This book contains a comprehensive series of reviews on the
calcitonin gene-related peptide (CGRP) family of peptides. This
family of peptide hormones has a diverse and constantly expanding
range of important physiologic functions, including regulation of
blood calcium, vascular tension, feeding behavior and pain
recognition.
This volume includes chapters on:
- The adrenomedullin peptides and signalling
- Ligand binding and activation of the CGRP receptor
- Understanding amylin receptors
- The CGRP-receptor component protein
- The calcitonin peptide family
- Genetic regulation of CGRP
- Vascular actions of CGRP and adrenomedullin
- Intermedin/adrenomedullin 2 function
- CGRP and adrenomedullin as pain-related peptides
- Amylinergic control of ingestive behaviour
- Calcitonin receptors
This book discusses their receptors, physiological and
pathophysiological functions and potential as clinical targets. It
will appeal to researchers who study any of these peptides and
those with an interest in migraine therapy due to the involvement
of CGRP in this disorder. The book is unique because it brings
together research on the whole peptide family for the first time in
several years. It will be a useful reference volume for researchers
in this area. This book will also appeal to researchers in the
broader field of bioactive peptides.
General
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