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Proteomics in Human Reproduction - Biomarkers for Millennials (Paperback, 1st ed. 2016)
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Proteomics in Human Reproduction - Biomarkers for Millennials (Paperback, 1st ed. 2016)
Series: SpringerBriefs in Reproductive Biology
Expected to ship within 10 - 15 working days
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This Brief explores the use of proteomics as a tool for biomarker
discovery in human reproduction and summarizes current findings and
trends of proteomic studies in both male and female infertility.
This simplifies this important but complex topic and equips the
novice reader with sufficient background information on the use of
proteomics in human reproduction. The up-to-date scenario on
proteomic investigations will also appeal to researchers and post
graduate students looking to keep abreast with the latest
developments in reproductive research. This review summarizes
current findings of contemporary proteomic studies on infertility
in both males and females with various reproductive pathologies,
and its use in predicting the outcome of assisted reproduction. In
human reproduction, the search for biomarkers via proteomics is a
fast-evolving approach that involves the analysis of proteins in
the reproductive tissues and fluids, such as the male gametes,
seminal plasma, ovarian and endometrial tissue, and follicular and
uterine fluid. By comparing the protein profile of a healthy,
fertile individual against that of an infertile individual, the
differentially expressed proteins may give an indication to certain
proteins that could serve as useful biomarkers that are related to
infertility. As proteomic studies continue to unravel the dynamic
proteome behind various infertility conditions, there is potential
for the discovery of prognostic markers that could ultimately help
in both natural and assisted human reproduction.
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