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Research on Cognition Disorders - Theoretical and Methodological Issues (Hardcover, 1st ed. 2020)
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Research on Cognition Disorders - Theoretical and Methodological Issues (Hardcover, 1st ed. 2020)
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Research on cognitive disorders is challenging due to the
complexity of functions and numerous variables involved. The main
purpose of this book is to effectively address the methodological
issues and controversies in cognitive disorders research. First, it
reviews the concept of human cognition as a complex activity
involving interconnected mental and cerebral processes (its
systemic structure), which represent the natural and
social-cultural world by means of signs (its mediated, semiotic
nature) and result from the internalization (or appropriation by
the individual) of external actions and relations with things and
persons (its cultural-historical origin). Subsequently,
methodological issues are examined, including the use of the
systemic and network approach in neuropsychological research, the
concepts of single and double dissociation, single-case versus
group studies, problems of brain-behavioral correlations using the
lesion method and functional neuroimaging, the influence of
task-relevant variables (confounders) related to the patient (e.g.,
age, education), to the lesion (size, etiology), and to the tests
and testing conditions (ecological validity, examiners experience).
Finally, readers are given the fundamentals of statistics applied
to biomedical and psychological research, with illustrative
examples of how to calculate Z score, effect size, 2 test, t test,
Pearsons correlation coefficient, and simple linear regression.
Methodological problems in current cognitive research on early
multiple sclerosis, medial temporal lobe epilepsy, mild cognitive
impairment and dementia are examined in detail.
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