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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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Glycosphingolipids Signaling (Paperback, 1st ed. 2020)
Loot Price: R4,455
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Glycosphingolipids Signaling (Paperback, 1st ed. 2020)
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This book presents the latest knowledge and the most recent
research results on glycosphingolipid (GSL)-mediated signaling.
GSLs are important constituents of the plasma membrane that exert
their distinct functions through binding to certain functional
proteins. They play a role in various human diseases and also
function as human alloantigens. Cellular GSLs are associated with
many biological functions such as cellular oncotransformation,
phenotype change, neuronal or embryonic development, regulation of
cell division, cell-cell interaction, cell attachment, adhesion,
and motility, and intracellular signaling via protein-carbohydrate
or carbohydrate-carbohydrate interactions. This book opens by
providing the key background on GSL glycan-receptor interactions
and mammalian GSL synthesis. Up-to-date information is then
presented on all aspects of GSL-dependent signaling. Viral protein
and bacterial toxin protein interactions with host cell GSLs are
examined in depth, and the concluding chapter is devoted to
signaling regulation. The book should assist in the further
development of new strategies against emerging infectious agents
and intractable diseases.
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