Before the arrival of penicillin in the 1940s, phage therapy was
one of the few weapons doctors had against bacterial infections. It
saved the life of Hollywood legend Tom Mix before being abandoned
by Western science. Now, researchers and physicians are
rediscovering the treatment, which pits phage viruses against their
natural bacterial hosts, as a potential weapon against
antibiotic-resistant infections. The Forgotten Cure traces the
story of phages from Paris, where they were discovered in 1917; to
Tbilisi, Georgia, where one of phage therapy's earliest proponents
died at the hands of Stalin; to the Nobel podium, where prominent
scientists have been recognized for breakthroughs stemming from
phage research. Today, a crop of biotech startups and dedicated
physicians is racing to win regulatory approval for phage therapy
before superbugs exhaust the last drug in the medical arsenal. Will
they clear the hurdles in time?
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