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Antimicrobial Research and One Health in Africa (Hardcover, 1st ed. 2023)
Loot Price: R5,878
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Antimicrobial Research and One Health in Africa (Hardcover, 1st ed. 2023)
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Antimicrobial resistance is recognised among the world’s most
challenging problems. Despite its global spread, Africa,
specifically sub-Saharan Africa, is the most affected by this
malaise. Poor living conditions and inadequate access to sanitation
and potable water supplies are among contributing factors that have
influenced a high disease burden on the continent, requiring
extensive antimicrobials. Weak health systems and the absence of
firm policies further aggravate the problem, as the use of
antimicrobials is mostly unregulated. The increasing demand for
animal protein to meet the starving populations’ demands has also
influenced the use of these antimicrobials, including those banned
on other continents, for food animal production. The ripple effect
of indiscriminate use in humans and animals is the massive
discharge of antimicrobials, their residues,
antimicrobial-resistant microorganisms and their associated genes
into the environment. This 14-chapter unique masterpiece
presents the AMR problem in African, addressing the various
compartments of the One Health – humans, animals, and the
environment, to illustrate the need for concerted efforts in the
fight against AMR, especially in Africa. Authors from the four
cardinal points present diverse aspects of AMR in Africa, starting
with behavioural and social drivers of AMR in Africa. Antimicrobial
stewardship in an African context is also discussed. AMR in humans
is presented through studies on antibiotic-resistant neonates and
nontyphoidal Salmonella infections and the clinical relevance of
the genetics of viral resistance. Topics on AMR in mastitis,
biosecurity in animal farming and the linkage between disinfectants
and AMR are discussed. The environmental dimension of AMR is
discussed, notably in the aquatic environment, and its implication
for aquaculture and irrigation and using nanomaterials to treat
polluted waters from such environments are highlighted. Finally,
Africa’s rich floral diversity is portrayed as an eco-friendly
and cost-effective approach to combat AMR. Hopefully, the work
presented will spur greater collaboration between scientists,
environmental, animal and human health practitioners, the general
population, and policymakers to assimilate and implement the One
Health approach to combating AMR, rather than working in silos on
their various sectors
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