Chromatin immunoprecipitation sequencing (ChIP-seq), which maps the
genome-wide localization patterns of transcription factors and
epigenetic marks, is among the most widely used methods in
molecular biology. Practical Guide to ChIP-seq Data Analysis will
guide readers through the steps of ChIP-seq analysis: from quality
control, through peak calling, to downstream analyses. It will help
experimental biologists to design their ChIP-seq experiments with
the analysis in mind, and to perform the basic analysis steps
themselves. It also aims to support bioinformaticians to understand
how the data is generated, what the sources of biases are, and
which methods are appropriate for different analyses.
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