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Books > Health, Home & Family > Mind, body & spirit > Alternative therapies, healing & health
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Drug Discovery and Development - Traditional Medicine and Ethnopharmacology (Hardcover)
Loot Price: R2,600
Discovery Miles 26 000
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Drug Discovery and Development - Traditional Medicine and Ethnopharmacology (Hardcover)
Expected to ship within 12 - 19 working days
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While biotechnological advances, genomics and high throughput
screenings or combinatorial and asymmetric syntheses are opening
new opportunities in drug discovery, the industry is facing serious
innovation deficit. The total number of new molecules registered
per year has dropped in contrast to expected increase. Post
marketing failures of blockbuster drugs have become major concerns
of industries. On the other side, globally there is a major shift
to sue of traditional medicine involving complementary and
alternative therapies. Ethnopharmacology and traditional medicines
have contributed in past significantly in the process of natural
product drug discovery. There are two clear tracks where
ethnopharmacology has potential to contribute in future drug
research. First, as a discovery engine to provide new targets,
leads, and second, use of quality assured and standardized
traditional medicines. In this scenario, it is important to
understand the mechanisms of drug discovery and pharmaceutical
development with a focus on herbal drugs and neutraceutical. This
book provides historical perspective, future prospects and
significance of ethnopharmacology in drug research. It also
provides important steps in botanical drug discovery and
development including bioprospecting, quality control,
standardization, pharmaceutics, stability, pharmacokinetics, and
bioavailability with examples from ethnopharmacology and herbal
medicine. One of the important feature of this book is to give an
excellent insight to Good Laboratory and Good Clinical Practices
along with very useful summary steps involved in filing IND or NDA
of botanical products. The book also gives Regulators' perspective
of validating claims and how ethnopharmacological or traditional
medicines need different approach.
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