Neonatal Immunity (Paperback, Softcover reprint of hardcover 1st ed. 2005)

A critical review of the classic, as wells as most recent-and quite seminal-findings concerning the phenotypic and molecular characteristics of both fetal and neonatal B and T cells, the cells that mediate antibody and cellular immune responses in newborns and infants. Dr. Bona shows how the antibody response of neonates is modulated by maternal antibodies and how, in certain cases, this can cause transient or life-threatening neonatal autoimmune disease. He also describes the characteristics of neonatal tolerance induced by foreign allo- and self-antigens, which are the basis for understanding impaired infant immune response and which provide a rationale for the development of efficient neonatal vaccines. By making clear the characteristics and differences between the immune system and the immune responses of both newborns and infants, compared to those of adults, Dr. Bona offers insights and challenging hypotheses that promise to help overcome the poor responses of neonates to various antigens.

General

Imprint:	HumanaPress
Country of origin:	United States
Series:	Contemporary Immunology
Release date:	October 2010
First published:	2005
Authors:	Constantin Bona
Dimensions:	229 x 152 x 27mm (L x W x T)
Format:	Paperback
Pages:	389
Edition:	Softcover reprint of hardcover 1st ed. 2005
ISBN-13:	978-1-61737-492-0
Categories:	Books > Medicine > Clinical & internal medicine > Diseases & disorders > Immunology > General Promotions
LSN:	1-61737-492-X
Barcode:	9781617374920

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