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Immunosuppression and Human Malignancy (Paperback, Softcover Repri)
Loot Price: R2,786
Discovery Miles 27 860
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Immunosuppression and Human Malignancy (Paperback, Softcover Repri)
Series: Contemporary Immunology
Expected to ship within 10 - 15 working days
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This original and incisive new book by Naor and his colleagues,
Immunosuppression and Human Malignancy, offers a state-of-the-art
critical analysis of the huge body of recent research on the
immunosuppressive states associated with malignancy. Maximum
attention is paid to the role of suppressor macrophages and
lymphocytes in malignancy-related immunodepression. The central
question posed is whether immunosuppression induces carcinogenesis
and/or tumor progression, or whether it is instead the result of
these processes and/or the therapy protocols. Sources of
experimental artifacts are also evaluated. Encyclopedically
presented, each chapter of Immunosuppression and Human Malignancy
can be read independently, and each chapter features a detailed
table summarizing that chapter's major findings, providing the
reader with concise material to aid in evaluation. Investigators
initiating work in the field will find it an especially valuable
reference guide, as well as a useful tool in comparing findings
published by all the major laboratories in the field. Students of
medicine will find novel perspectives complementing the basic
information gleaned from lectures and textbooks.Since certain
treatment protocols for malignant diseases have already taken into
account cause-effect relationships between tumors and
immunodepression, physicians may also wish to use the book in
evaluating their varied treatments, or perhaps the potential
hazards associated with specific therapies. Immunosuppression and
Human Malignancy appears at a time of intensive debate on the
existence of suppressor T cells. Whereas immunosuppression per se
has been well established, the community of immunologists is
divided in its opinion about the role that suppressor T cells play
in mediating this phenomenon; at the extreme end their existence
has been completely denied. Although the book cannot definitely
resolve this problem, it provides all the arguments for both
supporters and opponents of suppressor T cells, and it may serve to
stimulate formulation of alternative immunosuppression
interpretations.
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