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Books > Medicine > Clinical & internal medicine > Cardiovascular medicine
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Myocardial Tissue Engineering (Hardcover, 2011)
Loot Price: R4,601
Discovery Miles 46 010
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Myocardial Tissue Engineering (Hardcover, 2011)
Series: Studies in Mechanobiology, Tissue Engineering and Biomaterials, 6
Expected to ship within 10 - 15 working days
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Myocardial tissue engineering (MTE), a strategy that uses materials
or material/cell constructs to prolong patients' life after cardiac
damage by supporting or restoring heart function, is continuously
improving. Common MTE strategies include an engineered vehicle',
which may be a porous scaffold or a dense substrate or patch, made
of either natural or synthetic polymeric materials. The function of
the substrate is to aid transportation of cells into the diseased
region of the heart and support their integration. This book, which
contains chapters written by leading experts in MTE, gives a
complete analysis of the area and presents the latest advances in
the field. The chapters cover all relevant aspects of MTE
strategies, including cell sources, specific TE techniques and
biomaterials used. Many different cell types have been suggested
for cell therapy in the framework of MTE, including autologous bone
marrow-derived or cardiac progenitors, as well as embryonic or
induced pluripotent stem cells, each having their particular
advantages and disadvantages. The book also considers a complete
range of biomaterials, examining different aspects of their
application in MTE, such as biocompatibility with cardiac cells,
mechanical capability and compatibility with the mechanical
properties of the native myocardium as well as degradation
behaviour in vivo and in vitro. Although a great deal of research
is being carried out in the field, this book also addresses many
questions that still remain unanswered and highlights those areas
in which further research efforts are required. The book will also
give an insight into clinical trials and possible novel cell
sources for cell therapy in MTE.
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