Originally published in 1995, this volume looks at the functioning
of the vascular endothelium, and the diseases and tissue injury
that arise as a result of inflammation and immunological responses.
The vascular endothelium is a metabolically highly active layer of
cells lining all blood vessel walls. Through its interactions with
leucocytes and other mediators, it is central to the development of
inflammatory foci and to lymphocyte trafficking around the body.
Tissue injury may arise here as a result of abnormal inflammatory
or immune responses. The potential for such injury to contribute to
autoimmune disease is discussed in this book, particularly in
relation to autoimmune vascular disease of the renal,
rheumatological and neurological systems, as well as in organ
transplantation.
General
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