Towards 4D Printing presents the current state of three-dimensional (3D) bioprinting and its recent offspring, 4D bioprinting. These are attractive approaches to tissue engineering because they hold the promise of building bulky tissue constructs with incorporated vasculature. Starting with the discussion of 3D and 4D printing of inanimate objects, the book presents several 3D bioprinting techniques and points out the challenges imposed by living cells on the bioprinting process. It argues that, in order to fine-tune the bioprinter, one needs a quantitative analysis of the conditions experienced by cells during printing. Once the printing is over, the construct evolves according to mechanisms known from developmental biology. These are described in the book along with computer simulations that aim to predict the outcome of 3D bioprinting. In addition, the book provides the latest information on the principles and applications of 4D bioprinting, such as for medical devices and assistive technology. The last chapter discusses the perspectives of the field. This book provides an up-to date description of the theoretical tools developed for the optimization of 3D bioprinting, presents the morphogenetic mechanisms responsible for the post-printing evolution of the bioprinted construct and describing computational methods for simulating this evolution, and discusses the leap from 3D to 4D bioprinting in the light of the latest developments in the field. Most importantly, Towards 4D Printing explains the importance of theoretical modeling for the progress of 3D and 4D bioprinting.

Applications of Nanotechnology in Drug Discovery and Delivery, in the Drug Discovery Update series, presents complete coverage of the application of nanotechnology in the discovery of new drugs and efficient target delivery of drugs. The book highlights recent advances of nanotechnology applications in the biomedical sciences, starting with chapters that provide the basics of nanotechnology, nanoparticles and nanocarriers. Part II deals with the application of nanotechnology in drug discovery, with an emphasis on enhanced delivery of pharmaceutical products, with Part III discussing toxicological and safety issues arising from the use of nanomaterials. This book brings together a global team of experts, making it an essential resource for researchers, drug developers, medicinal chemists, toxicologists and analytical chemists.

Microfluidic Biosensors provides a comprehensive overview of the most recent and emerging technologies in the design, fabrication and integration of microfluidics with transducers. The book discusses the design and principle of microfluidic systems and how to use them for lab-on-a-chip applications. The microfluidic fabrication technologies covered in this book provide an up-to-date view, allowing the community to think of new ways to overcome challenges faced in this field. The book's focus is on existing and emerging technologies not currently being analyzed extensively elsewhere, thus providing a unique perspective and much needed content. The editors have crafted this book to be accessible to all levels of academics, from graduate students, researchers and professors working in the fields of biosensors, microfluidics design, analytical chemistry, biomedical devices and biomedical engineering. It will also be useful for industry professionals working for microfluidic device manufacturers, or in the biosensor and biomedical devices industry.

How the Chicago International Livestock Exposition leveraged the eugenics movement to transform animals into machines and industrialize American agriculture. In 1900, the Chicago International Livestock Exposition became the epicenter of agricultural reform that focused on reinventing animals' bodies to fit a modern, industrial design. Chicago meatpackers partnered with land-grant university professors to create the International--a spectacle on the scale of a world's fair--with the intention of setting the standard for animal quality and, in doing so, transformed American agriculture. In Making Machines of Animals, Neal A. Knapp explains the motivations of both the meatpackers and the professors, describing how they deployed the International to redefine animality itself. Both professors and packers hoped to replace so-called scrub livestock with "improved" animals and created a new taxonomy of animal quality based on the burgeoning eugenics movement. The International created novel definitions of animal superiority and codified new norms, resulting in a dramatic shift in animal weight, body size, and market age. These changes transformed the animals from multipurpose to single-purpose products. These standardized animals and their dependence on off-the-farm inputs and exchanges limited farmers' choices regarding husbandry and marketing, ultimately undermining any goals for balanced farming or the maintenance and regeneration of soil fertility. Drawing on land-grant university research and publications, meatpacker records and propaganda, and newspaper and agricultural journal articles, Knapp critiques the supposed market-oriented, efficiency-driven industrial reforms proffered by the International, which were underpinned by irrational, racist ideologies. The livestock reform movement not only resulted in cruel and violent outcomes for animals but also led to twentieth-century crops and animal husbandry that were rife with inefficiencies and agricultural vulnerabilities.

Biosensors for Emerging and Re-Emerging Infectious Diseases provides a review of how cornerstone optical, electronic, nanomaterial and data processing technologies can address detection issues occurring in a pandemic event. This book gives insights into the fundamental physical, chemical and biological mechanisms needed for such a type of detection. The content covers potential biomarkers which can be used for the infectious disease diagnostic, helping readers find the appropriate approach for the diagnosis of infectious diseases. It presents a novel approach to transferring the sensing platform from lab to application in clinics and to point of care detection. The book then moves on to discuss the function and efficiency of the biosensing platform in early diagnosis of infectious diseases compared to the standard methods. The required time, the technician skills and the steps which must be performed are other key factors of the biosensing platform which are well explained.

Emerging Nanomaterials and Nano-based Drug Delivery Approaches to Combat Antimicrobial Resistance focuses on recent and emerging trends surrounding nanomaterials and nano-drug delivery approaches to combat antimicrobial resistance. The relationship between nanomaterials and antimicrobial activity needs to be deeply explored to meet the challenges of combating antimicrobial resistance. The content of this book is divided into three main topic areas, including (i) how to overcome the existing traditional approaches to combat antimicrobial resistance, (ii) applying multiple drug delivery mechanisms to target multi-drug resistant microbes, and (iii) how nanomaterials can be used as drug carriers. This is an important reference source for those looking to understand how nanotechnology plays an important role in combatting disease and infection. As antimicrobial resistance threatens the effective prevention and treatment of an ever-increasing range of infections caused by bacteria, parasites, viruses, and fungi, this is a timely resource.

Intelligent Edge Computing for Cyber Physical Applications introduces state-of-the-art research methodologies, tools and techniques, challenges, and solutions with further research opportunities in the area of edge-based cyber-physical systems. The book presents a comprehensive review of recent literature and analysis of different techniques for building edge-based CPS. In addition, it describes how edge-based CPS can be built to seamlessly interact with physical machines for optimal performance, covering various aspects of edge computing architectures for dynamic resource provisioning, mobile edge computing, energy saving scenarios, and different security issues. Sections feature practical use cases of edge-computing which will help readers understand the workings of edge-based systems in detail, taking into account the need to present intellectual challenges while appealing to a broad readership, including academic researchers, practicing engineers and managers, and graduate students.

Biomedical Sensors and Smart Sensing: A Beginner's Guide, a book in the 10-volume Primers in Biomedical Imaging Devices and Systems series, covers a wide range of interdisciplinary applications in imaging modalities, nuclear medicine, computed tomographic systems, x-ray systems, magnetic resonance imaging, ultrasound, and virtual reality. The series explores the essential fundamental techniques required to analyze and process signals and images for diagnosis, scientific discovery and medical applications. Volumes in this series cover a wide range of interdisciplinary areas, combining foundational content with practical case studies to demonstrate the applications of these technologies in real-world situations. In addition, the 10-volume series considers various medical devices, electronics, circuits, sensors and algorithms. Several applications ranging from basic biological science to clinical practice are included to facilitate ongoing research.

Modeling of Mass Transport Processes in Biological Media focuses on applications of mass transfer relevant to biomedical processes and technology-fields that require quantitative mechanistic descriptions of the delivery of molecules and drugs. This book features recent advances and developments in biomedical therapies with a focus on the associated theoretical and mathematical techniques necessary to predict mass transfer in biological systems. The book is authored by over 50 established researchers who are internationally recognized as leaders in their fields. Each chapter contains a comprehensive introductory section for those new to the field, followed by recent modeling developments motivated by empirical experimental observation. Offering a unique opportunity for the reader to access recent developments from technical, theoretical, and engineering perspectives, this book is ideal for graduate and postdoctoral researchers in academia as well as experienced researchers in biomedical industries.