Digital Human Modeling and Medicine: The Digital Twin explores the body of knowledge and state-of-the-art in Digital Human Modeling (DHM) and its applications in medicine. DHM is the science of representing humans with their physical properties, characteristics and behaviors in computerized, virtual models. These models can be used standalone or integrated with other computerized object design systems to both design or study designs of medical devices or medical device products and their relationship with humans. They serve as fast and cost-efficient computer-based tools for the assessment of human functional systems and human-system interaction. This book provides an industry first introductory and practitioner focused overview of human simulation tools, with detailed chapters describing body functional elements and organs, organ interactions and fields of application. Thus, DHM tools and a specific scientific/practical problem - functional study of the human body - are linked in a coherent framework. Eventually the book shows how DHM interfaces with common physical devices in medical practice, answering to a gap in literature and a common practitioner question. Case studies provide the applied knowledge for practitioners to make informed decisions.

Nanotechnology in Human Health: Current Research and Future Trends details the various challenges faced in human healthcare settings and how nanotechnology can be used to target and improve outcomes. The book describes the application of nanoparticles in the diagnosis of human diseases, including metabolic diseases, cancer, bacterial infection, organ degeneration and the various targeted, nano-based treatments available. Several chapters look at how microbial biofilms - a key clinical concern - can be mitigated using nanomaterials and nanotechnology. In addition, the book covers how different nanoparticle types can be utilized as therapeutic agents. This book combines materials science concepts and techniques with clinical insights and understanding to provide an interdisciplinary reference for materials scientists, microbiologists, biomedical engineers and clinicians with an interest in nanotechnology.

Management and Engineering of Critical Infrastructures focuses on two important aspects of CIS, management and engineering. The book provides an ontological foundation for the models and methods needed to design a set of systems, networks and assets that are essential for a society's functioning, and for ensuring the security, safety and economy of a nation. Various examples in agriculture, the water supply, public health, transportation, security services, electricity generation, telecommunication, and financial services can be used to substantiate dangers. Disruptions of CIS can have serious cascading consequences that would stop society from functioning properly and result in loss of life. Malicious software (a.k.a., malware), for example, can disrupt the distribution of electricity across a region, which in turn can lead to the forced shutdown of communication, health and financial sectors. Subsequently, proper engineering and management are important to anticipate possible risks and threats and provide resilient CIS. Although the problem of CIS has been broadly acknowledged and discussed, to date, no unifying theory nor systematic design methods, techniques and tools exist for such CIS.