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DNA Repair Protocols (Hardcover, 2nd Revised edition)
Loot Price: R4,582
Discovery Miles 45 820
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DNA Repair Protocols (Hardcover, 2nd Revised edition)
Series: Methods in Molecular Biology, 314
Expected to ship within 12 - 17 working days
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The first edition of this book, published in 1999 and called DNA
Repair Protocols: Eukaryotic Systems, brought together
laboratory-based methods for studying DNA damage and repair in
diverse eukaryotes: namely, two kinds of yeast, a nematode, a fruit
fly, a toad, three different plants, and human and murine cells.
This second edition of DNA Repair Protocols covers mammalian cells
only and hence its new subtitle, Mammalian Systems. There are two
reasons for this fresh emphasis, both of them pragmatic: to cater
to the interests of what is now a largely mammalocentric DNA repair
field, and to expedite editing and prod- tion of this volume.
Although DNA Repair Protocols: Mammalian Systems is a smaller book
than its predecessor, it actually contains a greater variety of
methods. Fourteen of the book's thirty-two chapters are entirely
new and areas of redundancy present in the first edition have been
eliminated here (for example, now just two chapters describe assays
for nucleotide excision repair [NER], rather than seven). All
eighteen returning chapters have been revised, many of them ext-
sively. In order to maintain a coherent arrangement of topics, the
four-part p- titioning seen in the first edition was dispensed with
and chapters concerned with ionizing radiation damage and DNA
strand breakage and repair were re- cated to near the front of the
book. Finally, an abstract now heads each chapter.
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