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Pharmacology of the Skin II - Methods, Absorption, Metabolism and Toxicity, Drugs and Diseases (Paperback, Softcover reprint of the original 1st ed. 1989) Loot Price: R4,699
Discovery Miles 46 990
Pharmacology of the Skin II - Methods, Absorption, Metabolism and Toxicity, Drugs and Diseases (Paperback, Softcover reprint of...

Pharmacology of the Skin II - Methods, Absorption, Metabolism and Toxicity, Drugs and Diseases (Paperback, Softcover reprint of the original 1st ed. 1989)

D. J. Atherton

Series: Handbook of Experimental Pharmacology, 87 / 2

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Loot Price R4,699 Discovery Miles 46 990 | Repayment Terms: R440 pm x 12*

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The recent interest in the pharmacology of the skin and the treatment of its diseases has come about for two reasons. The first is a realisation that many aspects of pharmacology can be studied as easily in human skin as in animal models, where they may be more relevant to human physiology and disease. Examples of this are the action of various vasoactive agents and the isolation of mediators of inflammation after UV irradiation and antigen-induced dermatitis. The second reason is the fortuitous realisation that a pharmacological approach to the treatment of skin disease need not always await the full elucidation of aetiology and mechanism. For example, whilst the argument continued un resolved as to whether the pilo-sebaceous infection which constitutes acne was due to a blocked duct or to a simple increase in sebum production, 13-cis retinoic acid, was found quite by chance totally to ablate the disease; again, whilst cyclosporin, fresh from its triumphs in organ transplantation, has been found able to suppress the rash of psoriasis, it has resuscitated the debate on aetiology. We are therefore entering a new era in which the pharmacology and clinical pharmacology of skin are being studied as a fascinating new way of exploring questions of human physiology and pharmacology as well as for the development and study of new drugs, use of which will improve disease control and at the same time help to define pathological mechanisms.

General

Imprint: Springer-Verlag
Country of origin: Germany
Series: Handbook of Experimental Pharmacology, 87 / 2
Release date: February 2012
First published: 1989
Contributors: D. J. Atherton
Dimensions: 242 x 170 x 32mm (L x W x T)
Format: Paperback
Pages: 587
Edition: Softcover reprint of the original 1st ed. 1989
ISBN-13: 978-3-642-74056-5
Categories: Books > Medicine > Clinical & internal medicine > Dermatology
Books > Medicine > Nursing & ancillary services > Pharmacy / dispensing
Books > Medicine > General issues > Health systems & services > General practice
Books > Medicine > Pre-clinical medicine: basic sciences > Physiology > General
Books > Medicine > Other branches of medicine > Pharmacology > General
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LSN: 3-642-74056-1
Barcode: 9783642740565

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