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Arterial Disorders - Definition, Clinical Manifestations, Mechanisms and Therapeutic Approaches (Hardcover, 2015 ed.)
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Arterial Disorders - Definition, Clinical Manifestations, Mechanisms and Therapeutic Approaches (Hardcover, 2015 ed.)
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As our knowledge about arterial disease is greatly expanding, the
aim of this book is to explore all aspects of arterial pathology,
including classification, clinical manifestations, pathogenesis,
and therapeutic options. The discussion of pathophysiologic
mechanisms of arterial disease is wide ranging, encompassing
hemodynamic, metabolic, humoral, inflammatory, genetic and
environmental factors. Particular emphasis is placed on recent
concepts, such as: the role of age-associated arterial alterations
in the initiation and progression of cardiovascular diseases in
older persons, the importance of mineral metabolism-bone vascular
interactions, the clinical and prognostic significance of the renal
resistive index, retinal circulation, toxemia of pregnancy as an
arterial disease, and the role of pulmonary/vascular interaction in
pulmonary hypertension and cross-talk of macrocirculation and
microcirculation in target organ involvement. Evaluation procedures
are carefully explained, and the full range of currently available
therapeutic options, including lifestyle modifications and
pharmacologic approaches, are described and appraised.
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