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Toll-Like Receptor Family Members and Their Ligands (Paperback, Softcover reprint of the original 1st ed. 2002)
Loot Price: R2,930
Discovery Miles 29 300
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Toll-Like Receptor Family Members and Their Ligands (Paperback, Softcover reprint of the original 1st ed. 2002)
Series: Current Topics in Microbiology and Immunology, 270
Expected to ship within 10 - 15 working days
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On occasion, the innate immune system is referred to as the
"primitive" immune system. Perhaps this has dissuaded immu
nologists from analyzing it as energetically as they have analyzed
the adaptive immune system during the past two decades. But while
its phylogenetic origins are indeed ancient, and though it is "of
the first type", there is nothing crude, nothing unsophisti cated,
and nothing "inferior" about innate immunity. On the contrary, the
innate immune system has had time to achieve a level of refinement
that is nothing short of dazzling, and a modicum of respect is at
long last due. Any immune system has two cardinal functions. It
must destroy a broad range of pathogens, and it must spare the
host. The adaptive immune system has applied a modular solution to
these problems. Each cell of the adaptive immune system is
prescreened to eliminate those that would produce untoward
interactions with self; each cell is pre-programmed to recognize a
foreign epitope that the host might one day encounter. Hence, the
duties of each individual lymphocyte are quite circumscribed.
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