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Biochemical Adaptation in Parasites (Hardcover, 1989 ed.)
Loot Price: R5,929
Discovery Miles 59 290
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Biochemical Adaptation in Parasites (Hardcover, 1989 ed.)
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In recent years, parasitologists have learned much about the way in
which parasite biochemistry differs from that of free-living
organisms. Inside the host, factors such as temperature, oxygen
tension, carbon dioxide concentration and pH have important
consequences for the biochemistry and physiology of the parasitic
organism. Strong selection pressure therefore operates at all
stages of a parasite's life cycle. The parasite's adaptational
response to this pressure is the subject of this book. Under the
headings "The nature of parasite adaptation", "Energy metabolism",
"Digestion and uptake of nutrients", "Host immunity and parasite
adaptation", "Biochemical adaptation and the magic bullet" and
"Biochemical variation in parasites", present knowledge of parasite
metabolism and how it reflects adaptation to particular
environments is surveyed. The ways in which these adaptations may
have developed during their evolution - with reference to the
modern evolution of strain variations and the development of
resistance to antiparasitic compounds - are explored, together with
immunological aspects of the host-parasite relationship and
potential metabolic targets for chemotherapy. This book should be
of use to all those involved and interested in the biochemistry of
parasites and its relation to their evolution, ecology, adaptation
and variation. Those aspects of parasite metabolism that are
attacked by anti-parasitic drugs are described, making this a
useful book for those involved in the pharmaceutical industry. This
book should be of interest to parasitologists and comparative
biochemists.
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