Antimalarial Natural Products (Hardcover, 1st ed. 2022)

This volume begins with a short history of malaria and follows with a summary of its biology. It then traces the fascinating history of the discovery of quinine for malaria treatment, and then describes quinine's biosynthesis, its mechanism of action, and its clinical use, concluding with a discussion of synthetic antimalarial agents based on quinine's structure. It also covers the discovery of artemisinin and its development as the source of the most effective current antimalarial drug, including summaries of its synthesis and biosynthesis, its mechanism of action, and its clinical use and resistance. A short discussion of other clinically used antimalarial natural products leads to a detailed treatment of additional natural products with significant antiplasmodial activity, classified by compound type. Although the search for new antimalarial natural products from Nature's combinatorial library is challenging, it is very likely to yield new antimalarial drugs. This book thus ends by identifying ten natural products with development potential as clinical antimalarial agents.

General

Imprint:	Springer Nature Switzerland AG
Country of origin:	Switzerland
Series:	Progress in the Chemistry of Organic Natural Products, 117
Release date:	2022
First published:	2022
Editors:	A. Douglas Kinghorn • Heinz Falk • Simon Gibbons • Yoshinori Asakawa • Ji-Kai Liu • Verena M. Dirsch
Dimensions:	235 x 155mm (L x W)
Format:	Hardcover
Pages:	106
Edition:	1st ed. 2022
ISBN-13:	978-3-03-089872-4
Categories:	Books > Medicine > Other branches of medicine > Pathology > Medical parasitology Books > Science & Mathematics > Chemistry > Organic chemistry > General Books > Science & Mathematics > Biology, life sciences > Biochemistry > General Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Pharmaceutical technology Promotions
LSN:	3-03-089872-5
Barcode:	9783030898724

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