This book focuses on mesenchymal stem cells (MSCs) of animal origin, including their isolation, characterization, and clinical applications. After briefly discussing the historical development of the field of stem cell research, it describes the basic properties and nature of stem cells particularly in relation to MSCs. In turn, it reviews materials and methods used to isolate MSCs from various sources, culture expansion, characterization and long-term storage. It also explores the therapeutic efficacy, immunomodulation and anti-inflammatory, and differentiation properties of MSCs. Importantly, the book discusses the applications of genetic engineering to enhance the efficacy and potential of MSCs in regenerative medicine. The book largely addresses the potential applications of mesenchymal stem cells in therapies for important species of domesticated animals including sheep, goats, cattle, buffalo, cats, dogs and horses. Finally, the book presents an abridgement of challenges and future prospects of stem cell research and application in medicine, in general and veterinary sciences, in particular.

Amanda Kay McVety has written the first history of the international effort to eradicate rinderpest - a devastating cattle disease - which began in the 1940s and ended in 2011. Rinderpest is the only other disease besides smallpox to have been eradicated, but very few people in the United States know about it, because it did not infect humans and never broke out in North America. In other parts of the world, however, rinderpest was a serious economic and social burden and the struggle against it was a critical part of the effort to fight poverty and hunger globally. McVety follows the deployment of rinderpest vaccines around the globe, exploring the role of the environment in the understanding of development, internationalism, and national security. She expands the standard Cold War narratives to show how these concepts were framed not only by economic and political concerns, but also by biological ones.

Evidence-based, yet entirely practical, this important new text builds upon the basics of neuroscience to describe the links between olfaction and animal behaviour, and the effects of odours in animal welfare. Animals use smells in a multitude of ways: to orientate themselves, to create social bonds, to recognise food, to initiate reproduction, and to avoid predators and imminent threats such as fire. Starting from the scientific basis of olfaction and odour perception, the book covers pheromones and behavioural tests, before describing the role of olfaction in feeding behaviour, reproduction, disease detection, and animal housing. The book: * is written in an evidence-based way, yet with an easy-to-understand style, making it accessible to non-experts * focuses on animals managed by humans, i.e. farm, zoo, lab and companion species * is illustrated by in-depth research examples of many different species This is a captivating introduction to the world of smells, suitable for advanced students, researchers, and teachers of applied ethology, animal welfare and veterinary science.

Laser therapy has become increasingly popular in small animal practice and has many benefits to the patient - including reduced inflammation, faster tissue healing and less pain, and can be used in a wide variety of conditions including wounds, sprains and fractures. Aimed at the first opinion vet, this very practical book covers the most important aspects of laser use in the practice environment. But it does so in a slightly different approach, taking two (often mis-aligned) perspectives - fundamental science and clinical applications - and combining them for a robust, useful guide to the practice of laser therapy. It includes: how lasers work on tissue, how to use them in different scenarios, how to maximise results, how to use them on different conditions including soft tissue, musculoskeletal and neurological, how to integrate lasers with other therapies, when not to use lasers or use with caution, how to choose the equipment and implement it in the practice environment and promote the treatment to clients. The book also includes case studies to illustrate the use of lasers in practice on a range of conditions in different animals including dogs, cats and exotics. Veterinary Laser Therapy in Small Animal Practice combines the clinical and scientific approaches reflected in the work of the two authors, showing how both sides together can help you have a positive impact on the patient.

Androgen Receptors is the most comprehensive and up to date volume on the topic, including discussions of the basic mechanisms of androgen-androgen receptor actions, their roles in the androgen-related diseases, and their potential clinical applications.
Key topics covered include:

-The discovery and cloning of the androgen receptor;
-Androgen receptor coregulators;
-Androgen related genes and their consensus DNA response elements;
-Basic mechanism of action including functional analyses, cellular localization and phosphorylation studies;
-Cross-talk to other signal transduction systems;
-The recent connections of androgens to women's diseases, such as osteoporosis and ovarian cancer.This book is of interest to students, basic scientists, and clinicians as both a study guide and reference of research in the androgen field. It could also be used as an advanced level text in endocrinology, urology, OBGYN, or oncology.

The Tropics are home to the greatest biodiversity in the world, but tropical species are at risk due to anthropogenic activities, mainly land use change, habitat loss, invasive species, and pathogens. Over the past 20 years, the avian malaria and related parasites (Order: Haemosporida) systems have received increased attention in the tropical regions from a diverse array of research perspectives. However, to date no attempts have been made to synthesize the available information and to propose new lines of research. This book provides such a synthesis by not only focusing on the antagonistic interactions, but also by providing conceptual chapters on topics going from avian haemosporidians life cycles and study techniques, to chapters addressing current concepts on ecology and evolution. For example, a chapter synthesizing basic biogeography and ecological niche model concepts is presented, followed by one on the island biogeography of avian haemosporidians. Accordingly, researchers and professionals interested in these antagonistic interaction systems will find both an overview of the field with special emphasis on the tropics, and access to the necessary conceptual framework for various topics in ecology, evolution and systematics. Given its conceptual perspective, the book will appeal not only to readers interested in avian haemosporidians, but also to those more generally interested in the ecology, evolution and systematics of host-parasite interactions.

This book presents the latest information on canine parasites with zoonotic potential, to help avoid human infections. Compiled by international specialists, it covers protozoa, ectoparasites and helminth species of clinical importance in dogs, as well as the state of the art in diagnosis, preventive measures and potentially necessary treatment schemes. Dogs are commonly kept in families around the world and can predispose their human companions to disease. Updating and deepening insights from other specialist literature, the book is intended for practitioners and scientists alike. It also offers practical guidance for veterinary and human physicians and highlights unexplored research areas, making it a valuable resource for students and educated non-experts with an interest in parasitology, infectiology and zoonotic pet diseases.

A Practical Approach to Neurology for the Small Animal Practitioner provides veterinary practitioners and students with a comprehensive guide to diagnosing and treating neurological cases in small animal practice. Covering the most important considerations for the general practitioner, the book includes chapters on clinical history taking, a 'stress-free' approach to the neurological examination, the most common neurological presentations in general practice, neurological emergencies, and more. It is easy to read, packed with practical hints and tips, and the information is presented using tables and bulleted lists, with accompanying images and videos to illustrate the concepts. A Practical Approach to Neurology for the Small Animal Practitioner is ideal for newly qualified vets, veterinary students, and experienced vets seeking a refresher.

With 42 chapters authored by leading international experts, Swine Nutrition: Second Edition is a comprehensive reference that covers all aspects of the nutrition of pigs. It is equally suitable as an advanced undergraduate and graduate textbook as well as a reference for anyone working in any aspect of pig production.

The book begins with a general coverage of the characteristics of swine and the swine industry with emphasis on the gastrointestinal tract. It then describes the various classes of nutrients and how these nutrients are metabolized by swine and the factors affecting their utilization. The next section covers the practical aspects of swine nutrition from birth through gestation and lactation in sows and to the feeding of adult boars. The nutritional aspects of the various feedstuffs commonly fed to swine are covered in the following section. The final chapters of the book are devoted to coverage of various techniques used in swine nutrition research.

All books on the market which have been written on the subject of botulinum toxin therapy focus on treatment of hyperactive movement disorders, autonomic dysfunction (bladder, sweat and salivary glands) and some pain indications (migraine). Reference to pre-or post -surgical indications are brief and often out-dated. No book has information on dentistry or veterinary medicine. This book provides up-to-date information on botulinum toxin therapy in surgical fields. It is also the only book in the market that provides information on botulinum toxin therapy in dentistry and veterinary medicine, furnishing the latest information. Botulinum Toxin Treatment in Surgery, Dentistry, and Veterinary Medicine appeals to many disciplines including surgery, dentistry and veterinary medicines well as appealing to neurologists and internists.

Mastitis is one of the most common diseases in dairy cattle throughout the world and it is also one of the most costly, resulting in reduced milk production and extra treatment costs. This invaluable book covers all aspects of the subject and is essential reading for veterinary surgeons and students, farmers and also those involved in the practical care of cattle.

A user-friendly reference to basic, foundational information on veterinary ophthalmology This book provides readers with a user-friendly manual to the basics of veterinary ophthalmology. It puts a focus on the most relevant information for clinical practice. Emphasizing canine ophthalmology, the book also covers the foundations of feline, equine, farm animal, and exotic animal ophthalmology. To aid in reader comprehension and information assimilation, a companion website presents review questions and the figures from the book in PowerPoint. Sample topics covered within the work include: Ophthalmic foundations: ophthalmic development and structure, physiology of the eye and vision, and ocular pharmacology and therapeutics Canine ophthalmology: canine orbit (disease and surgery), canine eyelids (disease and surgery), canine lacrimal apparatus (tear secretion and drainage), canine cornea (diseases and surgery) and canine glaucoma Other species: feline ophthalmology, equine ophthalmology, and food and fiber animal ophthalmology Ophthalmic and systemic diseases: comparative neuro-ophthalmology and systemic disease and the eye Essentials of Veterinary Ophthalmology is a useful guide for veterinary students and practitioners looking to build out their core foundations of knowledge within their specific programs of study and disciplines.

Your step-by-step guide to key emergency and critical care procedures and hands-on nursing care. Whether you need to know how to prioritise your response to a patient with multiple injuries, or you need a quick practical guide to fluid therapy, this is the go-to resource. Colour photographs of real life cases take you through the procedures and after-care, detailing essential skills. This book provides vital information for emergency and critical care situations, whether you're looking for confidence in handling emergency cases in a first-opinion practice, or a relevant, succinct guide for an emergency clinic. Be inspired to become more confident in your clinical skills and abilities, and learn how to apply your existing skills to an emergency situation.A companion website provides additional resources useful in the management of emergency and critical patients. Visit the website at www.wiley.com/go/aldridge/ecc_vet_nursing to find information charts and video clips of procedures.Written by a veterinary nurse and a veterinary surgeon who work together in the largest UK emergency clinic, this book is a practical, how-to manual with a nursing focus.

Suitable as a complete reference for nurses studying towards qualifications, or as a practical guide for daily use by veterinary nurses working in veterinary emergency and critical care.

This expertly illustrated atlas has been the go-to reference in veterinary orthopedic surgery for nearly 50 years and remains the premier resource for small animal surgical procedures. As in prior editions, Piermattei's Atlas of Surgical Approaches to the Bones and Joints of the Dog and Cat, 5th Edition is teeming with highly detailed drawings that illustrate a wide range of surgical approaches. This edition also features six all new surgical approaches and three approaches which have been expanded to illustrate the modifications required when performing orthopedic surgery on the cat. In addition to updated images throughout, fifty-five brand new illustrations accompany the new surgical approaches. As many will attest, Piermattei's Atlas is an invaluable reference that no small animal surgeon should be without. Step-by-step procedures walk you through proper positioning, anatomic landmarks, potential dangers, and increasing exposure. Primary indications listed for each surgical approach help you quickly determine which approach is most appropriate for a particular surgery. Consistent format features text on the left side and illustration plates on the right, for quick access to key information. High-quality drawings created by an expert medical artist provide exceptional clarity, realism, and detail. Cross-references throughout the text make it easy to compare surgical approaches for the same body area. Full pages dedicated to each plate allow you to more easily view anatomical parts and approaches. NEW! Six all-new approaches to surgical procedures have been added to the text. They include: Approach to the Lumbosacral Intervertebral Disk and Foramen Through a Lateral Transilial Osteotomy Approach to the Medial Region of the Shoulder Joint Minimally Invasive Approach to the Shaft of the Humerus Approach to the Lateral Aspect of the Hemipelvis Minimally Invasive Approach to the Shaft of the Femur Minimally Invasive Approach to the Shaft of the Tibia NEW! Expanded coverage of modifications required when performing orthopedic surgery on the cat include: Approach to the Lateral Aspect of the Humeral Condyle and Epicondyle in the Cat Approach to the Craniodorsal Aspect of the Hip Joint Through a Craniolateral Incision in the Cat Approach to the Shaft of the Femur in the Cat NEW! Updated images provide a better picture of various surgical approaches.

Ever since its establishment by USDA regulation in the mid-1980s, the Institutional Animal Care and Use Committee (IACUC) has evolved as the premier instrument of animal welfare oversight within research institutions in the United States. As biomedical research continuously grows, the role and impact of the IACUC has increased in scope and complexity. The IACUC Handbook has become "the Bible" for individuals when the time comes for them to serve on their institution's IACUC. It provides a foundation for understanding and implementing the many and varied responsibilities of this committee. This Third Edition comprehensively addresses the significant changes in the pertinent regulatory environment and interpretation of applicable federal laws, regulations, and policies. It provides multiple references and commentary on the new edition of the Guide for the Care and Use of Laboratory Animals, the new AVMA Guidelines for the Euthanasia of Animals: 2013 Edition, and the Office of Laboratory Animal Welfare's Frequently Asked Questions. The Third Edition also features an updated survey of IACUC practices from institutions around the United States, offering wisdom gained from their experience. In addition, it includes a chapter that provides an international perspective on how animal welfare reviews can function in other countries.

This book, which is the first volume of the book series-Livestock Diseases and Management, summarizes the prominence and implications of the emerging and transboundary animal viruses. Although the livestock plays an important role in the economy of many countries, the emerging and transboundary animal viral diseases possess a serious risk to the animal-agriculture sector and food security globally. The book describes the precise and up-to-date information on animal viral diseases which have emerged in the recent past or are re-emerging due to various environmental factors and those which are not bounded in restricted national boundaries and attained the transboundary status. The chapters summarize the recent advancements in the molecular state-of-art tools towards the development of diagnostics, prophylactics, and therapeutics of these viruses. It also explicitly describes the challenges imposed by the emerging and transboundary viral infections and our preparedness to counter them.

A completely revised and updated reference for farm animal anesthesia, sedation, and pain management The newly revised Second Edition of Farm Animal Anesthesia: Cattle, Small Ruminants, Camelids, and Pigs is a practical and easy-to-use manual for techniques associated with anesthesia and pain management in farm animal species. The new edition incorporates advances in surgical and diagnostic techniques, with the latest drugs and equipment, updated images, and new technique descriptions added throughout the book. Farm Animal Anesthesia offers additional and updated information on drug combinations and anesthetic techniques relevant to small ruminants and potbellied pigs, reflecting their growing popularity. New chapters and topics on paralytic drugs for complete muscle relaxation, use of ventilators for advanced and complex surgeries, updated local and regional anesthetic techniques, and comprehensive standing surgery and diagnostic procedures have been added. Readers will also benefit from access to a companion website with video clips demonstrating local and regional anesthetic techniques described within. The book also includes: A thorough introduction to general preanesthetic considerations for ruminants, camelids, including alpacas and llamas, and potbellied pigs A comprehensive exploration of commonly used preanesthetics and injectable anesthetics, including anticholinergics, sedatives, tranquilizers, analgesics, and injectable anesthetics Practical discussions of standing sedation and chemical restraint, including new drug combinations for reliable restraint and remote drug delivery In-depth description of the use of neuromuscular blocking drugs and monitoring in farm animals Complete review of regulatory and legal considerations of anesthetics and analgesics used in farm animals Farm Animal Anesthesia is an indispensable resource for farm animal practitioners, veterinary surgeons, veterinary anesthetists, and researchers, as well as for veterinary students and residents in surgery and anesthesia.

This book is the second volume in the series Livestock Diseases and Management, and reviews the importance and implications of animal origin viral zoonoses. It also highlights the specific etiology and epidemiology of these viral infections and discusses their various biological and mechanical transmission mechanisms. Further, the book reviews various measures for controlling viral zoonoses and examines novel therapeutic and prophylactic strategies. Discussing recent studies on the pathogenesis and host immune response to these infections, it underscores the importance of using vaccines against these viral diseases to reduce the risk of them being transmitted to humans.Lastly, it describes in detail the challenges posed by these viral infections and our readiness to face them.

The second collection of memoirs from the author who inspired the BBC series All Creatures Great and Small. This omnibus edition comprises the majority of chapters from Let Sleeping Vets Lie and Vets in Harness. Now settled into the sleepy Yorkshire village of Darrowby, and married to Helen the farmer's daughter, James Herriot thinks he's finally got himself sorted. But life as a vet in the 1930s was never going to be easy. Quite aside from his unpredictable colleagues, brothers Siegfried and Tristan Farnon, he must contend with new-fangled medical techniques, delivering calves after far too much home-made wine, and a grudge-holding dog called Magnus who never forgets. And then, with Britain on the verge of war, James faces a decision that could separate him from Darrowby - and Helen - for ever . . . Since they were first published, James Herriot's memoirs have sold millions of copies and entranced generations of animal lovers. Charming, funny and touching, All Things Bright and Beautiful is a heart-warming story of determination, love and companionship from one of Britain's best-loved authors.