at USC School of Medicine's Department of
Obstetrics and Gynecology. A user-friendly reference for the
primary care physician, this book details the management of both
benign and malignant breast diseases. Topics include: * the
clinical examination and instruction for self-exam * mammography
for both screening and diagnosis, management of the abnormal
mammogram * lactation and breast feeding * diagnosis and treatment
of lumps, cysts, fibroadenomas * fine-needle aspiration and
ultrasound guided tissue core needle biopsy * evaluation and
management of mastalgia * menstrual and hormonal therapy effects on
the breast * the cosmetically treated breast * guidelines for
follow-up and surveillance An important section on consultation and
referrals reviews the roles of the radiologist, oncologist, and
surgeon and provides the primary care physician with the
information necessary to counsel the patient on the myriad aspects
of multidisciplinary treatment planning. The text includes more
than 100 illustrations and algorithms -- with 16 in color -- as
well as "Practice Guides" which organize the key practice points,
signs, and symptoms. This is a must-have handbook for all providers
of health care to women.
This second edition emphasizes the environmental impact on
reproduction, with updated chapters throughout as well as complete
new chapters on species such as sharks and rays. This is a
wide-ranging book that will be of relevance to anyone involved in
species conservation, and provides critical perspectives on the
real utility of current and emerging reproductive
sciences.Understanding reproductive biology is centrally important
to the way many of the world's conservation problems should be
tackled. Currently the extinction problem is huge, with up to 30%
of the world's fauna being expected to disappear in the next 50
years. Nevertheless, it has been estimated that the global
population of animals in zoos encompasses 12,000 - 15,000 species,
and we anticipate that every effort will be made to preserve these
species for as long as possible, minimizing inbreeding effects and
providing the best welfare standards available. Even if the
reproductive biology community cannot solve the global biodiversity
crisis for all wild species, we should do our best to maintain
important captive populations. Reproductive biology in this context
is much more than the development of techniques for helping with
too little or too much breeding. While some of the relevant
techniques are useful for individual species that society might
target for a variety of reasons, whether nationalistic, cultural or
practical, technical developments have to be backed up by thorough
biological understanding of the background behind the problems.
The Project on Reproductive Laws for the 1990s began in 1985 with
the realization that reports of scientific developments and new
technologies were stimulating debates and discussions among
bioethicists and policymakers, and that women had little part in
those discussions either as participants or as a group with
interests to be considered. With the help of a planning grant from
the Rutgers University Institute for Research on Women, the Women's
Rights Litigation Clinic at Rutgers University Law School-Newark
held a planning meeting that June attended by approximately 20
theorists and activists in the area of reproductive rights. Project
purposes, methods, and general shape took form at the meeting. Two
goals have characterized the Project's work since then: first, to
generate discussion, debate, and, where possible, consensus among
those committed to reproductive autonomy and gender equality as to
how best to respond to the questions raised by re ported advances
in reproductive and neonatal technology and new modes of
reproduction; and second, to ensure that those shaping reproductive
law and policy appreciate the ramifications of these developments
for gender equality. In meeting this twofold agenda, the Project
focused on six areas: time limits on abortion; prenatal screening;
fetus as patient; reproductive hazards in the workplace;
interference with reproductive choice; and alternative modes of
reproduction. The Project identified individuals to take respon
sibility for drafting model legislation and position papers in the
six areas (for the drafters, see the Appendix)."
This book grew out ofmy interest in what is often called "the
immunological paradox ofpregnancy." How is it possible that the
fetus-halfofwhosegenetic apparatuscomesfrom thefather and is
foreign to the mother-can survive to term? This is a question that
intrigues all immunologists. For me, it has been of interest ever
since I heard a lecture on the subject in medical school, long
before I thought ofbecoming a "professional immunologist." Indeed,
the question ofthe immunological aspect of fetal survival (or
demise) should be of interest to any biologist or physician. The
question becomes broader ifone considers the immunologic relations
between motherand fetus, because they represent a unique symbiotic
union. Whatimmunologic problemsinthemothermayaffecttheoffspring,
and isitpossiblethatfetal immunology willaffectthe mother? Finally,
there is the question ofwhether immunology is important in recur-
rent spontaneous abortion. Every authorowes the reader a general
oversightofthe book in hand, indicating the terrain to be covered,
and, by inference, the territory that will not be explored. 1. This
is primarily a book for clinicians. I will only men- tion animal
experiments and data in passing, and as they may illuminate a
clinical problem or observation. 2. The interest here is the
immunology ofmaterno--fetal re- lations, once a pregnancy has
begun. Therefore, I will notcover immunological aspects
ofsterility, nor touch on the immunological approaches to
controlling fer- tility, i.e., "contraceptive vaccines." 3. This is
a book mainly concerned with pathogenesis.
This unique book is a comprehensive guide for healthcare providers
who treat patients with complex medical conditions but lack the
resources to address fertility and sexuality concerns and help
patients navigate their fertility decision-making process. It
presents up-to-date information concerning fertility preservation
and restoration for patients with hereditary cancer syndromes,
disorders of sex development, hematologic diseases, genetic
disorders of gonadal dysfunction, immunologic diseases, gynecologic
diseases, endocrine disorders, and autoimmune and inflammatory
diseases. Utilizing a practical, user-friendly format, each chapter
discusses the epidemiology, classification, risk factors and/or
clinical manifestations, and diagnosis and treatment modalities
specific to each condition, as well as the effect of it or its
treatment on fertility and unique options that may exist. Complex
medical conditions are inherently difficult to manage, and
reproductive interventions are often not part of the conversation.
As such, Fertility Preservation and Restoration for Patients with
Complex Medical Conditions will be an excellent resource for
primary care physicians, obstetrician/gynecologists,
endocrinologists, oncologists, and other health professionals
working with patients with fertility concerns. This book, together
with Oncofertility: Fertility Preservation for Cancer Survivors;
Oncofertility: Ethical, Legal, Social, and Medical Perspectives;
Oncofertility Medical Practice: Clinical Issues and Implementation;
Oncofertility Communication: Sharing Information and Building
Relationships across Disciplines; and Pediatric and Adolescent
Oncofertility: Best Practices and Emerging Technologies, provides
scientific and medically relevant information on fertility
preservation from all vantage points and is an indispensable series
for those interested in fertility management in cancer or complex
settings.
To what extent should parents be able to choose the kind of child
they have? The unfortunate phrase 'designer baby' has become
familiar in debates surrounding reproduction. As a reference to
current possibilities the term is misleading, but the phrase may
indicate a societal concern of some kind about control and choice
in the course of reproduction. Typically, people can choose whether
to have a child. They may also have an interest in choosing, to
some extent, the conditions under which they do so, such as whether
they have a child with a serious disability or disease. The purpose
of this book is to explore the difficult and controversial question
of the appropriate ethical and legal extent of reproductive
autonomy in this context. The book examines ethical, legal and
public policy issues in prenatal screening, prenatal diagnosis
(PND), selective abortion and preimplantation genetic diagnosis
(PGD). It explores the ethics of these selection practices and the
ability of current ethical guidelines and legal mechanisms,
including the law on selective abortion and wrongful birth, to deal
with advances in genetic and other knowledge in these areas. Unlike
in the United States, in England the relevant law is not inherently
rights-based, but the impact of the Human Rights Act 1998
inevitably raises questions about the proper scope of reproductive
autonomy in this context. The implications of the analysis are
considered for the development of relevant law, public policy and
ethical guidelines and will be of interest to academics in medical
law and ethics, health professionals, lawyers, those working on
public policy and students with an interest in these issues.
Brantlinger discusses the current medical and legal trends in
sterilization with special emphasis on people with disabilities.
She explores the issues surrounding sterilization decisions from
the perspectives of judges, lawyers, social workers, doctors,
family planners, as well as the families and individuals
themselves. Woven throughout the book are case studies of
individuals ranging from mild to severe retardation.
Brantlinger discusses the current medical and legal trends in
sterilization with special emphasis on people with disabilities.
She explores the issues surrounding sterilization decisions from
the perspectives of judges, lawyers, social workers, doctors,
family planners, as well as the families and individuals
themselves.
Woven throughout the book are case studies of individuals
ranging from mild to severe retardation. She illustrates how
ethical issues related to sterilization are framed and which moral
values are called upon during decision-making. She ends with
guidelines for decision-making. As the most comprehensive and
up-to-date work on the subject, this book will be invaluable to
professionals in the social services and mental health fields as
well as researchers in law, special education, social work, and
public health. Individuals confronting these concerns will find the
volume instructive as well.
Reproductive health care professionals in fields such as Obstetrics
and Gynecology, Family Medicine, and Pediatrics face difficult
ethical issues because they work at the crossroads of patient
decision-making, scientific advancement, political controversy,
legal regulation, and profound moral considerations. The dilemmas
these professionals face expose big-picture bioethics questions of
interest to everyone. Yet for clinicians striving to deliver
excellent patient care, the ethical questions that make daily
practice challenging can be just as nuanced. This volume presents a
carefully curated compilation of essays written by leading experts
in the fields of medicine, ethics, and law, who address key issues
at the forefront of reproductive ethics. It is organized into three
main sections: I. Contraception and Abortion Ethics - Preventing
Pregnancy and Birth, II. Assisted Reproduction Ethics - Initiating
Pregnancy, and III. Obstetric Ethics - Managing Pregnancy and
Delivery. Each section begins with a short introduction by the
editors providing an overview of the area and contextualizing the
essays that follow. This volume's primary aim is to be useful to
practicing clinicians, students, and trainees by providing short
and practical essays covering urgent topics-from race, religion and
abortion, to legal liability, violations of confidentiality and
maternal choices that risk future children's health. This
collection provides clinicians at all levels of training with
frameworks they need to approach the intimate and high-stakes
encounters central to their profession.
This book provides an overview of the role and function of
regulatory RNAs that lack protein-coding potential in key
reproductive tissues. This includes the role of small interfering
RNAs (siRNAs), microRNAs (miRNAs), PIWI-interacting RNAs (piRNAs),
small nucleolar RNAs (snoRNAs) and long non-coding RNAs (lncRNAs).
Through clear, detailed and comprehensive debate, international
leading experts discuss the role these novel regulators in normal
development of sexual dimorphisms, including the differentiation of
ovaries and testes, the genital tract including prostate,
epididymis and uterus, as well as mammary glands. In addition,
particular attention is paid on their role in pathophysiological
processes within the reproductive tract. The power of next
generation sequencing has proved to be an invaluable tool to
discover new non-coding RNAs. While the identification of
non-coding RNA is relatively easy, analysing their function
represents still a challenge today. In this book, authors present
historical and conceptual background information, highlight the
ways in which non-coding RNAs function is analysed and present
their vision of the future research in their key research area.
This book presents a timely collection of reviews by experts in
periconception and fertilization. The book provides a good
introduction for those new to the field as well as those who have
worked in this field for some time, but not have been able to keep
up-to-date with recent advances on the topic. The book reviews the
current knowledge in this field, then focuses its attention on
short-term and long-term effects of the periconception period, both
from a physiological and medical perspective. Finally the volume
covers the examination of the potential mechanisms involved in
controlling periconception period. From the early days of discovery
about the basics of the fertilization process, scientists have
known that early events happening during conception play a major
part in the creation of new offspring. However, until nearly a
decade ago we thought these events were just concerned with the
conception and nothing to do with lifelong health and welfare, or
wellbeing of the offspring. Early indications from IVF in sheep and
cattle suggested that the embryo culture conditions employed in the
laboratory could result in unusually large and unhealthy offspring.
These observations sounded alarm bells and stimulated research into
the impacts of in vivo and in vitro conditions on the health of
embryos and offspring. This book provides a summary of the
state-of-the-art research being done to more fully understand the
importance of the periconception environment.
All persons, while different from one another, have the same value:
this is the author's relatively uncontroversial starting point. Her
end point is not uncontroversial: an ideal of justice as human
flourishing, based on each person's unique set of capabilities.
Because the book's focus is women's health care, gender justice, a
necessary component of justice, is central to examination of the
issues. Classical pragmatists and feminist standpoint theorists are
enlisted in support of a strategy by which gender justice is
promoted. Two features of the book are unique: (1) the topics
presented cover the entire life span of women, not just those
related to reproduction; (2) a range views about moral status are
applied not only to fetuses but also to individuals already born.
Attention to these features is intended to facilitate ethical
consistency or moral integrity and respect for those who hold
different moral views. While delineating and defending the book's
perspective, the first section provides an overview of bioethics,
critiques prevalent approaches to bioethics and models of the
physician-patient relationship, and sketches distinguishing aspects
of women's health care that are prevalently neglected. Positions
about moral status are also presented. The second section
identifies topics that are indirectly as well as directly related
to women's health, such as domestic violence and caregiving. Brief
cases illustrate variables relevant to each topic. Empirical and
theoretical considerations follow each set of cases; these are
intended to precipitate more expansive and critical examination of
the issues raised. The last section is devoted to an egalitarian
ideal that may be pursued throughan ethic of virtue or
supererogation rather than obligation. By embracing this ideal,
according to the author, moral agents support a more demanding
level of morality than guidelines or laws require.
How do rapid social and technological changes shape reproductive
realms today? This book considers the complex choices, anxieties
and challenges that come alongside postmodern reproduction for
women and men in the West. Topics include surrogacy, fatherhood,
sperm banking, egg donation, contraception, breastfeeding, and
postpartum body image.
This important volume brings together findings in the psychological
and medical treatment of sex offenders. It disseminates research
from experts around the world in the field of sex offender
treatment, making this knowledge available to researchers and
clinicians everywhere. Professionals struggling to find effective
methods for treating their patients will find Sex Offender
Treatment a valuable tool for their daily work. Chapters in Sex
Offender Treatment cover a variety of topics. Authors examine such
areas as psychodynamic and psychiatric disorders associated with
the sex offender, findings on pharmacologic interventions,
treatment techniques and the public perception of sex offender
treatment, and cautionary notes for those who provide therapy for
sex offenders.Within these areas, some specific themes addressed
include: types of personality disorders and implications for more
effective treatment the effectiveness of antiandrogen treatment and
the promising results of other pharmacotherapies techniques for
developing insight in incest perpetrators a study of adult male
incest offenders'perceptions of the treatment process an adolescent
treatment program using a family communication approach hypotheses
regarding sexual offenders and men who batter, using psychodynamic
and feminist theory Full of practical strategies and useful
information, Sex Offender Treatment is a book professionals will
reach for again and again.
The average physician and even cancer care-givers are not
knowledgeable about the effects of cancer treatment on sex and
reproductive life. They are even less aware of the options
available for treatment of such patients. "Cancer and Sexual
Health" fills a great need for a reference work devoted to the link
between cancer and human sexuality. The volume is designed to give
a comprehensive and state-of-the-art review of the sexual and
reproductive consequences of cancer diagnosis and treatment. It
will prove an invaluable resource for those clinicians caring for
cancer patients as well as acting as a reference text for the
sexual medicine clinician who may not see a large number of cancer
patients.
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