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Biology And Pathogenesis Of Rhabdo- And Filoviruses (Hardcover)
Loot Price: R6,134
Discovery Miles 61 340
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Biology And Pathogenesis Of Rhabdo- And Filoviruses (Hardcover)
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Rhabdoviruses and Filoviruses are single-stranded, non-segmented,
negative-strand RNA viruses, many of which cause significant
morbidity and mortality in humans and animals. Certain members of
these virus families have been used as excellent model systems to
understand the molecular biology of replication, host responses to
infections, and viral countermeasures. Rhabdoviruses have also been
used as vaccine vectors as well as oncolytic agents.Studies on
Filoviruses have now provided significant insights into how they
enter susceptible cells, replicate and cause disease, and also how
they evade the host's immune mechanisms. This book addresses the
most recent findings on Rhabdovirus and Filovirus structure,
replication mechanisms, host cell responses to virus infections and
viral countermeasures. Chapters on emerging viruses as well as
approaches for therapeutic interventions have also been
included.This book represents an authoritative text that brings
together the most recent advances on the cellular and molecular
biology of Rhabdo- and Filoviruses, including mechanisms of
pathogenesis.
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