Books > Medicine > Clinical & internal medicine > Cardiovascular medicine
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Metallocorroles for Attenuation of Atherosclerosis (Paperback, 2012 ed.)
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Metallocorroles for Attenuation of Atherosclerosis (Paperback, 2012 ed.)
Series: Springer Theses
Expected to ship within 10 - 15 working days
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Adi Haber's thesis summarises the use of a new entity, the corrole,
to combat one of the major cardiovascular diseases,
atherosclerosis. She examines the effects of three rationally
designed corrole-metal complexes on some of the many variables
which contribute to the development of atherosclerosis. There is a
focus on both the "bad" and "good" cholesterol carriers, LDL and
HDL. Adi Haber proceeds from basic findings in pure chemistry
through biochemical and cell culture tests to in vivo examinations.
The work in this thesis shows that corroles are highly efficient
both for early and late treatment of atherosclerosis in animals.
These results will pave the way for ongoing regulated preclinical
studies focussed on the development of metallocorroles as potential
drugs for treating cardiovascular diseases.
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