Carcinoma of the prostate increasingly dominates the attention of
urologists for both scientific and clinical reasons. The search for
an explanation and the prediction of the variable behaviour of the
malignant prostatic cell continues unabated. The search for more
precise tumour staging and more effective treatment is equally
vigorous. Editors Andrew Bruce and John Trachtenberg have assembled
acknowledged leaders in prostate cancer to present those areas of
direct interest to the clinician. There are a number of other
topics that might have been considered but most of these, such as
experimental tumour models or biochemical factors affecting cell
growth, still lack immediate application for the clinician.
Carcinoma of the prostate continues to have its highest incidence
in the western world, and the difference in comparison with the
incidence in the Far East appears to be real and not masked by
diagnostic or other factors. A number of other epidemiological
aspects need careful analysis: Is the incidence increasing? Is the
survival improving? Is the prognosis worse in the younger patient?
Epidemiological data are easily misused and misinterpreted so that
a precise analysis of the known facts makes an important opening
chapter to this book.
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