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Nutrigenomics (Paperback, Softcover reprint of the original 1st ed. 2016)
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Nutrigenomics (Paperback, Softcover reprint of the original 1st ed. 2016)
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The fascinating area of Nutrigenomics describes this daily
communication between diet, food and nutrients, their metabolites
and our genome. This book describes how nutrition shapes human
evolution and demonstrates its consequences for our susceptibility
to diseases, such as diabetes and atherosclerosis. Inappropriate
diet can yield stress for our cells, tissues and organs and then it
is often associated with low-grade chronic inflammation.
Overnutrition paired with physical inactivity leads to overweight
and obesity and results in increased burden for a body that
originally was adapted for a life in the savannas of East Africa.
Therefore, this textbook does not discuss a theoretical topic in
science, but it talks about real life, and our life-long "chat"
with diet. We are all food consumers, thus each of us is concerned
by the topic of this book and should be aware of its mechanisms.
The purpose of this book is to provide an overview on the
principles of nutrigenomics and their relation to health or
disease. We are not aiming to compete with more comprehensive
textbooks on molecular nutrition, evolutionary biology, genomics,
gene regulation or metabolic diseases, but rather will focus on the
essentials and will combine, in a compact form, elements from
different disciplines. In order to facilitate the latter, we favor
a high figure-to-text ratio following the rule "a picture tells
more than thousand words". The content of this book is based on the
lecture course "Nutrigenomics", which is held since 2003 once per
year by Prof. Carlberg at the University of Eastern Finland in
Kuopio. The book is subdivided into three sections and twelve
chapters. Following the "Introduction" there are sections on the
"Molecular genetic basis" and the "Links to disease", which take a
view on nutrigenomics from the perspective of molecular mechanisms
or from the causes of metabolic diseases, respectively. Besides its
value as a textbook, Nutrigenomics will be a usefull reference for
individuals working in biomedicine.
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