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Receptors of Cell Adhesion and Cellular Recognition, Volume 3 (Hardcover)
Loot Price: R3,116
Discovery Miles 31 160
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Receptors of Cell Adhesion and Cellular Recognition, Volume 3 (Hardcover)
Series: Biomembranes. A Multi-Volume Treatise
Expected to ship within 10 - 15 working days
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Volume 3 of Biomembranes covers receptors of cell adhesion and
cellular recognition. Proteins in the plasma membrane of cells are
heavily involved in processes of cell adhesion, but such proteins
were not actually isolated and characterized until the mid-1970s.
Since then, application of the methods of molecular biology has led
to the recognition of four major classes of cell adhesion molecule
(CAMs), the immunoglobulin super family, the cadherins, the
integrins, and the selecting. A convenient system in which to study
the importance of cell adhesion is in blood platelets where
aggregation eventually leads to thrombus formation in a process
involving a range of surface glycoproteins. Interaction with the
extracellular matrix is exemplified by CD44, the receptor for
hyaluronan, and a complex carbohydrate that is a major component of
the extracellular matrix surrounding migrating and proliferating
cells. Membrane-associated mucins have a variety of effects on cell
adhesion. The super family of immunoglobulin related proteins also
include the T cell receptors and the major histocompatibility
complex (MHC), which, together with the receptors for
immunoglobulins (the Fc receptors), are of fundamental importance
in the processes of immunity. Volume 3 of Biomembranes explores the
structures and functions of the molecules involved in these
important functions of the cell.
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