Erectile dysfunction is a common problem that may result from a number of medical conditions. With increasing public awareness, men with ED are seeking medical help. This pocketbook will assist the physician in treating and managing ED effectively with either drugs or devices.

It is over two decades since the first test-tube baby was born. During this period a new belief that all infertile women can now have babies has become widely accepted; indeed, infertile couples may feel great pressure to seek a medical solution. However, the psychological and social effects of the changing experiences of infertility remain confusing, both for those who experience infertility and for wider society. In this book, a distinguished range of contributors, including novelist Hilary Mantel and Germaine Greer, examine the experience of infertility from both male and female perspectives, the psychological aspects of infertility diagnosis and treatment, and the often radical and unexpected effects on kinship.
Drawing from a wide range of theoretical backgrounds including Jungian, analytical, and compelling personal reflections, this book aims to unravel the implications of advancing reproductive technology for our understanding of ourselves and our families.

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Reproductive biologists, evolutionary biologists, demographers and social scientists all have a common interest in the business of human reproduction. Their perspectives, however, are very different and have traditionally prevented them from having much to do with each other. The conference on which this book is based brought together contributors from each of these disciplines in an attempt to explore the common ground that they share and so generate a better understanding of the factors that influence human fertility.

If you had a dependable method for determining the healthiest and most viable conceptus from a cohort of growing preembryos, replacing more than a single one in order to achieve good pregnancy rates would be moot. Sometime in the not-so-distant future, this may be a reality. Taking a step towards that future, An Atlas of Human Blastocysts vividly illustrates the typical and atypical morphology of mammalian blastocysts. The atlas demonstrates that extended culture of blastocysts is now achieveable in the laboratory and points us toward the day when it will be possible to choose between a number of healthy hatched blastocysts.

SEE THE ENTIRE RANGE OF STRUCTURAL DEVELOPMENT

A volume in the Atlas of Human Central Nervous System Development series, The Spinal Cord from Gestational Week 4 to the 4th Postnatal Month presents unique illustrations of structural development. With its clearly labeled photographs and extensive quantitative comparisons, you'll gain new insights into the steps involved in the morphogenesis of the mature spinal cord.

YOUR COMPLETE GUIDE TO NORMAL DEVELOPMENT

The first comprehensive study of its kind, the five-volume Atlas of Human Central Nervous System Development Series allows you to:

· Observe the complex structural processes that normally occur during human development
· Better evaluate neural developmental disorders
· Design experiments that more efficiently target the root causes of neural disorders

This book provides andrologists and other practitioners with reliable, up-to-date information on all aspects of male infertility and is designed to assist in the clinical management of patients. Clear guidance is offered on classification of infertility, sperm analysis interpretation and diagnosis. The full range of types and causes of male infertility are then discussed in depth. Particular attention is devoted to poorly understood conditions such as unexplained couple infertility and idiopathic male infertility, but the roles of diverse disorders, health and lifestyle factors and environmental pollution are also fully explored. Research considered stimulating for the reader is highlighted, reflecting the fascinating and controversial nature of the field. International treatment guidelines are presented and the role of diet and dietary supplements is discussed in view of their increasingimportance. Clinicians will find that the book s straightforward approach ensures that it can be easily and rapidly consulted."

A wide-ranging history of assisted reproductive technologies and their ethical implications. Finalist of the PROSE Award for Best Book in History of Science, Medicine and Technology by the Association of American Publishers Since the 1978 birth of the first IVF baby, Louise Brown, in England, more than eight million children have been born with the help of assisted reproductive technologies. From the start, they have stirred controversy and raised profound questions: Should there be limits to the lengths to which people can go to make their idea of family a reality? Who should pay for treatment? How can we ensure the ethical use of these technologies? And what can be done to address the racial and economic disparities in access to care that enable some to have children while others go without? In The Pursuit of Parenthood, historian Margaret Marsh and gynecologist Wanda Ronner seek to answer these challenging questions. Bringing their unique expertise in gender history and women's health to the subject, Marsh and Ronner examine the unprecedented means-liberating for some and deeply unsettling for others-by which families can now be created. Beginning with the early efforts to create embryos outside a woman's body and ending with such new developments as mitochondrial replacement techniques and uterus transplants, the authors assess the impact of contemporary reproductive technology in the United States. In this volume, we meet the scientists and physicians who have developed these technologies and the women and men who have used them. Along the way, the book dispels a number of fertility myths, offers policy recommendations that are intended to bring clarity and judgment to this complicated medical history, and reveals why the United States is still known as the "Wild West" of reproductive medicine.

Documenting the latest statistical data on current problems related to reproductive health issues in Central and Eastern Europe, this book explores the reasons for these problems and recommends action based on the scientific evidence for improving reproductive health.

The main issues covered in the book are: declining standards of reproductive health care; rising trends in the incidence of sexually transmitted diseases; low rates of use of modern contraceptives; high rates of induced abortion; high prevalence of infertility; and the needs of adolescents with regard to reproductive health.

The Cassell Hospital Monograph Series, No. 1. The first in a series of monographs, intended to present accessible teaching material concerned with the practice of residential care.

Human papillomavirus (HPV) is a major cause of cervical cancer. Human Papillomavirus Infections in Dermatovenereology pulls together the diverse disciplines of clinical, molecular biological, socio epidemiological, and immunological research to bridge the gap between the clinical aspects and basic biology of HPV. This volume provides a much-needed overview of the scientific and clinical data of HPV and HPV-associated diseases, exploring opinions on current therapies and diagnostic methods. It critically reviews the most frequently used molecular biologic methods, evaluating their potential in HPV detection. Specialists in dermatology, genitourinary medicine, gynecology, urology, as well as pathologists, microbiologists, epidemiologists, and virologists will appreciate this timely examination of the ubiquitous pathogen, HPV.

Doctors increasingly recognize that sexual unhappiness has serious effects on the health of individuals and families. Sexual function depends on our bodies and our minds and sexual problems may present with physical symptoms. Using case histories the book describes the practice of psychosexual medicine and explores the skills used by doctors therapists and counsellors. A systematic and comprehensive examination of this field for the first time this book places psychosexual medicine in context with other therapies. For those working at all levels throughout primary care including doctors and nurses in general practice and in family planning clinics therapists and counsellors and for specialists in the fields of genito-urinary medicine gynaecology andrology and urology Blocks and Freedoms in Sexual Life is an essential reference and a tool for increasing the scope and effectiveness of their work.

With technological advances in reproduction no longer confined to the laboratory or involving only the isolated individual, women and men are increasingly resorting to a variety of technologies unheard of a few decades ago to assist them in becoming parents. The public at large, and feminists as a group, are confused and divided over how to view these technologies and over what positions to take on the moral and legal dilemmas. The Other Machine provides a rigorous analysis of contemporary feminist debates.

The numbers of women undergoing Assisted Reproduction Technology (ART) treatments have risen steadily, yet they remain largely outside the scope of equality and employment law protection while undergoing treatment. Assisted Reproduction, Discrimination, and the Law examines this gap in UK law, with reference to EU law as appropriate, and argues that new conceptions of equality are necessary. Drawing from the literature on multidimensional and intersectional discrimination, it is argued that an intersectionality approach offers a more useful analytical framework to extend protection to those engaged in ART treatments. Drawing from Schiek's intersectional nodes model, the book critically examines two alternative interpretations of existing protected characteristics, namely infertility as a disability, with reference to the social model of disability and the UN Convention on the Rights of Persons with Disabilities 2006, and redefining the boundaries of pregnancy and/or sex discrimination, with reference to attempts to extend associative discrimination to pregnancy. Comparisons are drawn with the US, where infertility has been recognised as a disability under the American's with Disabilities Act 1990 and as a pregnancy-related condition under the Pregnancy Discrimination Act 1978. A specific right to paid time off work to undergo treatment is also proposed, drawing comparisons with the US Family and Medical Leave Act 1993 and the existing UK work-family rights framework. It is argued that the reinterpretations of equality law and the rights proposed here are not only conceptually possible, but could practically be achieved with minor, but significant, amendments to existing legislation.

Providing a comprehensive review of the interactions between exercise and human reproduction, this unique text focuses on both the positive and negative consequences of sport and physical activity on male and female fertility and infertility and the biological mechanisms and processes behind them. Beginning with a review of the structure and function of the male and female reproductive systems as well as fertilization and gestation, the discussion then turns to the physiology and endocrinology of sport and exercise, which is further elaborated in subsequent chapters on the impact of physical activity, hormonal changes, pathologies, and consequences of drug use for active men and women. Additional chapters address related topics, such as the impact of sport on young athletes and developing reproductive potential, physical activity and pregnancy, the use of oral contraceptives in athletes, oxidative stress, and the impact of nutritional deficiencies on athletes' fertility, with a final chapter providing recommendations and therapeutic guidelines for exercise-related reproductive disorders. Covering everything from the fundamental principles of sports physiology and human reproductive potential to the interaction between physical exercise and the endocrinology of the reproductive system, Exercise and Human Reproduction is an authoritative resource for helping clinicians understand how the reproductive system adapts to activity and exercise and offers strategies to avoid potential harm to human reproduction.

This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It summarizes the newest achievements on this topic from Notch's flag-ship function in the development of the embryo and for various inherited diseases to the Notch signaling pathway's role in the development of leukemia and in a number of cancers, including skin cancer, intestinal cancer and others. Additionally, the emerging new role of the Notch signaling pathway as a promising target for prevention and therapy of various diseases, including cancer, is discussed. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch's role for embryologic tissue patterning, for stem cells, in senescence, and on the regulation of Notch signaling by epigenetic and other factors including microRNAs, long non-codingRNAs, and more. Taken as a whole, with its companion books - Notch Signaling in Embryology and Notch Signaling in Cancer - this is a definitive discussion of the topic, presented by internationally-recognized contributors. Presented in a coherent and accessible structure, this revised and updated second edition is an essential and up-to-date guide for oncologists, embryologists, researchers and advanced students.

Reproductive health care professionals in fields such as Obstetrics and Gynecology, Family Medicine, and Pediatrics face difficult ethical issues because they work at the crossroads of patient decision-making, scientific advancement, political controversy, legal regulation, and profound moral considerations. The dilemmas these professionals face expose big-picture bioethics questions of interest to everyone. Yet for clinicians striving to deliver excellent patient care, the ethical questions that make daily practice challenging can be just as nuanced. This volume presents a carefully curated compilation of essays written by leading experts in the fields of medicine, ethics, and law, who address key issues at the forefront of reproductive ethics. It is organized into three main sections: I. Contraception and Abortion Ethics - Preventing Pregnancy and Birth, II. Assisted Reproduction Ethics - Initiating Pregnancy, and III. Obstetric Ethics - Managing Pregnancy and Delivery. Each section begins with a short introduction by the editors providing an overview of the area and contextualizing the essays that follow. This volume's primary aim is to be useful to practicing clinicians, students, and trainees by providing short and practical essays covering urgent topics-from race, religion and abortion, to legal liability, violations of confidentiality and maternal choices that risk future children's health. This collection provides clinicians at all levels of training with frameworks they need to approach the intimate and high-stakes encounters central to their profession.

Spermatogenesis involves the coordination of a number of signaling pathways, which culminate into production of sperm. Its failure results in male factor infertility, which can be due to hormonal, environmental, genetic or other unknown factors. This book includes chapters on most of the signaling pathways known to contribute to spermatogenesis. Latest research in germ cell signaling like the role of small RNAs in spermatogenesis is also discussed. This book aims to serve as a reference for both clinicians and researchers, explaining possible causes of infertility and exploring various treatment methods for management through the basic understanding of the role of molecular signaling. Key Features Discusses the signaling pathways that contribute to successful spermatogenesis Covers comprehensive information about Spermatogenesis at one place Explores the vital aspects of male fertility and infertility Explains the epigenetic regulation of germ cell development and fertility Highlights the translational opportunities in molecular signaling in testis

A much-needed overview of the available information now accumulating to indicate that assisted reproductive technologies are generally safe for both babies and mothers. However, the literature abounds with reports of a higher risk of obstetric and perinatal complications; regarding the long term outcomes for both women and children, the data are still scarce. The chapters summarized in this book review the current knowledge on long term safety of assisted reproduction and indicate the need for continued research to cover the lack of data in some specific patient groups and for recently developed treatments that only have a short period of follow-up.

A critical analysis of white, working class North Americans' motivations and experiences when traveling to Central Europe for donor egg IVF Each year, more and more Americans travel out of the country seeking low cost medical treatments abroad, including fertility treatments such as in vitro fertilization (IVF). As the lower middle classes of the United States have been priced out of an expensive privatized "baby business," the Czech Republic has emerged as a central hub of fertility tourism, offering a plentitude of blonde-haired, blue-eyed egg donors at a fraction of the price. Fertility Holidays presents a critical analysis of white, working class North Americans' motivations and experiences when traveling to Central Europe for donor egg IVF. Within this diaspora, patients become consumers, urged on by the representation of a white Europe and an empathetic health care system, which seems nonexistent at home. As the volume traces these American fertility journeys halfway around the world, it uncovers layers of contradiction embedded in global reproductive medicine. Speier reveals the extent to which reproductive travel heightens the hope ingrained in reproductive technologies, especially when the procedures are framed as "holidays." The pitch of combining a vacation with their treatment promises couples a stress-free IVF cycle; yet, in truth, they may become tangled in fraught situations as they endure an emotionally wrought cycle of IVF in a strange place. Offering an intimate, first-hand account of North Americans' journeys to the Czech Republic for IVF, Fertility Holidays exposes reproductive travel as a form of consumption which is motivated by complex layers of desire for white babies, a European vacation, better health care, and technological success.

The book considers signaling events from the zygote embryo through to the blastocyst with relevant data from embryonic stem (ES) cells, including dialogue with the extracellular environment and with the maternal tract during the implantation process. Application of the knowledge described to improve the success of human and animal assisted conception is considered where appropriate, but the focus is largely on fundamental rather than applied cell/molecular biology, as this is the area that has historically been neglected. While the general features of metabolism during preimplantation development are well established, especially in terms of nutrient requirements, uptake and fate, remarkably little is known about early embryo signaling events, intracellular or intercellular, between individual embryos in vitro or with the female reproductive tract in vivo. This contrasts with the wealth of information on cell signaling in somatic cells and tissues, as a glance at any textbook of biochemistry illustrates. This lack of information is such that our understanding of the molecular cell biology of early embryos -- a prerequisite to defining the mechanisms which regulate development at this critical stage of the life cycle -- is seriously incomplete. This volume is the first to address this issue by describing the current state of knowledge on cell signaling during mammalian early embryo development and highlighting priority areas for research.

ONE OF PEOPLE MAGAZINE'S BEST SUMMER READS 2022 5* 'A jaw-dropping memoir' - THE TELEGRAPH 'One of the maddest memoirs you'll read this year... a beautiful, warm, funny book.' -The Times 'Extraordinary' -The Guardian 'A wholly absorbing page-turner that everyone will want to read. You should probably buy two.' -Kirkus Starred Review 'A riveting debut.' -People Magazine 'By turns hilarious, wrenching, and achingly tender.' -Susan Orlean, New York Times bestselling author 'A remarkable and wise book, two memoirs braided together with such tendresse that readers will come to believe the ironic title in earnest' -LA TIMES 'Riveting and hilariously funny' - The Times For most of her life, Chrysta Bilton was one member of a small, if dysfunctional, family of four. There was her sister, Kaitlyn, her hedonistic, glamorous, gay mum Debra, and Jeffrey, who Debra hand-picked, in an LA hairdressers, to be the father of her children. During Chrysta's unstable childhood, Debra struggled to keep the family afloat and Jeffrey wandered in and out of their lives. Then, in her twenties, Chrysta discovered that her father had secretly donated his sperm over 500 times - and that she had at least 35 other siblings. A Normal Family is a captivating coming-of-age memoir about Chrysta's reckoning with the secrets both parents had carefully kept from her. Heartfelt, warm and funny, it's a story of embracing the family we have, in all the forms we find it.