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Books > Science & Mathematics > Physics > Applied physics & special topics > Biophysics
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Proteins - Energy, Heat and Signal Flow (Paperback)
Loot Price: R2,058
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Proteins - Energy, Heat and Signal Flow (Paperback)
Expected to ship within 12 - 17 working days
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Computational modeling can provide a wealth of insight into how
energy flow in proteins mediates protein function. Computational
methods can also address fundamental questions related to molecular
signaling and energy flow in proteins. Proteins: Energy, Heat and
Signal Flow presents state-of-the-art computational strategies for
studying energy redistribution, signaling, and heat transport in
proteins and other molecular machines. The first of four sections
of the book address the transport of energy in molecular motors,
which function through a combination of chemically driven
large-scale conformational changes and charge transport. Focusing
on vibrational energy flow in proteins and nanostructures, the next
two sections discuss approaches based on molecular dynamics
simulations and harmonic analysis. By exploring the flow of free
energy in proteins, the last section examines the conformational
changes involved in allosteric transitions and the role of coupled
protein-solvent dynamics in conformational changes. It also
presents computational approaches developed to locate pathways
between protein structures. The integrated presentation of this
comprehensive, up-to-date volume emphasizes the interrelations
between disparate computational approaches that have contributed to
our understanding of energy flow in proteins and its role in
protein function. By defining the forefront of research in this
area, the book delineates the current challenges and opportunities
in developing novel methods and applications for the evolving study
of energy flow in molecular machines and nanomaterials.
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